Clinical Trials on High-grade Serous Ovarian Cancer

Total 6313 results

Daiichi Sankyo, Inc.

Completed

Combination Chemotherapy With CS-1008 to Treat Ovarian Cancer

Ovarian Cancer Stage IIIC | Ovarian Cancer Stage IV

United States
University Health Network, Toronto

Completed

A Study of the Safety, Tolerability and Effectiveness of Hydroxychloroquine and Itraconazole in Platinum-resistant Epithelial Ovarian Cancer

Platinum-resistant Epithelial Ovarian Cancer

Canada
Mayo Clinic
National Cancer Institute (NCI)

Completed

Vaccine Therapy and Cyclophosphamide in Treating Patients With Stage II-III Breast or Stage II-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Breast Carcinoma | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Stage IIA Fallopian Tube Cancer | Stage... and other conditions

United States
University of Washington
AstraZeneca

Recruiting

Acalabrutinib and Anti-CD19 CAR T-cell Therapy for the Treatment of B-cell Lymphoma

B-Cell Non-Hodgkin Lymphoma | Primary Mediastinal (Thymic) Large B-Cell Lymphoma | High Grade B-Cell Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Transformed Follicular Lymphoma to Diffuse...

United States
Institut de Cancérologie de Lorraine

Recruiting

Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia (PhotodiVIN)

Vulvar Intraepithelial Neoplasia | Vulvar High Grade Squamous Intraepithelial Lesion | Differentiated Vulvar Intraepithelial Neoplasia

France
Gradalis, Inc.
Roche-Genentech

Completed

A Trial of Atezolizumab and Vigil in Patients With Advanced Gynecological Cancers

Cervical Cancer | Ovarian Cancer | Uterine Cancer | Advanced Gynecological Cancers

United States
Yonsei University

Recruiting

Bevacizumab Plus Modiifed FOLFIRINOX in Ovarian, Fallopian Tube, or Primary Peritoneal Mucinous Carcinoma

Fallopian Tube Cancer | Primary Peritoneal Cancer | Mucinous Ovarian Cancer

Korea, Republic of
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Psychosexual Intervention in Patients With Stage I-III Gynecologic or Breast Cancer

Breast Cancer | Ovarian Sarcoma | Stage III Uterine Sarcoma | Ovarian Stromal Cancer | Stage I Uterine Sarcoma | Stage II Uterine Sarcoma | Stage IIA Fallopian Tube Cancer | Stage IIB Fallopian Tube Cancer | Stage IIC Fallopian Tube Cancer | Stage IIIA Fallopian Tube Cancer | Stage IIIB Fallopian Tube Cancer and other conditions

United States
Brookdale University Hospital Medical Center

Unknown

Multispectral Digital Colposcope With Probe for Detection of Cervical Intraepithelial Neoplasia (MDCwProbe)

Carcinoma in Situ of Uterine Cervix | Cervical Intraepithelial Neoplasias | High Grade Cervical Intraepithelial Neoplasia

United States
Candel Therapeutics, Inc.

Completed

Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma (BrTK02)

Glioblastoma Multiforme | High Grade Glioma | Malignant Glioma | Anaplastic Astrocytoma

United States
Jonsson Comprehensive Cancer Center

Recruiting

Anakinra in Preventing Severe Chimeric Antigen Receptor T-Cell Related Encephalopathy Syndrome in Patients With Recurrent or Refractory Large B-cell Lymphoma

Progressive Disease | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma | Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma | Refractory High Grade B-Cell Lymphoma | Refractory Transformed Follicular... and other conditions

United States
Novartis Pharmaceuticals

Recruiting

Dabrafenib and/or Trametinib Rollover Study

Melanoma | Solid Tumor | High Grade Glioma | Non Small Cell Lung Cancer | Rare Cancers

Spain, Germany, United States, Argentina, Austria, Denmark, France, Hungary, Netherlands, China, Japan, Thailand
Imperial College London
North Eastern German Society of Gynaecological Oncology; Takeda Pharmaceuticals...

Active, not recruiting

Dual mTorc Inhibition in advanCed/Recurrent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer (of Clear Cell, Endometrioid and High Grade Serous Type, and Carcinosarcoma) (DICE)

Ovarian Neoplasms | Fallopian Tube Neoplasms | Ovarian Cancer | Fallopian Tube Cancer | Ovarian Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian Serous Adenocarcinoma | Primary Peritoneal Serous Adenocarcinoma | Primary Peritoneal Carcinoma | Ovarian Carcinosarcoma

United Kingdom, Germany
ImmunoGen, Inc.

Recruiting

First in Human Study of IMGN151 in Recurrent Endometrial Cancer and Recurrent, High-grade Serous Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers

Fallopian Tube Cancer | Endometrial Cancer | Primary Peritoneal Carcinoma | High Grade Serous Adenocarcinoma of Ovary

United States
Hospices Civils de Lyon

Not yet recruiting

Impact of Non-invasive Individualized Goal-directed Fluid Therapy on Outcomes Following Thoracic Cancer Surgery (GDFT-TCS)

High-risk Thoracic Cancer Surgery

France
ZielBio, Inc.

Completed

A Phase 1/2, First-in-Human, Open Label, Dose Escalation Study Of A CSP Targeting Functional Antibody in Solid Tumors

Ovarian Serous Cystadenocarcinoma | Solid Tumor, Adult | Ovarian Serous Adenocarcinoma | Biliary Cancer Metastatic | Pancreatic Ductal; Adenocarcinoma

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies

Fallopian Tube Cancer | Recurrent Endometrial Carcinoma | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Ovarian Sarcoma | Recurrent Uterine Sarcoma | Stage III Uterine Sarcoma | Stage IV Uterine Sarcoma | Recurrent Ovarian Epithelial Cancer | Stage IV Endometrial Carcinoma | Ovarian... and other conditions

United States
University Health Network, Toronto

Completed

18F-DCFPyL PET/CT in High-grade Epithelial Ovarian Cancer (PET HOC)

Stage IV Ovarian Cancer | Stage III Ovarian Cancer

Canada
Yonsei University
National Cancer Center, Korea; Samsung Medical Center; AstraZeneca; Seoul National... and other collaborators

Unknown

A Phase II Study of Neoadjuvant Chemotherapy Plus Durvalumab (MEDI4736) and Tremelimumab in Advanced-stage Ovarian Cancer (TRU-D) (KGOG3046)

Ovarian Cancer Stage IIIC | Ovarian Cancer Stage IV

Korea, Republic of
Chenshiling
National Natural Science Foundation of China; Comprehensive Strategic Cooperation... and other collaborators

Unknown

Repeated Injection of GnRH Agonist to Reduce Ovarian Hyperstimulation Syndrome

Infertility and at High Risk of OHSS

China
National Cancer Institute (NCI)

Completed

Bevacizumab for Recurrent Malignant Glioma

Recurrent High-Grade Gliomas | Malignant Gliomas

United States
Precigen, Inc

Recruiting

Modified Immune Cells (Autologous CAR T Cells) in Treating Patients With Advanced, Recurrent Platinum Resistant Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-Resistant Ovarian Carcinoma | Refractory Ovarian Carcinoma | Stage III Fallopian Tube... and other conditions

United States
CanariaBio Inc.
Raptim Research Pvt. Ltd

Recruiting

Oregovomab Plus Chemotherapy in Neo-adjuvant Setting in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer

Fallopian Tube Neoplasms | Ovarian Cancer | Peritoneal Carcinoma | Ovarian Serous Adenocarcinoma | Ovarian Neoplasm Epithelial

India
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Erimos Pharmaceuticals

Completed

Terameprocol in Treating Patients With Recurrent High Grade Glioma

High Grade Glioma (III or IV)

United States
University of Southern California
National Cancer Institute (NCI); Brooklyn ImmunoTherapeutics, LLC

Active, not recruiting

IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3

Cervical Squamous Cell Carcinoma In Situ | Vulvar High Grade Squamous Intraepithelial Lesion

United States
University of Colorado, Denver

Withdrawn

Fluorescein vs. iMRI in Resection of Malignant High Grade Glioma

Glioblastoma Multiforme | Anaplastic Astrocytoma | High Grade Malignant Neoplasm

United States
European Institute of Oncology

Terminated

Fenretinide in Healthy Young Women at Genetic and Familial Risk

High-Risk Cancer

Italy
ARCAGY/ GINECO GROUP

Recruiting

Retarded Surgery Following Neoadjuvant Chemotherapy in Advanced Ovarian Cancer (CHRONO)

Ovarian Cancer Stage IIIC | Ovarian Cancer Stage IV | Ovarian Cancer Stage IIIb

France
Atara Biotherapeutics

Recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

High-grade B-cell Lymphoma | MCL | Diffuse Large B-cell Lymphoma (DLBCL) | Relapsed/Refractory B-cell Non-Hodgkin Lymphoma | DLBCL/High-grade B-cell Lymphoma With MYC and BCL2 Rearrangements | Anaplastic Lymphoma Kinase-Positive Large B-Cell Lymphoma | LBCL With IRF4 Rearrangement | High-grade B-cell... and other conditions

United States
National Cancer Institute (NCI)

Completed

EF5 in Finding Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Cervical, Endometrial, or Ovarian Epithelial Cancer

Stage IV Ovarian Epithelial Cancer | Primary Peritoneal Cavity Cancer | Stage IV Endometrial Carcinoma | Stage I Ovarian Epithelial Cancer | Stage II Ovarian Epithelial Cancer | Stage III Ovarian Epithelial Cancer | Stage IA Cervical Cancer | Stage IB Cervical Cancer | Stage IIA Cervical Cancer | Stage... and other conditions

United States
SOTIO a.s.

Completed

Phase II Study DCVAC/OvCa Plus Carboplatin Gemcitabine Relapsed Platinum (Pt)-Sensitive Epithelial Ovarian Carcinoma

Ovarian Neoplasms | Ovarian Epithelial Cancer | Ovarian Cancer (OvCa)

Czechia, Poland, Germany
Paul Speiser, Prof.MD,

Completed

Early Detection of High Grade Ovarian Cancer Using Uterine Lavage EHUD Study and Duplex Sequencing (EHUD)

Carcinoma in Situ | Ovarian Cancer | Ovarian Epithelial Cancer

Austria, Czechia, Germany, Ireland
Gradalis, Inc.

Completed

Salvage Ovarian FANG™ Vaccine + Bevacizumab

Stage IV Ovarian Cancer | Stage III Ovarian Cancer

United States
Mario Negri Institute for Pharmacological Research
Hoffmann-La Roche; PharmaMar

Completed

Bevacizumab and Trabectedin +/- Carboplatin in Advanced Ovarian Cancer

Ovarian Epithelial Cancer Recurrent

Italy
Chenshiling
National Natural Science Foundation of China; Comprehensive Strategic Cooperation... and other collaborators

Unknown

Dual Trigger to Reduce Ovarian Hyperstimulation Syndrome

Infertility and at High Risk of OHSS

China
Charite University, Berlin, Germany

Withdrawn

Perioperative Assessment of Right Ventricular Function and Venous Return in Patients With Epithelial Ovarian Cancer Undergoing Cytoreductive Surgery (Gyn Right) - Pilot Study

Right Ventricular Function and Venous Return

Germany
Zumutor Biologics Inc.

Recruiting

Phase 1 Trial of ZM008 as Single Agent and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Colorectal Cancer | Esophageal Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Pancreas Adenocarcinoma | Diffuse Large B Cell Lymphoma | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Biliary Tract Cancer | High Grade Ovarian Serous Adenocarcinoma

United States
Hoffmann-La Roche

Completed

A Dose-finding Study of RO5323441 in Patients With Metastatic Treatment-Refractory Colorectal or Ovarian Cancer

Colorectal Cancer, Ovarian Cancer

Belgium, Spain, United Kingdom
Lei Li

Recruiting

Genetic Mutation in Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Microsatellite Instability | PD-L1 | Nucleotide Variant | Copy Number Variation | Insertion-deletion Variation | Genomic Structural Variation | Total Mutation Burden | PD-1

China
Ashish Shah
National Cancer Institute (NCI); Denovo Biopharma LLC

Recruiting

DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma

High Grade Glioma | Anaplastic Astrocytoma

United States
University of California, San Francisco
Merck Sharp & Dohme LLC

Completed

Pembrolizumab-based Therapy in Previously Treated High Grade Neuroendocrine Carcinomas

High Grade Malignant Neuroendocrine Carcinoma (Diagnosis)

United States
Macarena De La Fuente, MD

Completed

Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma

Glioblastoma Multiforme | High Grade Glioma | Malignant Glioma | Anaplastic Astrocytoma

United States
Inge Marie Svane

Recruiting

T-cell Therapy in Combination With Nivolumab, Relatlimab and Ipilimumab for Patients With Metastatic Ovarian Cancer

Peritoneal Cancer | Metastatic Ovarian Cancer | Metastatic Fallopian Tube Cancer

Denmark
National Cancer Institute (NCI)

Completed

Temsirolimus, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Endometrial Carcinoma | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Ovarian Sarcoma | Recurrent Ovarian Epithelial Cancer | Stage IV Endometrial Carcinoma | Ovarian Stromal Cancer | Recurrent Ovarian Germ Cell Tumor and other conditions

Canada
Georgetown University
United States Department of Defense

Suspended

A Combination Therapy Strategy to Prevent Anti-PD-1 Therapy Resistance in Metastatic Ovarian Cancer Patients

Ovarian Cancer Stage IV | Ovarian Cancer Stage III | Ovarian Cancer Stage 3

United States
AGO Study Group
Philipps University Marburg Medical Center; HSK Reasearch GmbH Wiesbaden

Completed

Randomized Multicenter Trial With SU11248 Evaluating Dosage,Tolerability,Toxicity and Effectiveness of a Multitargeted Receptor Tyrosine Kinase Inhibitor

Platinum Refractory Epithelial Ovarian Cancer | Primary Cancer of the Peritoneum | Cancer of the Fallopian Tube

Germany
Oblato, Inc.

Recruiting

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients With Recurrent High-Grade Glioma

Astrocytoma | Glioblastoma Multiforme | Oligodendroglioma | High-grade Glioma

United States
Multitude Therapeutics Inc.
Tigermed Consulting Co., Ltd

Recruiting

AMT-151 in Patients With Selected Advanced Solid Tumours

Ovarian Cancer | Ovarian Epithelial Cancer | Lung Adenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Endometrial Cancer | Advanced Cancer | Ovarian Clear Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial... and other conditions

China, Australia
Assiut University

Unknown

Primary Cyto-reductive Surgery Vs Neo-adjuvant Chemotherapy (NAC) in Epithelial Ovarian Cancer (ovarian cancer)

Advanced Cancer

Egypt
AbbVie (prior sponsor, Abbott)
Biogen

Completed

Efficacy and Safety Study of M200(Volociximab in Combination With Liposomal Doxorubicin)

Ovarian Cancer, Primary Peritoneal Cancer

United States, Australia, Belgium, Italy, Poland, Russian Federation, Spain, Sweden, Switzerland

Clinical Trials on High-grade Serous Ovarian Cancer

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Rare Diseases

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