Clinical Trials on Infections, Streptococcal in South Africa

Total 3293 results

University of Miami
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Implementing a Comprehensive Prevention of Mother-to-Child Transmission of HIV Program for South African Couples

Pregnancy | HIV

South Africa
University of Cape Town
Imperial College London; Institute of Tropical Medicine, Belgium; European and... and other collaborators

Completed

Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of Prednisone (Pred-ART)

HIV | Tuberculosis | Immune Reconstitution Inflammatory Syndrome

South Africa
University of Stellenbosch
London School of Hygiene and Tropical Medicine; Makerere University; Leiden University... and other collaborators

Recruiting

Point-of-care Triage Test for Active Tuberculosis (TriageTB)

Tuberculosis | Tuberculosis, Pulmonary

South Africa
Foundation for Professional Development (Pty) Ltd
National Institutes of Health (NIH); University of California, Irvine; National... and other collaborators

Completed

Acceptability and Feasibility of Home-based TB Testing

Tuberculosis, Pulmonary | Households

South Africa
Global Alliance for TB Drug Development

Completed

A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001)

Pulmonary Tuberculosis

South Africa
Tuberculosis Clinical Diagnostics Research Consortium
University of Cape Town

Unknown

Feasibility of a Lateral Flow Urine LAM Test for Diagnosis of Tuberculosis in South Africa

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Miliary

South Africa
Sanofi Pasteur, a Sanofi Company

Completed

Study to Evaluate the Immune Response After Booster Vaccination With Tdap-IPV Vaccine (Against Tetanus, Diphtheria, Pertussis and Poliomyelitis) in Children Who Received Different Pertussis Primary Vaccine Regimens in Republic of South Africa

Pertussis Immunisation | Diphtheria Immunisation | Tetanus Immunisation | Poliomyelitis Vaccine

South Africa
Boston Medical Center
Boston University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Completed

The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes

Tuberculosis | Alcohol Consumption | Treatment Adverse Effect

South Africa
TASK Applied Science

Completed

Study to Evaluate EBA, Safety and Tolerability of Carbapenems in Adults With Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
GlaxoSmithKline

Completed

Study to Asses DTPw-HBV/Hib at 15-18 Months (m) and Mencevax™ ACW at 24 to 30 m in Primed Subjects

Infections, Meningococcal

South Africa
University of Stellenbosch

Recruiting

Evaluation of New Biomarker-based Approaches for Improving the Diagnosis of Childhood Tuberculous Meningitis (TBMBIOMARKER)

Tuberculous Meningitis

South Africa
McGill University Health Centre/Research Institute...
University of Cape Town Lung Institute

Recruiting

A Randomized Controlled Trial of a Digital, Self-testing Strategy for COVID-19 Infection in South Africa.

COVID-19

South Africa
Foundation for Innovative New Diagnostics, Switzerland

Completed

Evaluation of the Performance of Rapid Diagnostics for SARS-CoV-2 Self-testing in the Hands of Untrained (CV009)

COVID-19

South Africa, Uganda
University of Massachusetts, Worcester
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Recruiting

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)

Tuberculosis | Pulmonary Tuberculosis | HIV Coinfection

South Africa
GlaxoSmithKline

Completed

Assess the Immune Response Following Primary Vaccination With GSK Biologicals' Tritanrix™-HepB/Hib-MenAC vs Tritanrix™-HepB/Hiberix™ Given at 6,10 & 14 Wks of Age to Infants Who Received Hepatitis B Vaccine at Birth

Diphtheria; Haemophilus Influenzae Type b; Hepatitis B; Tetanus; Whole Cell Pertussis

South Africa
Pfizer

Completed

Post Market Surveillance to Observe Safety of Prevenar13™ in Adults

Pneumococcal Disease

Korea, Republic of
TASK Applied Science

Recruiting

A Phase 2 Trial to Evaluate the EBA, Safety and Tolerability of Eto Alone and in Combination With BVL-GSK098 (BETO)

Rifampicin- and Isoniazid-Susceptible Pulmonary Tuberculosis (TB)

South Africa
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); AIDS Clinical... and other collaborators

Recruiting

Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 703/HPTN 081 AMP Study

HIV Infection

Malawi, Botswana, South Africa, Zimbabwe
TASK Applied Science

Completed

BCG Vaccination for Healthcare Workers in COVID-19 Pandemic

COVID-19 | Sars-CoV2

South Africa
University of Cape Town
University of Stellenbosch; University of Cape Town Lung Institute; University... and other collaborators

Completed

An Open-label RCT to Evaluate a New Treatment Regimen for Patients With Multi-drug Resistant Tuberculosis (NEXT)

Tuberculosis | Multidrug Resistant Tuberculosis | Extensively-drug Resistant Tuberculosis

South Africa
Novavax
Bill and Melinda Gates Foundation

Completed

A Study Looking at the Effectiveness and Safety of a COVID-19 Vaccine in South African Adults

COVID-19 | SARS-CoV-2 Infection

South Africa
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment to Physician-Led RR-TB Treatment

Drug Resistant Tuberculosis

South Africa
Wits Health Consortium (Pty) Ltd
Perinatal HIV Research Unit of the University of the Witswatersrand; PharmaCentrix...

Terminated

PHRU CoV01 A Trial of Triazavirin (TZV) for the Treatment of Mild-moderate COVID-19 (PHRUCov01)

Covid19

South Africa
University of Cape Town

Withdrawn

Chloroquine Outpatient Treatment Evaluation for HIV-Covid-19 (CQOTE)

Covid-19 | HIV

South Africa
Imperial College London
University of Cape Town

Completed

Male Partner Involvement in the Prevention of MTCT of HIV

HIV Infections

South Africa
University of Cape Town

Completed

Linezolid, Aspirin and Enhanced Dose Rifampicin in HIV-TBM (LASER-TBM)

HIV-1-infection | Tuberculosis Meningitis

South Africa
AIDS Malignancy Consortium
National Cancer Institute (NCI); Montefiore Medical Center; University of Arkansas and other collaborators

Completed

Cisplatin and Radiation Therapy in Treating Patients With HIV-Associated Locally Advanced Cervical Cancer

Acquired Immunodeficiency Syndrome | Cervical Cancer

South Africa, Zimbabwe
University of Cape Town
University of KwaZulu

Unknown

African Covid-19 Critical Care Outcomes Study

Severe Acute Respiratory Syndrome Coronavirus 2

South Africa
Chris Hani Baragwanath Academic Hospital

Terminated

High Flow Oxygen Therapy vs Standard Care in Infants With Viral Bronchiolitis

Bronchiolitis, Viral

South Africa
University of Pretoria
University of Stellenbosch

Active, not recruiting

Effectiveness Study of Human Papilloma Virus (HPV) Vaccines to Prevent Recurrence of Genital Warts (TheraVACCS)

Genital Warts

South Africa
Qurient Co., Ltd.

Terminated

A Phase 2 Study to Evaluate Biomarker Change, Efficacy, Pharmacokinetics, Safety and Tolerability of Telacebec (Q203) in Covid-19 Patients

COVID-19 Virus Infection

South Africa
University of Liverpool
Radboud University Medical Center; University of Cape Town; UNITAID; Liverpool... and other collaborators

Completed

Dolutegravir in Pregnant HIV Mothers and Their Neonates (DolPHIN-2)

Pregnancy Related | HIV-1-infection

Uganda, South Africa
RTI International
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Medical Research...

Completed

Venue-Based Couples CoOp in South Africa (Couples CoOp)

HIV Infections | Alcoholism

South Africa
University of Washington
National Institute of Mental Health (NIMH)

Completed

Lotto to Link Study: A Prospective, Interventional, Randomized Study of Conditional Incentives

HIV Infections | Incentives | ART

South Africa
University of Witwatersrand, South Africa

Completed

The HIV Testing Trends and Outcomes at a Johannesburg Trauma ICU Unit

Outcome, Fatal

South Africa
Boston University
Vanderbilt University; University of Witwatersrand, South Africa

Completed

A Pilot Voucher Incentive for Improving Retention in Postpartum HIV Care in South Africa

HIV

South Africa
University of Exeter
University College, London; Medical Research Council, South Africa

Completed

Stepping Stones and Creating Futures Plus Pilot

Intimate Partner Violence | Poverty

South Africa
FHI 360
United States Agency for International Development (USAID); University of Witwatersrand...

Completed

Assessing Preference for 3 Female Condoms: A Comparative Evaluation of the PATH Woman's Condom, FC2 and the Reddy 6

Contraception

South Africa
Desmond Tutu HIV Foundation
National Institutes of Health (NIH); University of Cape Town; Zeteo Tech Incorporated

Completed

Bioaerosol Sampling in Suspected Pulmonary Tuberculosis

Pulmonary Tuberculosis Confirmation by Sputum Microscopy With or Without Culture

South Africa
Brown University
Rhode Island Hospital; Medical Research Council, South Africa

Completed

Integrated Prevention of HIV Risk and Intimate Partner Violence Among Adolescents in South Africa

Sexual Behavior | Intimate Partner Violence

South Africa
University of Stellenbosch
New York University

Recruiting

Pre- and Post-treatment Lung Microbiota, Metabolome and Immune Signatures at the Site of Disease in Patients With Active Pulmonary Tuberculosis (TB-LUNG)

HIV/AIDS | TB - Tuberculosis

South Africa
University of Cape Town
Wellcome Trust; Médecins Sans Frontières, Belgium

Completed

Tenofovir-lamivudine-dolutegravir Combination as Second-line ART: a Randomised Controlled Trial (ARTIST)

HIV Infections

South Africa
University of Cape Town
Desmond Tutu HIV Centre; Wits Reproductive Health and HIV Institute

Terminated

Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected Volunteers (Darifi)

HIV Infections

South Africa
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Essentiality of INH in TB Therapy

Tuberculosis

South Africa
Duke University
National Institute of Mental Health (NIMH); University of Cape Town

Completed

Improving the Health of South African Women With Traumatic Stress in HIV Care (ImpACT)

HIV | Trauma Exposure

South Africa
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Adults at Increased Risk for Pneumococcal Disease (V114-017/PNEU-DAY)

Pneumococcal Infections

United States, Australia, Canada, Chile, New Zealand, Poland, Russian Federation
Henry M. Jackson Foundation for the Advancement...
Johns Hopkins University; Karolinska Institutet; University of Miami; Chulalongkorn... and other collaborators

Active, not recruiting

Safety and Effects of Using Prime-boost HIVIS DNA and MVA-CMDR Vaccine Regimens With or Without Toll-like Receptor 4 Agonist on HIV Reservoirs in Perinatally HIV Infected Children and Youth (HVRRICANE)

HIV Infections

South Africa
University of Stellenbosch
University of Pittsburgh

Unknown

TB-IRIS NSAID Cox-2 Inhibitor Prevention Trial

Tuberculosis

South Africa
University of Stellenbosch
Columbia University; McMaster University

Active, not recruiting

Mobile Phone Text Messaging Plus Motivational Interviewing: Effects on Breastfeeding, Child Health Outcomes (MTM-MI)

HIV Infections | Breastfeeding, Exclusive

South Africa
University of Stellenbosch
University of British Columbia; McMaster University

Completed

Text Messaging Plus Motivational Interviewing in Promotion of Breastfeeding Among HIV-infected Women

HIV Infections | Breast Feeding

South Africa

Clinical Trials on Infections, Streptococcal in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ghana

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Rare Diseases

Drug Interventions

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