Clinical Trials on Invasive Fungal Infection

Total 61761 results

Duke University
Pfizer

Completed

β-D-Glucan (BDG) Surveillance With Preemptive Anidulafungin vs. Standard Care for Invasive Candidiasis in Surgical Intensive Care Unit (SICU) Patients

Invasive Candidiasis

United States
University of Cologne

Recruiting

ECMM Candida Registry - CandiReg (CandiReg)

Invasive Candidiases

Germany
St. Anna Kinderkrebsforschung

Completed

Optimized Diagnostics for Improved Therapy Stratification in Invasive Fungal Infections (FUNGITECT)

Systemic Mycosis

Austria, Netherlands, Russian Federation
Instituto de Investigación Hospital Universitario...

Unknown

Effectiveness and Efficiency of a Voriconazole Preemptive Genotyping Strategy (VORIGENPHARM)

Invasive Fungal Infections

Spain
Merck Sharp & Dohme LLC

Completed

Open Label Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P00041)

Mycoses
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of ABCD for Injection in Subjects With Invasive Candidiasis and Invasive Aspergillus

Invasive Aspergillosis | Invasive Candidiasis

China
University Hospital, Lille

Recruiting

Early Discontinuation of Empirical Antifungal Therapy and Biomarkers (SEAT)

Invasive Candidiasis

France
University Hospital, Limoges

Completed

Pharmacokinetics of Micafungin in Patients of Intensive Care Units (MI-K)

Invasive Candidiasis

France
University Medical Center Groningen

Completed

Variability of Fluconazole Concentration in Critically Ill Patients

Invasive Candidiasis

Netherlands
Merck Sharp & Dohme LLC

Completed

A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of an Antifungal Drug in the Treatment of Fungal Infections in Adults (0991-801)(COMPLETED)

Invasive Candidiasis
Merck Sharp & Dohme LLC
Mycoses Study Group

Terminated

Pilot Feasibility Study With Patients Who Are at High Risk For Developing Invasive Candidiasis in a Critical Care Setting (MK-0991-067)

Invasive Candidiasis
University Hospital, Grenoble

Completed

Empirical Antifungal Treatment in ICUS (EMPIRICUS)

Invasive Candidiasis

France
Mycoses Study Group
Merck Sharp & Dohme LLC

Completed

Randomized Study of Caspofungin Prophylaxis Followed by Pre-emptive Therapy for Invasive Candidiasis in the Intensive Care Unit (ICU) (MSG-01)

Invasive Candidiasis

United States
Merck Sharp & Dohme LLC

Completed

Post-marketing Surveillance Study of Invasive Mycosis With Posaconazole (Study P04641)

Mycoses
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis (MK-5592-069)

Invasive Pulmonary Aspergillosis | Fungal Infections
Lin Chen

Completed

Aspergillosis Detection Via EBC-GM in Ventilated Patients

Critical Illness | Aspergillosis, Invasive Pulmonary | Exhaled Breath Condensate | Bronchoalveolar Lavage Fluid | Respiration Failure | Sensitivity and Specificity | Respiratory Fungal Infection

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Unknown

Amphotericin B Cholesteryl Sulfate Complex for Injection(ABCD) in the Treatment of Invasive Candidiasis and Invasive Aspergillosis

Invasive Aspergillosis | Invasive Candidiasis
Yung Shin Pharm. Ind. Co., Ltd.

Completed

Evaluate Bioequivalence of Micafungin (50mg/Vial)

Invasive Candidiasis

Taiwan
Duke University
Children's Hospital of Philadelphia

Completed

BIOPIC: Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia (BIOPIC)

Invasive Candidiasis

United States, Saudi Arabia, Greece, Spain
Merck Sharp & Dohme LLC

Terminated

Safety, Tolerability, and Efficacy of Caspofungin Versus Amphotericin B Deoxycholate in the Treatment of Invasive Candidiasis in Neonates and Infants (MK-0991-064)

Candidiasis, Invasive
Hasan Al-Dorzi
King Fahad Medical City

Completed

Invasive Candidiasis in Saudi ICUs (ICIP-SA)

Invasive Candidiasis

Saudi Arabia
Pfizer
Vicuron Pharmaceuticals

Completed

The Safety and Effectiveness of Intravenous Anidulafungin as a Treatment for Patients With Invasive Candidiasis.

Candidiasis

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Voriconazole and Caspofungin Acetate in Treating Invasive Fungal Infections in Patients With Weakened Immune Systems

Unspecified Adult Solid Tumor, Protocol Specific | Infection

United States
Centre Hospitalier Universitaire Dijon

Completed

Evaluate the Performance of Genetic Amplification by Polymerase Chain Reaction (PCR) and the "Mannan Antigenemia and Antimannan Antibodies Couple as a Means of Diagnosis and a Marker of Follow-up in Invasive Candidiasis. (EMPIRICAND)

Invasive Candidiasis; Treatment With Echinocandin

France
Charite University, Berlin, Germany

Completed

Perception and Prevalence of Fungal Infections in Berlin - Brandenburg (IFI_ICU)

Invasive Mycosis

Germany
University Hospital Ostrava
Municipal Hospital Ostrava; University Hospital Olomouc; University of Ostrava; Public Health Institute Ostrava and other collaborators

Recruiting

Early Diagnosis of Invasive Lung Aspergillosis

Invasive Pulmonary Aspergillosis | Respiratory Infection

Czechia
Astellas Pharma Inc
Basilea Pharmaceutica

Completed

Isavuconazole (BAL8557) in the Treatment of Candidemia and Other Invasive Candida Infections

Mycoses | Candidemia | Candidiasis, Invasive

Philippines, New Zealand, United States, Spain, Belgium, Canada, Israel, Malaysia, Mexico, Italy, Australia, Germany, Singapore, Hungary, Brazil, Thailand, China, India, Argentina, France, Russian Federation, Chile, Lebanon, South Africa and more
Asan Medical Center
Astellas Pharma Korea, Inc.

Unknown

Micafungin Prevention Study for Fungal Disease in Child Receiving Allogenic Hematopoietic Stem Cell Transplantation

Neutropenia | Hematopoietic Stem Cell Transplantation | Invasive Fungal Disease

Korea, Republic of
Astellas Pharma Inc

Completed

A Study to Evaluate Pre-emptive Treatment for Invasive Candidiasis in High Risk Surgical Subjects (INTENSE)

Mycoses

Belgium, Germany, Spain, France, Italy, Turkey, Austria, Switzerland, Hungary, United Kingdom, Israel, Denmark, Greece, Finland, Romania
TFF Pharmaceuticals, Inc.

Available

Voriconazole Inhalation Powder for the Treatment of Pulmonary Aspergillosis

Invasive Pulmonary Aspergillosis | Allergic Bronchopulmonary Aspergillosis | Chronic Pulmonary Aspergillosis | Pulmonary Fungal Infection | Aspergillus Tracheobronchitis | Anastomotic Infection
Astellas Pharma Inc

Completed

A Study to Compare Efficacy and Safety of Mycamine® and Itraconazole for Preventing Fungal Infections

Fungemia | Fungal Infections

China
Robert Krause, MD

Completed

Candida Spp. in the Lower Respiratory Tract: Harmless Residents or Pathogen?

Invasive Candidiasis | Pulmonary Candidiasis

Austria
National Cancer Institute (NCI)

Completed

Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients

Mycoses | Candidiasis | Fungemia | Aspergillosis

United States
Shanghai General Hospital, Shanghai Jiao Tong University...

Not yet recruiting

To Evaluate the Efficacy and Safety of Micafungin in Preventing Invasive Mycosis After Liver Transplantation

Liver Transplantation
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Application of an Electronic Nose in the Early Detection of ASpergillosis (AENEAS)

Pulmonary Invasive Aspergillosis

Netherlands
Gilead Sciences

Completed

Prevention of Invasive Fungal Infections (IFIs) in Subjects Receiving Chemotherapy for Acute Lymphoblastic Leukemia (AmBiGuard)

Invasive Fungal Disease

United Kingdom
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Research of New Serological Markers for the Diagnosis and Monitoring of Candidaemia in Hospitalized Patients (2419)

Candida Infection

Italy
Merck Sharp & Dohme LLC
Federal University of São Paulo

Completed

A Laboratory-based Surveillance Study of Candida Bloodstream Infections (MK-0991-093)

Candidemia
Universidade Federal do Rio de Janeiro
Federal University of São Paulo

Terminated

Validation of an Index of Neutropenia (D-index) in Febrile Neutropenic Cancer Patients (Dindexval)

Invasive Fungal Infections | Invasive Aspergillosis | Invasive Fusariosis

Brazil
Basilea Pharmaceutica

Terminated

Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds (AEGIS)

Invasive Fungal Infections

Israel, Germany, United States, Belgium
M.D. Anderson Cancer Center
Enzon Pharmaceuticals, Inc.

Completed

Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC)

Invasive Fungal Infections | Hematologic Malignancies

United States
Northern Italy Leukemia Group

Completed

Prophylaxis of Fungal Invasive Infections in Leukemia (PROFIL-C)

Invasive Pulmonary Aspergillosis

Italy
Shanghai Jiao Tong University School of Medicine

Unknown

Caspofungin Based Combined Anti-fungal Therapy for Proven or Probable Invasive Fungal Infection

Leukemia | Transplantation, Hematopoietic Stem Cell

China
Karius, Inc.
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Evaluation of NGS for Detection and Follow-up of Fungal Pathogens in Immunocompromised Pediatric Patients

Invasive Fungal Infections | Immunocompromised | Invasive Fungal Disease | Fever and Neutropenia

United States
University Hospital, Strasbourg, France

Unknown

Fungal Infection on a Joint Prosthesis

Fongal Infection
HelixBind, Inc.

Unknown

Assessment of Assay for Rapid Identification of Bloodstream Infections From Whole Blood

Candidemia | Bacteremia

United States
Mahidol University

Completed

Topical Amphotericin B in 30% Dimethylsulphoxide in Treating of Non-dermatophytes Onychomycosis (amphotericin)

Fungal Infection | Onychomycosis | Fungus, Nail

Thailand
Queen Fabiola Children's University Hospital
Merck Sharp & Dohme LLC

Terminated

New Biomarkers for Invasive Fungal Infections in Paediatric Haemato-oncology

Haemato-oncological Paediatric Patients Under Intensive Chemotherapy
University Medical Center Groningen

Completed

Pharmacokinetics of Micafungin in Critically Ill Patients

Critical Illness | Invasive Candidiasis

Netherlands
Merck Sharp & Dohme LLC

Completed

A Study of Caspofungin (MK-0991) in Japanese Children and Adolescents With Documented Candida or Aspergillus Infections (MK-0991-074)

Candidiasis, Invasive | Aspergillosis | Candidiasis, Esophageal

Clinical Trials on Invasive Fungal Infection

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