Clinical Trials on Immunologic Activity Alteration

Total 7436 results

ViiV Healthcare
GlaxoSmithKline

Completed

An Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK1265744 Administered as a Single Oral Dose and a Study to Describe the Pharmacokinetics of a Supratherapeutic Dose of GSK1265744 in Healthy Adult Subjects

HIV-associated Lipodystrophy Syndrome

United States
University of Washington
GlaxoSmithKline; Asociación Civil Impacta Salud y Educación, Peru

Completed

HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1, HSV-2 Co-infected Men.

HIV Infection | Sexually Transmitted Diseases | Herpes Simplex

Peru
University of California, Los Angeles

Unknown

A Study Comparing Long-acting Methylphenidate (ConcertaTM) vs. Placebo in the Treatment of Memory Loss Due to HIV

HIV Dementia

United States
National Institute of Allergy and Infectious Diseases...

Completed

Fluconazole Prophylaxis of Thrush in AIDS

Acquired Immunodeficiency Syndrome | Candidiasis | Oral Candidiasis

United States
French National Agency for Research on AIDS and...
Hoffmann-La Roche

Terminated

Rituximab in the Treatment of HIV Associated Multicentric Castleman Disease Dependent on Chemotherapy

HIV Infections | Giant Lymph Node Hyperplasia
French National Agency for Research on AIDS and...

Completed

Randomised Controlled Trial Assessing the Impact of Genital Herpes Suppressive Therapy on HIV Shedding

HIV Infection | Herpes Genitalis

Burkina Faso
French National Agency for Research on AIDS and...

Terminated

Study Evaluating the Impact on Fat Distribution of Nucleoside Reverse Transcriptase Inhibitor (NRTI)-Sparing Regimens in Antiretroviral Experienced Patients With Lipoatrophy

HIV Infections | HIV Lipodystrophy Syndrome

France
Amgen

Completed

A Randomized, Controlled, Multicenter Trial of Filgrastim (Recombinant-Methionyl Human Granulocyte Colony Stimulating Factor; G-CSF) for the Prevention of Grade 4 Neutropenia in Patients With HIV Infection.

HIV Infections | Cytopenias

United States, Canada
Baylor College of Medicine
London School of Hygiene and Tropical Medicine; Centers for Disease Control... and other collaborators

Recruiting

Closing -TB GAPs - for People Living With HIV: TB Guidance for Adaptable Patient-Centered Service (TB_GAPS)

Tuberculosis | HIV Coinfection | Tuberculosis Infection

Swaziland
New York University
National Institutes of Health (NIH)

Recruiting

Symptom Management Efficacy Study to Reduce Distal Neuropathic Pain

Pain | HIV/AIDS | Neuropathic Pain | HIV Neuropathy

United States
University of California, San Francisco
Massachusetts General Hospital

Recruiting

Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study) (EPIC-HIV)

Cardiovascular Diseases | HIV Infections | Dyslipidemias

United States
National Institute of Allergy and Infectious Diseases...
Albert Einstein College of Medicine

Recruiting

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

Infections | Immune System Diseases | Pneumonia | Job Syndrome | STAT3 Transcription Factor

United States
National Human Genome Research Institute (NHGRI)

Active, not recruiting

Molecular and Clinical Studies of Primary Immunodeficiency Diseases

Wiskott- Aldrich Syndrome | ADA Deficient SCID

United States
Tuberculosis Research Centre, India
United States Agency for International Development (USAID)

Completed

Preventive Therapy for Tuberculosis in HIV Infected Persons

Tuberculosis | Human Immunodeficiency Virus

India
University College, London
London School of Hygiene and Tropical Medicine; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Active, not recruiting

Long-Acting Treatment in Adolescents (LATA) (LATA)

HIV Infections | Hiv | HIV-1-infection | Paediatric Human Immunodeficiency Virus Infection

Uganda, Zimbabwe, Kenya, South Africa
University of Pennsylvania
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

A Savings Intervention to Reduce Men's Engagement in HIV Risk Behaviors

Alcohol Consumption | Human Immunodeficiency Virus | Behavior | STI | Incentives

Kenya
Gilead Sciences

Terminated

Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels

Human Immunodeficiency Virus Type 1 (HIV-1) Infection

United States
National Institute of Allergy and Infectious Diseases...

Withdrawn

Natural History of Intestinal Inflammation in People With Primary Immune Dysregulations

Chronic Granulomatous Disease | Inflammatory Bowel Disease

United States
Massachusetts General Hospital
National Institute of Mental Health (NIMH); Match Research

Completed

Support for Perinatal Adherence and Depression (INSPireD)

Depression | Human Immunodeficiency Virus

United States, South Africa
National Institute of Allergy and Infectious Diseases...

Withdrawn

Treatment of Hepatitis in Patients Who Are Triple-Infected With HIV, Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV)

HIV Infections | Hepatitis B | Hepatitis C
Institute for Human Genetics and Biochemistry
CSL Behring

Completed

Therapy to Elevate CD4 Counts in HIV-1 Disease

HIV Disease

United States
CSL Behring

Completed

A Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary Angioedema

Hereditary Angioedema Types I and II

United States, Spain, Australia, Canada, Czechia, Hungary, Israel, Italy, Romania, United Kingdom
University of Pennsylvania

Completed

Downmodulating Monocyte Activation for HIV-1 Associated Neurocognitive Disorders (HAND)

HIV Dementia

United States
Drexel University

Completed

Addressing Overdose Risk Among Recently Incarcerated People Living With HIV/AIDS

Drug Overdose Accidental

United States
Dallas VA Medical Center
Merck Sharp & Dohme LLC

Terminated

Impact of Hepatitis C Therapy and Bone Health (HCV)

Hepatitis C | Human Immunodeficiency Virus

United States
ViiV Healthcare
GlaxoSmithKline; Shionogi

Completed

GSK1349572 Hepatic Impairment Study

HIV Infections | Healthy Subjects | Hepatic Impairment | Infection, Human Immunodeficiency Virus

United States
Bruce Brew
ViiV Healthcare

Completed

A Study of the Neurological Effects of Adding Maraviroc to HAART Regimen in Patients With HIV (HANDmac) (HANDmac)

Human Immunodeficiency Virus (HIV) | HIV Associated Neurocognitive Disorders (HAND)

Australia
Emory University

Completed

Bone Loss and Immune Reconstitution in HIV/AIDS (BLIR-HIV) (BLIR-HIV)

HIV Infection | Osteoporosis | Bone Loss | Osteopenia

United States
University of Hawaii
Oregon Health and Science University

Completed

Ferumoxytol-enhanced Brain MRI in HIV-associated Neurocognitive Disorders

HIV Dementia

United States
National Institutes of Health Clinical Center (CC)

Completed

Evaluation of Brain Lesions in HIV-infected Patients for Diagnosis of Primary Central Nervous System Lymphoma

HIV Infections | Lymphoma, AIDS-Related

United States
O & O Alpan LLC

Unknown

Investigation of Immune Disorders and Deficiencies

Autoimmune Diseases | Hypogammaglobulinemia | Inflammatory Diseases | Primary Immune Deficiencies | Common Variable Immune Deficiencies

United States
Lin, Hsi-Hsun, M.D.

Completed

Sustained Virological Suppression and Improvement of Adverse Events of Switching to Raltegravir Study (TaISENWITCH)

HIV Infection | Quality of Life | Adverse Drug Reaction

Taiwan
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Retrovirus Epidemiology Donor Study I (REDS I)

HIV Infections | Acquired Immunodeficiency Syndrome | Retroviridae Infections | Blood Transfusion | HIV-1 | Blood Donors | HIV-2 | HTLV-I | HTLV-II
Emory University
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Effect of HIV Infection and Highly Active Antiretroviral Treatment (HAART) on Bone Homeostasis (OPG-2)

HIV Infection | Osteoporosis | Osteopenia

United States
Johns Hopkins University
The New York Academy of Medicine

Completed

Comparison of HIV Clinic-based Treatment With Buprenorphine Versus Referred Care in Heroin-dependent Participants

HIV Infections | HIV Seropositivity | Opiate Dependence

United States
Columbia University
National Institute of Allergy and Infectious Diseases (NIAID); GlaxoSmithKline

Completed

Mupirocin Ointment to Eliminate Nasal Carriage of Staphylococcus Aureus in HIV Infection

HIV Infections | Staphylococcus Aureus

United States
University Hospital, Catania

Unknown

Hereditary AngioEdema, Neurobiology and Psychopathology (HAENP)

Depression | Anxiety | Hereditary AngioEdema

Italy
Emory University
Makerere University

Completed

Differences in Response to the Flu Vaccine Among Adults With HIV and Without HIV in Uganda

Acquired Immunodeficiency Syndrome | HIV | Influenza

Uganda
EMD Serono

Completed

An Efficacy and Safety Trial of Serostim® in the Maintenance of the Treatment Effect Obtained During the Study of Serostim® in Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome

Human Immunodeficiency Virus Infections | Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome (HARS)
National Institute of Allergy and Infectious Diseases...

Completed

Nerve Damage in Patients With HIV Infection Who Have Been Treated With Anti-HIV Drugs

HIV Infections | Peripheral Nervous System Disease

United States
French National Agency for Research on AIDS and...

Completed

Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africa

HIV Infections | Tuberculosis

South Africa
Bristol-Myers Squibb

Completed

Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome

HIV-Associated Lipodystrophy Syndrome

Spain, Italy, United States, Canada, France, Mexico, United Kingdom, Poland, Germany
University Hospital, Geneva

Completed

Vaccine Responses to Influenza A H1N1/09 Immunization in High-risk Patients

HIV Infection | Cancer | Transplant | Pediatrics | Rheumatic Disease

Switzerland
National Institute of Diabetes and Digestive and...

Completed

AIDS Wasting in Women: Anabolic Effects of Testosterone

AIDS Wasting Syndrome

United States
Astra USA

Completed

An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies

HIV Infections | Herpes Simplex

United States
Celgene Corporation

Completed

Compassionate Use Study of Two Dose Levels of Thalidomide in Adults With HIV Wasting Syndrome

HIV Infections | HIV Wasting Syndrome

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID); Rockefeller...

Completed

Phase II Placebo Controlled Study of Thalidomide in Patients With Mycobacterial and HIV Infections

HIV Infections | Mycobacterium Infections | Tuberculosis
University Hospital Hradec Kralove
American Association for Thoracic Surgery

Recruiting

AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis (AOSIS)

Infections | Systemic Inflammatory Response Syndrome | Immunological Abnormality | Aortic Diseases | Thoracic Aortic Aneurysm

Czechia
Wuhan Union Hospital, China

Not yet recruiting

Combination Therapy of HAIC, Surufatinib and Tislelizumab for Unresectable or Metastatic Biliary Tract Cancer

Carcinoma | Intrahepatic Cholangiocarcinoma | Gallbladder Cancer | Immunotherapy | Tislelizumab | Surufatinib | Angiogenesis Inhibitors | Antineoplastic Agents, Immunological
Foundation for Liver Research

Completed

Study Investigating Immunological Effects of Treatment for Chronic Hepatitis C Patients. (CIRES)

Hepatitis C | Immunology | Liver | Regulation

Netherlands

Clinical Trials on Immunologic Activity Alteration

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in South Africa

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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