Clinical Trials on Hypervitaminosis A

Total 4860 results

Safaa AA Khaled

Unknown

Viral Hepatitis B and C Infection in Patients With Idiopathic Thrombocytopenic Purpura Treated With Triple Therapy

Viral Hepatitis | ITP - Immune Thrombocytopenic Purpura
First Affiliated Hospital Xi'an Jiaotong University
Xi'an Gaoxin Hospital

Unknown

Effects of Fat-soluble Vitamins Supplementation on Common Complications and Neural Development in Very Low Birth Weight Infants

Sepsis | Anemia | Vitamin D Deficiency | Vitamin A Deficiency | Bronchopulmonary Dysplasia | Very Low Birth Weight Infants | Vitamin E Deficiency

China
AbbVie

Completed

Ombitasvir/ABT-450/Ritonavir and Dasabuvir With or Without Ribavirin in HCV Genotype 1-Infected Adults With Chronic Kidney Disease

Chronic Hepatitis C | Hepatitis C Virus | Severe Renal Impairment | Compensated Cirrhosis | End-stage Renal Disease
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB PRP~T Combined Vaccine in Filipino Infants

Hepatitis B | Pertussis | Tetanus | Diphtheria | Influenza

Philippines
Valme University Hospital
Hospital Universitario Virgen Macarena; Hospital Universitario Reina Sofia... and other collaborators

Completed

Hepatic Safety of Currently Used Antiretroviral Regimens in Patients With Chronic Hepatitis Under Real Life Conditions

Hepatitis C, Chronic | Hepatitis B, Chronic | Human Immunodeficiency Virus

Spain
Shaare Zedek Medical Center

Unknown

Examining the Immune Response in Patients With Gaucher Disease and Hepatitis C

Hepatitis C | Gaucher Disease

Israel
Peregrine Pharmaceuticals

Completed

Bavituximab Repeat-Dose Trial in Patients Co-Infected With Chronic Hepatitis C Virus and Human Immunodeficiency Virus

Hepatitis C Virus | Hiv Infections

United States
Actelion

Completed

Miglustat in Niemann-Pick Type C Disease

Niemann-Pick Type C Disease

United States
PT Bio Farma
Hasan Sadikin General Hospital

Not yet recruiting

Immunogenicity and Safety of DTP-HB-Hib Using New Hepatitis B Bulk (Bio Farma)

Diphtheria Vaccine Adverse Reaction | Tetanus Vaccine Adverse Reaction | Pertussis Vaccine Adverse Reaction | Haemophilus Influenzae Type B Vaccine Adverse Reaction | Hepatitis B Vaccine Adverse Reaction

Indonesia
Medical University of Warsaw

Recruiting

Possible Differences in HCC Course Depending on DAA Treatment

Liver Cirrhosis | Carcinoma, Hepatocellular | Hepatitis C, Chronic | Drug Effect | Hepatitis C Virus Infection, Response to Therapy of | Drug Side Effect

Poland
National Institutes of Health Clinical Center (CC)
Washington D.C. Veterans Affairs Medical Center

Completed

Long-Term Study of Liver Disease in People With Hepatitis B and/or Hepatitis C With or Without HIV Infection

Hepatitis B | Hepatitis C | HIV-HCV Co-Infection

United States
Genzyme, a Sanofi Company

Completed

Efficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency (ASCEND)

Sphingomyelin Lipidosis

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Chile, France, Germany, Italy, Japan, Netherlands, Portugal, Spain, Tunisia, Turkey, United Kingdom
Alexion Pharmaceuticals
Portola Pharmaceuticals

Completed

Phase 1/2a Dose Escalation Study in Participants With CLL, SLL, or NHL

Follicular Lymphoma (FL/Indolent NHL) | Aggressive NHL (a NHL) | Chronic Lymphocytic Leukemia (CLL) / Small Lymphocytic Lymphoma (SLL) | T-cell Lymphoma (PTCL and CTCL) | B-cell Non Hodgkin Lymphoma (NHL)

United States
AbbVie

Completed

A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced, Non-Cirrhotic Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With or Without Human Immunodeficiency Virus Co-Infection (VOYAGE-1)

Hepatitis C Virus (HCV)

China, Korea, Republic of, Singapore
Biocad

Completed

An Open-label Randomized Multicenter Phase III Clinical Study Comparing Safety and Efficacy of Algeron (Cepeginterferon Alfa-2b) and and PegIntron (Peginterferon Alfa-2b) in Combination With Ribavirin as Combined Treatment of Chronic Hepatitis C in Human Immunodeficiency Virus-1 Infected Patients

Hepatitis | Hepatitis C | Hepatitis C/ Human Immunodeficiency Virus Coinfection

Russian Federation
Genzyme, a Sanofi Company

Completed

Tolerability and Safety Study of Recombinant Human Acid Sphingomyelinase in Acid Sphingomyelinase Deficiency Patients

Human Acid Sphingomyelinase Deficiency

United Kingdom, United States
Henry Ford Health System
Schering-Plough

Completed

Association Between Hepatitis C Infection and Renal Cell Carcinoma

Renal Cell Carcinoma | Hepatitis C | Colorectal Cancer

United States
Sanofi Pasteur, a Sanofi Company
Merck Sharp & Dohme LLC

Completed

Study of PR5I, a Pediatric Combination Vaccine With Enhanced Hepatitis B Component Given Concomitantly With Prevnar®

Hepatitis B | Pertussis | Tetanus | Diphtheria | Polio

Canada
Chung-Hsing Wang
Sanofi

Not yet recruiting

Screening for Gaucher Disease and Acid Sphingomyelinase Deficiency

Gaucher Disease

Taiwan
Sanofi

Recruiting

Data Analysis of Adult and Pediatric Participants With Acid Sphingomyelinase Deficiency (ASMD) on Early Access to Olipudase Alfa in France (OPERA)

Acid Sphingomyelinase Deficiency (ASMD)

France
Rocket Pharmaceuticals Inc.

Active, not recruiting

Lentiviral-mediated Gene Therapy for Pediatric Patients With Fanconi Anemia Subtype A

Fanconi Anemia Complementation Group A

Spain, United Kingdom
Rocket Pharmaceuticals Inc.

Active, not recruiting

Gene Therapy for Fanconi Anemia, Complementation Group A

Fanconi Anemia Complementation Group A

United States
Sanofi

Completed

A Prospective and Retrospective Cohort Study in Patients With Chronic Forms of Acid Sphingomyelinase Deficiency (ASMD)

Sphingomyelin Lipidosis

Italy, Czechia, Belgium, France, Portugal, Turkey, United States, Argentina, Brazil, Chile, Germany, Romania, Spain
Rennes University Hospital
Ministry of Health, France

Completed

Quantification of Liver Iron Overload and Steatosis Using Magnetic Resonance Imaging (SURFER)

Hepatitis B | Hepatitis C | Iron Overload | Metabolic Syndrome X | Alcohol Abuse

France, Spain
Great Ormond Street Hospital for Children NHS Foundation...

Completed

Prevalence of Autistic Spectrum Disorder (ASD) in Children With Haemophilia

Autism Spectrum Disorder | Attention Deficit Hyperactivity Disorder | Social Communication Disorder | Haemophilia
Kobe University
Boehringer Ingelheim

Active, not recruiting

A Extension Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance ( EMPIRE-02 ) (EMPIRE-02)

Insulin Resistance - Type A | Insulin Resistance - Type B | Lipoatrophic Diabetes Mellitus | Insulin Resistance Syndrome

Japan
Parc Sanitari Pere Virgili
Althaia Xarxa Assistencial Universitària de Manresa; Hospital Vall d'Hebron; Consorci... and other collaborators

Completed

Diabetes as an Accelerator of Cognitive Impairment and Alzheimer's Disease (DIALCAT)

Patients Aged 65-85 (Both Included) | Diagnosed of Mild Cognitive Impairment | Diagnosed of Type 2 Diabetes in Active Treatment (Hypoglycemic Agents) for a Period ≥5 Years

Spain
Johns Hopkins University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

CHAMPS Study: Chronic HepAtitis C Management to ImProve OutcomeS (CHAMPS)

Human Immunodeficiency Virus | Hepatitis C Virus Infection, Response to Therapy of

United States
Gilead Sciences

Completed

Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed-Dose Combination (FDC) for 6 Weeks in Adults With Acute Genotype 1 or 4 Hepatitis C Virus (HCV) and Chronic Human Immunodeficiency Virus (HIV)-1 Co-Infection

Hepatitis C Infection With HIV Co-Infection

United Kingdom, Germany
University of Arkansas
University of Toronto; University of North Carolina, Chapel Hill; University...

Withdrawn

The Regression of Liver Fibrosis and Risk for Hepatocellular Carcinoma (ROLFH) Study (ROLFH)

Chronic Hepatitis B | Chronic Hepatitis C

United States, Canada
Aarhus University Hospital

Completed

Study of Cerebral Function in Patients With Chronic Hepatitis C Infection (HCV/CNS)

Hepatitis C, Chronic | Cognition Disorders | Major Depressive Disorder | Fatigue Syndrome, Chronic

Denmark
AstraZeneca

Terminated

A Phase I Study of AZD1480 in Patients With Advanced Solid Malignancies and Advanced Hepatocellular Carcinoma in the Escalation Phase,Non-Small Cell Lung Cancer(NSCLC) and Non-smokers With Lung Metastasis and Gastric Cancer and Solid Tumour in the Expansion Phase.

Gastric Cancer | Advanced Solid Malignancies | Solid Tumour | Child-Pugh A to B7 Advanced Hepatocellular Carcinoma | EGFR and/or ROS Mutant NSCLC | Lung Metastasis Carcinoma

Korea, Republic of
National Taiwan University Hospital

Recruiting

HCV Reinfection in in HIV/HCV-coinfected Patients Achieving SVR by Antiviral Therapy

Hepatitis C Virus Infection | Hepatitis C Virus Infection, Response to Therapy of | Human Immunodeficiency Virus (HIV) Coinfection

Taiwan
Sangamo Therapeutics

Active, not recruiting

Long Term Follow-up (LTFU) of Subjects Who Received SB-318, SB-913, or SB-FIX (LTFU)

Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II

United States
Sanofi

Approved for marketing

Compassionate Use Program for Olipudase Alfa Enzyme Replacement Therapy for Patients With Chronic Acid Sphingomyelinase Deficiency (ASMD)

Sphingomyelin Lipidosis
Bristol-Myers Squibb

Completed

Pharmacokinetic Study of BMS-914143 in Participants With Normal Renal Function and Mild, Moderate, Severe and End-stage Renal Dysfunction (PK)

Chronic Hepatitis C Virus Infection | Chronic Hepatitis B Virus Infection

United States
Eline C. B. Eskes

Recruiting

Magnetic Resonance Spectroscopy in Acid Sphingomyelinase Deficiency (MONACO)

Asmd, Visceral Type

Netherlands
Ruijin Hospital

Recruiting

Digitalized Surveillance Management for Liver Cancer Risk Population in Improving Eearly Diagnosis Efficancy in Chinese Population (dSEARCH) (dSEARCH)

Carcinoma, Hepatocellular | Hepatitis C, Chronic | Hepatitis B, Chronic | Cirrhosis, Liver | Non-Alcoholic Fatty Liver Disease

China
National Cancer Institute (NCI)

Active, not recruiting

Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors

Cirrhosis | Hepatitis B Infection | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | Recurrent Hepatocellular Carcinoma | Refractory Malignant Neoplasm | Hepatitis C Infection | Stage IV Hepatocellular Carcinoma AJCC v7

United States
Genzyme, a Sanofi Company

Completed

A Long-Term Study of Olipudase Alfa in Patients With Acid Sphingomyelinase Deficiency

Sphingomyelin Lipidosis

United States, Belgium, Brazil, France, Germany, Italy, United Kingdom
University of Southern California
National Institute on Aging (NIA); Huntington Hospital

Completed

Social Work Intervention Focused on Transitions (SWIFT)

Depression | Stroke | Hypertension | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Asthma | Chronic Heart Failure | Heart Disease | Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention

United States
Yonsei University

Unknown

Clinical Trials to Compare the Effects of Pioglitazone and Evogliptin on Hepatic Fibrosis in Patients With Chronic Hepatitis B With Significant Hepatic Fibrosis With Type 2 Diabetes

Chronic Hepatitis B With Significant Hepatic Fibrosis With Type 2 Diabetes

Korea, Republic of
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Retrovirus Epidemiology Donor Study-II (REDS-II)

HIV Infections | Acquired Immunodeficiency Syndrome | Retroviridae Infections | Hepatitis B | Hepatitis, Viral, Human | Blood Transfusion | HIV-1 | Blood Donors | Hepacivirus | HIV-2 | HTLV-I | HTLV-II | West Nile Virus
National Institute of Diabetes and Digestive and...

Completed

Lamivudine for Chronic Hepatitis B

Chronic Hepatitis B | Glomerulonephritis | Polyarteritis Nodosa | Chronic Hepatitis D

United States
NextCell Pharma Ab
Karolinska Trial Alliance

Recruiting

Treatment of Respiratory Complications Associated With COVID19,Influenza ,Metapneumovirus,RSV Infection Using ProTrans®

Influenza A | Respiratory Syncytial Virus (RSV) | COVID-19 Acute Respiratory Distress Syndrome | Metapneumovirus Pneumonia

Sweden
Sanofi

Recruiting

A Non-Interventional National Study in Pediatric Patients With Unexplained Enlarged Spleen (OPPUS)

Acid SphingoMyelinase Deficiency | Gaucher Disease, Splenomegaly

France
Institut de Recherche pour le Developpement
Expertise France-L'Initiative; French National Research Institute for Sustainable...

Recruiting

User-friendly HIV Testing and Counseling Services

HIV Infections | Hepatitis C | Hepatitis B, Chronic | Sexually Transmitted Infection

Thailand
AbbVie

Completed

Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With Compensated Cirrhosis and With or Without Human Immunodeficiency Virus Co-Infection (VOYAGE-2)

Hepatitis C Virus (HCV)

China, Korea, Republic of
Actelion

Completed

Safety and Efficacy of Miglustat in Chinese NPC Patients

Niemann-Pick Disease, Type C

China
AbbVie

Completed

A Study to Evaluate the Efficacy and Safety of Experimental Drugs ABT- 493/ABT-530 in Adults With Chronic Hepatitis C Virus Genotype 1-6 Infection and Human Immunodeficiency Virus -1 Coinfection (EXPEDITION-2) (EXPEDITION-2)

Hepatitis C Virus Infection | Chronic Hepatitis C | Human Immunodeficiency Virus Infection | Compensated Cirrhosis and Non-cirrhotics

Clinical Trials on Hypervitaminosis A

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