Clinical Trials on Immune Responses

Total 54303 results

PENTA Foundation
Chiesi Farmaceutici S.p.A.

Completed

Efficacy, Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days With Clinical or Confirmed Late-onset Sepsis (NeoMero-1)

Sepsis

Italy
Emilio Bouza

Completed

Assessment of a Proposed Microbiological Alert and Its Impact on a Sepsis Campaign

Sepsis

Spain
NICHD Global Network for Women's and Children's...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Chlorhexidine Vaginal and Infant Wash in Pakistan

Sepsis | Pregnancy

Pakistan
Hopital Saint Roch

Completed

Lactate Use as Triage Tool in Sepsis : Veinous, Capillary or Arterial?

Sepsis

France
Changhai Hospital

Completed

Expression and the Clinical Significance of Neutrophil PD-L1 During Sepsis

Sepsis | Immunosuppression
Chinese PLA General Hospital

Unknown

Alpha-1-acid Glycoprotein as a Biomarker of Developmental Diagnosing and Monitoring Effectiveness in Sepsis

Sepsis | Systemic Inflammatory Response Syndrome

China
Universitätsmedizin Mannheim

Completed

Mediators of Inflammation, Prognostic Markers and Genetic Polymorphisms in Patients With Sepsis

Sepsis

Germany
Fresenius Kabi

Completed

Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis (CRYSTMAS)

Sepsis

France, Germany
Sunnybrook Health Sciences Centre
Dialysis Solutions Inc.

Completed

Cytokine Removal by CRRT in Pediatric Sepsis

Sepsis

United States
Universidad Nacional de La Plata
Clínica Bazterrica; National Agency for Scientific and Technological Promotion... and other collaborators

Completed

Saline Solution Versus Voluven®: A Controlled Study of Fluid Resuscitation in Severe Sepsis

Sepsis

Argentina
National Taiwan University Hospital

Unknown

The Biomarker and Cardiac Function in Sepsis

Sepsis

Taiwan
Eli Lilly and Company

Completed

The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death

Sepsis

Canada, Finland, Belgium, Argentina, Chile, Australia, Austria, Brazil, Czech Republic, Denmark, Egypt, France
Eli Lilly and Company

Completed

A Phase IIb Study to Determine the Efficacy and Safety of the Study Drug in Patients With Severe Sepsis

Sepsis

United States, Poland, Belgium, Netherlands, Hungary
Ain Shams University

Recruiting

CRP/Albumin Ratio as a Predictive Inflammatory Marker for Postoperative SIRS and/or Sepsis

Crp

Egypt
Children's Hospital of Philadelphia
M.D. Anderson Cancer Center; The Hospital for Sick Children; Eunice Kennedy Shriver... and other collaborators

Recruiting

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis (PRoMPT BOLUS)

Shock | Septic

United States
Brian Zuckerbraun

Completed

Effects of Metformin in a Non-Diabetic Patient Population

Inflammatory Response

United States
National Cheng-Kung University Hospital

Completed

Explore the Role of NLRP7 in the Regulation of Progestereone Induced Decidualization of Human Endometrial Stroma Cells

Inflammatory Response | Abortion, Habitual

Taiwan
Wake Forest University Health Sciences
American Heart Association

Terminated

L-Carnitine Administration in Early Sepsis

Septic Shock

United States
Duke University

Completed

The DETOURS Trial: De-escalating Empiric Treatment: Opting Out of Rx for Selected Patients With Suspected Sepsis - Opt-Out Protocol Trial

Antibiotic Stewardship

United States
Ganin Fertility Center

Unknown

Optimal Embryonic Stage for Transfer in Poor Responders

Infertility, Female | Poor Response to Ovulation Induction

Egypt
Hospital El Cruce

Unknown

Immune Profile of Patients With Sepsis (IPSEPSIS)

Sepsis, Severe
Pär Johansson

Terminated

Metabolomic Alterations in the Vascular Compartment in Patients With Sepsis (METSEP)

Endothelial Dysfunction

Denmark
Peking Union Medical College Hospital

Unknown

Multi-omics Study on Gut Microbiota in Critical Ill Patients After Cardiopulmonary Bypass (CPB-MUL-GM)

Sepsis | Cardiopulmonary Bypass

China
Hellenic Institute for the Study of Sepsis
Aristotle University Of Thessaloniki; National and Kapodistrian University...

Completed

Heparin Binding Protein in Early Sepsis Diagnosis (PROMPT)

Sepsis | Infection

Greece
B. Braun Medical Inc.

Terminated

S.A.F.E.BT System Extracorporeal Treatment With DIAPACT CRRT (SAFEbt)

Severe Sepsis

United States
Federal University of Minas Gerais
Fundação de Amparo à Pesquisa do estado de Minas Gerais

Completed

Duration of Antibiotic Therapy in Critically Ill Patients: C-reactive Protein-guided Therapy Versus Best Practice

Infection Systemic

Brazil
InflaRx GmbH

Completed

Studying Complement Inhibition in Complex Cardiac Surgery (CARDIAC)

Systemic Inflammatory Response Syndrome | C.Surgical Procedure; Cardiac

Germany
Changhai Hospital

Unknown

Expression of TIM-3 on Lymphocytes in Sepsis

Sepsis | Immunosuppression

China
Charite University, Berlin, Germany
German Federal Ministry of Education and Research; SepNet - Critical Care Trials... and other collaborators

Completed

Hydrocortisone for Prevention of Septic Shock (HYPRESS)

Severe Sepsis

Germany
InCor Heart Institute
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Effects of Exposure to Biomass-burning Air Pollution on Lung Function, Heart Rate Variability and Inflammatory Markers in Sugarcane Workers

Oxidative Stress | Heart Rate Variability | Systemic Inflammatory Response | Lung Function

Brazil
Medical University of Graz

Completed

Investigation of Correlation Between Interstitial and Arterial Blood Glucose Concentrations in Septic Patients

Severe Sepsis

Austria
University of California, Irvine

Terminated

Differences in Immunologic Response to Cryoablation Versus Radiofrequency Ablation in the Treatment of Renal Cell Carcinoma

Immune Response to 3 Approaches
University Hospital, Caen

Completed

Pediatric Intensive Care Unit and Primary Immune Deficiency (PICUPID)

Immuno-Deficiency

France
Medical University of Vienna

Completed

Cellular and Humoral Immunity in Elderly After Immunization With a Japanese Encephalitis Vaccine

Humoral and Cellular Immune Responses
University Ghent
Research Foundation Flanders

Recruiting

The Effect of Cognitive Dual-task Rehabilitation on Arthrogenic Muscle Responses After ACL Reconstruction (AMIRA)

Anterior Cruciate Ligament Reconstruction | ACL Injury | Athrogenic Muscle Responses | Arthrogenic Muscle Inhibition

Belgium
Sabine Dieperink
University of Copenhagen; University of Aarhus; Statens Serum Institut

Completed

Bloodstream Infections in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis | Staphylococcus Aureus Bacteremia
St. Antonius Hospital

Completed

Community Acquired Pneumonia: Outcome, Quality of Life and Immune Status (CAPolista)

Pneumonia | Immune Response | Streptococcus Pneumoniae

Netherlands
Centers for Disease Control and Prevention
United States Agency for International Development (USAID); Bill and Melinda... and other collaborators

Unknown

Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn

Sepsis | Infant, Newborn, Diseases | Puerperal Infection

South Africa
Yale-NUS College

Completed

Predictors of Success Following Bariatric Surgery

Focus of Study is Patient Responses to an Obesity Management Questionnaire Administered by SGH Life Centre

Singapore
Denver Health and Hospital Authority
National Institutes of Health (NIH)

Recruiting

Micro and Macro Circulation in Sepsis (DAISY)

Sepsis | Septic Shock

United States
Children's Hospital of Fudan University
Shanghai Children's Hospital; Shanghai Children's Medical Center; Xinhua Hospital...

Recruiting

Clinical Features and Outcomes of CBP Versus Non-CBP in Septic Children

Sepsis | Children, Only

China
Vanderbilt University Medical Center

Enrolling by invitation

Defining the Temporal Changes in the Acute Phase Response During Graded Exercise: A Prospective Study

Acute Phase Response

United States
Immunexpress
Rush University Medical Center; University of Southern California; Grady Memorial...

Completed

Near Patient Molecular Testing in Sepsis (NEPTUNE)

Sepsis | Systemic Inflammatory Response Syndrome

United States
University of British Columbia
Kenya Medical Research Institute

Completed

Paediatric Rapid Sepsis Trigger (PRST) Tool (PRST)

Sepsis | Infection

Uganda, Kenya
Guangdong Provincial Hospital of Traditional Chinese...

Completed

The Efficacy of Si-Ni-Tang (a Chinese Herbal Formula) for Severe Sepsis

Severe Sepsis

China
Phillip Brian Smith

Completed

Pharmacokinetics (PK) of Antistaphylococcal Antibiotics in Infants (NICHD-2012-02-Staph Trio) (Staph)

Systemic Infection

United States
Hospices Civils de Lyon

Completed

Study of the Combined Influence of Sepsis and Mechanical Ventilation on the Human Diaphragm (SEPTIC)

Respiration, Artificial

France
University Hospital Ostrava
Public Health Institute Ostrava

Completed

Presepsin in the Diagnosis of Sepsis in Critically Ill Patients

Sepsis | Infection

Czechia
Ain Shams University

Completed

Ultrasound-Assessed Diaphragmatic Dysfunction as a Predictor of Weaning Outcome

Sepsis | Weaning Failure

Egypt
Accelerate Diagnostics, Inc.

Active, not recruiting

Genotypic Versus Phenotypic Susceptibility Testing of Positive Blood Cultures

Bloodstream Infection

United States

Clinical Trials on Immune Responses

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Medical Conditions

Drug Interventions

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CROs in Ethiopia

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Rare Diseases

Drug Interventions

Dietary Supplements

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