Clinical Trials on Immunologic Disorders

Total 148926 results

National Institute of Allergy and Infectious Diseases...

Recruiting

Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD)

Chronic Granulomatous Disease | CGD

United States
Sanguine Biosciences

Terminated

Whole Blood Biospecimen Collection for Subjects With Chronic Granulomatous Disease (CGD)

Chronic Granulomatous Disease

United States
Genethon

Active, not recruiting

Gene Therapy for X-linked Chronic Granulomatous Disease (X-CGD) (CGD)

X-Linked Chronic Granulomatous Disease

United Kingdom
Advanced Neurosciences Institute
Novel Pharmaceutics Institute

Unknown

Immunodeficiency in MS

Multiple Sclerosis | Infection, Bacterial | Immunodeficiency | Hypogammaglobulinemia

United States
University of California, San Francisco

Completed

Project RAP: Family-based HIV Prevention in the Juvenile Drug Court (Project RAP)

HIV/AIDS

United States
Fundacion SEIMC-GESIDA

Completed

A Phase IV, Open-label, Randomised, Pilot Clinical Trial Designed to Evaluate the Potential Neurotoxicity of Dolutegravir/Lamivudine/Abacavir in Neurosymptomatic HIV Patients and Its Reversibility After Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide. DREAM Study (DREAM)

HIV Infections

Spain
Brigham and Women's Hospital

Completed

Personalized Immunotherapeutic for Antibiotic-resistant Infection

Infection | Immune Deficiency | Hypogammaglobulinemia | Septic Arthritis | Mycoplasma Hominis

United States
University of South Florida
Johns Hopkins University; Baylor College of Medicine; Boston Children's Hospital and other collaborators

Completed

Construction of a Health-related Quality of Life (HR-QOL) Questionnaire for Patients With Primary Antibody Deficiency Disease (HR-QOLPIDD)

Immune Deficiency, Antibody
National Institute of Allergy and Infectious Diseases...

Completed

A Study of HIV in Newly Infected Individuals

HIV Infections

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Donor Stem Cell Transplant in Treating Young Patients With Myelodysplastic Syndrome, Leukemia, Bone Marrow Failure Syndrome, or Severe Immunodeficiency Disease

Myelodysplastic Syndromes | Leukemia | Congenital Amegakaryocytic Thrombocytopenia | Severe Congenital Neutropenia

United States
University of California, San Francisco

Completed

Newborn Screening for Severe Combined Immunodeficiency (SCID) in a High-Risk Population

Severe Combined Immunodeficiency | T Cell Lymphocytopenia

United States
Sandoz

Completed

A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia

HIV Infections | Cytopenias

United States
National Human Genome Research Institute (NHGRI)

Active, not recruiting

Molecular and Clinical Studies of Primary Immunodeficiency Diseases

Wiskott- Aldrich Syndrome | ADA Deficient SCID

United States
Drexel University

Completed

Addressing Overdose Risk Among Recently Incarcerated People Living With HIV/AIDS

Drug Overdose Accidental

United States
Bruce Brew
ViiV Healthcare

Completed

A Study of the Neurological Effects of Adding Maraviroc to HAART Regimen in Patients With HIV (HANDmac) (HANDmac)

Human Immunodeficiency Virus (HIV) | HIV Associated Neurocognitive Disorders (HAND)

Australia
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Miami; Weill Medical College... and other collaborators

Recruiting

Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

Alcohol-Related Disorders | Substance Use | Drug Use | Human Immunodeficiency Virus

South Africa
Lin Chen

Completed

Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes

Sepsis | Cytokine Storm | Sympathetic Nervous System Diseases | Catecholamine; Overproduction | Immunologic Paralysis | Lymphocyte Disorder T | Beta-Blocker

China
National Institute of Allergy and Infectious Diseases...

Recruiting

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

Chronic Granulomatous Disease

United States
Fundacion SEIMC-GESIDA
Janssen-Cilag, S.A.

Completed

A Clinical Trial to Evaluate the Reversibility of Abacavir/Lamivudine/Dolutegravir CNS-Related Neurotoxicity After Switching to Tenofovir/Alafenamide/Emtricitabine/Darunavir/Cobicistat (TAF/FTC/DRV/c) (DETOX)

HIV Infections

Spain
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Azidothymidine Plus Methadone in Patients With AIDS and AIDS Related Complex (ARC)

HIV Infections

United States
Yale University
National Institute of Mental Health (NIMH)

Not yet recruiting

The Dreamer Girls Project: Adaptation of SISTA/SIHLE for HIV/AIDS and Substance Abuse Prevention Among Black Adolescent Girls

HIV/AIDS

United States
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Alcohol Pharmacotherapy for HIV+ Prisoners (INSPIRE)

Alcohol Dependence | Human Immunodeficiency Virus | AIDS | Hazardous Drinking | Problem Drinking

United States
VA Connecticut Healthcare System
Yale University

Withdrawn

Pharmacotherapy for HIV Infected Patients With Alcohol Problems

HIV Infections | HIV Infection | Heavy Alcoholic Consumption
St Vincent's Hospital, Sydney
Merck Sharp & Dohme LLC

Terminated

A Study of the Neurological Effects of Adding Raltegravir to HAART Regimen in Patients With HIV (HANDral)

Human Immunodeficiency Virus (HIV) | HIV Associated Neurocognitive Disorders (HAND)

Australia
Octapharma

Completed

CLINICAL PHASE III STUDY TO MONITOR THE SAFETY, TOLERABILITY AND EFFICACY OF SUBCUTANEOUS HUMAN IMMUNOGLOBULIN (OCTANORM) IN PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISEASES, INCLUDING (BUT NOT LIMITED TO) THOSE WHO HAVE COMPLETED THE SCGAM-01 TRIAL

Primary Immunodeficiency

United States, Canada
Assiut University

Completed

Minipooled-IVIG in Primary Immunodeficiency Disease

Primary Immunodeficiency

Egypt
CSL Behring

Completed

Safety and Tolerability of Higher Infusion Parameters of IgPro20 (Hizentra) in Subjects With Primary Immunodeficiency (PID)

Primary Immunodeficiency

United States, Canada
University Hospital, Lille

Completed

Evolution of Interleukin 7, Fat Mass and Metabolic Profile Before and After Transplantation (IL-7tran)

Immunodeficiency Secondary to Organ Transplantation

France
IMMUNOe Research Centers

Completed

The Benefit of 5% IVIG for Patients With Primary Immunodeficiency Disorders Who Experience Adverse Events on 10% IVIG Preparations

Primary Immunodeficiency
Grifols Therapeutics LLC

Completed

Pharmacokinetics, Safety, and Tolerability of Subcutaneous GAMUNEX-C in Pediatric Subjects With Primary Immunodeficiency (KIDS)

Primary Immunodeficiency

United States
University of Houston
National Institute on Drug Abuse (NIDA)

Completed

Project PRIDE (Promoting Resilience In Discriminatory Environments)

Depression | Anxiety | Substance Use Disorders | Sexually Transmitted Infections | Human Immunodeficiency Virus

United States
CES University
IPS Fundación SIAM

Unknown

Zinc Supplementation Effect on Immune Recovery in HIV Patients

HIV | AIDS | Immunological Deficiency | Inadequate Immune Recovery | Viral Replication

Colombia
Gazi University

Recruiting

Investigation of the Effects of Pulmonary Rehabilitation in Children With Primary Immunodeficiency

Primary Immunodeficiency

Turkey
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Composition and Function of Gut Microbiota in Porto-sinusoidal Vascular Disease Associated With Variable Common Immunodeficiency (MI-MVPS)

Vascular Diseases | Common Variable Immunodeficiency

France
Grifols Therapeutics LLC

Completed

A Study to Evaluate IGSC 20% Biweekly Dosing in Treatment-Experienced Participants and Loading/Maintenance Dosing in Treatment-Naïve Participants With Primary Immunodeficiency

Primary Immunodeficiency

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy of CDZ173 in Patients With APDS/PASLI

Common Variable Immunodeficiency (CVID), APDS / PASLI

Germany, Russian Federation, Ireland, Italy, United Kingdom, Belarus, Netherlands, Czechia, United States
Grifols Therapeutics LLC

Completed

Safety and Pharmacokinetics of IGSC 20% in Subjects With Primary Immunodeficiency

Primary Immunodeficiency

United States, Canada
Yale University
National Institute on Drug Abuse (NIDA); University of Malaya

Completed

Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia (Harapan)

Acquired Immunodeficiency Syndrome | Human Immunodeficiency Virus | Opiate Addiction | Drug Dependence
National Institutes of Health Clinical Center (CC)
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Brain Imaging for HIV-Associated Thinking and Mood Disorders

Human Immunodeficiency Virus | Neurocognitive Impairment

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Use of Memantine In Combination With Anti-HIV Drugs to Treat AIDS Dementia Complex (ADC)

HIV Infections | AIDS Dementia Complex

United States
Centaur Pharmaceuticals

Completed

Safety and Effectiveness of CPI-1189 in HIV-Infected Males on Combination Anti-HIV Drug Therapy

HIV Infections | AIDS Dementia Complex

United States
State University of Maringá
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Effect of Supplementation With Glutamine and Exercise in Women With HIV/AIDS

Physical Activity | Glutamine; Metabolic Disorder
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia Complex

HIV Infections | AIDS Dementia Complex

United States
University of Hawaii
ViiV Healthcare; University of Puerto Rico

Completed

Maraviroc and NeuroAIDS Pathogenesis

AIDS Dementia Complex

United States, Puerto Rico
Beau Nakamoto
National Institute of Neurological Disorders and Stroke (NINDS); University... and other collaborators

Completed

Ferumoxytol-enhanced Imaging and Mapping in neuroAIDS

AIDS Dementia Complex

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Use of Stavudine (d4T) to Treat AIDS Dementia Complex

HIV Infections | AIDS Dementia Complex

United States, Australia, United Kingdom
Glaxo Wellcome

Completed

A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex

HIV Infections | AIDS Dementia Complex

United States, Canada
National Institute of Allergy and Infectious Diseases...

Recruiting

Send-In Sample Collection to Achieve Genetic and Immunologic Characterization of Primary Immunodeficiencies

Primary Immunodeficiency

United States, Turkey, Italy
Prometic Biotherapeutics, Inc.
Atlantic Research Group

Completed

Study of ProMetic BioTherapeutics Immune Globulin Intravenous (Human) 10%

Primary Immunodeficiency

United States
Grifols Therapeutics LLC

Completed

Efficacy, Pharmacokinetics, Safety, and Tolerability of IGSC 20% in Subjects With Primary Immunodeficiency

Primary Immunodeficiency

Spain, France, Germany, United Kingdom, Australia, Czechia, Hungary, Poland, Sweden

Clinical Trials on Immunologic Disorders

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CROs in China

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