Clinical Trials on Immunosuppression Disorders

Total 144479 results

Memorial Sloan Kettering Cancer Center
Context Therapeutics Inc.

Active, not recruiting

A Study of Onapristone ER Alone Or In Combination With Anastrozole in Gynecologic Cancers That Respond to Progesterone

Granulosa Cell Ovarian Cancer | Low Grade Serous Ovarian/ Primary Peritoneal Cancer | Endometrioid Endometrial Cancer

United States
ImmunoGen, Inc.

Active, not recruiting

IMGN853 With Carboplatin in Second-line Treatment of FRα Expressing, Platinum-sensitive Epithelial Ovarian Cancer

Fallopian Tube Cancer | Primary Peritoneal Cancer | High Grade Ovarian Cancer

United States, United Kingdom, Belgium, Spain, Canada, Georgia
Hoffmann-La Roche

Active, not recruiting

An Interventional Study of Avastin (Bevacizumab) in Patients With Advanced/Metastatic Epithelial Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer

Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms

India
Vanderbilt University Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Brigham... and other collaborators

Suspended

Optimal Management of HIV Infected Adults at Risk for Kidney Complications in Nigeria

Kidney Diseases | HIV/AIDS | Albuminuria | Genetic Predisposition

Nigeria
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Prehabilitation Care for Women With Advanced Ovarian Cancer Receiving Neoadjuvant Chemotherapy

Ovarian Cancer | Fallopian Tube Cancer | Fallopian Tube Carcinoma | Primary Peritoneal Carcinoma | Stage IV Ovarian Cancer | Stage III Ovarian Cancer

United States
M.D. Anderson Cancer Center

Active, not recruiting

Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Recurrent Acute Myeloid Leukemia | Recurrent Chronic Myelomonocytic Leukemia | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Recurrent Myelodysplastic/Myeloproliferative Neoplasm | Refractory Myelodysplastic/Myeloproliferative Neoplasm

United States
SpringWorks Therapeutics, Inc.

Available

Individual Patient Compassionate Use of Mirdametinib

Neurofibromatosis Type 1-Associated Plexiform Neurofibromas | Histiocytic Neoplasm | Other MAP-K Pathway Driven Diseases
Verastem, Inc.
GOG Foundation; European Network of Gynaecological Oncological Trial Groups...

Active, not recruiting

A Study of Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer With and Without a KRAS Mutation (RAMP 201)

Ovarian Cancer | Low Grade Ovarian Serous Adenocarcinoma

Spain, United States, Belgium, United Kingdom, France, Canada, Italy
Intermountain Health Care, Inc.

Completed

Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure (IMPROVENT)

Severe Acute Respiratory Syndrome | Respiratory Insufficiency | Acute Respiratory Distress Syndrome | Respiratory Distress Syndrome | ARDS | Shock Lung | Respiratory Distress Syndrome, Acute

United States
Aprea Therapeutics

Completed

p53 Suppressor Activation in Recurrent High Grade Serous Ovarian Cancer, a Phase Ib/II Study of Systemic Carboplatin Combination Chemotherapy With or Without APR-246

Platinum Sensitive Recurrent High-grade Serous Ovarian Cancer With Mutated p53

United States, France, Spain, Netherlands, United Kingdom, Belgium, Germany, Sweden
University of Nottingham

Completed

Monitoring of Inflammatory Conditions

Rheumatoid Arthritis | Psoriasis | Crohn Disease | Inflammatory Arthritis | Ulcerative Colitis | Psoriatic Arthritis | Reactive Arthritis | Inflammatory Disease | System; Lupus Erythematosus

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Watchful Living in Improving Quality of Life in Participants With Localized Prostate Cancer on Active Surveillance and Their Partners

Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IIA Prostate Cancer AJCC v8 | Stage IIB Prostate...

United States
BeiGene

Completed

Study of the Efficacy, Safety and Pharmacokinetics of Pamiparib (BGB-290) in Participants With Advanced Solid Tumors

Triple Negative Breast Cancer | Advanced High-grade Ovarian Cancer

China
Erasme University Hospital

Completed

Chemical and Mechanical Angioplasty for Vasospasm (SAVEBRAIN) (SAVEBRAIN)

Arteriovenous Fistula | Aneurysmal Subarachnoid Hemorrhage | Vasospasm, Intracranial | Stenosis | Ruptured Cerebral Aneurysm | Arteriovenous Malformations, Cerebral

Belgium
Memorial Sloan Kettering Cancer Center
Harvard University; Broad Institute

Active, not recruiting

Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes

Lynch Syndrome | Hereditary Colonic Polyposis Syndromes

United States
Nantes University Hospital
Istituto Giannina Gaslini; Pediatric Intensive Care Unit, Trousseau University... and other collaborators

Completed

Cerebral Autoregulation in Pediatric ECMO (ECMOX 2) (ECMO-ECMOX2)

Cardiac Arrest | Cardiogenic Shock | Acute Respiratory Distress Syndrome (ARDS)

France, Italy
Sarcoma Alliance for Research through Collaboration
United States Department of Defense; AstraZeneca

Completed

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Neurofibromatosis 1 | Malignant Peripheral Nerve Sheath Tumors

United States
Tisento Therapeutics
Children's Hospital of Philadelphia

Terminated

Phase 2a Study of IW-6463 in Adults Diagnosed With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS)

MELAS

United States
Regeneron Pharmaceuticals

Available

Compassionate Use of Dupilumab

Bullous Pemphigoid | Pediatric Asthma | Pediatric Eosinophilic Esophagitis (EoE) | Pediatric and Adolescent Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Leidos Life Sciences
United States Department of Defense

Withdrawn

Leidos-Enabled Adaptive Protocol for Clinical Trials (LEAP-CT) in Hospitalized Patients With COVID-19 (Addendum 1)

COVID-19 | Covid19 | Coronavirus Disease 2019 | SARS-CoV-2 Infection | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Pandemic | COVID-19 Virus Infection | COVID-19 Virus Disease | 2019 Novel Coronavirus Disease | 2019 Novel Coronavirus Infection | 2019-nCoV Disease | 2019-nCoV Infection
Canadian Cancer Trials Group
National Cancer Institute (NCI); Cancer Research UK; Grupo Español de Investigación... and other collaborators

Completed

Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cavity Cancer | Metastatic Cancer

Canada, Spain, United States, United Kingdom
University Hospital, Tours

Completed

French National Cohort of Children With Port Wine Stain (CONAPE)

Port Wine Stain | Parkes Weber Syndrome | Klippel Trenaunay Syndrome

France
University of Minnesota

Available

Islet Transplant for Type 1 or Surgical Diabetes (EXAX)

Hypoglycemia | Type 1 Diabetes Mellitus | End-stage Renal Disease | Labile Diabetes

United States
Bezmialem Vakif University

Completed

Anticoagulant/Antiaggregant Use and Postoperative Bleeding Risk in Patients With Bladder Tumor and Benign Prostatic Hyperplasia

Hematuria | Retention, Urinary | Operative Bleeding | Blood Transfusion Complication

Turkey
Rigshospitalet, Denmark
University of Copenhagen; Herlev Hospital; Steno Diabetes Center Copenhagen; Holbaek... and other collaborators

Active, not recruiting

Cardiac Arrhythmia in Patients With End-Stage Renal Disease (CADDY)

Diabetes Mellitus | Hypoglycemia | Cardiac Arrhythmia | End Stage Renal Disease on Dialysis

Denmark
EyePoint Pharmaceuticals, Inc.
Medical Technology Enterprise Consortium (MTEC)

Terminated

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 (RESCUE)

COVID-19 | Acute Respiratory Distress Syndrome (ARDS)

United States
University of Chicago

Active, not recruiting

Inhaled Nitric Oxide and Neuroprotection in Premature Infants (NOVA2)

Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Prematurity | Periventricular Leukomalacia

United States
Centre Hospitalier Universitaire de Nice

Completed

Frequency of Pompe's Disease and Neuromuscular Etiologies in Patients With Restrictive Respiratory Failure Associated With Signs of Muscle Weakness (POPS3)

Pompe Disease

France
WellSpan Health

Active, not recruiting

Frequency of Endometrial Cancer Precursors Associated With Lynch Syndrome

Endometrial Hyperplasia | Lynch Syndrome | Endometrial Cancer | Microsatellite Instability | Mismatch Repair Deficiency

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Farber Disease (BioFarber) (BioFarber)

Splenomegaly | Hepatomegaly | Ceramidase Deficiency | Farber's Lipogranulomatosis

Germany, India, Egypt
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Metachromatic Leukodystrophy (BioMeta) Disease (BioMeta)

Muscle Weakness | Peripheral Neuropathy

Egypt, Germany, India, Sri Lanka
Masonic Cancer Center, University of Minnesota

Active, not recruiting

Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19)

Acute Respiratory Distress Syndrome | COVID-19 Pneumonia | ARDS (Moderate or Severe)

United States
University of California, San Diego

Active, not recruiting

Biomarkers, Genomics, Physiology in Critically Ill and ECMO Patients (IGNITE)

Critical Illness | Respiratory Failure | Renal Failure | Acute Respiratory Distress Syndrome | Pulmonary Disease | Extracorporeal Membrane Oxygenation Complication | Cardiac Failure

United States
Dr. Jurjan Aman
Exvastat Ltd.; Simbec-Orion Group; KABS laboratories

Terminated

Intravenous Imatinib in Mechanically Ventilated COVID-19 Patients (INVENT COVID)

Covid19 | Endothelial Dysfunction | Acute Respiratory Distress Syndrome | ARDS | Pulmonary Edema

Netherlands
Rush University Medical Center
Icahn School of Medicine at Mount Sinai

Withdrawn

Telerobotic Ultrasound for Carotid Imaging - Feasibility Study

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Coronary Artery Disease | Stroke | Cerebrovascular Disorders | Coronary Disease | Arteriosclerosis | Arterial Occlusive Diseases | Cardiovascular Disease | Atherosclerosis | Peripheral Vascular Disease | Cerebral Infarction | Coronary Arteriosclerosis | Cerebrovascular... and other conditions
University Hospital, Grenoble

Completed

Detection of Right Ventricular Dysfunction by 2D Strain During Acute Respiratory Distress Syndrom (ARDS) (STRAIN)

Acute Respiratory Distress Syndrome | Right Ventricular Dysfunction | Right Heart Failure | Acute Cor Pulmonale

France
University of New Mexico

Completed

Stroke and Cerebrovascular Diseases Registry

Stroke | Ischemic Stroke | Transient Ischemic Attack | Cerebral Infarction | Subarachnoid Hemorrhage | Hemorrhagic Stroke | Acute Brain Injury | Acute Stroke | Cerebral Stroke | Cerebral Ischemia | Venous Sinus Thrombosis, Cranial

United States
Leidos Life Sciences
United States Department of Defense

Terminated

Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients (Addendum 2)

COVID-19 | Covid19 | Coronavirus Disease 2019 | SARS-CoV2 Infection | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Pandemic | COVID-19 Virus Infection | COVID-19 Virus Disease | 2019 Novel Coronavirus Disease | 2019 Novel Coronavirus Infection | 2019-nCoV Disease | 2019-nCoV Infection

United States
Nasser Hanna, M.D.
Merck Sharp & Dohme LLC; Hoosier Cancer Research Network

Terminated

Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors

Genital Neoplasms, Female | Testicular Neoplasms | Genital Neoplasms, Male | Ovarian Neoplasms | Mediastinal Neoplasms | Germ Cell Neoplasms | Non Seminomatous Germ Cell Tumors

United States
University of Minnesota

Completed

Losartan for Patients With COVID-19 Not Requiring Hospitalization

Acute Respiratory Distress Syndrome | Corona Virus Infection | SARS-CoV Infection

United States
Express Collaborative
Canadian Institutes of Health Research (CIHR); International Network for Simulation-based...

Completed

Impact of Aerosol Box Use on Healthcare Provider Contamination

Covid19 | Coronavirus | COVID-19 Acute Respiratory Distress Syndrome

United States, Canada
Agence Sanitaire et Sociale de Nouvelle Calédonie
Institut Pasteur; World Health Organization; Pacific Community; Institut de la...

Suspended

Baromètre Santé Adulte 2021-2022

Diabetes | Renal Failure | Chronic Disease | Hypercholesterolemia | Malaria | SARS-CoV Infection | Dengue Fever | Chikungunya | Zika | Ross River

New Caledonia
Idorsia Pharmaceuticals Ltd.

Completed

Natural History Study for Pediatric Patients With Early Onset of Either GM1 Gangliosidosis, GM2 Gangliosidoses, or Gaucher Disease Type 2 (RETRIEVE)

GM2 Gangliosidosis | GM1 Gangliosidosis | Tay-Sachs Disease | Sandhoff Disease | Gaucher Disease, Type 2 | AB Variant Gangliosidosis GM2

United States, Spain, Germany, Italy, Belgium, Brazil, France, Portugal, Switzerland, United Kingdom
Acticor Biotech

Completed

Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19 (GARDEN)

COVID-19 | Acute Respiratory Distress Syndrome | ARDS | SARS-CoV Infection

France
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Everolimus (Afinitor®) in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex.

Renal Angiomyolipoma

China
Mansoura University

Active, not recruiting

A Randomized Controlled Trial to Investigate The Role of Adjuvant Inhalable Sodium Bicarbonate Solution 8.4% in Treatment of COVID-19

Covid19 | COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome

Egypt
MaxCyte, Inc.
CTI Clinical Trial and Consulting Services

Terminated

Intraperitoneal MCY-M11 (Mesothelin-targeting CAR) for Treatment of Advanced Ovarian Cancer and Peritoneal Mesothelioma

Fallopian Tube Adenocarcinoma | Peritoneal Mesothelioma | Primary Peritoneal Carcinoma | Adenocarcinoma of the Ovary

United States
Centre Chirurgical Marie Lannelongue

Terminated

Dexamethasone Treatment for Severe Acute Respiratory Distress Syndrome Induced by COVID-19 (DHYSCO)

COVID-19 | Respiratory Distress Syndrome, Adult

France
Istanbul University

Completed

Effects of Low Molecular Weight Heparin Therapy With Soft-Mist Inhaler for COVID-19 Induced Hypoxemia

Hypoxemia | COVID-19 Acute Respiratory Distress Syndrome

Turkey
Rabin Medical Center

Terminated

Efficacy and Safety of Dipeptidyl Peptidase-4 Inhibitors in Diabetic Patients With Established COVID-19

Glucose Metabolism Disorders | Respiratory Tract Diseases | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Endocrine System Diseases | COVID 19 | Coronavirus | Metabolic Disease | Severe Acute Respiratory Syndrome Coronavirus 2 | Sars-CoV2 | Hormones | Hypoglycemic Agents | Incretins | Dipeptidyl-Peptidase IV Inhibitors and other conditions

Israel

Clinical Trials on Immunosuppression Disorders

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Medical Conditions

Drug Interventions

CROs by country

CROs in Iran

Conditions

Rare Diseases

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Dietary Supplements

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