Clinical Trials on Immune System Diseases in United Kingdom

Total 147551 results

Mead Johnson Nutrition

Withdrawn

Evaluation of Fatty Acid Levels and Growth in Infants Fed Amino Acid Based (AA) Formulas

Cow's Milk Allergy | Intolerance to Extensively Hydrolyzed Formulas | Intolerance to Breast Milk

United Kingdom
CSL Behring

Terminated

Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous CSL730 in Healthy Adult Subjects

Immune Complex-mediated Autoimmune Diseases

United Kingdom
Kymab Limited

Completed

A Study of Subcutaneous KY1005 in Healthy Volunteers

Immune System Diseases

United Kingdom
Zealandina Agency

Completed

Mountain Food and Natural Probiotic in Nutrition

Immune Deficiency

United Kingdom
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...
Merck KGaA, Darmstadt, Germany

Completed

PK Study of Xevinapant (Debio 1143) in Healthy East Asian Participants

Healthy

United Kingdom
Galapagos NV

Completed

Drug-drug Interaction Study With GLPG3667 and Midazolam in Healthy Subjects

Healthy

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Unknown

Development of Diagnostic Pathway for Teicoplanin Allergy

Hypersensitivity

United Kingdom
GlaxoSmithKline

Completed

A Safety and Pharmacokinetic (PK) Study of GSK2982772 in Healthy Subjects

Autoimmune Diseases

United Kingdom
GlaxoSmithKline

Completed

Single Ascending Doses Study of Anti- Interleukin-7 Receptor α Monoclonal Antibody (GSK2618960) in Healthy Volunteers

Autoimmune Diseases

United Kingdom
Barts & The London NHS Trust
University College, London

Not yet recruiting

Immune Responsiveness and Outcome After Aortic Valve Surgery (Measure) (Measure)

Aortic Valve Disease | Surgery--Complications | Immune System Disorder

United Kingdom
GlaxoSmithKline
Quotient Clinical

Completed

A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses

Autoimmune Diseases

United Kingdom
GlaxoSmithKline
Quotient Sciences

Completed

A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772

Autoimmune Diseases

United Kingdom
GlaxoSmithKline

Completed

A Single and Repeat Dose PK/PD Study to Characterise Biomarker Response in Healthy Subjects Treated With Azithromycin

Autoimmune Diseases

United Kingdom
Ono Pharmaceutical Co. Ltd

Completed

A Study to Investigate the Effect of ONO-8539 on Acid-Induced Oesophageal Hypersensitivity in Healthy Volunteers

Acid Reflux

United Kingdom
University of Oxford

Completed

A Study to Assess Safety and Immunogenicity of Conserved Mosaic HIV-1 Vaccines

HIV

United Kingdom
Société des Produits Nestlé (SPN)

Terminated

Acceptability and Tolerance Study of an Amino Acid Formula With HMOs

Infant Development

United Kingdom
Imperial College London

Withdrawn

The Effect of Eating Frequency on Blood Pressure

Blood Pressure

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Completed

Penicillin Allergy De-Labelling in Elective Surgical Patients (PADLES) (PADLES)

Allergy

United Kingdom
St Stephens Aids Trust
ViiV Healthcare

Completed

SSAT064: Pharmacokinetics of Abacavir/Lamivudine/Dolutegravir in HIV Patients of 60 Years and Over

HIV

United Kingdom
St. Stephens Clinical Research

Completed

RIFT: Effect of Rifampicin on Plasma PK of FTC, TAF and Intracellular TFV-DP & FTC-TP (RIFT)

HIV

United Kingdom
St Stephens Aids Trust
Mylan Inc.

Completed

SSAT063- Pharmacokinetics of Efavirenz 400 mg Once Daily During Pregnancy in HIV-1 Infected Women

HIV

United Kingdom
St Stephens Aids Trust
University of Liverpool

Suspended

PK of Efavirenz & Lopinavir Nano-formulations in Healthy Volunteers

HIV

United Kingdom
St Stephens Aids Trust
ViiV Healthcare

Completed

SSAT061: PK of DTG and EVT/COBI in Healthy Volunteers

HIV

United Kingdom
St Stephens Aids Trust
ViiV Healthcare

Unknown

Efavirenz to Dolutegravir Switch in Patients With CNS Toxicity

HIV

United Kingdom
Imperial College London
Janssen-Cilag Ltd.

Completed

The Rilpivirine Cerebrospinal-fluid (CSF) Study

HIV

United Kingdom
St Stephens Aids Trust

Terminated

NNRTI/PI Toxicity Switch to Darunavir Study

HIV

United Kingdom
GlaxoSmithKline

Not yet recruiting

A First Time in Human Study to Evaluate the Safety and Tolerability of GSK3996401 Following Dosing With GSK4347859 in Healthy Participants

Systemic Lupus Erythematosus

United Kingdom
University College, London
University College London Hospitals

Unknown

The Role of Lipids in Immune Cell Function in SLE Patients

Lupus Erythematosus, Systemic

United Kingdom
University of Oxford

Completed

Safety and Immunogenicity of Candidate HIV Vaccines Given Sequentially

Healthy

United Kingdom
Public Health England

Withdrawn

Ethnicity Data in HIV Positive Men Who Have Sex With Men

HIV

United Kingdom
Imperial College London

Completed

The Safety, Pharmacokinetic Profile and Efficacy of Raltegravir in HIV-infected Patients at Least 60 Years of Age

HIV

United Kingdom
Imperial College London

Completed

The Maraviroc Darunavir/Ritonavir Once Daily Pharmacokinetic Study

HIV

United Kingdom
Imperial College London
Medical Research Council

Completed

Safety and Immunogenicity of HIV DNA-C CN54ENV and Recombinant HIV CN54gp140 Vaccines in Healthy Volunteers

HIV

United Kingdom
St Stephens Aids Trust

Completed

A Pilot Study to Assess the Feasibility of Switching, Individuals Receiving Atripla With Continuing Central Nervous System (CNS) Toxicity, to a Fixed Dose Combination of Tenofovir/Emtricitabine/Rilpivirine

HIV

United Kingdom
St Stephens Aids Trust

Completed

A Phase IV, Open-label Single-arm Study Investigating the Pharmacokinetics and Pharmacodynamics of the Antiretroviral Combination of Rilpivirine and Ritonavirboosted Darunavir in Therapy-naive HIV-1 Infected Patients.

HIV

United Kingdom
MRC [ycm]

Completed

Pre-exposure Option for Reducing HIV in the UK.(PROUD) (PROUD)

HIV

United Kingdom
St Stephens Aids Trust
Bristol-Myers Squibb

Completed

SSAT067 PK of Atazanavir/Cobicistat and Darunavir/Cobicistat

HIV

United Kingdom
St Stephens Aids Trust

Completed

Pharmacokinetics of Tenofovir and Tenofovir-diphosphate, Emtricitabine and Emtricitabine-triphosphate, and Rilpivirine Once Daily Over 14 Days Following Drug Intake Cessation in Healthy Volunteers

HIV

United Kingdom
Chelsea and Westminster NHS Foundation Trust
King's College Hospital NHS Trust; Public Health England; Department of Health... and other collaborators

Completed

HIV Testing in Non-traditional Settings Study (HINTS)

HIV

United Kingdom
St Stephens Aids Trust

Completed

Raltegravir and Ezetimibe PK Study

HIV

United Kingdom
St Stephens Aids Trust

Completed

Abacavir Pharmacokinetic Study in the Absence/Presence of Darunavir/Ritonavir or Raltegravir in HIV-infected Subjects

HIV

United Kingdom
Autolus Limited

Recruiting

A Study of CD19 Targeted CAR T Cell Therapy in Patients With Severe, Refractory Systemic Lupus Erythematosus (SLE) (CARLYSE)

Systemic Lupus Erythematosus

United Kingdom
UCB Biopharma S.P.R.L.
Pharmaceutical Research Associates; Richmond Pharmacology Limited; Eurofins; ACM... and other collaborators

Completed

Study to Compare Properties of Epratuzumab When Given as an Injection Under the Skin or Directly Into the Blood

Systemic Lupus Erythematosus

United Kingdom
University of Edinburgh
Allergy UK

Completed

Allergy UK Research and Development Nurse Project (ALLUKN)

Allergy

United Kingdom
University of Nottingham

Completed

Test@Work Study: Evaluation of Attitudes and Uptake Within Employee Health Checks in the Construction Industry (Test@Work)

HIV

United Kingdom
St Stephens Aids Trust
ViiV Healthcare

Completed

The Pharmacokinetics of Dolutegravir, Darunavir/Cobocistat When Co-administered in Healthy Volunteers (SSAT073)

HIV

United Kingdom
St Stephens Aids Trust
Bristol-Myers Squibb

Terminated

Pharmacokinetic Effect of Evotaz/Microgynon Co-administration

HIV

United Kingdom
St Stephens Aids Trust
Merck Sharp & Dohme LLC

Completed

Renal Integrase Study

HIV

United Kingdom
St Stephens Aids Trust

Completed

A Study to Assess Cerebrospinal Fluid INflammatory Markers After Addition of Maraviroc to MONotherapy Darunavir/Ritonavir - The CINAMMON Study (CINAMMON)

HIV

United Kingdom
Helen Reynolds

Completed

The Effect of Antacids and Multivitamins on Raltegravir

HIV

United Kingdom

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