Clinical Trials on Hormone Antagonists

Total 34360 results

Vanderbilt University Medical Center

Completed

Tamoxifen Therapy to Treat Pulmonary Arterial Hypertension (T3PAH)

Lung Diseases | Hypertension | Pulmonary Arterial Hypertension | Familial Primary Pulmonary Hypertension | Primary Pulmonary Hypertension | Estrogens | Tamoxifen | Estrogen Receptor Antagonist | Hormone Antagonists

United States
University of Groningen

Completed

DBI - Tool for Medication Reviews in Older People

Polypharmacy | Cholinergic Antagonists

Netherlands
CRG UZ Brussel
KU Leuven; Abbott; Universitätsklinikum Hamburg-Eppendorf

Completed

Oral Dydrogesterone (OD) Versus Micronized Vaginal Progesterone (MVP) for Luteal Phase Support (LPS) in IVF/ICSI

Infertility | Infertility, Female | Dydrogesterone | Genital Diseases, Female | Progesterone | Hormones | Physiological Effects of Drugs | Genital Diseases, Male | Hormones, Hormone Substitutes, and Hormone Antagonists | Progestins

Belgium
New Valley University

Completed

Progesterone Primed Endometrial Protocol Versus Gonadotropin-releasing Hormone Antagonist Protocol in Assisted Reproductive Treatments

Progesterone Primed Endometrial Protocol | Gonadotropin Releasing Hormone Antagonist Protocol | Assisted Reproductive Treatments

Egypt
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

Evaluating of CREATIF an Anti-coagulation Clinic (CREATIF)

Vitamin K Antagonist

France
ShangHai Ji Ai Genetics & IVF Institute

Completed

Live Birth Rate Between PPOS and GnRH Antagonist Protocol in Patients With Anticipated High Ovarian Response

GnRH Antagonist | IVF | PPOS

China
Bayer

Completed

To Assess Bioequivalence of Loratadine Oral Solution/Syrup Versus Claritin Peach Syrup (Bordeaux)

Histamine H1 Antagonists, Non-Sedating

Germany
University Hospital, Grenoble

Completed

Validation of a Portable Medical Device for Diagnostic in Vitro (HEMOPTIC)

Healthy Volunteer | Patients Under Vitamin K Antagonist (VKA)

France
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Pharmacokinetics of Multiple Repeated Doses of Intranasal Naloxone

Healthy Subjects | Pharmacokinetics | Opioid Antagonist

United States
Ludwig-Maximilians - University of Munich
University Hospital Heidelberg; University of Witten/Herdecke; University Hospital... and other collaborators

Recruiting

Patient-centred Deprescribing of Psychotropic, Sedative and Anticholinergic Medication in Elderly Patients With Polypharmacy (PARTNER)

Antipsychotic Agents | Antidepressive Agents | Analgesics, Opioid | Deprescriptions | Hypnotics and Sedatives | Cholinergic Antagonists

Germany
Bulent Haydardedeoglu

Terminated

In Vitro Fertilization Outcomes of Two Treatment Protocols in Women With Polycystic Ovary Syndrome (PCOS and ivf)

PCOS GnRH Antagonist and GnRH Agonist IVF/ICSI Cycles

Turkey
Fundación Clínica Shaio
Universidad El Bosque, Bogotá

Unknown

Strategies for Protamine Dosing After Anticoagulation in Cardiovascular Surgery (SEPARATION)

Anticoagulant Antagonist Toxicity

Colombia
AstraZeneca

Completed

AZD5069 Neutrophil Function Study

Chemokine Receptor 2 (CXCR2) Antagonist

United Kingdom
Bioroma

Unknown

Clomiphene Citrate Plus Gonadotropins and GnRH Antagonist Versus Flexible GnRH Antagonist Protocol Versus Microdose GnRH Agonist Protocol in Poor Responders Undergoing IVF

GnRH Antagonist | IVF | Poor Responders | Clomiphene Citrate | GnRH Agonist

Italy
Samantha Rodrigues Camargo Neves de Moura
Science Valley Research Institute

Not yet recruiting

Topical Oxybutynin for Treatment of Hyperidrosis: a Local or a Systemic Effect? (TODAY)

Hyperhidrosis | Sweat Gland Diseases | Skin Diseases | Oxybutynin | Autonomic Agents | Cholinergic Antagonists | Parasympatholytics

Brazil
UNICANCER
Breast International Group

Completed

Durvalumab and Endocrine Therapy in ER+/Her2- Breast Cancer After CD8+ Infiltration Effective Immune-Attractant Exposure (ULTIMATE)

Breast Cancer | Menopause | Estrogen Receptor Positive Tumor | Hormone Antagonist

France, Sweden, Spain
Medicalps
Icadom; AG2R La Mondiale; AVALUN; ORIADE NOVIALE; SIL-LAB INNOVATIONS; TASDA

Completed

INR at Home Measurement by the LabPad® Point-of-care in Patients on Vitamin K Antagonist Drugs (VKA) (INRADOM)

Vitamine K Antagonist (VKA) Treatment | International Normalized Ratio (INR) Measure at Home | Thromboembolic Pathology

France
Daiichi Sankyo, Inc.

Completed

The Effect of CS-3150 Exposure on Corrected QT (QTc) Interval Duration in Healthy Volunteers

Hypertension | Mineralocorticoid Receptor Antagonist

United States
Houston Fertility Institute

Completed

Single Injection of Ganirelix in Gonadotropin Intrauterine Insemination (IUI) Cycles

GnRH Antagonist | Compare Pregnancy Rates Between FSH Stimulation and FSH and

United States
ShangHai Ji Ai Genetics & IVF Institute

Recruiting

Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Patients Undergoing PGT-A

GnRH Antagonist | Preimplantation Genetic Testing | Progestin-primed Ovarian Stimulation | Euploid Rate

China
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism

Primary Aldosteronism | Mineralocorticoid Receptor Antagonist | Finerenone

China
Moustafa Mohammed Abouelea

Recruiting

Role of Triptorelin 0.1 mg as a Luteal Phase Support in Assisted Reproductive Technique After Embryo Transfer : a Randomized Controlled Trial

Effect of Adding GnRHa as Luteal Phase Support in Antagonist ART Cycles

Egypt
Brigham and Women's Hospital

Enrolling by invitation

Kinematics of Ewing Amputees

Lower Extremity Amputation | Trans-Tibial Amputation | Traumatic Lower Extremity Amputation | Agonist-Antagonist Myoneural Interface

United States
Ciusss de L'Est de l'Île de Montréal

Completed

Impact of Chronic Treatment by β1-adrenergic Antagonists on Nociceptive-Level (NOL) Index Variation After a Standardized Noxious Stimulus Under General Anesthesia (BetaNOL)

Nociception During Anesthesia in Patients Taking β1-adrenergic Antagonist Chronic Treatment

Canada
Eli Lilly and Company

Active, not recruiting

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer) (CYCLONE 3)

Urogenital Neoplasms | Prostatic Neoplasms | Neoplasm Metastasis | Enzyme Inhibitors | Antineoplastic Agents | Hormones | Physiological Effects of Drugs | Antineoplastic Agents, Hormonal | Androgens | Hormones, Hormone Substitutes, and Hormone Antagonists | Abiraterone Acetate | Steroid Synthesis Inhibitors | Cytochrome... and other conditions

China, Canada, France, United States, Australia, Czechia, Hungary, Spain, Germany, Japan, Taiwan, Netherlands, Mexico, Belgium, Korea, Republic of, Turkey, Argentina, Romania, United Kingdom, Italy, Israel, Brazil, Poland, Greece
National Institute of Arthritis and Musculoskeletal...
National Institutes of Health Clinical Center (CC)

Completed

Rilonacept for Deficiency of the Interleukin-1 Receptor Antagonist (DIRA)

DIRA

United States
Hospital Authority, Hong Kong

Unknown

The Effectiveness of Saw Palmetto and Sanmiaoshan on Benign Prostatic Hyperplasia in Chinese Patients

Prostatic Hyperplasia | Adrenergic Alpha-Antagonists

China
Wake Forest University Health Sciences
Johns Hopkins University

Terminated

Angiotensin Receptors and Age Related Mitochondrial Decline in HIV Patients (RAS-HIV)

HIV | Sarcopenia | Aging | Angiotensin Receptor Antagonists

United States
Finnish Institute for Health and Welfare

Unknown

Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder (NalGamb)

Naloxone | Gambling Disorder | Opioid Antagonist | Pathological Gambling

Finland
Universitaire Ziekenhuizen KU Leuven

Unknown

Neoadjuvant Degarelix With or Without Apalutamide (ARN-509) Followed by Radical Prostatectomy (ARNEO)

Prostate Cancer | Neoadjuvant Therapy | Prostatectomy | Androgen Antagonists

Belgium
VA Greater Los Angeles Healthcare System
AstraZeneca

Completed

Tolerability of Metoprolol-Succinate-ER and Carvedilol in COPD

Pulmonary Disease, Chronic Obstructive | Asthma | Adverse Effect of Beta-adrenoreceptor Antagonists

United States
First Affiliated Hospital, Sun Yat-Sen University

Unknown

Preventive Application of GnRH Antagonist on Early OHSS

Ovarian Hyperstimulation Syndrome | GnRH Antagonist | Aspirin | Vascular Endothelial Growth Factor | Pigment Epithelium Derived Factor

China
Rigshospitalet, Denmark

Completed

Effect of High Dose Naloxone on Secondary Hyperalgesia

Pain | Naloxone | Hyperalgesia | Opioid Antagonist

Denmark
Johannes Gutenberg University Mainz
Sanofi; Bayer; Boehringer Ingelheim; German Federal Ministry of Education and Research and other collaborators

Completed

Evaluation of Oral Anticoagulation With Vitamin K Antagonists - The thrombEVAL Study Programme (thrombEVAL)

Atrial Fibrillation | Venous Thromboembolism | Anticoagulant Antagonists, Vitamin K and Other Coagulants Causing Adverse Effects in Therapeutic Use

Germany
Wolfson Medical Center

Withdrawn

Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)

Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)
Shenyang Northern Hospital

Unknown

A Randomized, Two-arm, Open Label Study to evalUate the Effect of a Smart Phone-based Patient Support Tool On Patient AdheRence of Treatment in Stable Angina Patients Prescribed Beta-blockers in China (SUPPORT)

Medication Adherence | Mobile Applications | Stable Angina Pectoris | Adrenergic Beta-Antagonists
University Hospital Olomouc
Palacky University

Completed

Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome

Cataract | Age-related Cataract | Intraoperative Floppy Iris Syndrome | Adrenergic Receptor Antagonist Adverse Reaction

Czechia
Sun Yat-sen University

Not yet recruiting

Efficacy and Toxicity of Paclitaxel, Cisplatin Combined With Sindilimab in NACT for Locally Advanced Cervical Cancer

Cervical Cancer | Chemotherapy Effect | Neoadjuvant Therapy | Programmed Cell Death 1 Receptor / Antagonists & Inhibitors
Changi General Hospital
Singapore General Hospital

Recruiting

Outcome of Patients With Primary Aldosteronism (PA_Outcome)

Primary Aldosteronism | Hypokalemia | Chronic Renal Disease | Cardiovascular Morbidity | Mineralocorticoid Excess | Adrenalectomy; Status | Primary Aldosteronism Due to Aldosterone Producing Adenoma | Primary Aldosteronism Due to Adrenal Hyperplasia (Bilateral) | Mineralocorticoid Antagonists [Aldosterone...

Singapore
Zhejiang University
Shulan (Hangzhou) Hospital

Not yet recruiting

Assessment of AFP and PIVKA-II as Prognostic Indicators in Liver Transplantation for Hepatocellular Carcinoma

Liver Transplantation | Hepatocellular Carcinoma | Alpha-Fetoprotein | Protein Induced by Vitamin K Absence or Antagonist-II
ShangHai Ji Ai Genetics & IVF Institute

Not yet recruiting

Comparison of the Euploid Rate of Blastocyst Between PPOS and GnRH Antagonist Protocol in Women With PCOS Undergoing PGT-A

GnRH Antagonist | Polycystic Ovarian Syndrome | Preimplantation Genetic Testing | Progestin-primed Ovarian Stimulation
University of New Mexico
Kaleo Inc.

Completed

Naloxone Auto-injector as a Universal Precaution for Patients With Opioid Substance Use Disorder

Opioid-Related Disorders | Opiate Antagonist Overdose

United States
University Hospital, Limoges

Withdrawn

Efficacy of Angiotensin Receptor Blocker Following aortIc Valve Intervention for Aortic STenOsis: a Randomized mulTi-cEntric Double-blind Phase II Study (ARISTOTE)

Aortic Valve Stenosis | Transcatheter Aortic Valve Replacement | Hypertrophy, Left Ventricular | Angiotensin Receptor Antagonists | Heart Valve Prosthesis Implantation | Valsartan

France
HealthPartners Institute

Completed

Fixed Versus Variable Dosing of 4-factor Prothrombin Complex Concentrate for Emergent Warfarin Reversal (kcentra)

Hemorrhage | Acute Bleeding on Long-Term Anticoagulation Therapy | Significant Bleeding in Patients With a Coagulopathy (Prolonged Thrombin Time) | Urgent Reversal of Vitamin K Antagonist (VKA) Anticoagulation

United States
University of Sao Paulo

Terminated

Switch of Renin-Angiotensin System Inhibitors in Patients With Covid-19 (SWITCH-COVID)

Covid19 | Angiotensin II Receptor Antagonist Adverse Reaction

Brazil
University Ghent

Completed

SIBlos EXtension Study (SIBEX)

Bone Density | Thyroid Hormones | Gonadal Steroid Hormones

Belgium
Kavaklıdere Umut Hospital
Ankara University

Unknown

Clinical Study Investigating the Effect of Sodium Nitroprusside Infusion on Thyroidal Function

Thyroid Hormones | Nitroprusside

Turkey
Allergan

Completed

A Study of Armour® Thyroid Compared to Synthetic T4 (Levothyroxine) in Previously Hypothyroid Participants

Hypothyroidism | Thyroid Disease | Euthyroid | Thyroid Gland | Thyroid Hormones

United States
Helwan University

Recruiting

Efficacy of Phentolamine in Prevention of Contrast-Associated Acute Kidney Injury After Complex PCI

Coronary Artery Disease | Acute Coronary Syndrome | Adrenergic Receptor Antagonist Adverse Reaction | CA-AKI - Contrast-Associated Acute Kidney Injury

Egypt
Ascendis Pharma Endocrinology Division A/S

Completed

A Phase 3 Trial of the Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)

Endocrine System Diseases | Pituitary Diseases | Hormones | Growth Hormone Deficiency, Pediatric | hGH (Human Growth Hormone)

United States, Armenia, Australia, Belarus, Bulgaria, Georgia, Greece, Italy, New Zealand, Poland, Romania, Russian Federation, Turkey, Ukraine

Clinical Trials on Hormone Antagonists

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CROs in Burkina Faso

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