Clinical Trials on Hereditary Neoplastic Syndrome in Ireland

Total 762 results

National Human Genome Research Institute (NHGRI)

Completed

Microarray Analysis for Human Genetic Disease

Melanoma | Breast Neoplasm | Ovarian Neoplasm | Hereditary Neoplastic Syndrome

United States, Finland, Iceland, Sweden
St George's, University of London

Terminated

Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical Endometrial Hyperplasia and Endometrial Cancer in Women With Hereditary Non-Polyposis Colorectal Cancer or Lynch Syndrome

Endometrial Cancer | Hereditary Non-polyposis Colon Cancer (hmsh2, hmlh1, hpms1, hpms2)

United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety Study of ACZ885 in Patients With Active Recurrent or Chronic TNF-receptor Associated Periodic Syndrome (TRAPS).

TNF-receptor Associated Periodic Syndromes (TRAPS)

United Kingdom, Ireland, Italy
Royal College of Surgeons, Ireland
University College Dublin; Connolly Hospital Blanchardstown

Completed

A 2 Week, Crossover Trial of Dietary Nitrate in Obstructive Sleep Apnoea Syndrome (OSAS).

Obstructive Sleep Apnoea Syndrome

Ireland
Pharvaris Netherlands B.V.

Active, not recruiting

Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II (HAE CHAPTER-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Poland, Germany, Austria, Bulgaria, Canada, Ireland, Italy, United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney

Kidney Cancer

United Kingdom, Ireland
Cancer Trials Ireland

Active, not recruiting

Spine SABR - Dose-escalated Stereotactic Ablative Body Radiotherapy (SABR) for Solid Tumour Spine Metastases (Spine-SABR)

Solid Tumor Spine Metastases

Ireland
Boehringer Ingelheim

Completed

Pharmacokinetic Study of Interaction Between Nevirapine and Methadone in HIV-1 Infected, Opioid-dependent Adults

Acquired Immunodeficiency Syndrome

Ireland
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Lynch Syndrome | Stage III Colon Cancer AJCC v8 | Colon Adenocarcinoma | DNA Repair Disorder

United States, Puerto Rico, Germany
Pro-Change Behavior Systems

Recruiting

Previvors Recharge: A Resilience Program for Cancer Previvors (PreCharge)

Mental Health Issue | Hereditary Cancer

United States
PrecisionBiotics Group Ltd.
Atlantia Food Clinical Trials Ltd.

Completed

The Impact of a Combination of Bifidobacterium Longum 35624® and 1714™ Strains in Adults With Irritable Bowel Syndrome (IBS)

Depression, Anxiety | IBS - Irritable Bowel Syndrome

Ireland
University of Dublin, Trinity College

Completed

Exercise, Prostate Cancer and Circulating Tumour Cells (ExPeCT)

Obesity | Prostate Cancer

Ireland, United Kingdom
University College Dublin
University of Oslo; Uppsala University; Institut National de la Santé Et de la... and other collaborators

Completed

The Effect of Dietary Fat Modification on Risk Factors Associated With the Metabolic Syndrome

Metabolic Syndrome

Ireland
University College Cork

Unknown

Faecal Microbiota Transplantation in Irritable Bowel Syndrome

Irritable Bowel Syndrome

Ireland
University College Dublin

Unknown

Mater-Bronx Rapid HIV Testing Project. (M-BRiHT)

Human Immunodeficiency Virus

Ireland
University College, London
Cambridge University Hospitals NHS Foundation Trust; Sheffield Teaching Hospitals... and other collaborators

Active, not recruiting

Paediatric Sjögren Syndrome Cohort Study and Repository (PaedSSCoRe) (PaedSSCoRe)

Sjogren's Syndrome Childhood-onset

United Kingdom, Ireland
University of Dublin, Trinity College
St. James's Hospital, Ireland; Irish Cancer Society; Tallaght University Hospital and other collaborators

Completed

Exercise Prescription in Patients With Bone Metastases (Ex-Met)

Bone Metastases | Advanced Cancer

Ireland
University College Dublin
ViiV Healthcare; Mater Misericordiae University Hospital

Unknown

Triumeq As an Integrase Single Tablet Regimen in People With HIV Who Inject Drugs (TAISTR)

Human Immunodeficiency Virus

Ireland
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries

Osteoporosis | Ovarian Carcinoma | Hereditary Breast and Ovarian Cancer Syndrome

United States
DSM Nutritional Products, Inc.

Recruiting

Human Milk Oligosaccharides (HMOs) for Irritable Bowel Syndrome (IBS) (HIBS)

Irritable Bowel Syndrome | IBS - Irritable Bowel Syndrome

Ireland
University College Cork
Science Foundation Ireland; American Neurogastroenterology and Motility Society

Unknown

An Assessment of Cognitive Function in Irritable Bowel Syndrome

Irritable Bowel Syndrome

Ireland
QLT Inc.

Completed

Oral QLT091001 in Retinitis Pigmentosa (RP) Subjects With an Autosomal Dominant Mutation in Retinal Pigment Epithelial 65 Protein (RPE65)

Retinitis Pigmentosa (RP)

Canada, Ireland
St. James's Hospital, Ireland

Completed

Gastrointestinal Nutrient Transit and Enteroendocrine Function After Upper Gastrointestinal Surgery (EndoGut)

Nutrition Disorders | Esophageal Cancer | Surgery | Delayed Gastric Emptying | Appetite Disorders | Dumping Syndrome

Ireland
Royal College of Surgeons, Ireland
UNEEG Medical A/S; Science Foundation Ireland

Completed

Evaluation of the 24/7 EEG™ SubQ System in Subjects With Uncontrolled Genetic Generalised Epilepsy Syndrome

Epilepsy, Generalized

Ireland
National Cancer Institute (NCI)

Not yet recruiting

Testing ONC201 to Prevent Colorectal Cancer

Familial Adenomatous Polyposis | Colorectal Carcinoma | Colorectal Adenomatous Polyp | Multiple Adenomatous Polyps

United States
The Adelaide and Meath Hospital
University College Dublin

Completed

n-3 Polyunsaturated Fatty Acids (PUFA) Supplementation in Young Women With Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome

Ireland
Takeda

Completed

A Study of the Burden of Illness and Treatment Patterns in Teenagers and Adults With Hereditary Angioedema (BOISTERN)

Hereditary Angioedema

Belgium, Bulgaria, Estonia, Spain, Hungary, Israel, Germany, Czechia, Portugal, Greece, Lithuania, Poland, Latvia, Croatia, Slovakia, Austria, Canada, Ireland, North Macedonia, Romania, Serbia, Slovenia
Royal College of Surgeons, Ireland
University College Dublin; University of Oxford; University of Liverpool; University...

Not yet recruiting

The RolE oF Androgen Excess in MUscle Energy MetaboLism in Women With PolyCystic Ovary Syndrome (REFUEL PCOS) Study 2 (REFUEL PCOS)

Polycystic Ovary Syndrome | Metabolic Disease | Androgen Excess

Ireland
The Adelaide and Meath Hospital
University College Dublin

Completed

Adipose Tissue Gene Expression Profiles in Women With Polycystic Ovary Syndrome (PCOS) Versus Controls

Polycystic Ovary Syndrome

Ireland
Galway Clinic

Unknown

Fasting Mimicking Diet in Prostate Cancer and Metabolic Syndrome

Metabolic Syndrome | Prostate Cancer | Intermittent Fasting

Ireland
Belfast Health and Social Care Trust
Queen's University, Belfast; NHS Blood and Transplant; Northern Ireland Clinical...

Recruiting

Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration (REALIST) (REALIST)

Acute Respiratory Distress Syndrome

United Kingdom
Shire
Takeda Development Center Americas, Inc.

Recruiting

Firazyr® Patient Registry (Icatibant Outcome Survey - IOS)

Hereditary Angioedema (HAE)

France, Austria, Australia, Spain, Czechia, Italy, United Kingdom, Germany, Israel, Ireland, Brazil, Denmark, Greece, Sweden
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Decitabine Followed by Mitoxantrone Hydrochloride, Etoposide, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia

United States
The Adelaide and Meath Hospital
University College Dublin

Completed

Cardiovascular Risk Markers in Polycystic Ovary Syndrome (PCOS) (CS)

Polycystic Ovary Syndrome

Ireland
University College Dublin
St Vincent's University Hospital, Ireland; University of Dublin, Trinity College

Completed

Dose-related Effects of Vitamin D3 on Immune Responses in Patients With Clinically Isolated Syndrome (CISAVID)

Multiple Sclerosis | Clinically Isolated Syndrome

Ireland
Eisai Inc.

Completed

A Study of Decitabine Given Subcutaneously to Adults With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndrome

United States
University College Dublin

Completed

Routine Or Selective Application of a Face Mask for Preterm Infants at Birth: the ROSA Trial (ROSA)

Infant, Premature, Diseases | Respiratory Distress Syndrome, Newborn | Resuscitation | Positive-Pressure Respiration | Continuous Positive Airway Pressure

Ireland
Rachael Cusack
Grifols Biologicals, LLC

Recruiting

Microcirculation Properties of Albumin for Fluid Resuscitation in Septic Shock

Sepsis | Septic Shock | Sepsis, Severe

Ireland
Royal College of Surgeons, Ireland
University of Liverpool; University of Birmingham

Recruiting

REFUEL PCOS Study 1 (REFUEL-PCOS)

Polycystic Ovary Syndrome

Ireland
Northwell Health
Staten Island University Hospital

Completed

The Use of Heliox in Obstructive Sleep Apnea Syndrome (HOSA)

Obstructive Sleep Apnea Syndrome

United States
Ruairí Floyd
Tallaght University Hospital

Recruiting

Time-restricted Eating to Improve Metabolic Abnormalities in Polycystic Ovarian Syndrome (TimeMAP)

Insulin Resistance | Hyperinsulinemia | PCOS

Ireland
Royal College of Surgeons, Ireland

Recruiting

LEAP-Ireland Feasibility Trial of Exercise and Education for Gluteal Tendinopathy

Gluteal Tendinopathy | Trochanteric Bursitis | Greater Trochanteric Pain Syndrome

Ireland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors

Kidney Cancer

United States, Canada, Puerto Rico, Australia, Netherlands, New Zealand, Switzerland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

DNA Variations in the Gene in Young Patients With Wilms' Tumor

Kidney Cancer

United States, Canada, Puerto Rico, Australia, Netherlands, Switzerland, New Zealand
University College Cork

Unknown

Discontinuation of Long-term Medications in Older People Entering Nursing Home Care (STOPPFrail)

Frail Elderly Syndrome | Drug-Related Side Effects and Adverse Reactions | Polypharmacy | Inappropriate Prescribing

Ireland
South Eastern Health and Social Care Trust

Unknown

Negative Pressure Wound Therapy in Groin Dissection

Neoplasm Metastasis | Skin Neoplasms | Secondary Malignant Neoplasm of Lymph Node | Non-healing Surgical Wound (Disorder)

United Kingdom
Children's Health Ireland
Belfast Health and Social Care Trust; University of Edinburgh; University Hospital... and other collaborators

Recruiting

Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome (REFRESHED)

Quality of Life | Obstructive Sleep Apnea | Down Syndrome | Behavior | Adherence, Treatment

United Kingdom, Ireland
Neurovalens Ltd.
University College Dublin; Exploristics Ltd; Compliance Solutions Ltd.

Completed

Electrical Vestibular Nerve Stimulation (VeNS) Compared to Sham Control as a Means of Reducing Excess Body Weight

Obesity | Overweight | Metabolic Syndrome | Overweight and Obesity | Overweight or Obesity

Ireland
University Hospital Freiburg

Completed

Assessing Immune Function in Young Patients With Cytopenia That Did Not Respond to Treatment

Myelodysplastic Syndromes | Fanconi Anemia | Dyskeratosis Congenita | Pearson Marrow-pancreas Syndrome | Shwachman-diamond Syndrome

Spain, Germany, Switzerland, Austria, Netherlands, Italy, Czech Republic, Belgium, Denmark, Ireland
National Cancer Institute (NCI)

Active, not recruiting

Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Lynch Syndrome | Colon Mucinous Adenocarcinoma | Colon Signet Ring Cell Adenocarcinoma | Stage IIA Colon Cancer AJCC v7 | Stage IIB Colon Cancer AJCC v7 | Stage IIC Colon Cancer AJCC v7

United States, Canada, Puerto Rico, Peru, South Africa

Clinical Trials on Hereditary Neoplastic Syndrome in Ireland

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CROs in Guinea

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