Clinical Trials on Hereditary Periodic Fevers

Total 6679 results

University College London Hospitals

Completed

Muscle Structure, Function and Gait in dHMN (GAIT-dHMN)

Distal Hereditary Motor Neuropathy, Type II | Distal Hereditary Motor Neuropathy, Type V | Distal Hereditary Motor Neuronopathy Type I | Distal Hereditary Motor Neuronopathy Type VI

United Kingdom
Biolab Sanus Farmaceutica

Withdrawn

Pharmacokinetics, Pharmacodinamic and Safety of Testosterone Gel 1%

Post-menopausal Period
City, University of London
Tommy's; Boots Family Trust; Netmums; Institute of Health Visiting; Royal College...

Completed

Wellbeing in Pregnancy: Evaluating an Intervention to Improve Women's Emotional Wellbeing in Pregnancy (WiP)

Pregnant Women | Mental Health | Peripartum Period

United Kingdom
University of Palermo

Recruiting

Can Gluten/Wheat or Other Foods be Responsible for FMF Attacks

Familial Mediterranean Fever | Non-celiac Gluten Sensitivity

Italy
BioCryst Pharmaceuticals
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

A Study to Evaluate the Safety, Pharmacokinetics and Antiviral Effects of Galidesivir in Yellow Fever or COVID-19

COVID-19 | Yellow Fever

Brazil
Singapore General Hospital
Duke-NUS Graduate Medical School

Completed

The Role of Pre-existing Cross-reactive Antibodies in Determining the Efficacy of Vaccination in Humans

Encephalitis, Japanese | Yellow Fever

Singapore
Sefako Makgatho Health Sciences University

Completed

Comparing Quality of Recovery Between Desflurane & Isoflurane in Eye Surgery Patients at Dr George Mukhari Acad Hospital (DIQoR)

Quality of Recovery | Anesthesia Recovery Period

South Africa
Lucozade Ribena Suntory
King's College London

Completed

Acute Effects of Blackcurrant and Citrus Polyphenol Extracts on Postprandial Glycaemia (Glu-FX)

Postprandial Period

United Kingdom
BioMérieux

Completed

Impact of Differential and Systematic Diagnosis of Dengue, Chikungunya and Malaria on Patient Management and Antibiotic Use in West Africa

Malaria | Dengue | Chikungunya

Burkina Faso, Côte D'Ivoire
King's College London
Zoe Global Limited

Recruiting

ZOE BIOME Study: Biotics Influence on Microbiome Ecosystem

Postprandial Period | Gut Microbiome | Probiotic | Prebiotic

United Kingdom
Shanghai Yueyang Integrated Medicine Hospital

Not yet recruiting

Clinical Evaluation of ADCT to Accelerate Perioperative Rehabilitation of Pneumonectomy

Analgesia | Acupuncture Therapy | Perioperative Period | Pneumonectomy
Ewha Womans University Mokdong Hospital

Completed

Minimum Current for Train-of-four Monitoring

Anesthesia | Neuromuscular Blockade | Anesthesia Recovery Period

Korea, Republic of
GenSight Biologics

No longer available

EAP_GS010_single Patient

Leber Hereditary Optic Neuropathy (Optic, Atrophy, Hereditary, Leber)
Vissum, Instituto Oftalmológico de Alicante
Hospital Universitario La Paz; Reviva Pharmaceuticals; LASER VISION CENTER IN... and other collaborators

Unknown

Autologous Adipose-Derived Adult Stem Cell Transplantation for Corneal Diseases (A-ADAS-CT-CD)

Keratoconus | Hereditary Corneal Dystrophy

Lebanon
University of Pennsylvania
Fox Chase Cancer Center

Completed

Penn Biobank Return of Research Results Program

Cardiovascular Diseases | Cancer | Hereditary Cancer | Hereditary Cardiac Amyloidosis

United States
Novartis Pharmaceuticals

Completed

Study of Safety, Tolerability and Efficacy of DFV890 in Participants With Familial Cold Auto-inflammatory Syndrome (FCAS) (DFV890-FCAS)

Familial Cold Autoinflammatory Syndrome

United States, France, Germany
Charite University, Berlin, Germany

Completed

Safety and Tolerability of Rilonacept in Muckle-Wells Syndrome (MWS) or Schnitzler Syndrome (SchS) (ACCILTRA1)

Schnitzler Syndrome | Muckle-Wells Syndrome

Germany
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine.

Malaria | Malaria Vaccines

Ghana
Alba Maria Ropero
Centers for Disease Control and Prevention; Ministry of Public Health, Argentina

Completed

Immunogenicity of Co-administered Yellow Fever and Measles, Mumps, and Rubella (MMR) Vaccines

Vaccine Response Impaired

Argentina
CENTOGENE GmbH Rostock

Completed

Biomarker for Hereditary AngioEdema Disease (BioHAE)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | C1 Esterase Inhibitor Deficiency | HAE | Angio Edema | C4 Deficiency | Hereditary Angioedema Type III

Turkey, Armenia, Georgia, India, Peru, Poland, Romania
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Georgetown University

Recruiting

Personalized Oncology Promoting Equity for Black Lives (PROPEL)

Hereditary Cancer | Genetic Testing

United States
Instituto Nacional de Ciencias Medicas y Nutricion...

Completed

Educational Video Versus In-person Genetic Counseling for Hereditary Cancer

Hereditary Cancer | Genetic Counseling

Mexico
Vastra Gotaland Region

Active, not recruiting

AfterBabyBodyStudy- Testing Manual Examination Methods and Exercise Effects on Muscular Recovery After Pregnancy

Exercise | Pelvic Floor | Diastasis Recti | Postpartum Period

Sweden
Gazi University

Completed

The Effect of the E-Mobile Health Application on Postpartum Adaptation

Pregnant Women | Mobile Applications | Adaptation | Postpartum Period

Turkey
Neurophth Therapeutics Inc

Active, not recruiting

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND4 Mutations

Leber Hereditary Optic Neuropathy (LHON)

United States
Santhera Pharmaceuticals

Completed

Study to Assess the Efficacy and Safety of Raxone in LHON Patients (LEROS)

Leber's Hereditary Optic Neuropathy (LHON)

United States, United Kingdom, Spain, Poland, Austria, Belgium, Bulgaria, Germany, Italy, Portugal
Santhera Pharmaceuticals

Completed

Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)

Leber's Hereditary Optic Neuropathy (LHON)

Belgium, Netherlands, France, Germany, Norway, United Kingdom, Italy
Mahidol University

Completed

A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)

Optic Atrophy, Hereditary, Leber

Thailand
Huashan Hospital
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Recruiting

Real World Study of Classic Infectious Disease

Brucelloses | Epidemic Hemorrhagic Fever | Kala-Azar

China
University Hospital of Split

Completed

Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Radical Prostatectomy. (QoR)

Quality of Life | Analgesia | Anesthesia | Patient Satisfaction | Quality of Recovery | Anesthesia Recovery Period | Epidural | Postoperative Period | Radical Prostatectomy

Croatia
Centre Hospitalier Universitaire de Saint Etienne

Completed

Immunosuppression During Penetrating Keratoplasty, Using a Subconjunctival Implant Releasing Dexamethasone : Tolerance and Safety Pilot Study (IDEXACOR)

Keratoconus | Fuchs' Endothelial Dystrophy | Congenital Hereditary Stromal Dystrophy of the Cornea

France
Sanofi

Completed

Study of Live Attenuated Japanese Encephalitis Vaccine (ChimeriVax™-JE) and Yellow Fever Vaccine (STAMARIL®)

Japanese Encephalitis | Yellow Fever

Australia
The Immunobiological Technology Institute (Bio-Manguinhos)...
Rockefeller University

Recruiting

Investigation of Serious Adverse Events Following Vaccination Against Yellow Fever: Emphasis on Genetic Basis and Biological Markers

Drug-Related Side Effects and Adverse Reactions

Brazil
University of Zurich
University Hospital, Geneva; University Hospital Inselspital, Berne; Centre Hospitalier... and other collaborators

Unknown

Yellow Fever Vaccination Under Low Dose Methotrexate Therapy (MTX_YF)

Dermatologic Disorders | Rheumatic

Switzerland
Istanbul Medipol University Hospital

Active, not recruiting

EEG Results of Deep TMS in Patients With OCD

Obsessive-Compulsive Disorder | EEG With Periodic Abnormalities

Turkey
ResMed

Completed

Comparison of Modified With Conventional Adaptive Servoventilation Processes

Cheyne-Stokes Respiration | Periodic Breathing

Germany
Centre Hospitalier de Cayenne
Centre Hospitalier de Kourou; Centre Hospitalier de l'Ouest Guyanais; Centres... and other collaborators

Completed

Materno-fetal Consequences of Symptomatic Dengue in Pregnant Wowen in French Guiana (CMFdeng)

Fever | Dengue | Pregnancy Preterm | Infant, Newborn | Women | Parturition; Precipitate

French Guiana
Pro-Change Behavior Systems

Recruiting

Previvors Recharge: A Resilience Program for Cancer Previvors (PreCharge)

Mental Health Issue | Hereditary Cancer

United States
Washington State University
National Institute of Allergy and Infectious Diseases (NIAID); Washington University... and other collaborators

Recruiting

RVF and Other Emerging Infectious Diseases in East and Central Africa

Hemorrhagic Fevers, Viral | Rift Valley Fever

Congo, The Democratic Republic of the, Kenya, Tanzania, Uganda
GenSight Biologics

Completed

RESCUE and REVERSE Long-term Follow-up (RESTORE)

Leber Hereditary Optic Neuropathy

United States, France, Italy, United Kingdom, Germany
GenSight Biologics

Active, not recruiting

Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year (REFLECT)

Leber Hereditary Optic Neuropathy

Belgium, Spain, United States, France, United Kingdom, Taiwan, Italy
Santhera Pharmaceuticals

Completed

Post Authorisation Safety Study With Raxone in LHON Patients (PAROS)

Leber's Hereditary Optic Neuropathy (LHON)

Italy, Germany, France, Austria, Greece, Netherlands
GenSight Biologics

Completed

REALITY LHON Registry (REALITY)

Leber Hereditary Optic Neuropathy

United States, France, Italy, Spain, United Kingdom
Huazhong University of Science and Technology
Shiyan Taihe Hospital

Active, not recruiting

A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy

Leber Hereditary Optic Neuropathy

China
GenSight Biologics

Completed

Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients

Leber Hereditary Optic Neuropathy

France
Santhera Pharmaceuticals
European Vision Institute Clinical Research Network

Completed

Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey

Leber Hereditary Optic Neuropathy (LHON)

Belgium, France, Denmark, Italy, Slovenia
Assistance Publique - Hôpitaux de Paris

Unknown

Musculoskeletal Ultrasound of the Ankles in Erysipelas-like Erythema of Familial Mediterranean Fever (ECHOPERY)

Erysipelas

France
Seoul National University Hospital

Completed

Efficacy and Safety of Oral Valproic Acid for Retinitis Pigmentosa (VPA_RP)

Eye Diseases | Retinal Degeneration | Retinal Diseases | Retinitis Pigmentosa | Eye Disease, Hereditary

Korea, Republic of
EuroBloodNet Association

Not yet recruiting

Safety and Efficacy of Mitapivat Sulfate in Adult Patients With Erythrocyte Membranopathies (SATISFY)

Hereditary Red Blood Cell Disorder (Disorder)

Denmark, Netherlands
Applied Therapeutics, Inc.

Active, not recruiting

Pharmacodynamic EffIcacy and Clinical Benefit of AT 007 in Patients With Sorbitol Dehydrogenase (SORD) Deficiency (INSPIRE)

Hereditary Neuropathy Caused by SORD Deficiency

United States, United Kingdom, Czechia, Italy

Clinical Trials on Hereditary Periodic Fevers

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Indonesia

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Rare Diseases

Drug Interventions

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