Clinical Trials on Inflammatory Response

Total 7514 results

Kantonsspital Winterthur KSW

Not yet recruiting

Regenerative Therapy With Autologous Stromal Vascular Fraction Derived Mesenchymal Stem Cells and Platelet-rich Plasma to Treat Complex Perianal Diseases

Perianal Crohn Disease | Perianal Fistula | Rectovaginal Fistula | Anal Fissure | Perianal Fistula Due to Crohn's Disease

Switzerland
Fresenius Kabi

Not yet recruiting

bIosimilar of aDalimumab, an European evAluation (IDEA)

Rheumatoid Arthritis | Crohn Disease | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylitis
Theravance Biopharma

Completed

First in Human SAD and MAD Study of Inhaled TD-0903, a Potential Treatment for ALI Associated With COVID-19

Acute Lung Injury (ALI) Associated With COVID-19 | Inflammatory Lung Conditions Associated With COVID-19

United Kingdom
Merck Sharp & Dohme LLC
Centocor, Inc.

Completed

Post Marketing Surveillance Study of Remicade in Patients With Chronic Inflammatory Diseases (P04840) (REMission)

Arthritis, Rheumatoid | Psoriasis | Crohn's Disease | Arthritis, Psoriatic | Spondylitis, Ankylosing
Shirley Ryan AbilityLab

Terminated

Efficacy of Gralise® for Chronic Pelvic Pain

Irritable Bowel Syndrome | Ulcerative Colitis | Pelvic Pain | Interstitial Cystitis | Prostatitis

United States
AbbVie (prior sponsor, Abbott)
Eisai Co., Ltd.

Completed

Surveillance of Humira Injection in Korean Patients

Rheumatoid Arthritis | Psoriasis | Crohn's Disease | Psoriatic Arthritis | Ankylosing Spondylitis

Korea, Republic of
Momentum Data
Optimum Patient Care

Completed

Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health

Schizophrenia | Inflammatory Bowel Diseases | Bipolar Disorder | Sleep Disturbance | Suicide, Attempted | Attention Deficit Hyperactivity Disorder | Post-traumatic Stress Disorder | Self Harm | Body Image Disorder | Eating Disorders | Adjustment Disorders | Anxiety Disorder | Depressive Episode | Behavioral Disorder | Psychological Disorder and other conditions

United Kingdom
faida agili
UR17DN02 : Autoimmune Diseases Research Unit

Unknown

Serologic Profile of SARS CoV2 in COVID-19 Patients With Systemic Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | SARS-CoV Infection | Sjogren's Syndrome | Sarcoidosis | Spondyloarthritis | Behçet Disease | Inflammatory Myopathy | Systemic Disease

Tunisia
University of Catanzaro
Azienda Ospedaliera Universitaria Policlinico; Azienda Sanitaria Provinciale... and other collaborators

Recruiting

Nutraceuticals and Functional Foods

Gastrointestinal Diseases | Skin Diseases | Immune System Diseases | Urologic Diseases | Pain, Acute | Pain, Chronic | Memory Disorders | Inflammatory Disease | Immune Defect | Systemic Disease | Infective Disorder

Italy
KU Leuven

Recruiting

Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)

Healthy Controls | IBS | Ulcerative Colitis, Active | Ulcerative Colitis, Remission (3a: With IBS Symptoms, 3b: Without IBS Symptoms) | Crohn's Disease, Active | Crohn's Disease, Remission (6a: With IBS Symptoms, 6b: Without IBS Symptoms)

Belgium
National Institute of Cancerología

Active, not recruiting

Effect of an Anti-inflammatory Diet on Patients With Cervical Cancer

Cervical Cancer | Diet Modification | Pelvic Inflammatory Disease | Radiation Toxicity | Uterine Cervical Neoplasm

Mexico
Hopital Nord Franche-Comte

Completed

Vaccination Against SARS-Cov2 (COVID-19) in Chronic Inflammatory Rheumatism and Factors Determining Its Decision. (VACCI-RIC)

Rheumatoid Arthritis | Spondyloarthritis

France
Novartis Pharmaceuticals

Terminated

A 3-arm Proof of Concept Study of AIN457, ACZ885 or Corticosteroids in Patients With Polymyalgia Rheumatica

Polymyalgia Rheumatica | Inflammatory Diseases

Germany, Italy, United States, United Kingdom
Clinical Hospital Colentina

Unknown

Multimodal Approach in IBD Patients (MAID)

Vitamin D Deficiency | Crohn's Disease | Ulcerative Colitis | Nonalcoholic Fatty Liver Disease (NAFLD)

Romania
NeuroActiva, Inc.

Unknown

Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831 (NEUROSIVIR)

Severe Acute Respiratory Syndrome | Covid19 | Corona Virus Infection | Severe Acute Respiratory Syndrome (SARS) Pneumonia | Neurodegeneration | Neuroinflammatory Response | Severe Acute Respiratory Infection | Severe Acute Respiratory Syndrome of Upper Respiratory Tract

United States
Marc Dall'Era, MD
National Cancer Institute (NCI); Janssen, LP

Recruiting

Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response Defects

BRCA1 Gene Mutation | BRCA2 Gene Mutation | Prostate Carcinoma | RAD51C Gene Mutation | BRIP1 Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CDK12 Gene Mutation | CHEK1 Gene Mutation | DNA Damage Response Gene Mutation | DNA Repair Gene Mutation | FANCA Gene Mutation and other conditions

United States
Fresenius Kabi, France

Recruiting

Assessment of Predictive Factors for Persistence of Treatment After Substitution of Reference Adalimumab With the Fresenius Kabi Adalimumab Biosimilar in Patients With Chronic Inflammatory Diseases (SAPHIR)

Rheumatoid Arthritis | Crohn Disease | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylitis

France
Imperial College London

Recruiting

Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting (EHD-Pred PK)

Vasculitis | Asthma | Thyroid Eye Disease | Inflammatory Disease | COPD Exacerbation Acute

United Kingdom
Fresenius Kabi

Completed

A Study of the Real-world Use of an Adalimumab Biosimilar and Evaluation of Nutritional Status on the Therapeutic Response (OPALE)

Rheumatoid Arthritis | Psoriasis | Crohn Disease | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylitis

France
O & O Alpan LLC

Unknown

Investigation of Immune Disorders and Deficiencies

Autoimmune Diseases | Hypogammaglobulinemia | Inflammatory Diseases | Primary Immune Deficiencies | Common Variable Immune Deficiencies

United States
Mayo Clinic
Endocyte

Completed

FolateScan in Autoimmune Disease

Multiple Sclerosis | Osteoarthritis | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Crohn's Disease

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer

Endometriosis | Cervical Carcinoma | Endometrial Carcinoma | Pelvic Inflammatory Disease

United States
University of Jena
Medical University Innsbruck

Completed

Effects of Kalydeco on Upper Airway and Paranasal Sinus Inflammation Measured by Nasal Lavage and on Symptoms (KPNSI)

Inflammatory Changes in Epithelial Lining Fluid Sampled Non-invasively by Nasal Lavage in CF Patients With G551D Receiving Kalydeco

Germany
Christian von Buchwald
Bispebjerg Hospital

Completed

NO Measurements in Screening for Asthma and OSA, in Patients With Severe Snoring

Snoring | Asthma | Obstructive Sleep Apnea | Inflammatory Disease | Airway Disease | Concomitant Disease

Denmark
Integra LifeSciences Corporation

Terminated

An Evaluation of SprayShield in Reducing Post-Operative Adhesion Formation Following Major Open Abdominal Surgery

Ulcerative Colitis | Familial Polyposis

United States
University Hospital, Limoges

Recruiting

Acceptability of Simultaneous Screening for Viral Hepatitis B, C and HIV Among Drug Users in Non-conventional Structures (SCANVIR)

Hepatitis C | Hepatitis C Virus Infection, Response to Therapy of | Addiction, Alcohol | Addiction Opiate | Transmission, Intravenous Drug Abuser

France
AstraZeneca

Active, not recruiting

Olaparib Tablets Maintenance Monotherapy Ovarian Cancer Patients After Complete or Partial Response to Platinum Chemotherapy (L-MOCA)

Relapsed Ovarian Cancer | Following Complete or Partial Response to Platinum Based Chemotherapy | Platinum Sensitive

China, Malaysia
AIO-Studien-gGmbH
Novartis Pharmaceuticals; Assign Data Management and Biostatistics GmbH

Completed

Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study (EVINEC)

Neuroendocrine Carcinoma, Grade 3 | Poorly Differentiated Malignant Neuroendocrine Carcinoma | Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3 | Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma]... and other conditions

Germany
Medical University of Warsaw

Recruiting

Possible Differences in HCC Course Depending on DAA Treatment

Liver Cirrhosis | Carcinoma, Hepatocellular | Hepatitis C, Chronic | Drug Effect | Hepatitis C Virus Infection, Response to Therapy of | Drug Side Effect

Poland
AstraZeneca
Merck Sharp & Dohme LLC; European Network of Gynaecological Oncological Trial... and other collaborators

Active, not recruiting

Olaparib Treatment in BRCA Mutated Ovarian Cancer Patients After Complete or Partial Response to Platinum Chemotherapy

Relapsed Ovarian Cancer | Following Complete or Partial Response to Platinum Based Chemotherapy | Platinum Sensitive | BRCA Mutated

Korea, Republic of, France, China, Italy, United States, Israel, United Kingdom, Canada, Japan, Germany, Brazil, Netherlands, Belgium, Poland, Australia, Russian Federation, Spain
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's Tyrosine Kinase Inhibitor (BTK-I)

Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | Safety and Tolerability | Compare SHINGRIX Vaccine Response Rates

United States
Rambam Health Care Campus

Recruiting

Management of Prelabor Rupture of the Membranes at Term

Chorioamnionitis | Cesarean Section Complications | Endometritis | Fetal Infection

Israel
Janssen Scientific Affairs, LLC

Completed

A Research Study to Bank Samples for Future Evaluation to Identify Biomarkers That Predispose Crohn's Disease and Ulcerative Colitis Patients to Develop Hepatosplenic T-Cell Lymphoma (HSTCL)

Hepatosplenic T-Cell Lymphoma

United States
Federal University of Juiz de Fora
Fundação de Amparo à Pesquisa do estado de Minas Gerais

Unknown

Effects of Supplementation of Vitamin D in Patients With Crohn's Disease

Fatigue | Muscle Weakness | Vitamin D Deficiency | Sarcopenia | Crohn Disease | Disorder of Bone Density and Structure, Unspecified

Brazil
CytoSorbents, Inc

Recruiting

CytOSorb TreatMent Of Critically Ill PatientS Registry (COSMOS)

Sepsis | Burns | Septic Shock | Trauma | Infectious Disease | Pancreatitis | Acute Respiratory Distress Syndrome | Liver Transplant; Complications | Drug Overdose | Acute Liver Failure | Cardiogenic Shock | Rhabdomyolysis | Acute on Chronic Liver Failure | Hemophagocytic Lymphohistiocytoses | Extracorporeal Life Support and other conditions

Spain, Italy, Germany, Portugal
Johns Hopkins University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

CHAMPS Study: Chronic HepAtitis C Management to ImProve OutcomeS (CHAMPS)

Human Immunodeficiency Virus | Hepatitis C Virus Infection, Response to Therapy of

United States
Essen Biotech

Not yet recruiting

Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE) (BAH242)

Autoimmune Diseases | Systemic Lupus Erythematosus | Systemic Sclerosis | Lupus Nephritis | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | Idiopathic Inflammatory Myopathies | Granulomatous Polyangiitis

China
Tuberculosis Research Centre, India
International Union Against Tuberculosis and Lung Diseases; Sarvodaya Charitable... and other collaborators

Active, not recruiting

Modified BPaL Regimen for Managing Pre-XDR TB and MDR (TI/NR) TB in India (mBPaL)

Pre-Extensively Drug-Resistant Pulmonary TB | Treatment Intolerant Multidrug-Resistant Pulmonary TB | Non-responsive Multidrug-Resistant Pulmonary TB

India
University of Sao Paulo General Hospital

Completed

Yellow Fever Vaccine in Patients With Rheumatic Diseases

Rheumatoid Arthritis | Systemic Sclerosis | Granulomatosis With Polyangiitis | Juvenile Idiopathic Arthritis | Sjogren's Syndrome | Takayasu Arteritis | Spondyloarthritis | Juvenile Dermatomyositis | Mixed Connective Tissue Disease | Systemic Lupus | Inflammatory Myopathy

Brazil
Atara Biotherapeutics

No longer available

Expanded Access Protocol for Tabelecleucel for Patients With Epstein-Barr Virus-Associated Viremia or Malignancies

Lymphoproliferative Disorders | Stem Cell Transplant Complications | Epstein-Barr Virus (EBV) Infections | EBV+ Associated Lymphoma | EBV+ Associated Post-transplant Lymphoproliferative Disease (EBV+ PTLD) | Epstein-Barr Viremia | Lymphoma, AIDS-related | Epstein-Barr Virus-associated Lymphoproliferative... and other conditions
Celltrion HealthCare France

Recruiting

Yuflyma® (Adalimumab), Patient Experience After Switching (YU-MATTER)

Rheumatoid Arthritis | Crohn Disease | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylarthritis | Axial Spondyloarthritis Without Radiographic Evidence of Ankylosing Spondylitis

France
Seoul National University Boramae Hospital
Dong-A ST Co., Ltd.

Not yet recruiting

Compare the Effect of Eupatilin and Rebamipide on the Prevention of Gastroenteropathy (CEERS)

Osteoarthritis | Rheumatoid Arthritis | Enteritis | Gastric Ulcer | Ankylosing Spondylitis | Other Musculoskeletal Disorder | NSAID-Associated Gastropathy | NSAID (Non-Steroidal Anti-Inflammatory Drug) Induced Enteropathy
Societe Francaise de Rhumatologie
Bordeaux PharmacoEpi

Recruiting

Observational Study in Patients Treated With JAK Inhibitors for Inflammatory Rheumatism (MAJIK) (MAJIK)

Rheumatoid Arthritis | Psoriatic Arthritis | Spondyloarthritis | Inflammatory Rheumatism

France
University of California, San Diego
UCB Pharma; The Organization of Teratology Information Specialists

Recruiting

OTIS Autoimmune Diseases in Pregnancy Project

Rheumatoid Arthritis | Psoriasis | Crohn's Disease | Psoriatic Arthritis | Ankylosing Spondylitis

United States
Takeda

Active, not recruiting

A Study of Surgical Interventions in Fistulizing Conditions

Fistula | Crohns Disease | Rectovaginal Fistula | Complex Perianal Fistula | Complex Cryptoglandular Fistula

United States, Netherlands, Belgium, Israel, Italy, United Kingdom, Czechia, Austria, Canada, France
UCB BIOSCIENCES, Inc.
PPD; Parexel

Completed

A Multicener, Postmarketing Study Evaluating the Transfer of Cimzia From the Mother to the Infant Via the Placenta (CRIB)

Rheumatoid Arthritis | Crohn's Disease | Psoriatic Arthritis | Ankylosing Spondylitis | Axial Spondyloarthritis (AxSpA) | Non-radiographic Evidence-AxSpA

Netherlands, Switzerland, United States, France
National Institute of Arthritis and Musculoskeletal...

Terminated

Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease

Nervous System Malformations | Urticaria | Papilledema | Arthropathy, Neurogenic

United States
Zimmer Biomet

Active, not recruiting

PMCF Study on the Safety and Performance of the Zimmer® Maxera™ Acetabular System in Total Hip Arthroplasty

Avascular Necrosis | Inflammatory Arthritis | Osteoarthritis, Hip | Congenital Hip Dysplasia | Post-traumatic; Arthrosis | Rheumatoid Arthritis With Adequate Bone Quality

Netherlands, Finland, Belgium, France, Spain, Australia, Canada, United Kingdom
National Institute of Allergy and Infectious Diseases...
Autoimmunity Centers of Excellence; Clinical Trials in Organ Transplantation...

Completed

COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C (PRISM)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) | Coronavirus Disease 2019 (COVID-19) | Multisystem Inflammatory Syndrome in Children (MIS-C)

United States
UCB Biopharma SRL

Completed

A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol) (CHERISH)

Rheumatoid Arthritis | Plaque Psoriasis | Crohn's Disease | Psoriatic Arthritis | Axial Spondyloarthritis

United States, France, Germany, Spain, Switzerland, Netherlands

Clinical Trials on Inflammatory Response

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