Clinical Trials on Infection, Laboratory in Czechia

Total 587 results

Pfizer

Completed

Clostridium Difficile Vaccine Efficacy Trial (Clover)

Clostridium Difficile Infection

United States, Spain, Belgium, Taiwan, Japan, Portugal, Colombia, Korea, Republic of, Poland, Australia, Germany, Canada, Argentina, Bulgaria, Chile, Czechia, Finland, France, Hungary, Peru, Slovakia, Sweden, United Kingdom
Spero Therapeutics

Completed

Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (ADAPT-PO)

Acute Pyelonephritis | Complicated Urinary Tract Infection

Bulgaria, Georgia, United States, Czechia, Estonia, Hungary, Latvia, Moldova, Republic of, Poland, Romania, Russian Federation, Serbia, Slovakia, South Africa, Ukraine
Melinta Therapeutics, Inc.
Department of Health and Human Services

Completed

Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP

Acute Pyelonephritis | Urinary Tract Infection Complicated

Italy, Spain, Greece, Peru, United States, Bulgaria, Slovenia, Hungary, Romania, Brazil, Slovakia, Czechia, Ukraine, Taiwan, Belarus, Poland, Korea, Republic of
Merck Sharp & Dohme LLC

Active, not recruiting

Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007)

RSV Infection

United States, Australia, Canada, Chile, Colombia, Czechia, Finland, France, Germany, Greece, Hong Kong, Hungary, Italy, Japan, Malaysia, Mexico, New Zealand, Norway, Peru, Puerto Rico, Singapore, South Africa, Spain, Taiwan, Thailand, Tu... and more
Pfizer
Biomedical Advanced Research and Development Authority; Innovative Medicines...

Completed

A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria. (REVISIT)

Ventilator Associated Pneumonia | Complicated Intra-abdominal Infection | Hosptial Acquired Pneumonia

Spain, China, Korea, Republic of, Philippines, United States, Romania, Taiwan, Italy, Malaysia, Mexico, India, Israel, Turkey, Greece, Thailand, Czechia, Croatia, Argentina, Russian Federation, Bulgaria, Ukraine
Pfizer
Forest Laboratories

Completed

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)

Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis

Croatia, Bulgaria, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, Spain, Romania, Ukraine, United States, Argentina, Czechia, Israel, Taiwan, Germany, Italy
Galapagos NV

Completed

A Study to Assess Efficacy and Safety of Filgotinib in Ankylosing Spondylitis (TORTUGA)

Ankylosing Spondylitis

Belgium, Bulgaria, Czechia, Estonia, Poland, Spain, Ukraine
Charles University, Czech Republic
Eli Lilly and Company

Completed

Abciximab in Patients Undergoing Percutaneous Coronary Intervention for Cardiogenic Shock

Shock, Cardiogenic

Czech Republic
Bambino Gesù Hospital and Research Institute
Radboud University Medical Center; University of Exeter; Consorzio per Valutazioni...

Recruiting

A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection (cASPerCF)

Cystic Fibrosis | Aspergillosis

Ireland, Spain, Netherlands, France, United Kingdom, Czechia, Germany, Greece, Italy, Portugal, Switzerland
B. Braun Melsungen AG

Terminated

Gelatin in ICU and Sepsis (GENIUS)

Hypovolemia

Spain, Austria, Germany, Czechia, France
University Hospital Ostrava

Completed

REsistance to Aspirin and Clopidogrel in acuTe Myocardial Infarction (REACT-MI)

Acute Myocardial Infarction

Czech Republic
GlaxoSmithKline

Completed

Comparison of Adjuvanted Hepatitis B Vaccine to Double Dose of Engerix™-B in Pre- /Haemodialysis Patients Aged ≥15 Years

Hepatitis B

Spain, Czech Republic, Malaysia
Masaryk University

Recruiting

COVID-19 Vaccines Safety Tracking (CoVaST)

Adverse Reaction to Vaccine | COVID19 Vaccine

Poland, Canada, United States, Croatia, Czechia, Estonia, Ethiopia, Germany, Ghana, Mexico, Portugal, Russian Federation, Serbia, Slovenia
The Faculty Hospital Na Bulovce

Completed

Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures

Small Bowel Obstruction | Acute Appendicitis | Perforated Gastroduodenal Ulcer

Czech Republic
Gilead Sciences

Completed

A Study of Response-Guided Duration of Combination Therapy With GS-9190, GS-9256, Pegasys® and Copegus® in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C

Chronic Hepatitis C Infection

United States, Spain, United Kingdom, Canada, Germany, France, Austria, Poland, Belgium, Czech Republic, Italy
European Clinical Research Alliance for Infectious...
Centre Hospitalier Universitaire Dupuytren de Limoges (CHUL); Université de... and other collaborators

Recruiting

Perpetual Observational Study - Ventilator Associated Pneumonia (POS-VAP)

Ventilator Associated Pneumonia

Spain, Belgium, Serbia, Netherlands, Czechia, Germany, Greece, Albania, Romania, Croatia, France, Italy, United Kingdom
St George Street Capital

Completed

AZD1656 in Diabetic Patients Hospitalised With Suspected or Confirmed COVID-19 (ARCADIA)

Covid19

Czechia, Romania, United Kingdom
GlaxoSmithKline

Completed

Evaluate Vaccine Against Chickenpox and a Combined Vaccine Against 4 Viral Childhood Diseases: Measles, Mumps, Rubella and Chickenpox

Varicella | Chickenpox Vaccines

Russian Federation, Romania, Czechia, Slovakia, Italy, Sweden, Poland, Greece, Norway, Lithuania
Brno University Hospital

Unknown

Utility of Presepsin in Children Sepsis

Sepsis Syndrome

Czech Republic
Rostrum Medical Innovations Inc.
Medical Initiatives

Not yet recruiting

Evaluation of VQm PHM on Pulmonary Health Parameters for ICU

Stroke | Pneumonia | COPD | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Ventilators, Mechanical

France, United States, Austria, Czechia
GlaxoSmithKline

Completed

Safety & Immunogenicity of Pneumococcal Vaccine 2189242A Co-administered With DTPa-HBV-IPV/Hib in Healthy Infants

Infections, Streptococcal

Germany, Czechia, Sweden, Poland
Biota Pharmaceuticals, Inc.

Completed

A Phase 2 Study of Vapendavir in Asthmatic Adults With Symptomatic Human Rhinovirus Infection (SPIRITUS)

Asthma

United States, Bulgaria, Czechia, Georgia, Poland, Romania
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Recruiting

Advantageous Predictors of Acute Coronary Syndromes Evaluation (APACE) Study (APACE)

Myocardial Infarction | Angina, Unstable

Spain, Switzerland, Czechia, Italy, Poland
Novartis Pharmaceuticals

Recruiting

Study of Efficacy and Safety of Investigational Treatments in Patients With Moderate to Severe Hidradenitis Suppurativa

Hidradenitis Suppurativa

Spain, France, United States, Austria, Germany, Hungary, Belgium, Iceland, Netherlands, Denmark, Czechia
Janssen Infectious Diseases BVBA

Completed

A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment

Hepatic Impairment

Germany, Czech Republic
University of Minnesota
National Health and Medical Research Council, Australia; Bristol-Myers Squibb; National Institutes of Health Clinical Center (CC) and other collaborators

Completed

Strategic Timing of Antiretroviral Treatment (START)

HIV Infection

Spain, United States, United Kingdom, Ireland, Australia, Argentina, Denmark, Sweden, Israel, Switzerland, Germany, Brazil, Norway, Chile, Thailand, Peru, Portugal, Greece, Luxembourg, Uganda, Austria, Belgium, Czechia, Estonia, Finland, ... and more
MedImmune LLC
National Institute of Allergy and Infectious Diseases (NIAID); Antibacterial... and other collaborators

Completed

Effort to Prevent Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa in Mechanically Ventilated Subjects (EVADE)

Pseudomonas Aeruginosa

Spain, United States, Belgium, France, Hungary, United Kingdom, Israel, Austria, Portugal, Greece, Czechia, Turkey, Croatia, Ireland
GlaxoSmithKline

Completed

Prophylactic Antipyretic Treatment in Children Receiving Pneumococcal Conjugate and Standard Infant Vaccines

Infections, Rotavirus

Czech Republic
Charles University, Czech Republic
University Hospital Pilsen; University Hospital Hradec Kralove; Na Homolce Hospital and other collaborators

Completed

Trial Comparing Radial and Femoral Approach in Primary Percutaneous Coronary Intervention (PCI) (STEMI-RADIAL)

ST Elevation Myocardial Infarction

Czech Republic
Novartis
Ministry of Health, Czech Republic

Completed

Fluvastatin in the Therapy of Acute Coronary Syndrome

Myocardial Infarction | Coronary Disease

Czech Republic
University Hospital Ostrava
Palacky University

Completed

SONOlysis in Prevention of Brain Infarctions dUring Carotid Stenting and caroTid EndaRterectomy (SONOBUSTER)

Internal Carotid Artery Stenosis

Czech Republic
Pfizer
Forest Laboratories

Completed

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)

Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis

Croatia, Brazil, Bulgaria, Korea, Republic of, Russian Federation, Hungary, Poland, Romania, Ukraine, Argentina, Israel, Portugal, Greece, Taiwan, Japan, Slovakia, Serbia, United States, Mexico, Germany, Turkey, Czechia
Janssen Research & Development, LLC

Active, not recruiting

An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B Participants (OCTOPUS-1)

Hepatitis B, Chronic

France, Canada, Czechia, Italy, Taiwan, Turkey, Spain, United Kingdom
Eli Lilly and Company

Completed

A Study of Ixekizumab (LY2439821) in bDMARD-Naive Participants With Radiographic Axial Spondyloarthritis (COAST-V)

Spondyloarthritis

Taiwan, United States, Korea, Republic of, Germany, Czechia, Japan, Netherlands
Oslo University Hospital
Institut National de la Santé Et de la Recherche Médicale, France; Epidemiological...

Terminated

EU SolidAct: An Adaptive Pandemic and Emerging Infection Platform Trial (Bari-SolidAct)

COVID-19 | Emerging Infectious Disease

Spain, Belgium, France, Norway, Ireland, Luxembourg, Greece, Slovakia, Hungary, Portugal, Austria, Czechia, Germany, Italy, Turkey
Arsanis, Inc.

Terminated

Prevention of S. Aureus Pneumonia Study in Mechanically Ventilated Subjects Who Are Heavily Colonized With S. Aureus.

Pneumonia, Ventilator-associated | Pneumonia, Staphylococcal

United States, Spain, France, Czechia, Portugal, Israel, Romania, Russian Federation, Hungary, Poland, Ukraine, India, Austria, Georgia, Serbia, South Africa
Pfizer

Terminated

A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children

Invasive Aspergillosis

Spain, United States, Singapore, Canada, Czechia, Netherlands, Poland, Thailand
Żelazna Medical Centre, LLC
Charles University, Czech Republic; Karolinska Institutet; Charite University... and other collaborators

Unknown

Risk Factors for Anxiety and Depression Among Pregnant Women During the COVID-19 Pandemic (MindCOVID)

Depression | Anxiety | Pregnancy Related

Lebanon, Hong Kong, United States, Sweden, Germany, Australia, Poland, Italy, Taiwan, Albania, Czechia, France, Israel, Norway, Spain
GlaxoSmithKline

Completed

Safety and Immunogenicity of 3 Lots of GSK Biologicals' HBV-MPL Vaccine and Engerix™-B in Healthy Volunteers ≥ 15y

Hepatitis B

Australia, Czech Republic, Germany, Italy, Netherlands, Switzerland, United Kingdom
Sanofi

Active, not recruiting

A Study to Test the Efficacy and Safety of SAR442970 in Adults With Hidradenitis Suppurativa (HS OBTAIN)

Hidradenitis Suppurativa

Czechia, Belgium, Netherlands, Chile, Australia, Germany, Italy, United States, Canada, Denmark, France, Greece, Poland, Spain, Sweden
Hoffmann-La Roche

Completed

A Study of Combination Treatment With Peginterferon Alfa-2a (Pegasys) Plus Ribavirin (Copegus) in Participants With Chronic Hepatitis C

Hepatitis C, Chronic

Czechia, Slovakia
GlaxoSmithKline

Completed

A Study to Assess Frailty of Subjects During ZOSTER-006 and ZOSTER-022

Herpes Zoster

United States, Australia, Germany, Spain, Japan, Taiwan, Sweden, Korea, Republic of, Hong Kong, Mexico, Canada, France, Italy, Brazil, Estonia, United Kingdom, Czechia, Finland
Abbott Biologicals
Quintiles, Inc.

Completed

Immunogenicity and Safety of a Cell-derived Influenza Vaccine in Elderly

Influenza Vaccines

Czech Republic, Estonia, Lithuania
Universitaire Ziekenhuizen KU Leuven

Terminated

Supplemental Corticosteroids in Cirrhotic Hypotensive Patients With Suspicion of Sepsis (SCOTCH;)

Liver Cirrhosis

Spain, United Kingdom, Denmark, Germany, Czechia, Belgium, Italy
Novartis Vaccines

Completed

One Year Antibody Persistence After a Fourth Dose Boost or Two Catch-Up Doses of Novartis Meningococcal B Recombinant Vaccine Administered Starting From 12 Months of Age and Response to a Third Dose Boost or Two Catch-Up Doses Starting at 24 Months of Age

Meningococcal Disease

Finland, Czech Republic
Novartis Pharmaceuticals

Completed

16-week Efficacy and 3-year Safety, Tolerability and Efficacy of Secukinumab in Active Ankylosing Spondylitis Patients (MEASURE 3)

Spondylitis, Ankylosing

Germany, Spain, United Kingdom, United States, Belgium, Greece, Portugal, Russian Federation, Czechia, Mexico
AbbVie

Completed

Effectiveness of Adalimumab in Moderate to Severe HidrAdenitis SuppuRativa Patients - a Multi cOuNtry studY in Real Life Setting (HARMONY)

Hidradenitis Suppurativa

Austria, Belgium, Czechia, Germany, Greece, Hungary, Ireland, Israel, Lebanon, Slovenia, Switzerland, Turkey, United Kingdom
AstraZeneca

Completed

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended Lower Respiratory Tract Infection Due to Respiratory Syncytial Virus in Healthy Late Preterm and Term Infants (MELODY) (MELODY)

Respiratory Syncytial Virus Infections

United States, Finland, Spain, Belgium, France, Korea, Republic of, Turkey, Austria, New Zealand, South Africa, Australia, Germany, Bulgaria, United Kingdom, Ukraine, Argentina, Czechia, Panama, Estonia, Lithuania, Poland, Japan, Co... and more
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine When Co-administered With Routine Pediatric Vaccines in Healthy Infants and Toddlers in Europe

Meningococcal Infections

Czechia, Finland, Italy, Poland, Romania, Spain, Sweden
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of Infanrix Hexa in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery

Tetanus | Diphtheria | Acellular Pertussis | Poliomyelitis | Diphtheria-Tetanus-aPertussis-Hepatitis B-Poliomyelitis-Haemophilus Influenzae Type b Vaccines

Finland, Australia, Spain, Italy, Canada, Czechia

Clinical Trials on Infection, Laboratory in Czechia

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