Clinical Trials on Incompetence, Functional

Total 3735 results

Zhenhua Zen

Completed

Acute Kidney Injury in Patients Hospitalized With COVID-19

COVID-19 | Acute Kidney Injury | Kidney Function

China
Brigham and Women's Hospital
Boston Scientific Corporation; American Society for Gastrointestinal Endoscopy

Recruiting

A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG)

Obesity | Non-alcoholic Fatty Liver Disease (NAFLD) | Liver Function | Non-alcoholic Steatohepatitis (NASH) | Liver Fibroses | Endoscopic Ultrasound | Endoscopic Sleeve Gastroplasty

United States
Regeneron Pharmaceuticals

Available

Expanded Access to REGN4461 for Patients With Lipodystrophy or Monogenic Obesity With Complications of Leptin Deficiency or Deficient Leptin Signaling

Partial Lipodystrophy | Generalized Lipodystrophy | Monogenic Obesity Due to LEP or LEPR Loss of Function
Mansoura University

Active, not recruiting

Effect of Concomitant Bladder Neck Incision and Urethral Valve Ablation on Surgical Re-intervention Rate for Patients With Posterior Urethral Valve

Renal Function Disorder | Pediatric Disorder | Hydronephrosis, Secondary | Hydronephrosis in Children | Hydronephrosis Congenital | Bladder-Neck; Obstruction, Congenital | Urethral Valve

Egypt
Charite University, Berlin, Germany

Withdrawn

Perioperative Assessment of Right Ventricular Function and Venous Return in Patients With Epithelial Ovarian Cancer Undergoing Cytoreductive Surgery (Gyn Right) - Pilot Study

Right Ventricular Function and Venous Return

Germany
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Comparative Evaluation of Efficacy and Safety of Toremifene, Tamoxifen, and Aromatase Inhibitor Plus Ovarian Function Suppression in Hormone Receptor-Positive Early Breast Cancer Among Non-Low-Risk Premenopausal Women: A Real-World Study

Premenopausal Breast Cancer | Hormone-receptor-positive Breast Cancer | Breast Cancer Patients at Intermediate to High Risk | Ovarian Function Suppression Combined With Aromatase Inhibitor or Tamoxifen or Torimefen

China
Linkoeping University

Recruiting

Physiological Studies in Post-COVID-19 Syndrome, and the Association With DNA Methylation

Covid19 | Dyspnea | Lung Function Decreased | Cardiopulmonary Disease | Epigenetic Disorder

Sweden
Peking Union Medical College Hospital

Completed

Initial Volume Status in Patients With Acute Brain Injury is Associated With Neurological Prognosis

Acute Brain Injury | Paroxysmal Sympathetic Hyperactivity | Volume Status | Right Heart Function | Right Cardiogenic Pulmonary Edema | Glasgow Outcome Scale Extended

China
University Hospital of North Norway
Helse Nord

Withdrawn

Effects of Structured Rehabilitation Program on Quality of Life in Rectal Cancer Patients- a Randomized Controlled Trial

Quality of Life | Urinary Incontinence | Anal Incontinence | Sexual Function

Norway
Celgene

Completed

Study of Pomalidomide to Evaluate the Pharmacokinetics and Safety for Patients With Multiple Myeloma and Impaired Renal Function (POM Renal) (POM Renal)

Multiple Myeloma | Renal Impairment

United States, Canada
Second Affiliated Hospital, School of Medicine,...

Completed

Clinical Characteristics, Treatment and Prognosis of Chest Tightness Variant Asthma

Quality of Life | Asthma | Eosinophilia | Nitric Oxide | Airway Responsiveness | Clinical Depression | Chest Syndrome | Lung Function | Clinical Anxiety | Induced Sputum

China
Zhebao Wu
The First Affiliated Hospital of Nanchang University; Shanghai Zhongshan Hospital and other collaborators

Unknown

The Impact of Endoscopic Pituitary Surgery on Nasal Function

Quality of Life | Pituitary Tumor | Endoscopic Surgery | Function of Nose

China
Instituto de Seguridad y Servicios Sociales de...

Completed

School-Based Program On Metabolic Disease

Liver Diseases | Kidney Diseases | Obesity | Diabetes Mellitus, Type 2 | Physical Fitness | Cardiovascular Function

Mexico
Johns Hopkins University
National Institute on Aging (NIA)

Active, not recruiting

Sight and Hearing Investigation Into Effects on Delirium (SHIELD)

Delirium | Delirium on Emergence | Hearing Loss | Hearing Loss, High-Frequency | Hearing Loss, Sensorineural | Delirium, Cause Unknown | Hearing Loss, Bilateral | Hearing Disability | Delirium in Old Age | Delirium of Mixed Origin | Delirium Superimposed on Dementia | Delirium Confusional State | Delirium With... and other conditions

United States
Boston Children's Hospital

Completed

Offset Analgesia as a Measure of Central Sensitization in Children

CRPS (Complex Regional Pain Syndromes) | Chronic Pain Syndrome | Musculoskeletal Pain Disorder | Chronic Daily Headache | Functional Abdominal Pain Syndrome

United States
Children's Cancer and Leukaemia Group

Active, not recruiting

Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy

Brain and Central Nervous System Tumors | Ototoxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Novartis

Completed

Ribociclib in Treating Patients With Advanced Neuroendocrine Tumors of Foregut Origin

Intermediate Grade Lung Neuroendocrine Neoplasm | Low Grade Lung Neuroendocrine Neoplasm | Functional Pancreatic Neuroendocrine Tumor | Advanced Digestive System Neuroendocrine Neoplasm | Duodenal Neuroendocrine Tumor G1 | Gastric Neuroendocrine Tumor | Nonfunctional Pancreatic Neuroendocrine... and other conditions

United States
Summa Health System

Completed

Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain

Irritable Bowel Syndrome | Fibromyalgia | Post Traumatic Stress Disorder | Interstitial Cystitis | Chronic Pelvic Pain

United States
Sichuan Academy of Medical Sciences

Recruiting

Exercise Improves Gastrointestinal Function in Peritoneal Dialysis Patients

Quality of Life | Chronic Kidney Diseases | Peritoneal Dialysis | Exercise | Gastrointestinal Function

China
University Health Network, Toronto

Not yet recruiting

meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis (CANARY)

End Stage Kidney Disease | Kidney Dysfunction | Peritoneal Dialysis Complication | Sodium-glucose Co-transporter-2 Inhibitors | Residual Kidney Function

Canada
Cancer Institute and Hospital, Chinese Academy...

Completed

HA-WBRT-SIB for Brain Metastasis of Lung Cancer

Cognitive Function | Brain Metastases | Lung Neoplasm | Simultaneous Integrated Boost | Hippocampal Avoidance

China
Centro Hospitalar Universitario do Algarve
Universidade do Algarve

Active, not recruiting

Assessment of Long-term Sequelae of Coronavirus Disease 2019 (COVID-19) Pneumonia With Chest CT and Pulmonary Function Tests

COVID-19 Pneumonia | SARS CoV 2 Infection | Sequelae of; Infection | Respiratory Function Impaired | SARS-CoV 2 Pneumonia

Portugal
Johns Hopkins Bloomberg School of Public Health
Odense University Hospital; Karolinska Institutet; Charite University, Berlin... and other collaborators

Completed

Dietary Intake in Adults From the GA2LEN Folow-up Survey

Asthma | Allergic Rhinitis | COPD | Food Allergy | Lung Function Decreased | Atopy | Allergic Sensitisation

United States
Radboud University Medical Center
Dutch Cancer Society

Completed

The Vascular and Metabolic Effects of Sunitinib in Patients With Metastatic Renal Cell Carcinoma

Renal Cell Carcinoma | Hypertension | Insulin Sensitivity | Renal Function

Netherlands
Medical College of Wisconsin
University College, London; Indiana University

Recruiting

Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome

Functional Gastrointestinal Disorders | Postural Orthostatic Tachycardia Syndrome | Hypermobile Ehlers-Danlos Syndrome | Autonomic Nervous System Disease | Autonomic Nervous System Imbalance

United States
University of New Mexico
University of Texas at Austin; Albany Medical College

Terminated

Pelvic Floor Disorders Among Sexual Minoritized Women (PRIDE)

Urinary Incontinence | Pelvic Organ Prolapse | Fecal Incontinence | Sexual Function Disturbances

United States
Cedars-Sinai Medical Center

Completed

C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI (C1INHDGF)

End Stage Renal Disease | Ischemic Reperfusion Injury | Kidney Failure | Delayed Graft Function

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Study of Symptoms Caused by Cancer and Cancer Therapy in Patients With Invasive Breast, Lung, Prostate, or Colorectal Cancer

Pain | Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
Johns Hopkins University
National Institute on Deafness and Other Communication Disorders (NIDCD); Labyrinth...

Active, not recruiting

Multichannel Vestibular Implant Early Feasibility Study

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity

United States
Progenity, Inc.

Completed

Collection of Samples From Pregnant Women for the Evaluation of Preeclampsia (Pre-E) Biomarkers

Hypertension | Renal Insufficiency | Proteinuria | Thrombocytopenia | Preeclampsia | Pulmonary Edema | Impaired Liver Function

United States
University of Stavanger
Stavanger Municipality, Norway

Recruiting

Health Determinants in Older Adults Living at Home

Frailty | Healthy Aging | Alcohol Use, Unspecified | Mental Health Issue | Social Functioning | Vision and Hearing Loss | Cognitive Function, Social 1

Norway
Johns Hopkins University
National Institute on Aging (NIA); Labyrinth Devices, LLC

Recruiting

Vestibular Implantation in Older Adults

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Bilateral Vestibulopathy | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity | Bilateral Vestibular Hypofunction | Aminoglycoside Ototoxicity | Presbyvestibulopathy

United States
Johns Hopkins University
National Institute on Deafness and Other Communication Disorders (NIDCD); Labyrinth...

Recruiting

Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular Hypofunction

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Bilateral Vestibulopathy | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity | Bilateral Vestibular Hypofunction | Aminoglycoside Ototoxicity

United States
Xuanwu Hospital, Beijing

Recruiting

Spinal Cord Stimulation Therapy for Hereditary Spastic Paraplegias Patients

Gait | Motor Function

China
University of Southern California
Kaiser Permanente

Completed

Genetics of Beta Cell Failure in Mexican Americans

Obesity | Physical Activity | Insulin Resistance | Genetics | Air Pollution | Gestational Diabetes | Nutrition | Diabetes Type 2 | Adipokines | Beta Cell Function
Dr Anders Ullén

Completed

A Trial With Vinflunine in Patients With Metastatic Bladder Cancer and Impaired Renal Function (VINGEM)

Bladder Cancer | Urothelial Carcinoma | Urethra Cancer | Ureter Cancer | Renal Pelvis Cancer

Denmark, Sweden
Vanderbilt University Medical Center

Recruiting

Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals (RARE-PAH)

Idiopathic Pulmonary Arterial Hypertension | Heritable Pulmonary Arterial Hypertension | Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo | Healthy Individuals With no Cardiopulmonary Disease

United States
Gilead Sciences

Recruiting

A Multiple-Dose Study of Bulevirtide in Participants With Normal and Impaired Renal Function

Chronic Hepatitis D Infection

United States
Instituto de Ciências Biomédicas Abel Salazar

Completed

Evaluation of the Functional Impact of Adenotonsilectomy

Infections | Tonsillitis | Apnea, Obstructive | Tonsillar Hypertrophy | Respiratory Function Impaired | ENT Disorder

Portugal
University Hospital, Caen
LivaNova

Completed

Sleep Apnea Diagnosis Using a Novel Pacemaker Algorithm and Link With Aldosterone Plasma Level in Patients Presenting With Diastolic Dysfunction (SAPAAD)

Arrhythmias, Cardiac | Sleep Apnea | Hyperaldosteronism | Cardiac Diastolic Function

France
APOGEPHA Arzneimittel GmbH

Completed

Efficacy and Tolerability of Propiverine Hydrochloride in Patients With Neurogenic Detrusor Overactivity

Urologic Diseases | Urinary Incontinence | Urinary Bladder, Neurogenic | Neurogenic Urinary Bladder Disorder | Bladder Disorder, Neurogenic | Urinary Bladder Disorder, Neurogenic | Neurogenic Bladder Disorder | Urinary Bladder Neurogenic Dysfunction | Overactive Detrusor Function

Romania, Austria, Germany
Lumbini Medical College

Completed

Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation

Chronic Rhinosinusitis (Diagnosis) | Nasal Polyps | Deviated Nasal Septum | Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia

Nepal
University Hospital Muenster

Unknown

Mucoid Staphylococcus Aureus in Cystic Fibrosis Airways (mucostaph)

Lung Diseases | Cystic Fibrosis | Lung Function Decreased | Staphylococcus Aureus Pneumonia

Germany, Austria
Wageningen University

Active, not recruiting

Prospective Cohort Study of 4,837 Post-myocardial Infarction Patients (Alpha Omega Cohort)

Cardiovascular Diseases | Mortality | Type 2 Diabetes Mellitus | Cognitive Decline | Mental Well-being | Kidney Function

Netherlands
University of Alabama at Birmingham
National Institutes of Health (NIH); Mereo BioPharma

Completed

Alvelestat (MPH966) for the Treatment of ALpha-1 ANTitrypsin Deficiency (ATALANTa)

Emphysema or COPD | Alpha-1 Antitrypsin Deficiency (AATD) | Pi*ZZ, Pi*SZ, Pi*Null, Another Rare Phenotype/Genotype Known to be Associated With Either Low or Functionally Impaired AAT Including F or I Mutations

United States
University of Pittsburgh

Suspended

Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study (GREAT1)

Multiple Sclerosis | Diabetes Mellitus | Chronic Kidney Diseases | Gastritis | Rheumatoid Arthritis | Chronic Pain | Irritable Bowel Syndrome | Hepatitis | Inflammatory Bowel Diseases | Dyslipidemias | Chronic Disease | Celiac Disease | Cholecystitis | Crohn Disease | Cystic Fibrosis | Chronic Pancreatitis | NASH - Nonalcoholic... and other conditions

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Registry of Older Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Cognitive/Functional Effects | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Celgene

Completed

Pharmacokinetics and Safety Study of Azacitidine in Cancer Patients With and Without Impaired Renal Function (RENAL)

Multiple Myeloma | Non-Hodgkin's Lymphoma | AML | Solid Tumors | MDS | Hodgkin's Disease

United States
National Defense Medical Center, Taiwan

Completed

Effects of Biofeedback in Patients With Acute Cerebral Infarction

Psychological Distress | Acute Ischemic Stroke | Biofeedback | Autonomic Dysfunction, Cognitive Function
The University of Texas Health Science Center at...

Completed

Metabolism of Low Carbohydrate and Ketogenic Diet

Diabetic Kidney Disease | Weight Loss | Cognitive Function | Type2 Diabetes | Diabetic Control

United States

Clinical Trials on Incompetence, Functional

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Medical Conditions

Drug Interventions

CROs by country

CROs in Vietnam

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Rare Diseases

Drug Interventions

Dietary Supplements

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