Clinical Trials on Hereditary Eye Disease in Netherlands

Total 11226 results

Netherlands Institute for Innovative Ocular Surgery
Amnitrans Eyebank Rotterdam

Completed

Descemet Membrane Endothelial Keratoplasty (DMEK) (DMEK)

Corneal Dystrophies, Hereditary

Netherlands
Netherlands Institute for Innovative Ocular Surgery
Amnitrans Eyebank Rotterdam; Melles CorneaClinic Rotterdam

Completed

Descemet Stripping (Automated) Endothelial Keratoplasty (DSEK or DSAEK) (DSAEK)

Corneal Dystrophies, Hereditary

Netherlands
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

DMEK Versus DSAEK Study (DMEK)

Fuchs' Endothelial Dystrophy

Netherlands
Maastricht University Medical Center

Completed

Fuchs' Torsional Phaco Study

Fuchs' Endothelial Dystrophy | Phacoemulsification

Netherlands
UMC Utrecht
Universitaire Ziekenhuizen KU Leuven; Maastricht University Medical Center; Carl...

Completed

The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation (ADVISE)

Vision Disorders | Fuchs Dystrophy | Bullous Keratopathy | Endothelial Corneal Dystrophy

Netherlands, Belgium
Editas Medicine, Inc.

Completed

Natural History Study of CEP290-Related Retinal Degeneration

Eye Diseases | Retinal Degeneration | Eye Diseases, Hereditary | Vision Disorders | Blindness | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

United States, Netherlands, France, Germany
University of Cologne
The Clinical Trials Centre Cologne; ESCRS (European Society of Cataract and...

Not yet recruiting

Trial Comparing Cataract Surgery With Triple-DMEK in Patients With Cataract and Fuchs Endothelial Corneal Dystrophy

Cataract Surgery | Cataract and Fuchs Endothelial Corneal Dystrophy

Denmark, Germany, Netherlands, Spain
Jaeb Center for Health Research
Usher 1F Collaborative; Marjorie C. Adams Foundation

Active, not recruiting

Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F (RUSH1F)

Retinal Degeneration | Retinitis Pigmentosa | Eye Diseases, Hereditary

Switzerland, United States, Germany, Netherlands, Canada, France, Israel
Amsterdam UMC, location VUmc
ODAS

Recruiting

SPT Screening in Irradiated Hereditary Retinoblastoma Survivors

Retinoblastoma

Netherlands
Santhera Pharmaceuticals

Completed

Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)

Leber's Hereditary Optic Neuropathy (LHON)

Belgium, Netherlands, France, Germany, Norway, United Kingdom, Italy
Amsterdam UMC, location VUmc

Recruiting

Trilateral Retinoblastoma: Incidence and Outcomes (GS-TRIO)

Retinoblastoma | Trilateral Retinoblastoma

Netherlands
ProQR Therapeutics

Active, not recruiting

A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE) (ILLUMINATE)

Eye Diseases | Neurologic Manifestations | Eye Diseases, Hereditary | Sensation Disorders | Vision Disorders | Blindness | Leber Congenital Amaurosis | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

United States, Belgium, Brazil, Canada, France, Germany, Italy, Netherlands, United Kingdom
Amsterdam UMC, location VUmc

Completed

Evaluation of MRI of the Pineal Gland in Retinoblastoma (TRbFU)

Retinoblastoma

Netherlands
Santhera Pharmaceuticals

Completed

Post Authorisation Safety Study With Raxone in LHON Patients (PAROS)

Leber's Hereditary Optic Neuropathy (LHON)

Italy, Germany, France, Austria, Greece, Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

Autologous Cell Suspension Grafting Using ReCell in Vitiligo and Piebaldism Patients

Piebaldism | Segmental Vitiligo

Netherlands
Netherlands Institute for Pigment Disorders
Avita Medical

Completed

Autologous Cell Suspension Grafting Using ReCell in Vitiligo and Piebaldism Patients

Piebaldism | Segmental Vitiligo

Netherlands
Amsterdam UMC, location VUmc
University Hospital, Essen; Institut Curie; Ligue contre le cancer, France

Completed

New Strategies to Detect Cancers in Carriers of Mutations in RB1 (NIRBTEST)

Retinoblastoma | Secondary Primary Malignancies After Retinoblastoma

Netherlands, France, Germany
Amsterdam University Medical Center

Enrolling by invitation

Cognitive Functioning and Health Related Quality of Life in Retinoblastoma Survivors (RbNeuroQoL)

Retinoblastoma | Neurocognitive Dysfunction | Health-Related Behavior

Netherlands
Prothya Biosolutions

Completed

Kinetics, Efficacy and Safety of C1-Esteraseremmer-N

Hereditary Angioedema Type I | Angioneurotic Edema

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

Punchgrafting Techniques for Vitiligo (MiniSNIP)

Piebaldism | Segmental Vitiligo | Non-segmental Vitiligo

Netherlands
Jaeb Center for Health Research
Foundation Fighting Blindness

Active, not recruiting

Rate of Progression in EYS Related Retinal Degeneration (Pro-EYS)

Eye Diseases | Retinitis Pigmentosa

United States, Israel, Finland, Canada, France, Germany, Netherlands
Biogen

Completed

Efficacy and Safety of BIIB111 for the Treatment of Choroideremia (STAR)

Choroideremia

United States, Finland, France, Denmark, Netherlands, Germany, United Kingdom, Canada
ProQR Therapeutics

Recruiting

An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene. (BRIGHTEN)

Eye Diseases | Neurologic Manifestations | Retinal Degeneration | Retinal Dystrophies | Sensation Disorders | Vision Disorders | Blindness | Leber Congenital Amaurosis | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

Belgium, Brazil, Canada, Germany, Italy, Netherlands, United Kingdom
EuroBloodNet Association

Not yet recruiting

Safety and Efficacy of Mitapivat Sulfate in Adult Patients With Erythrocyte Membranopathies (SATISFY)

Hereditary Red Blood Cell Disorder (Disorder)

Denmark, Netherlands
Belite Bio, Inc

Active, not recruiting

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Adolescent Stargardt Disease (DRAGON)

Stargardt Disease 1

United States, Australia, Belgium, China, France, Germany, Hong Kong, Netherlands, Switzerland, Taiwan, United Kingdom
Wageningen University
Dutch Cancer Society; Wereld Kanker Onderzoek Fonds; Funding: Biobanking and...

Recruiting

The GEOLynch Cohort Study (GEOLynch)

Neoplasms | Colorectal Neoplasms | Lynch Syndrome | Hereditary Nonpolyposis Colorectal Cancer

Netherlands
Pharming Technologies B.V.

Completed

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema

Genetic Disorders

Netherlands
Radboud University Medical Center
Jacques and Gloria Gossweiler Foundation

Completed

Improving Gait Adaptability in Hereditary Spastic Paraplegia (Move-HSP)

Hereditary Spastic Paraplegia | Strumpell Disease

Netherlands
ProQR Therapeutics

Active, not recruiting

Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Sirius)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Netherlands, United Kingdom, Germany
Pharming Technologies B.V.

Completed

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema

Genetic Disorders

Netherlands
Pharming Technologies B.V.

Completed

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema

Hereditary Angioedema | Angioneurotic Edema

Netherlands
Maastricht University Medical Center
Radboud University Medical Center

Unknown

Non Invasive Prenatal Testing (NIPT) of Single-gene Disorders

Hereditary Disease

Netherlands
Radboud University Medical Center
Stichting Ushersyndroom

Active, not recruiting

Characterizing Rate of Progression in USHer Syndrome (CRUSH) Study (CRUSH)

Retinitis Pigmentosa | Usher Syndrome, Type 2A | USH2A

Netherlands
NightstaRx Ltd, a Biogen Company

Completed

Natural History of the Progression of Choroideremia Study (NIGHT)

Choroideremia

Finland, United States, Canada, Denmark, Netherlands, Germany, United Kingdom, Brazil, France
Amsterdam UMC, location VUmc
ZonMw: The Netherlands Organisation for Health Research and Development; Easee...

Recruiting

iSCREEN-study: Online Nurse-assisted Eye-screening in Home Healthcare

Eye Diseases

Netherlands
Janssen Research & Development, LLC
Janssen Research & Development, LLC

Active, not recruiting

Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

X-Linked Retinitis Pigmentosa

Belgium, Canada, United States, Israel, United Kingdom, Spain, Denmark, France, Italy, Netherlands, Switzerland
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Ascorbic Acid Treatment in CMT1A Trial (AATIC) (AATIC)

Charcot-Marie-Tooth Disease | Hereditary Motor and Sensory Neuropathies

Netherlands
Janssen Research & Development, LLC
Janssen Research & Development, LLC

Active, not recruiting

Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

X-Linked Retinitis Pigmentosa

United States, Canada, Israel, United Kingdom, Spain, Denmark, France, Belgium, Italy, Netherlands, Switzerland
Pharming Technologies B.V.

Completed

A Study of the Safety and Immunogenicity of Repeated rhC1INH Administration (OPERA)

Hereditary Angioedema | Genetic Disorders

Netherlands, Romania
Pharming Technologies B.V.

Completed

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema

Hereditary Angioedema | Genetic Disorders | Angioneurotic Edema

Netherlands, Romania
QLT Inc.

Completed

Repeated Treatments of QLT091001 in Subjects With Leber Congenital Amaurosis or Retinitis Pigmentosa (Extension of Study RET IRD 01)

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

Canada, United States, Germany, Netherlands, United Kingdom
University Medical Center Groningen
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); The Netherlands... and other collaborators

Completed

Chromoendoscopy to Decrease the Risk of Colorectal Neoplasia in Lynch Syndrome (ChromoLynch)

Lynch Syndrome

Netherlands
NightstaRx Ltd, a Biogen Company

Completed

Natural History of the Progression of X-Linked Retinitis Pigmentosa (XOLARIS)

X-Linked Retinitis Pigmentosa

United States, France, United Kingdom, Finland, Netherlands, Germany, Canada
Sanquin Research & Blood Bank Divisions
Radboud University Medical Center

Completed

Allogeneic Versus Autologous Serum Eye Drops (AVAnS)

Dry Eye Syndrome

Netherlands
QLT Inc.

Completed

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

United States, Canada, Germany, Netherlands, United Kingdom
Fondazione Telethon

Unknown

Natural History Study in Subjects With Usher Syndrome

Usher Syndrome, Type 1B

Italy, Netherlands, Spain
Centre Hospitalier National d'Ophtalmologie des...
Institut National de la Santé Et de la Recherche Médicale, France

Unknown

Clinical and Genetic Examination of Usher Syndrome Patients' Cohort in Europe (EURUSH)

Usher Syndrome

France, Germany, Netherlands, Portugal
Rhythm Pharmaceuticals, Inc.

Completed

Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects in the MC4R Pathway

Bardet-Biedl Syndrome | POMC Deficiency

Netherlands, United States, Germany, Canada, Puerto Rico, United Kingdom
Viridian Therapeutics, Inc.

Active, not recruiting

A Safety, Tolerability and Efficacy Study of VRDN 001 in Healthy Volunteers and Persons With Thyroid Eye Disease (TED)

Thyroid Eye Disease

United States, Spain, United Kingdom, Canada, Germany, Italy, Netherlands, Australia, France, Turkey
University Medical Center Groningen
Maastricht University Medical Center; Erasmus Medical Center; Medtronic - MITG; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) and other collaborators

Completed

Capsule Endoscopy to Screen for Small Bowel Neoplasia in Lynch Syndrome (CELSIUS)

Lynch Syndrome | Small Bowel Neoplasia

Netherlands

Clinical Trials on Hereditary Eye Disease in Netherlands

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