Clinical Trials on High Grade Meningioma

Total 2712 results

University of British Columbia
British Columbia Cancer Agency; Terry Fox Research Institute

Unknown

Efficacy of Optically-guided Surgery in the Management of Early-staged Oral Cancer - COOLS TRIAL

Oral Cancer | High-grade Precancer

Canada
Colombian Foundation for Epilepsy and Neurological...

Unknown

Efficacy of Tranexamic Acid in Brain Tumor Resections (COLFIRE)

Neoplasms | Brain Tumors | Gliomas | Astrocytomas | Meningiomas

Colombia
Central Hospital, Nancy, France

Completed

Semi-automated Segmentation Methods of SSTR PET for Dosimetry Prediction (177Lumen)

Refractory Meningioma

France
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Ovarian Seromucinous Carcinoma | Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Fallopian Tube Mucinous Adenocarcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Endometrioid Adenocarcinoma | Recurrent... and other conditions

United States, Puerto Rico
City of Hope Medical Center

Completed

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

Glioblastoma | Brain Tumor | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Anaplastic Meningioma | Mixed Glioma | Brain Stem Glioma | Ependymoblastoma | Grade III Meningioma | Meningeal Hemangiopericytoma | Pineal Gland Astrocytoma

United States
University Hospital Heidelberg

Withdrawn

Comparison of Proton and Carbon Ion Radiotherapy With Advanced Photon Radiotherapy in Skull Base Meningiomas: The PINOCCHIO Trial. (PINOCCHIO)

Skull Base Meningioma

Germany
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions: A Case-control Study

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
AstraZeneca

Recruiting

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors (CYCAD-1)

ER+ HER2- Advanced Breast Cancer | High-grade Serous Ovarian Cancer (HGSOC)

United Kingdom, Korea, Republic of, Australia, United States, Spain
Case Comprehensive Cancer Center

Recruiting

Surgical Study on Upfront or Recurrent High-Grade Glioma (WHO Grade III and IV) Electrical Activity

Glioblastoma | High Grade Glioma

United States
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR); Sunnybrook Research Institute

Recruiting

Glioma Supra Marginal Incision Trial (G-SUMIT)

High Grade Glioma

Canada, United States
CCTU- Cancer Theme
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK; Experimental...

Active, not recruiting

Predicting Sites of Tumour Progression in the Invasive Margin of Glioblastomas (PRaM-GBM Study) (PRaM-GBM)

High Grade Glioma

United Kingdom
University of Washington
AstraZeneca

Recruiting

Acalabrutinib and Anti-CD19 CAR T-cell Therapy for the Treatment of B-cell Lymphoma

B-Cell Non-Hodgkin Lymphoma | Primary Mediastinal (Thymic) Large B-Cell Lymphoma | High Grade B-Cell Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Transformed Follicular Lymphoma to Diffuse...

United States
Barretos Cancer Hospital
Farmoquimica S.A.

Completed

Randomized Clinical Trial Evaluating the Efficacy of Topical Imiquimod in High Grade Cervical Intraepithelial Lesions

Cervix Cancer | High Grade Intraepithelial Neoplasia

Brazil
Brookdale University Hospital Medical Center

Unknown

Multispectral Digital Colposcope With Probe for Detection of Cervical Intraepithelial Neoplasia (MDCwProbe)

Carcinoma in Situ of Uterine Cervix | Cervical Intraepithelial Neoplasias | High Grade Cervical Intraepithelial Neoplasia

United States
University Hospital, Clermont-Ferrand

Completed

Histopathologic Evaluation of High Grade Brain Tumors by High Order Diffusion Tensor Imaging (TeDi-C2)

High Grade Brain Tumor

France
Diffusion Pharmaceuticals Inc

Terminated

Trans Sodium Crocetinate (TSC) Study of Intra-tumoral Oxygen Concentration, Safety, and Pharmacokinetics in Patients With High Grade Glioma

High Grade Glioma

United States
Institut de Cancérologie de Lorraine

Recruiting

Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia (PhotodiVIN)

Vulvar Intraepithelial Neoplasia | Vulvar High Grade Squamous Intraepithelial Lesion | Differentiated Vulvar Intraepithelial Neoplasia

France
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Predictive Factors of Visual Recovery After Paraoptic Tumors Removal (PRONOPTIC)

Tuberculum Sellae Meningioma

France
Xiangya Hospital of Central South University

Completed

Clinical Outcomes and Decision-making Choice of Skull Base Approaches for Petroclival Meningiomas

Skull Base Meningioma

China
Ethicon, Inc.
Guangzhou Bioseal Biotechnology Co., Ltd.

Completed

Phase IV Bioseal Study in Brain Tumor Surgery

Hemostasis | Meningioma Surgery

China
Alpheus Medical, Inc.

Active, not recruiting

Study to Evaluate 5-ALA Combined With CV01 Delivery of Ultrasound in Recurrent High Grade Glioma

High Grade Glioma

United States
Fundació Institut de Recerca de l'Hospital de la...

Unknown

Conservative Management in Patients Diagnosed With Grade 2 or Grade 3 CIN

Disease Progression | Papillomavirus Infections | High-Grade Squamous Intraepithelial Lesions | Neoplasm Regression, Spontaneous

Spain
Beijing Tiantan Hospital
Duke University

Unknown

Combination of Immunization and Radiotherapy for Malignant Gliomas (InSituVac1) (InSituVac1)

Glioblastoma | High Grade Glioma | Glioma, Malignant | Glioma of Brainstem

China
Mayo Clinic

Completed

Endoscopic Tri-Modal Imaging in Patients With Barrett's Esophagus (ETMI)

Early Esophageal Adenocarcinoma | Barretts Esophagus | High Grade Dysplasia

United States, Netherlands
National Cancer Institute (NCI)

Terminated

Bevacizumab and Irinotecan to Treat Brain Tumors

High-Grade Gliomas

United States
Assiut University

Unknown

Sphenoorbital Meningioma Management.

Brain Meningioma
SonoClear AS

Recruiting

SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue

Glioblastoma | High Grade Glioma | Low-grade Glioma | Brain Tumour

Germany, Slovakia, Italy
Atara Biotherapeutics

Recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

High-grade B-cell Lymphoma | MCL | Diffuse Large B-cell Lymphoma (DLBCL) | Relapsed/Refractory B-cell Non-Hodgkin Lymphoma | DLBCL/High-grade B-cell Lymphoma With MYC and BCL2 Rearrangements | Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma | LBCL With IRF4 Rearrangement | High-grade B-cell... and other conditions

United States
Rigel Pharmaceuticals
Nationwide Children's Hospital

Not yet recruiting

Study of Olutasidenib and Temozolomide in HGG

Astrocytoma | High Grade Glioma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | Spinal Tumor | Astrocytoma, Grade III | Astrocytoma, Grade IV | IDH1 Mutation | WHO Grade IV Glioma | Thalamus Tumor | IDH1 R132 | IDH1 R132C | IDH1 R132H and other conditions

United States, Australia, United Kingdom, Canada, Germany, Netherlands
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Erimos Pharmaceuticals

Completed

Terameprocol in Treating Patients With Recurrent High Grade Glioma

High Grade Glioma (III or IV)

United States
University of Southern California
National Cancer Institute (NCI); Brooklyn ImmunoTherapeutics, LLC

Active, not recruiting

IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3

Cervical Squamous Cell Carcinoma In Situ | Vulvar High Grade Squamous Intraepithelial Lesion

United States
University of Colorado, Denver

Withdrawn

Fluorescein vs. iMRI in Resection of Malignant High Grade Glioma

Glioblastoma Multiforme | Anaplastic Astrocytoma | High Grade Malignant Neoplasm

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); North American Brain Tumor Consortium

Completed

Tumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma

High Grade Glioma
Methodist Healthcare

Terminated

Gliadel Wafer, Temozolomide and Radiation Therapy for Newly Diagnosed GBM

Glioblastoma Multiforme | High-Grade Glioma

United States
Ashish Shah
National Cancer Institute (NCI); Denovo Biopharma LLC

Recruiting

DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

High Grade Glioma | Anaplastic Astrocytoma

United States
Baylor Research Institute
Taiho Oncology, Inc.

Recruiting

TAS-102 in Extrapulmonary Neuroendocrine Carcinoma (TAS-102 NEC)

High-grade Extra Pulmonary Neuroendocrine Cancer

United States
Hackensack Meridian Health
NovoCure Ltd.

Active, not recruiting

HUMC 1612: Optune NovoTTF-200A System

High Grade Glioma | Ependymoma

United States
University of California, San Francisco
Merck Sharp & Dohme LLC

Completed

Pembrolizumab-based Therapy in Previously Treated High Grade Neuroendocrine Carcinomas

High Grade Malignant Neuroendocrine Carcinoma (Diagnosis)

United States
Macarena De La Fuente, MD

Completed

Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma

Glioblastoma Multiforme | High Grade Glioma | Malignant Glioma | Anaplastic Astrocytoma

United States
Patrick C. Johnson, MD
AstraZeneca

Recruiting

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Refractory B-Cell Non-Hodgkin Lymphoma | Diffuse Large B-cell Lymphoma (DLBCL) | Grade 3b Follicular Lymphoma | Refractory Aggressive B-cell Lymphomas | Aggressive B-cell NHL | De Novo or Transformed Indolent B-cell Lymphoma | DLBCL, Nos Genetic Subtypes | T Cell/Histiocyte-rich Large B-cell Lymphoma and other conditions

United States
Andreana Holowatyj, PhD, MSCI

Recruiting

Genetics of Appendix Cancer Study (GAP)

Appendix Cancer | Appendiceal Neoplasms | Appendix Adenocarcinoma | Appendiceal Cancer | Appendiceal Adenocarcinoma | Appendix Tumor | Appendiceal Mucinous Neoplasm | Appendiceal Carcinoid Tumor | Appendiceal Neoplasm Malignant Secondary | Appendix Mucinous Neoplasm | Appendix Cancer Metastatic | Appendix NET | Low-Grade Appendix Mucinous Neoplasm and other conditions

United States
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection

Cervical Cancer | Cervical Intraepithelial Neoplasia | CIN | Human Papilloma Virus | Cervical Dysplasia | HSIL of Cervix | Cervical Neoplasm | HSIL | High-Grade Squamous Intraepithelial Lesions | High-grade Cervical Intraepithelial Neoplasia

United States, Australia
National Cancer Institute (NCI)

Terminated

Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic... and other conditions

United States
Candel Therapeutics, Inc.

Completed

Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma (BrTK02)

Glioblastoma Multiforme | High Grade Glioma | Malignant Glioma | Anaplastic Astrocytoma

United States
Mesoblast, Inc.
Quintiles, Inc.

Completed

A Prospective Study of Remestemcel-L, Ex-vivo Cultured Adult Human Mesenchymal Stromal Cells, for the Treatment of Pediatric Participants Who Have Failed to Respond to Steroid Treatment for Acute Graft-Versus-Host Disease (aGVHD)

Grade B aGVHD | Grade C aGVHD | Grade D aGVHD

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Solving Kids' Cancer; Ty Louis Campbell Foundation and other collaborators

Active, not recruiting

Phase I Study of APX005M in Pediatric CNS Tumors

Glioblastoma Multiforme | Medulloblastoma | High-grade Astrocytoma NOS | CNS Primary Tumor, Nos | Ependymoma, NOS | Diffuse Intrinsic Pontine Gliomas (DIPG)

United States
Nader Sanai
Barrow Neurological Institute; Ivy Brain Tumor Center

Recruiting

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

Glioma | Glioblastoma | High Grade Glioma | Glioma, Malignant

United States
Istituto Oncologico Veneto IRCCS
Bayer

Not yet recruiting

Regorafenib for Recurrent Grade 2 and 3 Meningioma (MIRAGE Trial) (MIRAGE)

Meningioma, Malignant

Italy
Fondazione I.R.C.C.S. Istituto Neurologico Carlo...

Recruiting

Multisession Radiosurgery in Residual/Recurrent Grade II Meningiomas. (ATM)

Meningioma Atypical

Italy

Clinical Trials on High Grade Meningioma

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