Clinical Trials on Impairment

Total 3309 results

Baycrest

Completed

A Pilot Study for the Brain Health Support Program (CTU BHSP-P)

Dementia | Mild Cognitive Impairment | Dementia Prevention | Subjective Cognitive Impairment | Pre-dementia

Canada
Duke University
Alzheimer's Association; Duke-NUS Graduate Medical School; Duke Institute for...

Completed

Novel Retinal Imaging Biomarkers in Early Alzheimer's Disease

Mild Cognitive Impairment | Mild to Moderate Cognitive Impairment

United States
C2N Diagnostics

Recruiting

Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey (QUIP II)

Cognitive Impairment | Dementia | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline | Memory Impairment

United States
Taipei Veterans General Hospital, Taiwan
National Yang Ming Chiao Tung University

Recruiting

To Exam the Efficacy of Oral Health and Mediterranean Diet Interventions in Preventing Cognitive Decline Among Older Adults With Mild Cognitive Impairment

Mild Cognitive Impairment (MCI) | Oral Health | Mediterranean Diet

Taiwan
Clinique Rive Gauche

Completed

Highlighting the Benefits of a Screening Protocol Delivered by Orthoptists to Identify Visual Impairment in Children Aged 3 to 4 (ORTHOPHTALMO)

Visual Impairment in Children

France
Cerecin

Completed

Tricaprilin In Age-Associated Memory Impairment

Age-Associated Memory Impairment

United States
Allon Therapeutics

Completed

Safety, Tolerability and Efficacy Study to Evaluate Subjects With Mild Cognitive Impairment

Mild Cognitive Impairment, So Stated

United States
Loughborough University

Active, not recruiting

Dual-task Exercise in People With Cognitive Impairment

Dementia | Mild Cognitive Impairment | Older Adults

United Kingdom
Charite University, Berlin, Germany

Completed

Effects of Brain Stimulation During a Daytime Nap on Memory Consolidation in Patients With Mild Cognitive Impairment

Mild Cognitive Impairment, So Stated

Germany
Rochester Center for Behavioral Medicine
Shire

Completed

Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome

Chronic Fatigue Syndrome | Cognitive Impairments

United States
University of Southern California
National Institute on Aging (NIA); Northern California Institute of Research... and other collaborators

Completed

Alzheimer's Disease Neuroimaging Initiative 2 (ADNI2)

Mild Cognitive Impairment (MCI) | Alzheimer's Disease (AD) | Significant Memory Concern (SMC) | Early Mild Cognitive Impairment (EMCI) | Late Mild Cognitive Impairment (LMCI)

United States, Canada
Jewish General Hospital

Active, not recruiting

Effects of Montreal Museum of Fine Arts Visits and Older Community Dwellers With a Precarious State

Old Age | Well Aging | Social Isolation | Health Impairment

Canada
Charite University, Berlin, Germany

Withdrawn

Effects of Brain Stimulation During Nocturnal Sleep on Memory Consolidation in Patients With Mild Cognitive Impairments

Mild Cognitive Impairment, So Stated

Germany
Sichuan Haisco Pharmaceutical Group Co., Ltd
The First Affiliated Hospital of Zhengzhou University

Completed

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Impairment Renal Functions

Chronic Renal Impairment

China
Enzymotec

Completed

The Efficacy of Phosphatidylserine-Omega3 in Elderly With Age Associated Memory Impairment

Age Associated Memory Impairment

Israel
Chong Kun Dang Pharmaceutical
Choline Alfoscerate Re-evaluation Consortium (57 pharmaceutical companies)

Not yet recruiting

A Clinical Trial to Evaluate the Efficacy and Safety of Choline Alfoscerate in Vascular Cognitive Impairment Patients

Vascular Cognitive Impairment

Korea, Republic of
King's College London

Unknown

White Matter Connections and Memory: the STRATEGIC Study (STRATEGIC)

Stroke | Cognitive Impairment | Memory Impairment
Dart NeuroScience, LLC

Completed

HT-0712 vs. Placebo in Subjects With Age-Associated Memory Impairment (AAMI) (PRIME)

Age-Associated Memory Impairment (AAMI)

United States
Ludwig-Maximilians - University of Munich

Completed

Outcome Predictors of a Cognitive Intervention in aMCI (OutPreC MCI)

Amnestic Mild Cognitive Impairment

Germany
CHU de Reims

Recruiting

Better Understanding Slow Language Impairment (SLI:COGGEN)

Slow Language Impairment

France
Nantes University Hospital

Terminated

Study of Visual-spatial Attention by Eye Tracking as a Function of Central or Peripheral Visual Impairment (BEHAVE)

Central or Peripheral Visual Impairment

France
Instituto de Medicina Molecular João Lobo Antunes
Fundação para a Ciência e a Tecnologia

Completed

Impact of Physical Activity in Vascular Cognitive Impairment ( AFIVASC ) (AFIVASC)

Vascular Cognitive Impairment

Portugal
Johns Hopkins University
National Institute on Aging (NIA)

Completed

Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI)

Mild Cognitive Impairment (MCI)

United States
University Medicine Greifswald
University of Greifswald

Recruiting

Cognitive Training and Brain Stimulation in Women With Post-chemotherapy Cognitive Impairment (NeuroMod-PCCI)

Breast Cancer | Cognitive Impairment

Germany
University of North Carolina, Chapel Hill
Med-El Corporation

Active, not recruiting

Outcomes in Children With Pre-operative Residual Hearing

High Frequency Sensorineural Hearing Impairment | Hearing Disorders in Children

United States
Fudan University

Unknown

Effects of Docosahexanoic Acid on Neurocognitive Impairment in HIV-infected Patients

Neurocognitive Impairment

China
Providence VA Medical Center
US Department of Veterans Affairs

Unknown

Disseminating a Dashboard for VA Purchased Community Nursing Homes (CNHDashboard)

Veterans | Nursing Home | Quality of Care | Functional Impairment
University of Texas Southwestern Medical Center
TEXAS ALZHEIMER'S RESEARCH & CARE CONSORTIUM

Recruiting

Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment (COBALT)

Dementia | Mild Cognitive Impairment | Amnestic Mild Cognitive Impairment - aMCI

United States
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
University of Aberdeen
NHS Grampian

Recruiting

Chemotherapy Induced Cognitive Impairment (CONCERT)

Breast Cancer

United Kingdom
Creighton University
National Institutes of Health (NIH)

Recruiting

Improving Physical Activity With Cognitive Impairment

Mild Cognitive Impairment | Caregiver Burnout

United States
Taipei Medical University
National Health Research Institutes, Taiwan

Recruiting

Temporal Relations and Exercise Interventions of Various Gait and Cognitive Domains in Older Adults

Mild Cognitive Impairment | Fallers

Taiwan
Novartis Pharmaceuticals

Completed

An Open-label, Parallel-group Study to Determine the Pharmacokinetics of a Single Dose of AFQ056 in Subjects With Renal Impairment Compared to Healthy Subjects

Mild Moderate | or Severe Renal Impairment

Germany
Newron Pharmaceuticals SPA

Completed

A Trial to Explore the Potential Benefit of Safinamide on Cognitive Impairment Associated With Parkinson's Disease

Parkinson's Disease With Cognitive Impairments

Spain, United States
AstraZeneca

Recruiting

A Phase I Study to Investigate the Effect of Hepatic Impairment on the PK, Safety, and Tolerability of AZD2693

Hepatic Impairment

United States
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

Study to Evaluate Orelabrutinib Tablets in Subjects With Hepatic Impairment and Healthy Subject

Hepatic Impairment

China
CTI BioPharma
PPD

Recruiting

Study to Evaluate the Safety, Tolerability, and PK of Pacritinib

Hepatic Impairment

United States
Chipscreen Biosciences, Ltd.

Recruiting

Pharmacokinetics of Chiglitazar in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Impairment

China
Eisai Co., Ltd.

Recruiting

Study to Evaluate the Pharmacokinetics (PK) of E7090 (Herein Referred to as Tasurgratinib) and Its Metabolite in Participants With Mild and Moderate Hepatic Impairment Compared to Healthy Participants

Hepatic Impairment

Japan
SK Life Science, Inc.

Completed

Safety Study of Cenobamate in Subjects With Normal Hepatic Function and Subjects With Severe Hepatic Impairment

Hepatic Impairment

Poland, Slovakia
Novartis Pharmaceuticals
Pharmaceutical Research Associates

Withdrawn

Pharmacokinetics of TNO155 in Participants With Mild, Moderate, or Severe Hepatic Impairment Compared to Matched Healthy Participants

Hepatic Impairment
Novartis Pharmaceuticals

Completed

A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants

Hepatic Impairment

Hungary
Institut de Recherches Internationales Servier

Completed

A Study of Vorasidenib in Participants With Moderate or Mild Hepatic Impairment and Matched Participants With Normal Hepatic Function

Hepatic Impairment

United States
Reata, a wholly owned subsidiary of Biogen

Completed

A Pharmacokinetic Study of Omaveloxolone in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Impairment

United States
Pfizer

Completed

Single-Dose PK and Safety Study of GBT440 in Subjects With Hepatic Impairment

Hepatic Impairment

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study to Evaluate the Pharmacokinetics and Safety of DBPR108 in Subjects With Hepatic Impairment

Hepatic Impairment

China
Concert Pharmaceuticals

Completed

Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of CTP-543

Hepatic Impairment

United States
Janssen Research & Development, LLC

Terminated

A Study of JNJ-53718678 in Participants With Hepatic Impairment

Hepatic Impairment

United States
Novartis Pharmaceuticals

Completed

Pharmacokinetics of BAF312 in Patients With Hepatic Impairment

Hepatic Impairment

Hungary, Russian Federation
Sichuan Haisco Pharmaceutical Group Co., Ltd
The First Hospital of Jilin University

Completed

Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Hepatic Impairment

Hepatic Impairment

China

Clinical Trials on Impairment

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