Clinical Trials on IDH1-mutant Cholangiocarcinoma

Total 916 results

The First People's Hospital of Changzhou

Active, not recruiting

Radiofrquency Ablation Combined With Cytokine-induced Killer Cells for the Patients With Cholangiocarcinoma

Cholangiocarcinoma

China
University of Alabama at Birmingham
Society of Abdominal Radiology

Completed

The Role of Gadoxetate (Eovist) Enhanced CT in Evaluating Cholangiocarcinoma

Cholangiocarcinoma

United States
H. Lee Moffitt Cancer Center and Research Institute
BTG International Inc.

Completed

Study Of Intrahepatic Arterial Injection of 90-Y Glass Microspheres for Cholangiocarcinoma

Cholangiocarcinoma

United States
Vejle Hospital

Completed

Combination Chemotherapy Plus Panitumumab or Bevacizumab for Inoperable Cholangiocarcinoma Without KRAS Mutations (GOC-B-P)

Cholangiocarcinoma

Denmark
li xiong

Suspended

Safety and Efficiency of Photodynamic Therapy for Blie Duct Carcinoma

Cholangiocarcinoma

China
Technical University of Munich
Münchner Studienzentrum

Withdrawn

Gemcitabine/Oxaliplatin and Photodynamic Therapy in Cholangiocarcinoma (GemOx-PDT)

Cholangiocarcinoma

Germany
Ratchavithi Hospital

Unknown

Single Arm Study of RAD001 as Monotherapy in Treatment in Advanced Cholangiocarcinoma (CRAD001T)

Cholangiocarcinoma
Rigshospitalet, Denmark
Henrik Jensen, Dept. of Oncology, Vejle Sygehus, Vejle, Denmark

Completed

Gemcitabine, Oxaliplatin and Capecitabine in Patients With Advanced Cholangiocarcinoma

Cholangiocarcinoma

Denmark
Pierre Fabre Medicament
Pfizer; Merck KGaA, Darmstadt, Germany; Ono Pharmaceutical Co. Ltd

Completed

Encorafenib, Binimetinib and Cetuximab in Subjects With Previously Untreated BRAF-mutant ColoRectal Cancer (ANCHOR-CRC)

BRAF V600E-mutant Metastatic Colorectal Cancer

France, Italy, United States, Spain, United Kingdom, Belgium, Austria, Japan, Netherlands
Georgetown University
AstraZeneca

Recruiting

Neoadjuvant Tremelimumab and Durvalumab With Gem/Cis in Intrahepatic Cholangiocarcinoma (ESR-22-21719)

Biliary Tract Cancer | Borderline Resectable Carcinoma

United States
First People's Hospital of Hangzhou

Recruiting

Safety and Efficacy of PDT vs RFA vs PDT+RFA for the Treatment of Extrahepatic Cholangiocarcinoma

Bile Duct Cancer | Extrahepatic Cholangiocarcinoma

China
CHU de Reims

Completed

Pancreatico-biliary Tumor Mutation Profiling in Bile Samples (ONCOBIL)

Cholangiocarcinoma, Cancer of the Head of the Pancreas

France
National Cancer Institute (NCI)

Active, not recruiting

Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer

Recurrent Gallbladder Carcinoma | Metastatic Gallbladder Carcinoma | Stage IV Gallbladder Cancer AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IV Distal Bile Duct Cancer AJCC v8 | Metastatic Intrahepatic Cholangiocarcinoma | Recurrent Intrahepatic Cholangiocarcinoma | Metastatic... and other conditions

United States
Pfizer
Merck KGaA, Darmstadt, Germany; Ono Pharmaceutical Co. Ltd; Pierre Fabre Medicament

Completed

Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With a Safety Lead-in of Encorafenib + Binimetinib + Cetuximab in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer (BEACON CRC)

BRAF V600E-mutant Metastatic Colorectal Cancer

United States, Spain, Korea, Republic of, United Kingdom, Australia, Czechia, Taiwan, Belgium, France, Hungary, Canada, Japan, Russian Federation, Netherlands, Israel, Germany, Turkey, Austria, Brazil, Poland, Italy, Argentina, Chile, Denmar... and more
Oncolytics Biotech
Montefiore Medical Center

Completed

Study of REOLYSIN® in Combination With FOLFIRI and Bevacizumab in FOLFIRI Naive Patients With KRAS Mutant Metastatic Colorectal Cancer

KRAS Mutant Metastatic Colorectal Cancer

United States
Memorial Sloan Kettering Cancer Center
AstraZeneca; Genentech, Inc.

Completed

Osimertinib and Bevacizumab as Treatment for EGFR-mutant Lung Cancers

Non-small Cell Lung Cancer | EGFR-mutant Lung Cancers

United States
Methodist Health System

Enrolling by invitation

Treat Primary and Metastatic Liver Tumors

Metastatic Cancer | Intrahepatic Cholangiocarcinoma | Liver Tumor | Metastatic Liver Cancer

United States
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Colorectal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bile Duct Neoplasms | Metastatic Colorectal Cancer (Mcrc) | Intrahepatic Cholangiocarcinoma (Icc) | Intrahepatic Bile Duct Cancer

United States
Oslo University Hospital

Recruiting

Liver Transplantation for Non-resectable Perihilar Cholangiocarcinoma (TESLA II)

Bile Duct Cancer | Klatskin Tumor | Perihilar Cholangiocarcinoma

Norway
Shanghai Cancer Hospital, China

Unknown

Efficacy and Safety of Platinum-based Chemotherapy + Bevacizumab + Durvalumab, and Salvage SBRT for IV Non-Small Cell Lung Cancer Patients With EGFR Mutations After Failure of First Line Osimertinib: A Multicenter, Prospective, Phase II Clinical Study

Lung Cancer Stage IV，EGFR-mutant，TKI，PD-L1，SBRT

China
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

Treatment With Azacitidine of Recurrent Gliomas With IDH1/2 Mutation (AGIR)

Recurrent IDH1/2 Mutated Glioma

France
Soon Chun Hyang University

Completed

Single Versus Multiple Deployment of Metallic Stents for Inoperable Malignant Hilar Biliary Obstruction

Klatskin Tumor

Korea, Republic of
University of Zurich

Completed

Adjuvant Cisplatin Plus Gemcitabine in Operable Cholangiocellular Carcinoma.

Cholangiocellular Carcinoma

Switzerland
University of Utah

Terminated

Liver Transplantation for Cholangiocarcinoma

Cancer | Cholangiocarcinoma | Liver

United States
University of Athens

Completed

Cytological Evaluation of Biliary Epithelium After Endoscopic Sphincterotomy

Cholangiocarcinoma | Endoscopic Sphincterotomy

Greece
Mercy Research

Completed

Stereotactic Body Radiotherapy for Liver Tumors

Hepatocellular Carcinoma | Intrahepatic Cholangiocarcinoma | Liver Metastases

United States
Shanghai Jiao Tong University School of Medicine
RenJi Hospital; Huashan Hospital; Ruijin Hospital; Eastern Hepatobiliary Surgery...

Unknown

Chemothetapy FORFIRINOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

Gallbladder Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct

China
Shanghai Jiao Tong University School of Medicine
RenJi Hospital; Huashan Hospital; Ruijin Hospital; Eastern Hepatobiliary Surgery... and other collaborators

Unknown

Molecularly Target Therapy With GEMOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

Gallbladder Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct

China
Poitiers University Hospital
Sport & Collection 2019

Withdrawn

Pilot Study on the Evaluation of Irreversible Electroporation Technique in Infiltrating Perihilar Cholangiocarcinoma (HOPE)

Cholangiocarcinoma | Interventional Imaging
Abramson Cancer Center of the University of Pennsylvania

Completed

Study of Gemcitabine, Irinotecan and Panitumumab in Patients With Advanced and Metastatic Biliary Tract Adenocarcinoma

Cholangiocarcinoma | Biliary Cancer

United States
Chinese University of Hong Kong

Completed

Treatment for Bile Duct Cancer in the Liver

Cholangio Carcinoma

Hong Kong
Jordan Kharofa

Withdrawn

Neoadjuvant Therapy in Biliary Adenocarcinoma

Cholangiocarcinoma | Biliary Cancer

United States
Fondazione del Piemonte per l'Oncologia

Unknown

Biliary Cancer in Italy: a Study on Cholangiocarcinoma cAUSEs and Risk Factors

Cholangiocarcinoma

Italy
University of Zurich

Completed

Downsizing of Unresectable Cholangiocarcinoma by Combined Intravenous and Intra-arterial Chemotherapy

Cholangiocellular Carcinoma

Switzerland
Jonsson Comprehensive Cancer Center

Not yet recruiting

Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent and/or Progressive Diffuse Hemispheric Glioma, H3 G34-mutant

Diffuse Hemispheric Glioma, H3 G34-Mutant

United States
UNC Lineberger Comprehensive Cancer Center
GlaxoSmithKline

Completed

LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations

Unresectable Melanoma | Stage IV Melanoma | Stage III Melanoma | BRAF Mutant Melanoma

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
VU University of Amsterdam

Recruiting

EUS-guided Choledochoduodenostomy for Primary Drainage of Malignant Distal Biliary Obstruction (SCORPION-II-p)

Pancreas Neoplasm | Distal Cholangiocarcinoma | Biliary Obstruction

Netherlands
Shanghai Jiao Tong University School of Medicine
RenJi Hospital; Huashan Hospital; Ruijin Hospital; Eastern Hepatobiliary Surgery... and other collaborators

Unknown

Molecularly Target Therapy With FORFIRINOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

Gallbladder Cancer | Cholangiocarcinoma of the Extrahepatic Bile Duct

China
Marina N Sharifi
Novartis; University of Wisconsin, Madison

Recruiting

Alpelisib (BYL719) in Combination With Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast Cancer

Hormone Receptor Positive Breast Carcinoma | HER2-negative Breast Cancer | PIK3CA Mutant Metastatic Breast Cancer

United States
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Not yet recruiting

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen (CHONQUER)

Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
Arog Pharmaceuticals, Inc.

Completed

Study of Crenolanib for the Treatment of Patients With Advanced GIST With the D842-related Mutations and Deletions in the PDGFRA Gene

D842-related Mutant GIST

United States
Zhejiang Cancer Hospital

Recruiting

Prospective Observational Study to Predict the Response of Biliary Tract Tumors to Immunotherapy

Cholangiocarcinoma | Biliary Tract Tumor

China
TransThera Sciences (Nanjing), Inc.

Available

Rollover Study to Provide Continued Access to TT-00420 (Tinengotinib) for Subjects With Advanced Solid Tumors

Advanced Solid Tumors | Cholangiocarcinoma

United States
Johns Hopkins University

Recruiting

Percutaneous Cholangiopancreatoscopy Registry

Cholelithiasis | Choledocholithiasis | Biliary Stricture | Cholangiocarcinoma, Intrahepatic | Biliary Stones

United States
University Hospital Erlangen

Completed

Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study (ESCULAP)

Liver Diseases | Liver Cirrhosis | Liver Neoplasms | Hepatocellular Carcinoma | Liver Cancer | Cholangiocarcinoma, Intrahepatic

Germany
Weill Medical College of Cornell University

Terminated

RFA RCT for Pancreatic or Bile Duct Cancer (RFARCT)

Cholangiocarcinoma Non-resectable | Unresectable Pancreatic Cancer

United States
Washington University School of Medicine

Completed

A Feasibility Phase II Study in the Treatment of Resected Cholangiocarcinoma, Gallbladder, Pancreatic and Ampullary Cancers

Pancreatic Cancer | Gallbladder Cancer | Ampullary Cancer | Cholangiocarcinoma Cancer

United States
University Health Network, Toronto
AbbVie; Celgene

Terminated

Study of Enasidenib and Venetoclax in IDH2-Mutated Blood Cancers

Acute Myeloid Leukemia | Relapsed Cancer | Refractory Cancer | IDH2 Gene Mutation

Canada
Clinical Hospital Colentina
Catholic University, Italy

Completed

EUS Evaluation of CBD Diameter in Malignant Obstructive Jaundice (ECCO)

Pancreatic Cancer | Jaundice, Obstructive | Cholangiocarcinoma of the Extrahepatic Bile Duct | Ampulla of Vater Cancer

Romania
National Cancer Institute (NCI)

Active, not recruiting

A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer

Combined Hepatocellular Carcinoma and Cholangiocarcinoma | Stage III Liver Cancer | Stage IV Liver Cancer

United States

Clinical Trials on IDH1-mutant Cholangiocarcinoma

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