Clinical Trials on Hypercholesterinemia

Total 1178 results

Regeneron Pharmaceuticals
Sanofi

Completed

Study of the Efficacy and Safety of Alirocumab (REGN727/SAR236553) in Combination With Other Lipid-modifying Treatment (LMT) (ODYSSEY OPTIONS I)

Hypercholesterolemia

United States, France, Italy, Germany, Spain, Mexico, Canada, United Kingdom, Australia
Chiang Mai University

Completed

Comparison of the Efficacy of Plant Sterol-Enriched Soymilk Versus Plain Soymilk in Volunteers With High LDL-Cholesterol (sterols)

Hypercholesterolemia

Thailand
Gachon University Gil Medical Center

Completed

Vascular and Metabolic Effects of Vytorin vs Simvastatin

Hypercholesterolemia

Korea, Republic of
Seoul National University Hospital

Completed

Influence of OATP1B1 and BRCP Genotype on Rosuvastatin PK, PD and Lipidomics in Hyperlipidemic Patients

Hypercholesterolemia

Korea, Republic of
Aegerion Pharmaceuticals, Inc.

Completed

The Safety & Efficacy of Combination BMS-201038 (AEGR-733) & Ezetimibe vs. Monotherapy in Moderate Hypercholesterolemia

Hypercholesterolemia

United States
Novartis Pharmaceuticals

Completed

Safety, Tolerability, PK and PD of LGT209 in Healthy Volunteers and Patients With Hypercholesterolemia

Hypercholesterolemia

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Pharmacokinetic of Alirocumab SAR236553 (REGN727) Administered Subcutaneously at 3 Different Injection Sites in Healthy Subjects

Hypercholesterolemia

United Kingdom
Bronx VA Medical Center

Completed

Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) Cholesterol

Hypercholesterolemia

United States
University of Jena
German Federal Ministry of Education and Research

Completed

Intervention With Lupin Kernel Fibre in Hypercholesterolemic Subjects

Hypercholesterolemia

Germany
Solae, LLC

Completed

A Study on the Effects of Soy Protein on Blood Lipids in Men and Women With Mild to Moderate Hypercholesterolemia (PRV-08009)

Hypercholesterolemia

United States
Takeda

Completed

Efficacy and Safety of Lapaquistat Acetate Coadministered With Atorvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia
Takeda

Completed

Efficacy of Lapaquistat Acetate and Atorvastatin on Blood Cholesterol Levels in Subjects With Primary Hypercholesterolemia

Hypercholesterolemia

United States
Takeda

Terminated

Efficacy of Lapaquistat Acetate in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States
Takeda

Completed

Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States, Canada
AstraZeneca

Completed

Real-life EValuation Of High Dose RosUvastatin in High Risk Patients After TitraTION (REVORUTION)

Hypercholesterolemia

Korea, Republic of
Santaris Pharma A/S

Completed

Multiple Ascending Dose Study of SPC4955 in Healthy Subjects

Hypercholesterolemia

Germany
Afexa Life Sciences Inc

Completed

LIP-01 in Hypercholesterolemia

Hypercholesterolemia

Canada, United States
University of Manitoba

Completed

Efficacy of Plant Sterol-Fortified Dairy Product on Plasma Lipid and Plant Sterol Concentrations in Humans

Hypercholesterolemia

Canada
University of Ioannina

Completed

Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL)

Hypercholesterolemia

Greece
Gerencia de Atención Primaria, Albacete
Fundación para la Investigación Sanitaria en Castilla-La Mancha (FISCAM); Castilla-La...

Unknown

Effect of Plant Sterols on the Lipid Profile of Patients With Hypercholesterolaemia

Hypercholesterolemia
Radiant Research

Completed

Ezetimibe Reverse Cholesterol Transport (RCT) Pilot Study

Hypercholesterolemia

United States
Iowa State University
Archer Daniels Midland Co.

Completed

Flax Lignans and Heart Health (ISULignan)

Hypercholesterolemia

United States
AstraZeneca

Completed

Centralized Pan-Asian Survey on the Under Treatment of Hypercholesterolemia (CEPHEUS)

Hypercholesterolemia

Korea, Republic of, Vietnam, Malaysia, Taiwan, Philippines, China, Indonesia, Thailand
Utrecht Institute for Pharmaceutical Sciences
Harvard University; Scientific Institute for Dutch Pharmacists, The Netherlands and other collaborators

Completed

A Community Pharmacist-led Intervention to Improve Adherence to Lipid-lowering Treatment

Hypercholesterolemia

Netherlands
Bronx VA Medical Center

Unknown

Tolerability and Lipid Lowering Effect of Weekly/Biweekly Crestor in Statin Intolerant Patients Treated With Zetia

Hypercholesterolemia

United States
Hellenic Atherosclerosis Society
Minerva SA

Completed

Effect of Plant Stanol Ester-Containing Spread on Estimated Cardiovascular Risk in Comparison to Mediterranean Diet

Hypercholesterolemia

Greece
University Hospital, Bonn

Completed

Influence of Simvastatin on Apolipoprotein B-100 (apoB-100) Secretion (SVS)

Hypercholesterolemia

Germany
AstraZeneca

Completed

Rosuvastatin ORBITAL Germany

Hypercholesterolemia
The George Institute
Pfizer; Royal Prince Alfred Hospital, Sydney, Australia; Lipid and Cardiovascular... and other collaborators

Completed

Study to Assess if Internet-Based Tailored Advice Could Modify Behaviour to Improve Health

Hypercholesterolemia

Australia
Sanofi

Completed

A Study Evaluating the Safety and Efficacy of AVE5530 (4 Weeks) in Patients With Mild to Moderate Hypercholesterolemia

Hypercholesterolemia

Russian Federation, Turkey, Mexico, Hungary, Korea, Republic of, Chile
University of Utah
Unicity International

Completed

The Effect of BiosLife on Serum Lipids

Hypercholesterolemia

United States
AstraZeneca

Completed

DISCOVERY Asia - Crestor in Type IIa and IIb Hypercholesteremia

Hypercholesterolemia

China, Taiwan, Malaysia, Hong Kong, Korea, Republic of, Thailand
AstraZeneca

Completed

Pan-European Survey on the Under Treatment of Hypercholesterolemia (CEPHEUS)

Hypercholesterolemia
National Center for Complementary and Integrative...

Completed

Antioxidant Functions of Lipoic Acid

Hypercholesterolemia

United States
OBEcure Ltd.

Terminated

A Randomized, Double-Blind, Placebo-Controlled Study to Examine the Effect of Betahistine on Plasma Lipids in Patients Treated With Simvastatin

Hypercholesterolemia

Israel
University of Alabama at Birmingham
SmartFoods, Inc.

Completed

Effects of Various Higher Fat and Lower Fat Snacks on Cardiovascular Risk Factors in Men and Women.

Hypercholesterolemia
Fondazione SISA (Societa Italiana per lo Studio...

Recruiting

Lipid Transport Disorder Italian Genetic Record (LIPIGEN) (LIPIGEN)

Familial Hypercholesterolemia | Genetic Disorder

Italy
Novartis Pharmaceuticals

Recruiting

Specified Drug-use Survey of Leqvio for s.c. Injection.

Hypercholesterolaemia | Familial Hypercholesterolaemia

Japan
Imperial College London

Recruiting

EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

Familial Hypercholesterolemia

United Kingdom
University Hospital, Linkoeping

Recruiting

Clinical Decision Support for Familial Hypercholesterolemia (CDS-FH)

Hypercholesterolemia, Familial | Clinical Decision Support

Sweden
Amryt Pharma

Active, not recruiting

Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)

Homozygous Familial Hypercholesterolaemia (HoFH)

Germany, Israel, Italy, Saudi Arabia, Spain, Tunisia
Fundación Hipercolesterolemia Familiar

Completed

Alirocumab and Plaque Burden In Familial Hypercholesterolaemia (ARCHITECT)

Familial Hypercholesterolemia

Spain
Listen Trial Group

Completed

LIpid Lowering With Highly Potent Statins in Hyperlipidaemia With Type 2 Diabetes patiENts (LISTEN)

Hypercholesterolemia With Concomitant Type 2 Diabetes

Japan
University of California, Los Angeles
Olive View-UCLA Education & Research Institute

Not yet recruiting

Cardiovascular Risk Reduction in Epilepsy

Epilepsy | Hypertension | Hyperlipidemia (E.G., Hypercholesterolemia)
Sanofi
Regeneron Pharmaceuticals

Completed

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Hypercholesterolaemia

Czechia, France, Denmark, Netherlands, Austria, Mexico, Spain, United States, Argentina, Brazil, Bulgaria, Canada, Finland, Hungary, Italy, Lebanon, Norway, Poland, Russian Federation, Slovenia, South Africa, Sweden, Taiwan, Turkey
Ionis Pharmaceuticals, Inc.
Akcea Therapeutics

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial Hypercholesterolemia

Hypertriglyceridemia | Familial Hypercholesterolemia

Canada
Sanofi
Regeneron Pharmaceuticals

Completed

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (ODYSSEY KIDS)

Hypercholesterolaemia

Norway, Russian Federation, Sweden, South Africa, Czechia, United States, Canada, France, Netherlands, Spain
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia (ODYSSEY HIGH FH)

Hypercholesterolaemia

Netherlands, United States, Canada, Russian Federation, South Africa
University of Oslo
Oslo University Hospital; Mills DA

Completed

Postprandial Response After Intake of Meals With Different Fatty Acid Composition

Healthy | Familial Hypercholesterolemia

Norway
Federico II University

Completed

Efficacy of a New Symbiotic Formulation in Children With Familial Hypercholesterolemia

Dyslipidemia | Familial Hypercholesterolemia

Clinical Trials on Hypercholesterinemia

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