Clinical Trials on Immune Checkpoints Inhibitors in United Kingdom

Total 24561 results

St Stephens Aids Trust

Completed

Abacavir Pharmacokinetic Study in the Absence/Presence of Darunavir/Ritonavir or Raltegravir in HIV-infected Subjects

HIV

United Kingdom
University of Reading
Danisco

Completed

The Effect of a Prebiotic, Probiotic and Synbiotic on the Gut Microbiota and Immune Response of Older Volunteers (GOS)

Gut Microbiota | Immune Function

United Kingdom
Novo Nordisk A/S

Completed

Observational Patient Diary Study of Treatment Doses for Patients With Haemophilia With Inhibitors to Factors VIII and IX (DOSE)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

United States
Ratiopharm GmbH

Completed

Multiple Dose BE Study With Nevirapine 400mg PR Tablets

HIV-1

United Kingdom
German Breast Group
Pfizer; AGO Study Group; Breast International Group; NSABP Foundation Inc

Completed

A Study of Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery (PENELOPE-B)

Breast Cancer | Hormonreceptor Positive | Her2-normal | Postneoadjuvant Treatment With CDK 4/6 Inhibitor | CPS-EG Score

United States, Australia, Austria, Canada, France, Germany, Ireland, Japan, Korea, Republic of, Spain, United Kingdom
University of Edinburgh
Allergy UK

Completed

Allergy UK Research and Development Nurse Project (ALLUKN)

Allergy

United Kingdom
University of Nottingham

Completed

Test@Work Study: Evaluation of Attitudes and Uptake Within Employee Health Checks in the Construction Industry (Test@Work)

HIV

United Kingdom
GlaxoSmithKline
Quotient Clinical

Completed

A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses

Autoimmune Diseases

United Kingdom
GlaxoSmithKline
Quotient Sciences

Completed

A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772

Autoimmune Diseases

United Kingdom
St Stephens Aids Trust
ViiV Healthcare

Completed

The Pharmacokinetics of Dolutegravir, Darunavir/Cobocistat When Co-administered in Healthy Volunteers (SSAT073)

HIV

United Kingdom
St Stephens Aids Trust
Bristol-Myers Squibb

Terminated

Pharmacokinetic Effect of Evotaz/Microgynon Co-administration

HIV

United Kingdom
GlaxoSmithKline

Completed

A Single and Repeat Dose PK/PD Study to Characterise Biomarker Response in Healthy Subjects Treated With Azithromycin

Autoimmune Diseases

United Kingdom
St Stephens Aids Trust
Merck Sharp & Dohme LLC

Completed

Renal Integrase Study

HIV

United Kingdom
St Stephens Aids Trust

Completed

A Study to Assess Cerebrospinal Fluid INflammatory Markers After Addition of Maraviroc to MONotherapy Darunavir/Ritonavir - The CINAMMON Study (CINAMMON)

HIV

United Kingdom
Helen Reynolds

Completed

The Effect of Antacids and Multivitamins on Raltegravir

HIV

United Kingdom
PX'Therapeutics
European Commission

Completed

Safety & Immunogenicity of Immunisations With EN41-UGR7C HIV Vaccine

- HIV

United Kingdom
St Stephens Aids Trust

Completed

Pilot Study Switching Individuals Receiving EFV With Continuing Central Nervous System Toxicity to TMC125

HIV

United Kingdom
Pierre Fabre Dermo Cosmetique

Unknown

Oral and Dental Tolerance and Efficacy on Dentinal Hypersensitivity of a Dental Gel, on Adults

Dentinal Hypersensitivity

United Kingdom
University of Arizona

Completed

Evaluation of Blood/Imaging Based Biomarkers, Aromatase Inhibitor Induced Musculoskeletal Syndrome

Breast Cancer | Aromatase Inhibitor Induced Musculoskeletal Syndrome (AIMSS)

United States
Imperial College London

Completed

Pharmacokinetics of Intramuscular Adrenaline in Food--Allergic Teenagers (PIMAT)

Anaphylaxis

United Kingdom
Novo Nordisk A/S

Completed

Efficacy and Safety of NNC 0078-0000-0007 in Patients With Congenital Haemophilia and Inhibitors (adept™2)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Taiwan, United Kingdom, Thailand, Serbia, Croatia, Italy, Poland, Romania, Hungary, Malaysia, United States, Austria, Brazil, Greece, Japan, Puerto Rico, Russian Federation, South Africa, Turkey
St Stephens Aids Trust

Completed

Men Who Have Sex With Men (MSM) Neurocog 1&2 Study (MSM Neurocog)

HIV Related Neurocognitive Impairment

United Kingdom
St Stephens Aids Trust

Completed

A Two Way Cross Over Pharmacokinetic Interaction Study Between Raltegravir and Amlodipine in Healthy Volunteers

HIV

United Kingdom
University Hospital Southampton NHS Foundation...
Royal Marsden NHS Foundation Trust; University College London Hospitals; Cambridge... and other collaborators

Unknown

Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults. (ImmunoCOVID)

COVID | Infection | Immune Deficiency | Immune Suppression | Children, Adult

United Kingdom
St Stephens Aids Trust
Gilead Sciences

Completed

SSAT058: Atripla to Eviplera Switch in Patients Without Central Nervous System Symptoms

HIV

United Kingdom
Artax Biopharma Inc
Simbec-Orion Group

Completed

A Study of the Safety, Tolerability, Pharmacokinetics and Food Effect After Single and Multiple Ascending Oral Doses

Autoimmune Diseases

United Kingdom
Imperial College London
European Commission

Completed

The Safety and Immunogenicity of the DNA-GTU Vaccine Administered to HIV-infected Patients on ART vs Placebo (CUTHIVTHER001)

HIV

United Kingdom
Imperial College London
CUT'HIVAC Cutaneous HIV Vaccination

Unknown

Immunogenicity of Three HIV GTU® MultiHIV DNA Immunisations Administered Via Intramuscular, Intradermal and Transcutaneous Routes (CUT*HIVAC001)

HIV

United Kingdom
Unilever SEAC

Completed

Study to Evaluate the Potential of Air Structuring Protein to Elicit Allergic Reactions in Mold Sensitized People

Allergy to Mold

United Kingdom
Ono Pharmaceutical Co. Ltd

Completed

A Study to Investigate the Effect of ONO-8539 on Acid-Induced Oesophageal Hypersensitivity in Healthy Volunteers

Acid Reflux

United Kingdom
Barts & The London NHS Trust
University College, London

Not yet recruiting

Immune Responsiveness and Outcome After Aortic Valve Surgery (Measure) (Measure)

Aortic Valve Disease | Surgery--Complications | Immune System Disorder

United Kingdom
King's College London

Recruiting

Snack Foods and Their Impact on the Immune Response Following Influenza Vaccination (NutrImmune)

Immune Response

United Kingdom
York Teaching Hospitals NHS Foundation Trust
University of York; York St John University

Recruiting

CytoHealth - A Study of the Inflammatory Response to Exercise (CytoHealth)

Inflammatory Response | Immune System

United Kingdom
PX'Therapeutics
European Commission

Completed

EuroNeut41: Safety & Immunogenicity of Immunisations With HIV Vaccine

HIV

United Kingdom
Maruho Europe Limited

Completed

Drug-Drug Interaction Study: ASP2151 and Ritonavir

Healthy

United Kingdom
GlaxoSmithKline

Completed

A Single Dose Study to Assess the Regional Absorption and Bioavailability of 100mg GSK2190915A

Asthma

United Kingdom
Research in Real-Life Ltd
Napp Pharmaceuticals Limited

Completed

A Guideline Approach to Therapy Step-down Utilising Flutiform Change and Step-down

Asthma

United Kingdom
Mundipharma Research Limited

Completed

A Pharmacokinetic/Pharmacodynamic Inhaler Comparison Study in Healthy Volunteers

Asthma

United Kingdom
James Tysome
University of Cambridge

Recruiting

The Accuracy of Sonotubometry to Assess the Eustachian Tube

Eustachian Tube Dysfunction

United Kingdom
University of Nottingham
Pfizer

Recruiting

Checkpoint Inhibitor-induced Liver Injury (ChILI)

Immune-Mediated Hepatitis

United Kingdom
University of Leicester
Oxford University Hospitals NHS Trust; Medicines Evaluation Unit Ltd; AnaptysBio...

Completed

Analysis of Peripheral Blood ILC2s and Th2 Cells in Response to ANB020

Asthma

United Kingdom
GlaxoSmithKline

Completed

A Study to Assess the Systemic Exposure of FLIXOTIDE™ (Fluticasone Propionate) and SERETIDE™ (Fluticasone Propionate and Salmeterol) Given With VENTOLIN™ Mini-Spacer Compared to the Aerochamber Plus Spacer

Asthma

United Kingdom
St. Francis Hospital, New York

Unknown

Plavix, Prasugrel and Drug Eluting Stents Pilot Trial (PPD)

Coronary Artery Disease | Platelet Aggregation Inhibitors | PCI- Percutaneous Coronary Intervention

United States
University of Aberdeen

Unknown

Bakery Products for Non-Coeliac Gluten Sensitive Consumers

Non Coeliac Gluten Sensitivity

United Kingdom
Bristol-Myers Squibb

Completed

Dose Finding Confirmation of Atazanavir With Ritonavir and Efavirenz (ATV/RTV + EFV) in Healthy Subjects

HIV Infections | Protease Inhibitor

United States
Bristol-Myers Squibb

Completed

Atazanavir Twice Daily

HIV Infections | Protease Inhibitor

United States
Imperial College London
National Institute for Health Research, United Kingdom

Completed

Intranasal Diagnostics in Food Allergy: a Feasibility Study (INDY)

Food Allergy

United Kingdom
University of Reading
Danisco

Completed

A Study of a Prebiotic, a Probiotic and a Synbiotic Upon the Gut Microbiota and Immune Response of Healthy Volunteers (XOS)

Gut Microbiota | Immune Function | Bowel Function | Plasma Lipids

United Kingdom
University of Cambridge
University of Oxford; Stanley Medical Research Institute; McPin Foundation

Completed

Study of Immunotherapy in Autoantibody Positive Psychosis (SINAPPS-1)

Schizophrenia | Psychosis | Auto Immune Disorders

United Kingdom
University of Maryland, Baltimore
National Heart, Lung, and Blood Institute (NHLBI); National Institute of General...

Completed

Determining Genetic Role in Treatment Response to Anti-Platelet Interventions (The PAPI Study)

Coronary Heart Disease | Platelet Aggregation Inhibitors

United States

Clinical Trials on Immune Checkpoints Inhibitors in United Kingdom

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