Clinical Trials on Hypertension,

Total 11027 results

Heart Center Leipzig - University Hospital

Completed

Arterial Stiffness as a Predictor of Response to Renal Sympathetic Denervation (EFFECTIVENES)

Therapy Resistant Arterial Hypertension

Germany
Forest Laboratories

Completed

Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension

Stage 2 Hypertension | Stage 1 Hypertension

United States
AOP Orphan Pharmaceuticals AG

Not yet recruiting

Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAH

Pulmonary Arterial Hypertension

Spain, Austria, France, Hungary
Shape Medical Systems, Inc.
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Assessing the Utility of Submaximal CPET in Treatment Management of PAH

Pulmonary Arterial Hypertension

United States
Pulmonary Hypertension Association, Inc.
University of Washington, the Collaborative Health Studies Coordinating Center

Recruiting

Pulmonary Hypertension Association Registry (PHAR)

Pulmonary Arterial Hypertension | Pulmonary Hypertension | Chronic Thromboembolic Pulmonary Hypertension

United States
Laval University
Canadian Institutes of Health Research (CIHR); AstraZeneca

Recruiting

Olaparib for PAH: a Multicenter Clinical Trial (OPTION)

Pulmonary Arterial Hypertension

Canada
Stanford University
PHaware

Active, not recruiting

Utility of At-home Monitoring of Exercise Capacity by App-based 6-minute Walk Test (DynAMITE)

Pulmonary Arterial Hypertension

United States
Cereno Scientific AB
Abbott; Worldwide Clinical Trials

Available

Safety and Efficacy of Continued CS1 Treatment of Patients With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Sweden
Actelion

Completed

FUTURE 3 Study Extension (FUTURE 3 Ext)

Pulmonary Arterial Hypertension

United States, Australia, Belarus, China, Czechia, France, Germany, Hungary, India, Israel, Italy, Mexico, Poland, Russian Federation, Serbia, South Africa, Spain, Ukraine
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Long Term Extension Study Evaluating Safety Of Sildenafil Citrate When Used To Treat Pulmonary Arterial Hypertension (PAH) In Children

Pulmonary Arterial Hypertension

United States, Colombia, Russian Federation, Taiwan, Guatemala, India, Mexico, Japan, Italy, Brazil, Hungary, Poland, Malaysia, Sweden, Chile
Laval University

Terminated

Olaparib for PAH: a Pilot Study (OPTION-p)

Pulmonary Arterial Hypertension

Canada
Heidelberg University

Completed

Effect of Pharmacologic Interaction Between ERAs and PDE-5 Inhibitors on Medication Serum Levels and Clinical Disease Status in Patients With PAH (EPIC)

Pulmonary Arterial Hypertension

Germany
Actelion

Completed

Extension of the Psychometric Validation Study ORCHESTRA in Patients With PAH

Pulmonary Arterial Hypertension

Spain, France, Italy
University of Arizona

Unknown

Trial to Evaluate Parenteral Treprostinil and Riociguat on Right Ventriculo-vascular Coupling and Morphology in Those With Advanced PAH

Pulmonary Arterial Hypertension

United States
RenJi Hospital

Unknown

Long-term Outcomes of Pregnant Women With PAH

Pulmonary Arterial Hypertension

China
Pfizer

Terminated

Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term Safety

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Romania, Ukraine
Actelion

Terminated

Clinical Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT Instrument (SYMPHONYext)

Pulmonary Arterial Hypertension

United States
United Therapeutics

Completed

Safety and Tolerability of Rapid Dose Titration of Subcutaneous Remodulin® Therapy in PAH Subjects (RAPID) (RAPID)

Pulmonary Arterial Hypertension
Amsterdam UMC, location VUmc

Unknown

Goal Oriented Strategy to Preserve Ejection Fraction Trial (GOSPEL)

Pulmonary Arterial Hypertension

Netherlands
University of Arizona
United Therapeutics

Completed

Study Of Right Ventricular Performance In PAH Patients Treated With Rapid Dose Treprostinil (Remodulin) (ISS)

Pulmonary Arterial Hypertension

United States
United Therapeutics

Completed

Remodulin® to Oral Treprostinil Transition

Pulmonary Arterial Hypertension

United States
Mayo Clinic

Completed

Early Detection of Pulmonary Arterial Hypertension Using Cardiac Magnetic Resonance Imaging

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States
Actelion

Terminated

Ventavis® Registry Protocol (RESPIRE)

Pulmonary Arterial Hypertension

United States
Nantes University Hospital

Withdrawn

Evaluation of Metformin Activity in Addition to Conventional Treatment of Grade II or III Pulmonary Arterial Hypertension (PAH) (MetHTAP)

Pulmonary Arterial Hypertension

France
Mayo Clinic

Completed

Modulating Effects of Lisinopril on Sildenafil Activity in Pulmonary Arterial Hypertension(PAH)( MELISSA) (MELISSA)

Pulmonary Arterial Hypertension

United States
Rabin Medical Center

Unknown

Rehabilitation for Patients With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Israel
Bastiaan Driehuys
Regeneron Pharmaceuticals

Withdrawn

Xenon MRI in Stable Pulmonary Hypertension (Jupiter AUGEAN)

Pulmonary Artery Hypertension
University of Colorado, Denver
Children's Hospital Colorado; Food and Drug Administration (FDA)

Completed

Observational Study of Actigraphy in Pediatric Pulmonary Arterial Hypertension

Hypertension;Pulmonary;Primary

United States
Indonesia University

Completed

The Role of Trimetazidine on Right Ventricle Function in Pulmonary Arterial Hypertension (TRIMETA-PH)

Precapillary Pulmonary Hypertension

Indonesia
E-Star BioTech, LLC
Mayo Clinic; Integrium

Completed

Safety And Tolerability Of Subcutaneous MANP In Difficult To Control/Resistant Hypertensive Subjects (DTC/RHS)

Resistant Hypertension | Difficult to Control Hypertension

United States
Radboud University Medical Center

Completed

Nijmegen Antihypertensive Management Improvement Study (NAMIS)

Primary Hypertension

Netherlands
Anil Nigam

Unknown

Effect of High-Intensity Interval Training Compared to Hydrochlorothiazide on Ambulatory Blood Pressure (DIISCCO)

Hypertension,Essential | Exercise Activity

Canada
Regional Hospital Holstebro

Completed

Heart Rate Variability in White Coat Hypertension and Essential Hypertension

Healthy | White Coat Hypertension | Essential Hypertension

Denmark
International Centre for Diarrhoeal Disease Research...
Bill and Melinda Gates Foundation; Salu Design Group

Recruiting

Optimizing Gestational Weight Gain, Birth Weight and Other Perinatal Outcomes Among Pregnant Women at Risk of Hypertension in Pregnancy

Hypertension, Pregnancy-Induced | Hypertension in Pregnancy | Hypertension, Essential Hypertension | Hypertension; Pre-Eclampsia

Bangladesh
Vanderbilt University Medical Center

Recruiting

Hormonal, Metabolic, and Signaling Interactions in PAH

Idiopathic Pulmonary Arterial Hypertension | Heritable Pulmonary Arterial Hypertension | Scleroderma Associated Pulmonary Arterial Hypertension | Appetite Suppressant Associate PAH

United States
China National Center for Cardiovascular Diseases

Recruiting

Combined Use of Radiofrequency-ablation and Balloon-septostomy in the Creation of a Stable Inter-atrial Communication (CURB)

Pulmonary Arterial Hypertension

China
Bayer
Xcenda, LLC

Active, not recruiting

A Study to Learn About How Well Riociguat Works, How Safe it is and How it is Used Under Real World Conditions in Patients in the United States Who Are Receiving Riociguat for High Blood Pressure in the Arteries That Carry Blood From the Heart to the Lungs (Pulmonary Arterial Hypertension, PAH) (ROAR)

Pulmonary Arterial Hypertension

United States, Puerto Rico
United Therapeutics

Active, not recruiting

Evaluate Real-World Use of Next Generation Infusion Pumps to Administer Remodulin (EVOLVE)

Pulmonary Arterial Hypertension

United States
Merck Sharp & Dohme LLC

Completed

A Study of Single Doses of MK -5475 on Pulmonary Vascular Resistance (MK-5475-002)

Pulmonary Arterial Hypertension

Moldova, Republic of
PhaseBio Pharmaceuticals Inc.

Terminated

Phase 2 Study to Assess Safety, Tolerability and Efficacy of Once Weekly SC Pemziviptadil (PB1046) in Subjects With Symptomatic PAH (VIP)

Pulmonary Arterial Hypertension

United States
University of Pittsburgh

Withdrawn

miRNA and Myokines in Patients With PAH

Pulmonary Arterial Hypertension

United States
Bayer

Completed

Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy (REPLACE)

Pulmonary Arterial Hypertension

Belgium, France, Spain, Portugal, Turkey, United States, Germany, Korea, Republic of, Mexico, Austria, Canada, Denmark, Poland, Italy, Greece, Taiwan, Czechia, Netherlands, Japan, Brazil, United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)
The Cleveland Clinic

Withdrawn

Hydroxyurea in Pulmonary Arterial Hypertension

Pulmonary Hypertension
PhaseBio Pharmaceuticals Inc.

Completed

A Study to Assess the Safety, Tolerability, and Hemodynamic Response of PB1046 in Subjects With PAH

Pulmonary Arterial Hypertension

United States
National Health Service, United Kingdom

Completed

The Effect of Adding Exercise Training to Optimal Therapy in PAH

Pulmonary Arterial Hypertension

United Kingdom
Medical University of Bialystok

Completed

PET/MRI in PAH Patients

Pulmonary Arterial Hypertension
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Right Ventricular Pulmonary Vascular Interaction in Pulmonary Hypertension

Pulmonary Arterial Hypertension (PAH)
United Therapeutics

Terminated

Safety Study of PLX-PAD Cells to Treat Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

Australia
Pfizer

Terminated

Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Bulgaria, Argentina, Chile, China, Colombia, Czech Republic, India, Malaysia, Mexico, Peru, Romania, Russian Federation, Serbia, South Africa, Thailand, Turkey, Ukraine
Actelion

Completed

Combination Therapy in Pulmonary Arterial Hypertension (COMPASS 3)

Pulmonary Arterial Hypertension

United States

Clinical Trials on Hypertension,

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