Clinical Trials on Immune Checkpoint Inhibitors in Australia

Total 2408 results

Flinders University
Flinders Medical Centre; Lyell McEwin Hospital

Recruiting

Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors (MIICI)

Myocardial Injury | Myocarditis | Cardiotoxicity | Immune Checkpoint Inhibitors

Australia
MacroGenics

Recruiting

A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer Recurrent | Immunotherapy | Androgen-Independent Prostatic Cancer | Androgen-Resistant Prostatic Cancer | Hormone Refractory Prostatic Cancer | Immune Checkpoint Inhibitor | Androgen-Independent Prostatic Neoplasms | Androgen-Insensitive Prostatic Cance | Inhibitory Checkpoint Molecule

United States, Spain, France, Belgium, United Kingdom, Poland, Georgia, Bulgaria, Puerto Rico, Australia
Medical University of Graz

Completed

Probiotic Modulation of Intestinal Microbiota in Long-term Intake of Proton Pump Inhibitors

Patients on Long-term Proton Pump Inhibitor Therapy

Austria
ModernaTX, Inc.
AstraZeneca

Active, not recruiting

Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies

Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or Lymphoma | Dose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma

United States, Israel, Australia
Novo Nordisk A/S

Active, not recruiting

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors (explorer8)

Haemophilia A Without Inhibitors | Haemophilia B Without Inhibitors

Spain, United States, Korea, Republic of, United Kingdom, Australia, Lithuania, France, Turkey, India, Estonia, Russian Federation, Ukraine, Mexico, Japan, South Africa, Serbia, Canada, Croatia, Algeria, Bosnia and Herzegovina, ... and more
Novo Nordisk A/S

Active, not recruiting

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors (explorer7)

Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Spain, Korea, Republic of, India, Australia, United Kingdom, Russian Federation, Poland, Ukraine, Thailand, Mexico, United States, Turkey, Japan, South Africa, Serbia, France, Croatia, Denmark, Algeria, Bulgaria, Malaysia, Portugal, Slovaki... and more
CSL Behring

Completed

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Emphysema | Alpha 1-proteinase Inhibitor Deficiency

Australia, Canada, Czech Republic, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden
Pharvaris Netherlands B.V.

Active, not recruiting

Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II (HAE CHAPTER-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Poland, Germany, Austria, Bulgaria, Canada, Ireland, Italy, United Kingdom
German Breast Group
Pfizer; AGO Study Group; Breast International Group; NSABP Foundation Inc

Completed

A Study of Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery (PENELOPE-B)

Breast Cancer | Hormonreceptor Positive | Her2-normal | Postneoadjuvant Treatment With CDK 4/6 Inhibitor | CPS-EG Score

United States, Australia, Austria, Canada, France, Germany, Ireland, Japan, Korea, Republic of, Spain, United Kingdom
CSL Limited

Completed

Ig NextGen 10% in Idiopathic Thrombocytopenic Purpura (ITP) Patients

Idiopathic Thrombocytopenic Purpura (ITP)

Australia
CSL Limited

Completed

Ig NextGen 10% in Patients With Primary Immune Deficiency (PID)

Primary Immune Deficiency (PID)

Australia
Novo Nordisk A/S

Completed

A Study Following People With Haemophilia A and B, With or Without Inhibitors, When on Usual Treatment (Explorer™6) (explorer™6)

Haemophilia A With Inhibitors | Haemophilia B With Inhibitors | Haemophilia A | Haemophilia B

France, United States, India, Mexico, United Kingdom, Netherlands, Sweden, Korea, Republic of, Spain, Switzerland, Serbia, Turkey, Bulgaria, Italy, Japan, Poland, South Africa, Croatia, Algeria, Australia, Bosnia and Herzegovina, ... and more
Bayside Health

Completed

Efficacy Study of Outpatient Therapy for Lymphoma

Non-Hodgkin's Lymphoma | Hodgkin's Disease

Australia
Vyne Therapeutics Inc.

Completed

Safety, Pharmacokinetics and Efficacy of FMX114 Versus Vehicle in Adults With Atopic Dermatitis

Atopic Dermatitis

United States, Australia
SinoMab BioScience Ltd

Unknown

A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Health Subject

Autoimmune Diseases

Australia
University Hospital Inselspital, Berne
European Cardiovascular Research Center

Completed

GLOBAL LEADERS Adjudication Sub-Study (GLASSY)

Coronary Artery Disease | Platelet-aggregation Inhibitors

Bulgaria, Switzerland, Austria, Belgium, Germany, Italy, Netherlands, Poland, United Kingdom
Sinocelltech Ltd.

Not yet recruiting

Evaluate the Safety and Tolerability of SCT650C in Healthy Volunteers

Autoimmune Disease

Australia
Kirby Institute
Bristol-Myers Squibb; GlaxoSmithKline; Merck Sharp & Dohme LLC; Roche Pharma AG; Boehringer... and other collaborators

Completed

Can Resistance Enhance Selection of Treatment? (CREST)

HIV Infection

Australia
Merck KGaA, Darmstadt, Germany
Merck Serono Australia Pty Ltd

Completed

Post Marketing Surveillance Study to Evaluate the Tolerability of Rebif® New Formulation in Patients With Relapsing Multiple Sclerosis in an Australian Clinical Setting. (ReNew)

Multiple Sclerosis

Australia
KoBioLabs
Novotech (Australia) Pty Limited

Completed

Study of Multiple Ascending Dose of KBL693 in Healthy Participants

Moderate to Severe Asthma

Australia
Incannex Healthcare Ltd

Recruiting

Safety and Effect on Pain and Function According to RAPID-3 of IHL-675A in Patients With Rheumatoid Arthritis (CHAPPII)

Rheumatoid Arthritis

Australia
Novo Nordisk A/S

Completed

Observational Registry of NovoSeven® Used as On-demand Treatment of Bleeds in Patients With Haemophilia A and B With Inhibitors (ONE)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Saudi Arabia, Algeria, Turkey, Germany, Poland, Netherlands, Italy, Belgium, South Africa, United Kingdom, Sweden, Austria, Portugal, France, Czech Republic, Venezuela
Kirby Institute
Government of Western Australia, Department of Health; Western Australia AIDS...

Completed

Western Australian Pre-exposure Prophylaxis for HIV Implementation Trial (PrEPIT-WA)

HIV Prevention

Australia
Shanghai Medinno Pharmaceutical Technology Co.,...

Recruiting

A Study of MDI-1228_mesylate Ophthalmic Solution in Healthy Adults

Allergic Conjunctivitis

Australia
Trans Tasman Radiation Oncology Group
Australasian Leukaemia and Lymphoma Group

Completed

Idarubicin Based Combined Modality Therapy in Primary CNS Lymphoma

Primary Central Nervous System Lymphoma

Australia, New Zealand
Connect Biopharma Australia Pty Ltd

Completed

A Study to Investigate the Effects of CBP-307 on the Heart Rate-corrected QT Interval (QTc) in Healthy Subjects

Autoimmune Diseases

Australia, United States
CSL Limited

Completed

Subcutaneous Ig NextGen 16% in PID Patients

Primary Immunodeficiency (PID)

Australia, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Molecular Genetic Lesions and Clinical Outcomes in Children With Acute Lymphoblastic Leukemia

Leukemia

Australia
De Motu Cordis
Novotech (Australia) Pty Limited

Not yet recruiting

Study of Inhaled DMC-IH1 and Intramuscular (EpiPen®) Epinephrine in Healthy Male and Female Participants.

Anaphylactic Reaction

Australia
Central Adelaide Local Health Network Incorporated
Vaxine Pty Ltd

Unknown

Study of Sting Challenge and Serological Responses to Jack Jumper Venom Immunotherapy With Inulin as Adjuvant (Jumpvax) (Jumpvax)

Immunotherapy | Ant Sting

Australia
R.P.Herrmann
Royal Perth Hospital

Unknown

Mesenchymal Stromal Cells for Acute Graft Versus Host Disease

Acute GVH Disease

Australia
Protalex, Inc.

Terminated

Phase I Safety and Tolerability Study of Staphylococcal Protein A in Adult Patients With Chronic ITP

Idiopathic Thrombocytopenic Purpura (ITP)

Australia, New Zealand
Innocare Pharma Australia Pty Ltd

Completed

A Phase I Study of ICP-022 in Healthy Subjects

Rheumatoid Arthritis | Systemic Lupus Erythematosus

Australia
Eli Lilly and Company

Active, not recruiting

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer) (CYCLONE 3)

Urogenital Neoplasms | Prostatic Neoplasms | Neoplasm Metastasis | Enzyme Inhibitors | Antineoplastic Agents | Hormones | Physiological Effects of Drugs | Antineoplastic Agents, Hormonal | Androgens | Hormones, Hormone Substitutes, and Hormone Antagonists | Abiraterone Acetate | Steroid Synthesis Inhibitors | Cytochrome... and other conditions

China, Canada, France, United States, Australia, Czechia, Hungary, Spain, Germany, Japan, Taiwan, Netherlands, Mexico, Belgium, Korea, Republic of, Turkey, Argentina, Romania, United Kingdom, Italy, Israel, Brazil, Poland, Greece
Bayside Health
Monash University; Austin Health; Rockefeller University; The Peter Doherty Institute... and other collaborators

Completed

Imaging the HIV Reservoir

HIV

Australia
Suzhou Connect Biopharmaceuticals, Ltd.
Tigermed Consulting Co., Ltd; Nucleus Network Ltd

Completed

Phase 1 Study Accessing the Safety and Tolerability of CBP-307

Autoimmune Diseases

Australia
Solarea Bio, Inc

Recruiting

SBD121, a Synbiotic Medical Food for RA Management

Rheumatoid Arthritis

Australia, New Zealand
Murdoch Childrens Research Institute

Recruiting

Analysing HIgh Dose Probiotic Peanut Oral Immunotherapy (PPOIT) and High Dose Peanut Oral Immunotherapy (OIT) Versus LOw Dose Peanut OIT for Peanut Allergy (HILO)

Peanut Allergy

Australia
Pipeline Therapeutics, Inc.

Completed

Phase I Study Evaluating Safety and Tolerability of Escalating Single and Multiple Doses of of PIPE-307 and Food Effect in Healthy Volunteers

Multiple Sclerosis

Australia
Novo Nordisk A/S

Completed

A Trial Evaluating the Efficacy and Safety of Prophylactic Administration of Concizumab in Haemophilia A and B Patients With Inhibitors (explorer™4)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

United States, Austria, Spain, Japan, Croatia, Italy, United Kingdom, Israel, Sweden, Ukraine, Malaysia, Greece, Denmark, Canada
Tunitas Therapeutics, Inc.
Tunitas Therapeutics Australia Pty Ltd

Terminated

Escalating Single Dose Study of Epsi- Gam in Healthy Normal Subjects

Allergy and Immunology

Australia
Janssen-Cilag Pty Ltd

Completed

An Efficacy and Safety Study of Autologous Cluster of Differentiation 34 (CD34+) Hematopoietic Progenitor Cells Transduced With Placebo or an Anti- Human Immunodeficiency Virus Type 1 (HIV-1) Ribozyme (OZ1) in Participants With HIV-1 Infection

HIV-1

Australia
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN); Tunitas Therapeutics, Inc.

Terminated

Safety Evaluation of an Experimental Treatment, Intradermal Human Fcγ1-Fel d1 Fusion Protein (GFD), for Cat Allergy

Cat Allergy

Australia
Athos Therapeutics Inc
Syneos Health; Athos Therapeutics Australia Pty Ltd

Completed

Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ATH-063 in Healthy Subjects

Autoimmune Diseases | Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis

Australia
Pfenex, Inc

Completed

Comparison Study of PF530 and Betaferon in Healthy Subjects

Multiple Sclerosis

Australia
Syneos Health
AprilBio Co., Ltd.

Completed

Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of APB-R3

Still's Disease, Adult-Onset

Australia
University of Adelaide
Australasian Hyperbaric & Diving Medicine Research Trust

Completed

Does Hyperbaric Oxygen Therapy Lead to a Sustained Increase in Insulin Sensitivity? (HOTAIR3)

Overweight and Obesity | Insulin Sensitivity

Australia
University of Melbourne
The Alfred; ViiV Healthcare

Completed

Dolutegravir Impact on Residual Replication (DIORR)

HIV

Australia
The University of Queensland
University of Adelaide

Not yet recruiting

REmission in Membranous Nephropathy International Trial (REMIT) (REMIT)

Primary Membranous Nephropathy

Australia
Novartis Pharmaceuticals

Completed

Efficacy and Safety Study of QAW039 in the Treatment of Patients With Moderate to Severe Atopic Dermatitis.

Atopic Dermatitis

South Africa, Belgium, Germany, Australia, Netherlands, Bulgaria, Austria, Romania

Clinical Trials on Immune Checkpoint Inhibitors in Australia

Sponsors and Collaborators

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CROs in United Kingdom

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