Clinical Trials on Immune System Diseases in South Africa

Total 18787 results

New York State Psychiatric Institute
Brown University; Medical Research Council, South Africa

Active, not recruiting

A Gender-Enhanced Pre-Exposure Prophylaxis (PrEP) Information-Motivational Workshop for Young South African Women (Masibambane)

HIV Infections

South Africa
Massachusetts General Hospital
Harvard Medical School (HMS and HSDM); National Institute of Allergy and Infectious... and other collaborators

Completed

Population Effectiveness of Dolutegravir Implementation in Sub-Saharan Africa (DISCO)

HIV-1-infection

Uganda, South Africa
RTI International
University of Cape Town

Completed

Treating South African Pregnant Women for Methamphetamine

HIV | Drug Addiction

South Africa
University of KwaZulu
Bristol-Myers Squibb

Completed

Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women

Puerperal Sepsis

South Africa
Minervax ApS
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Study of a Group B Streptococcus Vaccine in Pregnant Women Living With HIV and in Pregnant Women Who do Not Have HIV

Group B Streptococcal Infection

South Africa, Uganda
Columbia University
Centre for the AIDS Programme of Research in South Africa

Not yet recruiting

An Adaptive Randomized Controlled Trial (ADAP-TIV)

HIV Infections | Multi Drug Resistant Tuberculosis

South Africa
Aeras
University of Oxford; European and Developing Countries Clinical Trials Partnership...

Completed

Efficacy Against TB Disease, Safety, and Immunogenicity of MVA85A/AERAS-485 in HIV-Infected Adults (C-030-485)

HIV Infections | Tuberculosis

South Africa, Senegal
CIPRA SA
National Institute of Allergy and Infectious Diseases (NIAID); Comprehensive...

Completed

Characteristics and Prevalence of Tuberculosis and HIV in Masiphumelele Township, Cape Town, South Africa

HIV Infections | Tuberculosis

South Africa
French National Agency for Research on AIDS and...

Completed

Evaluation of the Extension at Community Level of Safe Male Circumcision (ANRS 12126 ORANGE FARM 2) (ORANGE FARM 2)

HIV Infections

South Africa
Wellcome Trust Liverpool Glasgow Centre for Global...
Professor David Lalloo; Professor Hamish Simpson; Professor William J Harrison; Professor Sithombo Maqungo

Unknown

HIV in Orthopaedic Skeletal Trauma Study (HOST)

Fracture Healing in HIV-positive Patients

South Africa
Centre for the AIDS Programme of Research in South...
Doris Duke Charitable Foundation

Completed

An Enhanced Adherence Support Programme for Highly Active Antiretroviral Therapy (HAART) (eASP)

HIV Infections

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Strategies for Delivering Anti-HIV Therapy in South Africa

HIV Infections

South Africa
Duke University
The Emmes Company, LLC

Recruiting

Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana (BMS02)

HIV Infections | Lactating Women on Select DOI | Breastmilk Fed Infants of Mothers on Select DOI

South Africa
University of Cape Town

Recruiting

Testing New Strategies for Patients Hospitalised With HIV-associated Disseminated Tuberculosis (NEW-STRAT TB)

HIV | Disseminated Tuberculosis

South Africa
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Obesogenic Origins of Maternal and Child Metabolic Health Involving Dolutegravir (ORCHID)

Obesity | HIV | Maternal Obesity During Childbirth | Maternal Obesity Complicating Pregnancy | Obesity, Infant

South Africa
Massachusetts General Hospital
Bill and Melinda Gates Foundation; Mbarara University of Science and Technology and other collaborators

Completed

Examining HIV Treatment Adherence During Early Disease (META)

HIV | Medication Adherence

South Africa, Uganda
IDRI
Wellcome Trust; South African Tuberculosis Vaccine Initiative

Completed

Phase 2a ID93 + GLA-SE Vaccine Trial in TB Patients After Treatment Completion

Pulmonary Tuberculosis

South Africa
French National Agency for Research on AIDS and...

Terminated

Effect of Male Circumcision on HIV Incidence (ANRS 1265)

HIV Infections | Herpes Genitalis | Venereal Diseases

South Africa
University of KwaZulu
AIDS Malignancy Consortium; National Research Foundation, Singapore; AIDS Care... and other collaborators

Completed

HIV/AIDS Kaposis Sarcoma: Comparison of Response to HAART vs HAART Plus CXT (KAART)

HIV | Kaposi's Sarcoma | AIDS | Human Herpesvirus 8

South Africa
ANRS, Emerging Infectious Diseases
University of KwaZulu; Africa Centre For Health and Population Studies

Completed

Impact of Immediate Versus South African Recommendations Guided ART Initiation on HIV Incidence (TasP)

HIV Infection

South Africa
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); Makerere University and other collaborators

Completed

Cryptococcal Optimal ART Timing Trial (COAT)

HIV Infections | AIDS | Cryptococcal Meningitis

Uganda, South Africa
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC

Completed

Preparedness Study - HPV Vaccine

Sexual Transmission of Infection

United States, South Africa
Walter Sisulu University
Medical University of Graz; Nelson Mandela Academic Hospital; Umtata General...

Not yet recruiting

Cardiometabolic Health of Children Exposed to Anti-retroviral Therapy (ART) in Utero (ARTMOMSBABES)

In Utero Drug Exposure

South Africa
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Gilead Sciences and other collaborators

Completed

Uptake and Adherence to Daily Oral PrEP as a Primary Prevention Strategy for Young African Women: A Vanguard Study

HIV

South Africa, Zimbabwe
Africa Health Research Institute

Recruiting

Long-Acting HIV Pre-Exposure Prophylaxis Integrated With Sexual and Reproductive Health - cRCT (LAPIS)

HIV Infections

South Africa
Bial - Portela C S.A.

Completed

An Open-label, Multiple-dose, Single-centre Study, Investigating the Pharmacokinetics of BIA 2-093

Epilepsy

South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Acceptability, Safety, and Use of Daily Truvada Pre-Exposure Prophylaxis in Adolescents

HIV Infections

South Africa
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Point-of-care Viral Load Testing to Enable Streamlined Care and Task Shifting for Chronic HIV Care (STREAM)

Chronic HIV Infection

South Africa
University of Sussex
University of Cape Town; Africa Health Research Institute

Not yet recruiting

Optimised Electronic Patient Records to Improve Clinical Monitoring of HIV-positive Patients in Rural South Africa (MONART)

HIV Infections

South Africa
London School of Hygiene and Tropical Medicine
Department for International Development, United Kingdom; University of Witwatersrand... and other collaborators

Completed

The Intervention With Microfinance for AIDS and Gender Equity (IMAGE) Study

HIV Infections | Gender Based Violence

South Africa
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Quantiferon Gold Test for Detecting Tuberculosis (TB) Infection in HIV/AIDS Patients in South Africa

HIV | Latent Tuberculosis

South Africa
University of California, Los Angeles

Active, not recruiting

Neighborhood Alcohol & HIV Prevention in South African Townships (Philani)

Nutrition Disorders | HIV | Fetal Alcohol Syndrome

South Africa
bioLytical Laboratories

Recruiting

Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis Syphilis Ab Test at the Point- Of-Care Sites

Syphilis | Syphilis Infection

South Africa
bioLytical Laboratories

Active, not recruiting

Retrospective Study of iStatis Syphilis Ab Test (POC)

Syphilis | Syphilis Infection

South Africa
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
Centre for the AIDS Programme of Research in South...
MIET Africa; KwaZulu-Natal Department of Education; Embassy of the Kingdom of...

Completed

Reducing HIV in Adolescents (RHIVA)

HIV Infections

South Africa
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

An Exploratory Study of Potential Sources of Efficacy Dilution in the VOICE Trial (MTN-003)

HIV Prevention

Uganda, South Africa, Zimbabwe
Bayer

Completed

Dose Escalation of Different Concentrations of ZK 245186 in Atopic Dermatitis

Atopic Dermatitis

South Africa
University of Witwatersrand, South Africa
Bill and Melinda Gates Foundation

Completed

Immunogenicity and Safety of Trivalent Influenza Vaccine in Non-pregnant HIV-infected Women

Influenza | Human Immunodeficiency Virus

South Africa
Bayer

Completed

HPA Axis Study in Adults

Eczema | Atopic Dermatitis

South Africa
University of Stellenbosch
University of Pittsburgh

Unknown

TB-IRIS NSAID Cox-2 Inhibitor Prevention Trial

Tuberculosis

South Africa
RTI International
Medical Research Council, South Africa

Recruiting

Couples Health CoOp Plus (CHC+)

HIV | Substance Use | Stigma, Social

South Africa
Helen Reynolds
Desmond Tutu HIV Centre; Infectious Disease Institute, Kampala, Uganda

Active, not recruiting

Drug Interactions Between Dolutegravir and Escalating Doses of Rifampicin (DoRIS)

Tuberculosis | Hiv

Uganda, South Africa
Boehringer Ingelheim

Completed

Open Label Study of NVP+CBV Treatment in Women Who Have Received sdNVP for the pMTCT of HIV

Acquired Immunodeficiency Syndrome

South Africa
Johns Hopkins Bloomberg School of Public Health
National Institute of Mental Health (NIMH); Unity Health Toronto; TB/HIV Care

Recruiting

Project Phakama: Testing Support Strategies to Empower Young Women on PrEP in South Africa

HIV Infections | Pre-exposure Prophylaxis

South Africa
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa (RESOLVE)

HIV Infections | AIDS | Virologic Failure

South Africa, Uganda
Eastern Virginia Medical School
University of Pittsburgh; United States Agency for International Development... and other collaborators

Recruiting

Safety and PK Multi-dose Study of TAF/EVG Vaginal Insert

Safety Issues

United States, Kenya, South Africa
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

High-Dose Isoniazid Among Adult Patients With Different Genetic Variants of INH-Resistant Tuberculosis (TB)

Tuberculosis

Haiti, South Africa
University of Cape Town
London School of Hygiene and Tropical Medicine; Johns Hopkins University; Imperial... and other collaborators

Completed

Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons (HAART-IPT)

HIV Infections | Tuberculosis | Latent Tuberculosis Infection

South Africa
Elizabeth Glaser Pediatric AIDS Foundation
Harvard School of Public Health (HSPH); Centre for Infectious Disease Research... and other collaborators

Completed

Elizabeth Glaser Pediatric AIDS Foundation Maternal Events and Pregnancy Outcomes (MEP Project)A Multi-site Protocol (MEPProject)

HIV Infections | Pregnant Women | HIV Positive

South Africa, Zambia

Clinical Trials on Immune System Diseases in South Africa

Sponsors and Collaborators

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Drug Interventions

CROs by country

CROs in Zambia

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Rare Diseases

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