Clinical Trials on Inherited Metabolic Disorders IMD

Total 39048 results

University Hospital, Gentofte, Copenhagen

Recruiting

The Role of Oxytocin in Regulating Blood Glucose (GLOXY-1)

Glucose Metabolism Disorders (Including Diabetes Mellitus)

Denmark
University of Pittsburgh
Bristol-Myers Squibb

Terminated

Study of Aripiprazole to Reduce Medical Risks in Bipolar Disorder

Metabolic Syndrome | Bipolar Disorder

United States
Medical University of Gdansk
Gdansk University of Physical Education and Sport

Not yet recruiting

Supplementation With Altha-aminoacids and Systemiec Inflammatory Response in Long-distance Runners.

Iron Metabolism Disorders | Inflammatory Response | Exercise Myoglobinuria | Citrulline; Metabolic Disorder

Poland
Laval University
Université de Montréal; Centre de Recheche du Centre Hospitalier Université...

Recruiting

Unravelling the Impact of Diet on Cardiovascular Health in Heterozygous Familial Hypercholesterolemia. (FH-Diet)

Cardiovascular Diseases | Familial Hypercholesterolemia | Cholesterol, Elevated | Nutrition, Healthy | Cholesterol; Metabolic Disorder

Canada
University of Aberdeen

Active, not recruiting

Acute Study of Anthocyanin-rich Bilberry and Polyphenol-rich Apple Extracts on Postprandial Glycaemic Response

Glucose Metabolism Disorders | Glucose Intolerance

United Kingdom
University of Aarhus
University of Copenhagen

Completed

Acute Metabolic Effects of Melatonin Treatment

Glucose Metabolism Disorders

Denmark
Instituto Aragones de Ciencias de la Salud

Completed

Effect of Therapeutic Phlebotomies on the Triglycerides Concentration in Patients With Hypertriglyceridemia and Hyperferritinemia

Hypertriglyceridemia | Hyperferritinemia

Spain
Maastricht University Medical Center
Unilever R&D

Completed

Alpha-linolenic Acid and Blood Pressure (VASALA)

Hypertension | Lipid Metabolism Disorders

Netherlands
Stanford University
American Diabetes Association

Completed

Insulin Resistance in Patients With Major Depression

Depressive Disorder | Depression | Mood Disorders | Insulin Resistance | Bipolar Disorder | Depressive Disorder, Major

United States
Oslo University Hospital
Pharmalogica; Wearnes Biotech @ Medicals; Beijing Peking University WBL Biotech...

Completed

The Effect of Hypocol® on Lipids in Subjects With Mild Hypercholesterolemia and Mildly Elevated Blood Glucose

Glucose Metabolism Disorders | Hyperlipidemia

Norway
Cairo University

Unknown

Prevalence of the Signs and Symptoms of TMD in Adolescents

TMD | TMJ Disorder

Egypt
Amsterdam UMC, location VUmc
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Evaluating the Effectiveness of the GILL eHealth Intervention to Improve Physical Health and Lifestyle Behaviours in Patients With Severe Mental Illness (GILL)

Metabolic Syndrome | eHealth | Lifestyle | Severe Mental Disorder | Somatic Screening
University of Cadiz
Ministerio de Ciencia e Innovación, Spain

Not yet recruiting

Physical Exercise, Diet, and Health in People With Type 2 Diabetes: Longitudinal Design of the EDUGUTION Study

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Fat Burn | Metabolism Disorder
University of Cadiz
Ministerio de Ciencia e Innovación, Spain

Recruiting

Efficacy of a Nutritional Education Strategy and Physical Exercise on the Gut Microbiota in Type 2 Diabetics (EDUGUTION)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Fat Burn | Metabolism Disorder

Spain
Virginia Commonwealth University
CSL Behring

Completed

Correlation Between Vitamin D Status and Bone Mineral Density in Patients With Hemophilia

Hemophilia A | Hemophilia B | Vitamin D Deficiency

United States
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Trial Comparing the Effects of Aripiprazole With Those of Standard of Care on Non-HDL Cholesterol in Patients With Schizophrenia or Bipolar I Disorder Who Have Metabolic Syndrome

Schizophrenia | Schizoaffective Disorder | Metabolic Syndrome | Bipolar I Disorder

Canada
University of California, San Francisco

Recruiting

Diet and Depression

Depression | Obesity | Metabolic Syndrome | Weight Gain | Major Depressive Disorder

United States
Centre for Addiction and Mental Health

Recruiting

Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents

Depression | Major Depressive Disorder

Canada
Hvidovre University Hospital
Rigshospitalet, Denmark; Herlev Hospital

Recruiting

COLONIC RESECTION FOR CANCER AS DIABETOGENIC RISK FACTOR (COLECDIAB)

Glucose Metabolism Disorders | Surgery | Colon Cancer | Chemotherapy Effect

Denmark
Azienda Ospedaliero, Universitaria Pisana

Enrolling by invitation

Effects on Glucose Homeostasis of Changes in Plasma Lipoproteins Induced by Nutritional and Pharmacologic Strategies

Glucose Metabolism Disorders

Italy
Zydus Lifesciences Limited

Terminated

A Clinical Study to Evaluate the Safety,Tolerability and PK of ZYT1, Following Oral Administration in Healthy Volunteers

Obesity | Lipid Disorders

India
Leiden University Medical Center
Dutch Diabetes Research Foundation

Completed

Metabolic Effects of Subchronic Dopamine D2 Receptor Blockade by Haloperidol in Healthy Humans

Insulin Resistance | Dyslipidemia

Netherlands
Puerta de Hierro University Hospital
Nutrition and Food Science Area, Faculty of Pharmacy, University of Valencia and other collaborators

Unknown

Effect of β-cryptoxanthin (β-Cx), Plant Sterols and Galactooligosaccharides on Systemic and Gastrointestinal Markers

Hypercholesterolemia | Osteoporosis | Postmenopausal Disorder
Ataturk University

Completed

Effects of Lansoprazole on Bone Turnover Markers

Calcium Metabolism Disorders | Bone Turnover Rate Disorder

Turkey
University of Pisa

Completed

To Determine the Effect of GLP1 on Cognitive Function, Brain Glucose Metabolism and Neuroplasticity.

Glucose Metabolism Disorders | Obesity | Degenerative Brain Disorder

Italy
Novo Nordisk A/S

Completed

Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus

Obesity | Metabolism and Nutrition Disorder

United States, Israel, Russian Federation, United Kingdom, Canada, Belgium, Germany, Australia
Taipei Veterans General Hospital, Taiwan

Unknown

The Roles of SAH Gene Family in Athrogenic Dyslipidemia in Postmenopausal Women (MOSAH-S2)

Dyslipidemia | Disorder Associated With Menstruation and/or Menopause

Taiwan
Bezmialem Vakif University

Completed

Bone Mineral Density, Disease Duration, and Activity in Ankylosing Spondylitis

Osteoporosis | Ankylosing Spondylitis | BMD

Turkey
Baylor College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Causal Mechanisms in Adolescent Arterial Stiffness

Metabolic Syndrome | Dyslipidemias | Pediatric Obesity | Lipid Disorder | Aortic Stiffness | Insulin Resistance Syndrome

United States
Genzyme, a Sanofi Company

Completed

Late-Onset Treatment Study Extension Protocol

Glycogen Storage Disease Type II (GSD-II) | Pompe Disease (Late-Onset) | Glycogenesis Type II | Acid Maltase Deficiency (AMD)

United States, France, Canada, Netherlands, Australia
Tri-Service General Hospital

Completed

Sarcopenia and Osteoporosis in the Patients With Hemophilia

Hemophilia | Sarcopenia | Hemophilic Arthropathy | Osteoporosis, Osteopenia

Taiwan
Rennes University Hospital
Ministry of Health, France

Completed

Cytochrome P450 2E1 and Iron Overload

Insulin Resistance | Iron Overload

France
University of Leipzig
Institut für Gesundheits- und Praxismanagement GmbH

Withdrawn

Pioglitazone in Impaired Glucose Tolerance

Glucose Metabolism Disorders

Germany
Leiden University Medical Center
Dutch Diabetes Research Foundation

Completed

Metabolic Effects of Subchronic Dopamine D2 Receptor Blockade by Antipsychotic Drugs in Healthy Humans

Insulin Resistance | Dyslipidemia

Netherlands
Istituto Ortopedico Galeazzi

Recruiting

METabolism After Orthopedic Surgery

Orthopedic Disorder | Metabolism and Nutrition Disorder

Italy
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Academisch...

Recruiting

Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance Phenotypes

Insulin Resistance | Hypertriglyceridemia

Netherlands
Radiant Research

Completed

Colesevelam Treatment for Impaired Fasting Glucose During Niacin Therapy (CERTAIN)

Hyperglycemia | Dyslipidemia | Hyperlipidemia

United States
Loughborough University

Active, not recruiting

CBD, Nutrient Metabolism and Energy Intake

Lipid Metabolism Disorders | Appetitive Behavior | Glucose Metabolism Disorders (Including Diabetes Mellitus)

United Kingdom
Baxalta now part of Shire

Terminated

Osteoporosis and MRI Study in Hemophilia

Hemophilia A | Hemophilia B | Bone Mineral Density

United States
Oklahoma State University

Completed

The Reproducibility and Clinical Utility of an Abbreviated Fat Tolerance Test

Metabolic Syndrome | Dyslipidemias

United States
University of California, Davis
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Metabolic Effects of Consuming Sugar-Sweetened Beverages for Two Weeks (DRS)

Metabolic Syndrome | Insulin Resistance | Dyslipidemia

United States
AstraZeneca

Completed

Study of High Density Lipoprotein Cholesterol (HDL-C)-Raising Mechanism of Rosuvastatin (CRESTOR™) by Quantifying the Key Steps of Reverse Cholesterol Transport (RCT)

Metabolic Syndrome | Dyslipidemia

Australia
University of Pisa

Recruiting

Treatment Outcomes in Patients With Muscular Temporo-mandibular Joint Disorders

TMD | TMD/Orofacial Pain

Italy
University of Messina

Completed

Inofolic NRT and the Metabolic Syndrome

Metabolic Syndrome | Postmenopausal Disorder

Italy
The Hospital for Sick Children

Recruiting

Adaptive Optics Retinal Imaging in Inherited and Acquired Retinal Disorders

Genetic Disease | Inherited Disease

Canada
The Hospital for Sick Children
Canadian Hemophilia Society

Completed

An Institutional Pilot Study to Investigate Physical Activity Patterns in Boys With Hemophilia (HEPS)

Hemophilia A | Hemophilia B | Factor IX Deficiency | Factor VIII Deficiency

Canada
UMC Utrecht

Unknown

Cardiovascular Disease (CVD) in Haemophilia

Cardiovascular Disease | Haemophilia

Netherlands, United Kingdom
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
Yu Chen

Recruiting

A Clinical Study to Evaluate the Effects of Akkermansia Muciniphila on Insulin Resistance Among Obese Subjects.

Obesity Associated Disorder

China
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction

Clinical Trials on Inherited Metabolic Disorders IMD

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