Clinical Trials on Immunologic Deficiency Syndromes

Total 37157 results

Yale University
Bristol-Myers Squibb; Merck Sharp & Dohme LLC

Completed

Pilot Study of a Raltegravir Based NRTI Sparing Regimen

HIV Infections | Human Immunodeficiency Virus | AIDS | Acquired Immune Deficiency Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency

DOCK8 Deficiency

United States
Janssen Sciences Ireland UC

Completed

A Study to Evaluate Efficacy and Safety of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed Dose Combination (FDC) Versus a Regimen Consisting of Darunavir/Cobicistat FDC With Emtricitabine/Tenofovir Disoproxil Fumarate FDC in Treatment-naive HIV Type 1 Infected Subjects

Immunodeficiency Virus Type 1, Human

United States, France, Poland, United Kingdom, Belgium, Germany, Spain, Canada, Russian Federation, Puerto Rico
University of Zurich

Recruiting

Identification of New Inborn Errors of Immunity

Primary Immune Deficiency Disorder

Switzerland
National Institute of Allergy and Infectious Diseases...

Recruiting

Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

Primary Immune Deficiency

United States, Turkey
Octapharma

Completed

Study to Monitor Subcutaneous Human Immunoglobulin Administered at Modified Dosing Regimens in Patients With Primary Immunodeficiency Diseases

Primary Immune Deficiency Disorder

United States
Octapharma

Completed

Study of Octanorm Subcutaneous IG in Patients With PID

Primary Immune Deficiency Disorder

United States, Canada, Czechia, Hungary, Poland, Russian Federation, Slovakia
Assistance Publique - Hôpitaux de Paris

Completed

Primitive Immunodeficiency and Pregnancy (PREPI)

Primary Immune Deficiency

France
FFF Enterprises
OMRIX Biopharmaceuticals

Completed

A Clinical Study of Intravenous Immunoglobulin (IGIV)

Immunologic Deficiency Syndromes

United States, Canada
Qu Biologics Inc.
The National Research Council of Canada Industrial Research Assistance Program

Active, not recruiting

Assessment of QBKPN Site-Specific Immunomodulator Efficacy in Improving Innate Immune Function & Reducing Respiratory Tract Infection Morbidity in Older Adults (RESILIENCE)

Immune Deficiency

Canada
University Hospital, Caen

Completed

Intensive Care Unit and Secondary and Primary Immune Deficiency (ICUSPID)

Primary Immune Deficiency Disorder

France
CSL Limited

Completed

Ig NextGen 10% in Patients With Primary Immune Deficiency (PID)

Primary Immune Deficiency (PID)

Australia
University of Zurich

Recruiting

Pathophysiology of Inborn Immunodeficiencies

Primary Immune Deficiency Disorder

Switzerland
National Institute of Allergy and Infectious Diseases...

Terminated

Antibody Production in Immune Disorders

Primary Immune Deficiency

United States
Green Cross Corporation

Withdrawn

Study of Immune Globulin Intravenous (Human) GC5101F in Subjects With Primary Humoral Immunodeficiency

Primary Immune Deficiency Disorder
Kuwait Society for Allergy and Clinical Immunology

Completed

Primary Immunodeficiency in Kuwait

Primary Immune Deficiency Disorder

Kuwait
Karolinska University Hospital

Completed

Study of Vitamin D3 Substitution to Patients With Primary Immunodeficiency (VITAPID)

Primary Immune Deficiency Disorder

Sweden
Caja Costarricense de Seguro Social

Completed

Primary Immunodeficiencies in Costa Rican Adults

Primary Immune Deficiency in Adults

Costa Rica
Octapharma

Completed

Study to Evaluate the Efficacy, Tolerability and Safety of Octanorm in Patients With Primary Immunodeficiency Diseases

Primary Immune Deficiency Disorder

Russian Federation
CSL Behring

Completed

Follow-up Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (Japan Study)

Primary Immune Deficiency Disorder

Japan
UConn Health

Completed

Vaccination Efficacy With Metformin in Older Adults (VEME)

Aging | Vaccine Response Impaired | Age-Related Immunodeficiency

United States
ADMA Biologics, Inc.

Completed

Study to Evaluate Safety and Pharmacokinetics of BIVIGAM® in Primary Immune Deficiency Subjects Aged 2 to 16

Humoral Immune Response

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Effect of Ranitidine on Hyper-IgE Recurrent Infection (Job's) Syndrome

Immune Deficiency | JOB's Syndrome | Hyper-IgE Recurrent Infection Syndrome

United States
Octapharma

Completed

Octagam 5% Versus Comparator Post Marketing Trial

Primary Immune Deficiency Disorder

United States
ADMA Biologics, Inc.

Completed

Pharmacokinetics, Efficacy, and Safety Study of RI-002 (IGIV) in Subjects With Primary Immunodeficiency Diseases (PIDD)

Primary Immune Deficiency Disorder

United States
Ajou University School of Medicine

Unknown

IVIG Treatment for Asthmatic Patients With IgG Subclass Deficiency (IVIG)

Asthma
Therapure Biopharma Inc

Unknown

Study of PlasmaCap IG in Adults and Children With PIDD

Primary Immune Deficiency Diseases (PIDD)

United States, Canada
Sandoz

Completed

A Multicenter Placebo-Controlled Dose Titration Study to Evaluate the Efficacy and Safety of Sandostatin (SMS 201-995) in the Treatment of Patients With Acquired Immunodeficiency Related Diarrhea

HIV Infections | Diarrhea

United States
Sandoz

Completed

A Multicenter Placebo-Controlled Double Blind Study to Evaluate the Efficacy and Safety of Sandostatin ( SMS 201-995 ) in Patients With Acquired Immunodeficiency Related Diarrhea Who Were Either "Responders" or "Non-Responders" in a Prior Placebo-Controlled Double-Blind Sandostatin Study.

HIV Infections | Diarrhea

United States
ADMA Biologics, Inc.

Recruiting

An Open Label, Multicenter Study to Evaluate the Pharmacokinetics, Efficacy and Safety of ASCENIV™ (IGIV) in Pediatric Subjects With Primary Immunodeficiency Diseases (PIDD)

Primary Immune Deficiency

United States
Octapharma

Recruiting

Study to Evaluate the Pharmacokinetics, Efficacy, Tolerability, and Safety of Subcutaneous Human Immunoglobulin (Newnorm) in Patients With Primary Immunodeficiency Diseases

Primary Immune Deficiency

United States, Germany, Italy, Poland, Slovakia, Ukraine, Hungary
Imagine Institute
Assistance Publique - Hôpitaux de Paris

Completed

Evaluation of the Efficacy of the Sequencing Method by Gene-panel (Génétique-DIH)

Primary Immuno-Deficiencies

France
ADMA Biologics, Inc.

Completed

Open Label, Phase III Study of NABI-IGIV 10% [Immune Globulin Intravenous(Human), 10%] In Subjects With Primary Immune Deficiency Disorders (PIDD)

Primary Immune Deficiency Disorders (PIDD)

United States
GWT-TUD GmbH

Completed

Facilitated Immunoglobulin Administration Registry and Outcomes Study (FIGARO) (FIGARO)

Primary Immunodeficiency | Secondary Immune Deficiency

Germany, Italy, France
University of South Florida

Unknown

Evaluate Bacteriophage as a Useful Immunogen in Patients With Primary Immune Deficiency Diseases (PIDD) (Bacteriophage)

Primary Immune Deficiency Diseases

United States
Shanghai Children's Medical Center

Unknown

NFIL3-induced Pathological Enhancement of IgE Class Switch Recombination in Hyper-IgE Syndrome

Job Syndrome
Federal Research Institute of Pediatric Hematology...

Completed

TCR Alpha/Beta Depletion for HSCT From Haploidentical and Unrelated Donors in the Treatment of PID

Primary Immune Deficiency Disorder | Hematopoietic Stem Cell Transplantation

Russian Federation
University of Sao Paulo

Completed

Lymphocyte Count as a Sign of Immunoparalysis and Its Correlation With Nutritional Status in Septic Pediatric Patients

Lymphopenia
Oslo University Hospital

Completed

The Rifaximin Study in CVID

Common Variable Immunodeficiency (CVID)

Norway
Oswaldo Cruz Foundation

Unknown

Prospective Evaluation of HIV Patients Using Non-invasive Methods for Estimation of Liver Fibrosis and Steatosis (Prospec-HIV)

Liver Diseases | Fibrosis | Liver Cirrhosis | Human Immunodeficiency Virus | Acquired Immune Deficiency Syndrome Virus

Brazil
Universitaire Ziekenhuizen KU Leuven

Completed

Comparison of Multigam IV (5% vs. 10%) in Patients With an Immunodeficiency Secondary to a Hematological Disorder (MULTISIM)

Hematologic Diseases | Secondary Immune Deficiency

Belgium
University Hospital, Caen

Unknown

ENCAPSID Study : ENCApsulated Bacterial Infection and Primary, Secondary ImmunoDeficiency (ENCAPSID)

Immune Deficiency

France
Assistance Publique Hopitaux De Marseille

Unknown

Determinants of Health Status and Quality of Life in Patients With Primary Immunodeficiencies Inhereted Diagnosed During Childhood (CEREDIH)

Primary Immune Deficiency

France
Grifols Therapeutics LLC

Completed

Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency Patients

Common Variable Immunodeficiency | Severe Combined Immunodeficiency | Wiskott-Aldrich Syndrome | Agammaglobulinemia | Immunologic Deficiency Syndrome

Canada, United States
TRPHARM

Enrolling by invitation

Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E

Adenosine Deaminase Deficiency

Turkey
CSL Behring

Completed

Multicenter Study of Long-Term Clinical Outcomes of Subcutaneous Immune Globulin IgPro20 in Subjects With Primary Immunodeficiency (Japan Study)

Primary Immune Deficiency

Japan
ADMA Biologics, Inc.

Active, not recruiting

A Study About Low Blood Pressure in Patients With Primary Immunodeficiency Disease Treated With Immune Globulin Products

Primary Immune Deficiency Disorder

United States
University of South Florida
Merck Sharp & Dohme LLC

Terminated

Assessment of Immunogenicity of Zostavax® in Patients With Antibody Deficiency 60 Years of Age and Older

X-linked Agammaglobulinemia | Specific Antibody Deficiency | Common Variable Immune Deficiency

United States
Columbia University
Clínica de Familia La Romana, Dominican Republic

Recruiting

WiseApp for Spanish Speakers Living With HIV

HIV Infections | Sexually Transmitted Diseases, Viral | Acquired Immune Deficiency Syndrome

United States, Dominican Republic
Assistance Publique - Hôpitaux de Paris

Recruiting

Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE) (ARTEGENE)

Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency

France

Clinical Trials on Immunologic Deficiency Syndromes

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CROs in Costa Rica

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