Clinical Trials on Hypothalamic-pituitary Lesions in Belgium

Total 75 results

Universitaire Ziekenhuizen KU Leuven
University Hospital, Ghent; Gasthuis Zusters Antwerpen

Recruiting

Neurocognition After Radiotherapy in CNS- and Skull-base Tumors (NARCiS)

Glioma | Pituitary Adenoma | Brain Tumor | Magnetic Resonance Imaging | Meningioma | Cognition

Belgium
RECORDATI GROUP

Recruiting

Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Disease

Cushing's Disease

Belgium, France, Italy, Bulgaria, Slovenia, United Kingdom
Universitair Ziekenhuis Brussel

Unknown

An Assessment of the Occurrence of Hormone Deficiency in Patients With Empty Sella

Empty Sella

Belgium
University Hospital, Ghent
Pfizer

Completed

Growth Hormone, IGF-1 and Medical Treatment in Acromegaly: Are There Effects on Gut Hormone Physiology and Postprandial Substrate Metabolism?

Acromegaly

Belgium
Hasselt University
CHU de Charleroi; Erasme hospital

Recruiting

Effect of Variance on Error Correction During Coupling (Cerrebellar Lesions)

Cerebellar Lesions

Belgium
Pfizer

Terminated

A Single Dose Study to Evaluate the PK-PD Response and Safety of PHA-794428 in Children With Growth Hormone Deficiency

Growth Hormone Deficiency

France, Belgium, Germany, Israel, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety Evaluation of Osilodrostat in Cushing's Disease (LINC-4)

Cushing's Disease

United States, China, Canada, Belgium, Thailand, Spain, Turkey, Brazil, Portugal, Russian Federation, Poland, Greece, Costa Rica, Switzerland
Novartis Pharmaceuticals

Terminated

Study of the Efficacy and Safety of Pasireotide s.c. +/- Cabergoline in Patients With Cushing's Disease

Cushings Disease

Italy, Belgium, India, Netherlands, Argentina, Germany, Turkey, Brazil, Spain, Hungary, Malaysia, Mexico, Greece, United States, Colombia, France
Ipsen

Terminated

Assessment of BIM23B065, Given as Repeated Subcutaneous Injection in Subjects With Acromegaly (DOPAACRO 002)

Acromegaly

Serbia, Belgium, Hungary, Ukraine
Universitaire Ziekenhuizen KU Leuven

Active, not recruiting

Prospective Interventional Clinical Trial of an MRI Based Patient Specific Focal Knee Resurfacing Implant (Episealer)

Focal Cartilage Lesions

Belgium
Universitaire Ziekenhuizen KU Leuven
Biosensors International

Unknown

COmplex BifuRcation Lesions: a Comparison Between the AXXESS Device and Culotte Stenting: an Optical Coherence Tomography (OCT) Study (COBRA)

True Coronary Bifurcation Lesions

Belgium
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Different Dose Levels of Pasireotide in Patients With de Novo, Persistent or Recurrent Cushing's Disease

Cushing's Disease

United States, Canada, Italy, Belgium, Turkey, Spain, France, Denmark, Germany, Greece, Israel, Argentina, China, Portugal, Brazil, Mexico, Finland, Poland
Flanders Medical Research Program

Completed

Misago Iliac Study (MISAGO ILIAC)

Vascular Lesions

Germany, Belgium
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Pasireotide Administered Monthly in Patients With Cushing's Disease

Cushing's Disease

Italy, Belgium, Japan, Germany, United Kingdom, Thailand, Spain, France, Netherlands, Turkey, Israel, China, United States, Canada, India, Argentina, Brazil, Peru, Poland, Russian Federation
Novartis Pharmaceuticals

Completed

An Extension Study to Assess the Long-Term Safety and Efficacy of Pasireotide in Participants With Acromegaly

Acromegaly

Italy, Australia, Belgium, Germany, Switzerland, United States, France
Novartis Pharmaceuticals

Completed

Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or Acromegaly

Acromegaly | Cushing's Disease

United States, Turkey, Belgium, Thailand, Germany, Denmark, Russian Federation, Peru, China, Brazil, India, Poland
Ipsen

Completed

Lanreotide as Primary Treatment for Acromegalic Patients With Pituitary Gland Macroadenoma (PRIMARYS)

Acromegaly

Netherlands, Germany, France, United Kingdom, Turkey, Belgium, Czechia, Finland, Italy
Guerbet

Completed

Pharmacokinetics, Pharmacodynamics Profile and Tolerance of P03277 in Healthy Subjects and Patients With Brain Lesions

Healthy Volunteers | Brain Lesion

Belgium
Ipsen

Completed

A Study to Evaluate the Risk of Developing a Heart Condition Called Valvular Regurgitation in Patients With Acromegaly Treated With Either Lanreotide or Octreotide

Acromegaly

Spain, United Kingdom, Italy, France, Belgium, Hungary, Czechia, Denmark, Poland, Sweden
Ipsen

Terminated

Study to Assess the Efficacy and Safety of Repeated Administration of BIM 23A760 in Patients With Acromegaly (TULIPIA)

Acromegaly

Belgium, Brazil, Lithuania, Sweden, France, United States, Czechia, Latvia, Mexico, Netherlands, Poland, Romania, Ukraine
Maatschap Cardiologie Zwolle
Terumo Europe N.V.

Completed

Complex Large-bore Radial Percutaneous Coronary Intervention (PCI) Trial (Color)

Complex Coronary Lesions

Netherlands, Belgium, Germany, Switzerland, United Kingdom
Centre Hospitalier Universitaire Saint Pierre

Terminated

EBUS-Miniprobes Sampling for Peripheral Lung Lesions

Lung Cancer | Peripheral Pulmonary Lesions

Belgium
Pfizer

Terminated

A Study To Evaluate The Dose Response And Safety Of PHA-794428 In Adults With Growth Hormone Deficiency

Growth Hormone Deficiency

Germany, Italy, Spain, Denmark, Czech Republic, Belgium, United Kingdom, Netherlands, Poland, Slovakia, Sweden, France
Ipsen

Completed

Validation Study of the SAGIT® Instrument in Acromegaly (SAGIT)

Acromegaly

United States, United Kingdom, Italy, Netherlands, France, Belgium, Brazil, Denmark, Germany, Spain
Catholic University of the Sacred Heart
University of Amsterdam; Erasme University Hospital

Completed

FV-EUS Endoscope Versus CLA-EUS for EUS-FNA of Solid Lesions

Solid Lesions of the GI Tract or of Adjacent Organs

Belgium, Italy, Netherlands
Maatschap Cardiologie Zwolle
Diagram B.V.

Completed

Ultrasound Guided Transfemoral Complex Large-bore PCI Trial (ULTRACOLOR)

Percutaneous Coronary Intervention | Complex Coronary Lesions

Netherlands, Belgium, Germany
Biotronik AG

Completed

First in Man Trial - BIOSOLVE-I (BIOSOLVE-I)

de Novo Lesions in Native Coronary Arteries

Netherlands, Switzerland, Germany, Belgium
University Hospital, Ghent

Completed

Treatment of Cartilage Lesions in Flanders Today

Lesion of Joint Capsule of Knee Region

Belgium
Novo Nordisk A/S

Completed

Effect of Growth Hormone on Bone Mineral Density in Young Adults With Child-hood Onset Growth Hormone Deficiency

Growth Hormone Disorder | Adult Growth Hormone Deficiency

Sweden, Austria, Spain, Switzerland, Germany, France, Australia, Poland, United Kingdom, Norway, Belgium, Hungary
Ipsen

Completed

Study to Determine the Maximum Tolerated Dose, Safety and Tolerability of a Single Dose of Lanreotide Prolonged Release Formulation (PRF) in Subjects With Acromegaly

Acromegaly

France, Germany, Spain, Belgium, Russian Federation, United Kingdom, Italy, Lithuania, Czechia, Romania, Poland, Netherlands
Novo Nordisk A/S

Completed

A Trial Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Dose of Long-acting Growth Hormone (Somapacitan) Compared to Daily Dosing of Norditropin® SimpleXx® in Children With Growth Hormone Deficiency

Growth Hormone Disorder | Growth Hormone Deficiency in Children

France, Israel, Austria, Spain, Switzerland, North Macedonia, Norway, Slovenia, Belgium, Sweden
Maastricht University Medical Center
King's College London; Oslo University Hospital; Jessa Hospital; University Hospital... and other collaborators

Active, not recruiting

The ORANGE II PLUS - Trial: Open Versus Laparoscopic Hemihepatectomy

Liver Lesions Requiring Hemihepatectomy

United Kingdom, Netherlands, Belgium, Italy, Norway, Germany
Crinetics Pharmaceuticals Inc.

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-1)

Acromegaly

United States, Argentina, Belgium, Brazil, Bulgaria, France, Hungary, Israel, Italy, Peru, Poland, Russian Federation, Serbia, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Pasireotide Long Acting Release (LAR) Versus Octreotide LAR or Lanreotide Autogel (ATG) in Patients With Inadequately Controlled Acromegaly (PAOLA)

Acromegaly

United States, Italy, Belgium, Saudi Arabia, Spain, France, Germany, Canada, United Kingdom, Colombia, Brazil, Israel, Turkey, Romania, Norway, Poland, Russian Federation, Argentina
Sanofi

Completed

Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

France, Germany, Belgium, Hungary
Crinetics Pharmaceuticals Inc.

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2) (PATHFNDR-2)

Acromegaly

United States, Argentina, Brazil, Bulgaria, France, Hungary, Israel, Italy, Poland, United Kingdom, China, Germany, Greece, India, Spain
Brugmann University Hospital

Completed

A Prolongation of a Clinical Study to Evaluate the Efficacy of an Aqueous Gel Containing 2% (w/w) of Cidofovir, Directly Applied on the Cervix Exhibiting High Grade Squamous Intraepithelial Lesions.

High Grade Cervical Epithelial Neoplasia (CIN2+)

Belgium
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Unknown

PREPL in Health and Disease (PHD)

Obesity | Healthy Volunteers | Prader-Willi Syndrome | Muscle Hypotonia | Hypotonia-Cystinuria Syndrome | Dwarfism, Growth Hormone Deficiency

Belgium
Mastelli S.r.l
Latis S.r.l.

Recruiting

Study of Clinical Performance and Safety of Treatments in Degenerative Meniscopathy With Injection of Polynucleotides

Meniscus Lesion | Meniscus Tear

Belgium, Italy
Prof. Dr. Raf Bisschops
3-D Matrix Europe SAS

Recruiting

Purastat Prevention Delayed Bleeding Duodenum

Lesion; Duodenum

Belgium
University Ghent
Distrac

Completed

Effectivity and Efficiency of Turning Frequencies: a Randomised Controlled Trial

Pressure Ulcer Lesions (Grade 2 or More)

Belgium
Fin-Ceramica Faenza Spa

Completed

Study for the Treatment of Knee Chondral and Osteochondral Lesions

Knee Chondral Lesion | Knee Osteochondral Lesion

Switzerland, Italy, Austria, Belgium, Germany, Norway, Poland, South Africa, Sweden
ECRI bv
Boston Scientific Corporation

Active, not recruiting

Intravascular Ultrasound Guidance for Complex High-risk Indicated Procedures (IVUS-CHIP)

Complex Coronary Lesions

Spain, United Kingdom, Netherlands, France, Belgium, Germany, Italy
RECORDATI GROUP

Completed

Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies

Prostate Cancer | Neuroendocrine Tumors | Acromegaly | Cushing's Disease | Dumping Syndrome | Pituitary Tumors | Ectopic ACTH Secreting (EAS) Tumors | Melanoma Negative for bRAF | Melanoma Negative for nRAS

Belgium, Brazil, Bulgaria, Canada, France, Germany, Italy, Japan, Korea, Republic of, Thailand, Turkey, United States, Argentina, Greece, Hungary, India, Israel, Malaysia, Mexico, Netherlands, Peru, Poland, Portugal, Romania, Russian Federation and more
Novartis Pharmaceuticals

Completed

Pasireotide in Patients With Acromegaly Inadequately Controlled With First Generation Somatostatin Analogues

Acromegaly

Italy, Belgium, United Kingdom, Bulgaria, Turkey, France, Portugal, China, Argentina, Brazil, Colombia, Hungary, Malaysia, Mexico, Romania
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Pasireotide Long Acting Release (LAR) vs. Octreotide LAR in Patients With Active Acromegaly

Acromegaly

United States, Germany, Italy, Belgium, Taiwan, Turkey, Switzerland, Israel, Netherlands, Sweden, United Kingdom, Korea, Republic of, Spain, France, Canada, Greece, Russian Federation, Denmark, Mexico, China, Hungary, Norway, Argentina and more
Novo Nordisk A/S

Recruiting

Investigating Efficacy and Safety of Once-weekly NNC0195-0092 (Somapacitan) Treatment Compared to Daily Growth Hormone Treatment (Norditropin® FlexPro®) in Growth Hormone Treatment naïve Pre-pubertal Children With Growth Hormone Deficiency

Growth Hormone Disorder | Growth Hormone Deficiency in Children

United States, Japan, Israel, India, Austria, Slovenia, Belgium, Brazil, France, Germany, Sweden, Turkey, Ukraine
Catherine Vanpachterbeke

Completed

Preventing Invasive Cervical Cancer: The Importance of Expectant Management in Young Women With High-grade Pre-cancerous Lesions

High-Grade Squamous Intraepithelial Lesions

Belgium
University Hospital, Ghent
GC Europe

Completed

A Prospective, Randomized Clinical Study on the Effects of Casein Phosphopeptide-amorphous Calcium Phosphate (CPP-ACP) Paste on Plaque, Gingivitis and White Spot Lesions in Orthodontic Patients - Part 1

Early Caries Lesions

Belgium
CellCoTec B.V.

Completed

INSTRUCT for Repair of Knee Cartilage Defects

Articular Cartilage Lesion of the Knee

Belgium, Poland, United Kingdom

Clinical Trials on Hypothalamic-pituitary Lesions in Belgium

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