Clinical Trials on High-Grade Glioma in Spain

Total 200 results

Hospital del Río Hortega

Completed

Assessing the Effectiveness of 2D Non-Navigated Intraoperative Ultrasound in Glioma Surgery (2D-ioUS-Glio)

Glioma | Glioblastoma | Low-grade Glioma | Glioma, Malignant | High-grade Glioma

Spain
Juan M Garcia-Gomez
Hospital Universitario 12 de Octubre; Hospital Clínico Universitario de Valencia

Recruiting

BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological Levels (BIOhabitats)

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Astrocytoma, Grade IV | Glioblastoma, IDH-mutant | Glioblastoma, IDH-wildtype | Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype | Glioblastoma IDH (Isocitrate Dehydrogenase) Mutant

Spain
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young Adults (VINILO)

Refractory Low-grade Gliomas | Recurrent Low-grade Gliomas

Austria, Italy, France, Denmark, Netherlands, Spain, Switzerland, United Kingdom
Gustave Roussy, Cancer Campus, Grand Paris
Innovative Therapies For Children with Cancer Consortium

Terminated

Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults (VINILO)

Refractory Low-grade Gliomas | Recurrent Low-grade Gliomas

Austria, Italy, France, Denmark, Netherlands, Spain, Switzerland, United Kingdom
Hoffmann-La Roche

Completed

A Study of Bevacizumab (Avastin) in Combination With Temozolomide (TMZ) and Radiotherapy in Paediatric and Adolescent Participants With High-Grade Glioma

High Grade Glioma

United Kingdom, Canada, Austria, Italy, Spain, Sweden, Belgium, Denmark, France, Australia, Czechia, Hungary, Netherlands, Poland
Hospital Sant Joan de Deu
Fundació Sant Joan de Déu; Spanish National Health System

Completed

Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas

Pediatric High Risk Gliomas

Spain
Juan M Garcia-Gomez
Oslo University Hospital; Hospital Clinic of Barcelona; Hospital de Manises; Azienda... and other collaborators

Recruiting

ALBATROSS Study: International Multicenter Study for Prospective Validation of Imaging Biomarkers Calculated at Vascular Habitats of High-grade Gliomas (ALBATROSS)

Astrocytoma, Grade IV

Spain
Fundació Institut de Recerca de l'Hospital de la...

Unknown

Conservative Management in Patients Diagnosed With Grade 2 or Grade 3 CIN

Disease Progression | Papillomavirus Infections | High-Grade Squamous Intraepithelial Lesions | Neoplasm Regression, Spontaneous

Spain
Grupo Español de Investigación en Neurooncología
Pfizer

Completed

Study to Evaluate Safety and Activity of Crizotinib With Temozolomide and Radiotherapy in Newly Diagnosed Glioblastoma

Glioblastoma Multiforme (Grade IV) of Cerebellum

Spain
Institut de Recherches Internationales Servier

Active, not recruiting

Study of Vorasidenib (AG-881) in Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (INDIGO)

Recurrent Glioma | Grade 2 Glioma | Residual Glioma

United States, Canada, Spain, Italy, United Kingdom, Switzerland, Israel, Japan, Netherlands, Germany, France
Day One Biopharmaceuticals, Inc.
SIOPe Brain Tumor Group LOGGIC Consortium

Recruiting

DAY101 vs. Standard of Care Chemotherapy in Pediatric Patients With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

Low-grade Glioma

United States, Korea, Republic of, France, Germany, Spain, United Kingdom, Belgium, Denmark, Canada, Italy, Finland, Australia, Ireland, Switzerland, Netherlands, Czechia, Greece, New Zealand, Slovenia, Sweden, Hungary, Singapore, A... and more
European Organisation for Research and Treatment...
Cooperative Trials Group for Neuro-Oncology (COGNO)

Terminated

Trial in Low Grade Glioma Patients: Wait or Treat (IWOT)

Temozolomide | Low-grade Glioma | Phase III | Wait or Treat

Spain, Australia, Switzerland, France, Belgium, Italy, Austria, Netherlands, United Kingdom, Denmark
Miquel Angel Pavon Ribas
Catalan Institute of Health; Hospital del Mar

Recruiting

A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV) (RIFT-HPV)

Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III) | Human Papillomavirus (HPV) Infections | High-risk HPV | HPV-16/ 18

Spain
University of Castilla-La Mancha
Hospital Nacional de Parapléjicos de Toledo

Completed

Effect of High Frequency Electrical Currents in Healthy Subjects.

High Frequency Current

Spain
University Rovira i Virgili
Universitat de Lleida; Ministerio de Ciencia e Innovación, Spain

Unknown

Red-fleshed Apple as a Novel Anthocyanin-biofortified Food to Improve Cardiometabolic Risk Factors. (AppleCor)

High LDL-cholesterol Levels

Spain
Inovio Pharmaceuticals

Completed

REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)

Cervical Dysplasia | Cervical High Grade Squamous Intraepithelial Lesion | HSIL

United States, Spain, Lithuania, Estonia, South Africa, Argentina, Brazil, Finland, Poland, Puerto Rico
AstraZeneca

Recruiting

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors (CYCAD-1)

ER+ HER2- Advanced Breast Cancer | High-grade Serous Ovarian Cancer (HGSOC)

United States, United Kingdom, Korea, Republic of, Australia, Spain
Debiopharm International SA

Recruiting

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Astrocytoma, Grade III | Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype

Spain, United States, Switzerland
Hospital Clinic of Barcelona

Completed

Effectiveness of Prehabilitation Program for High-risk Patients Underwent Abdominal Surgery

High-risk Patient | Abdominal Surgical Patient

Spain
Inovio Pharmaceuticals

Completed

REVEAL 1 (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL) (REVEAL 1)

Cervical Dysplasia | Cervical High Grade Squamous Intraepithelial Lesion | HSIL

United States, Spain, Portugal, Italy, Philippines, Thailand, Slovakia, Lithuania, Estonia, Belgium, South Africa, Germany, Argentina, United Kingdom, Poland, Puerto Rico, Finland, Mexico, Peru
Hoffmann-La Roche

Completed

A Study to Evaluate Safety, Pharmacokinetics, and Clinical Activity of Combination of RO6870810 and Venetoclax, With or Without Rituximab, in Participants With Relapsed/Refractory DLBCL and/or High-Grade B-Cell Lymphoma and/or High Grade B-Cell Lymphoma With MYC and/or BCL2 and/or BCL6

Diffuse Large B-cell Lymphoma | High-Grade B-cell Lymphoma

United States, Spain, Australia, Denmark
Instituto de Investigacion Sanitaria La Fe

Completed

Effect of Allopurinol Administration on the Prevention of Muscle Mass Loss in Subject Immobilized.

Patients With Grade II Ankle Sprain

Spain
Hospital de Cruces
Biocruces Bizkaia Health Research Institute

Completed

Clevidipine in Neurocritical Patients (NEURO-CLEV)

High Blood Pressure

Spain
Novartis Pharmaceuticals

Recruiting

Dabrafenib and/or Trametinib Rollover Study

Melanoma | Solid Tumor | High Grade Glioma | Non Small Cell Lung Cancer | Rare Cancers

Spain, Germany, United States, Argentina, Austria, Denmark, France, Hungary, Netherlands, China, Japan, Thailand
Clinica Universidad de Navarra, Universidad de...
DNAtrix, Inc.; Alcyone Lifesciences, Inc.

Completed

Oncolytic Adenovirus, DNX-2401, for Naive Diffuse Intrinsic Pontine Gliomas

Neoadjuvant Therapy | Brainstem Glioma

Spain
Bernardino Clavo, MD, PhD
Instituto de Salud Carlos III; Instituto Tecnologico Servicios Sanitarios,... and other collaborators

Terminated

FMISO-PET in Brain Tumors and SCS Effect (FMISOPETSCS)

Malignant Glioma

Spain
InSightec

Recruiting

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM Patients

Glioblastoma | Glioma, Malignant

Italy, Spain
European Organisation for Research and Treatment...

Completed

Trabectedin for Recurrent Grade II/III Meningioma

Recurrent High Grade Meningioma

Belgium, Netherlands, France, Spain, Germany, United Kingdom, Italy, Norway, Switzerland, Austria
University of Castilla-La Mancha

Enrolling by invitation

Exercise Type That Faster Reduces Postprandial Glycemia. (GLYEXER)

Glucose, High Blood | Exercise-Induced Hyperinsulinism

Spain
Hospital Universitari de Bellvitge
Institut d'Investigació Biomèdica de Bellvitge

Unknown

E6/E7 mRNA Performance to Detect HSIL and Cost-effectiveness Analysis of This Screening Strategy in HIV + MSM (ELAVI-67)

Hiv | Anal Cancer | HPV - Anogenital Human Papilloma Virus Infection | HSIL, High Grade Squamous Intraepithelial Lesions

Spain
Instituto de Investigación Hospital Universitario...

Recruiting

"Phase I / II Study on Infusion of Natural Killer Cells After Haploidentical Transplantation in Pediatric Patients" (PHINK)

High-risk Leukemias

Spain
Array BioPharma

Completed

A Phase Ib Study of MEK162 Plus BYL719 in Adult Patients With Selected Advanced Solid Tumors

AML | Advanced and Selected Solid Tumors | High Risk and Very High Risk MDS

United States, Australia, Italy, Spain, France, Switzerland, United Kingdom
Bristol-Myers Squibb
Nektar Therapeutics

Terminated

A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer (PIVOT IO 020)

Ewing Sarcoma | Ependymoma | Medulloblastoma | Neuroblastoma | Rhabdomyosarcoma | High-grade Glioma | Leukemia and Lymphoma | Miscellaneous Brain Tumors | Miscellaneous Solid Tumors | Relapsed, Refractory Malignant Neoplasms

United States, Australia, France, Germany, Italy, Spain
Autonomic Technologies, Inc.

Completed

Pathway M-1: Sphenopalatine Ganglion Stimulation for the AcuteTreatment of High Disability Migraine Headache (Pathway M-1)

High Frequency, High Disability Migraine

Belgium, Denmark, Spain
University of Castilla-La Mancha
Ministerio de Ciencia e Innovación, Spain

Completed

The Impact of Activity Breaks on Cognitive Function, Adiposity and Fitness in Preschoolers (MOVI-HIIT)

High Intensity Interval Training | Obesity | Physical Activity | Children | Cognition | Cardiovascular

Spain
Hospital Universitario Getafe
Spanish Research Center for Respiratory Diseases

Recruiting

Global BurdEn of MechanIcal VeNtilatIon (GEMINI). VeNtilatIon (GEMINI Study) 2022 for VENTILAGROUP. (GEMINI)

Mechanical Ventilation | Usual Care | Noninvasive Positive Pressure Ventilation | High Flow Oxygen Therapy

Spain
Genentech, Inc.

Completed

A Study of GDC-0084 in Patients With Progressive or Recurrent High-Grade Glioma

Glioblastoma, Glioma

United States, Spain
University of Castilla-La Mancha
Ministerio de Ciencia e Innovación, Spain

Completed

The MOVI-HIIT Pilot Trial: The Impact of Activity Breaks on Cognitive Function, Adiposity and Fitness in Preschoolers

Cardiovascular Diseases | High Intensity Interval Training | Physical Activity | Obesity, Childhood | Cognition

Spain
Centro Universitario La Salle

Completed

Effects of High Intensity Interval Training (HIIT) vs. Inspiratory Muscle Training on the Recovery After a Maximal Apnea. ((HIIT))

Apnea | Exercise Training | High-Intensity Interval Training | Respiratory Muscle Training

Spain
University of Vigo
Bayer; Hospital Clinico Universitario de Santiago

Terminated

Comparison of Awakening Versus Bedtime Dosing of Aspirin in Pre-Hypertension or Mild Essential Hypertension

High-Normal Blood Pressure | Mild Essential Hypertension

Spain
Universidad Católica San Antonio de Murcia

Completed

Effectiveness of a Natural Ingredient on Obesity ((RACO))

Overweight and Obesity | High Blood Pressure

Spain
Clinica Universidad de Navarra, Universidad de...

Completed

Efficacy & Safety of Autologous Dendritic Cell Vaccination in Glioblastoma Multiforme After Complete Surgical Resection

Glioblastoma Multiforme

Spain
Grupo Español de Investigación en Neurooncología

Completed

Study of Sunitinib Before and During Radiotherapy in Newly Diagnosed Biopsy-only Glioblastoma Patients

Glioblastoma

Spain
Amgen

Completed

Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma

Glioblastoma or Malignant Glioma

United States, Australia, Netherlands, Germany, Spain, France
Aprea Therapeutics

Completed

p53 Activation in Platinum-Resistant High Grade Serous Ovarian Cancer, a Study of PLD With APR-246

High-grade Serous Ovarian Cancer

Spain, United Kingdom, Belgium
Fundació Sant Joan de Déu
Institut d'Investigacions Biomèdiques August Pi i Sunyer

Unknown

Safety Study of DIPG Treatment With Autologous Dendritic Cells Pulsed With Lysated Allegenic Tumor Lines

Diffuse Intrinsic Pontine Glioma

Spain
Cantex Pharmaceuticals

Recruiting

Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastoma

Glioblastoma

Spain
Hospital Infantil Universitario Niño Jesús, Madrid...
Apices Soluciones S.L.

Recruiting

Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy (AloCELYVIR)

Diffuse Intrinsic Pontine Glioma | Medulloblastoma, Childhood, Recurrent

Spain
Hospital Universitari Vall d'Hebron Research Institute

Recruiting

Individualization Flow in Patients Treated With High Flow Nasal Therapy (iFLOW) (iFLOW)

Respiratory Failure | Lung Injury | Acute Respiratory Failure | Oxygen Therapy | High-Flow Nasal Cannula

Spain
Grupo Español de Investigación en Neurooncología

Completed

Neo-adjuvant Treatment With Temozolomide and Bevacizumab Previous to Temozolomide Plus Radiation Plus Bevacizumab Therapy in Unresectable Glioblastoma

Glioblastomas

Spain

Clinical Trials on High-Grade Glioma in Spain

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