Clinical Trials on Joint Dysfunction

Total 19862 results

University of Colorado, Denver
The Hospital for Sick Children; Karolinska Institutet; The University of Texas... and other collaborators

Completed

Prospective Maternal Surveillance of SSA (Sjögren Syndrome A) Positive Pregnancies Using a Hand-held Fetal Heart Rate Monitor

Sjogren's Syndrome | Neonatal Systemic Lupus Erythematosus | Fetal Heart Block Complete

United States
UCB BIOSCIENCES, Inc.
Syneos Health; Parexel

Terminated

UCB Cimzia Pregnancy Follow-up Study

Rheumatoid Arthritis (RA) | Crohn's Disease (CD) | Psoriatic Arthritis (PsA) | Axial Spondyloarthritis and Ankylosing Spondylitis

United States
Mei changlin

Unknown

Radiofrequency Ablation for ADPKD Blood Pressure and Disease Progression Control (RAFALE)

Hypertension | Autosomal Dominant Polycystic Kidney Disease

China
University College, London
Washington University School of Medicine; University of Washington; Alzheimer... and other collaborators

Not yet recruiting

A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK (NIO-SILK)

Alzheimer Disease | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder) | Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)
Changchun GeneScience Pharmaceutical Co., Ltd.
West China Hospital

Not yet recruiting

A Randomized, Double-blind, Placebo-controlled Phase II Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic Profile of Genakumab Injection in Patients With Connective Tissue Disease-associated Interstitial Lung Disease

Systemic Sclerosis Associated Interstitial Lung Disease | Rheumatoid Arthritis Associated Interstitial Lung Disease (RA-ILD) | Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)

China
McGill University
Canadian Institutes of Health Research (CIHR); McMaster University; Drexel University

Not yet recruiting

Downstream Effects of Personalized 'Top-down' Participation-based Interventions Among Youth With Physical Disabilities

Cerebral Palsy | Amputation | Spinal Cord Injuries | Spina Bifida | Musculoskeletal Disorder | Juvenile Arthritis

Canada
Tsung-Ying Li

Recruiting

Vitamin D Deficiency and Body Composition in the Patients With Hemophilia

Hemophilia | Vitamin D Deficiency | Body Composition | Sarcopenia | Osteoporosis | Hemophilic Arthropathy

Taiwan
Radboud University Medical Center

Recruiting

Assessment of Treatment With Laparoscopic Fenestration or Aspiration Sclerotherapy for Large Symptomatic Hepatic Cysts (ATLAS)

Autosomal Dominant Polycystic Kidney | Polycystic Liver Disease | Liver Cyst | Autosomal Dominant Polycystic Liver Disease

Netherlands
Newcastle-upon-Tyne Hospitals NHS Trust

Recruiting

Global Registry for COL6-related Dystrophies

Bethlem Myopathy | Ullrich Congenital Muscular Dystrophy 1, Digenic, Col6A1/Col6A2 | Ullrich Congenital Muscular Dystrophy 1, Autosomal Recessive | Ullrich Congenital Muscular Dystrophy 1, Autosomal Dominant | Bethlem Myopathy 1, Autosomal Recessive | UCMD | BTHLM1

United Kingdom
Jonsson Comprehensive Cancer Center
Eli Lilly and Company; Genentech, Inc.

Active, not recruiting

Necitumumab and Trastuzumab in Combination With Osimertinib for the Treatment of Refractory Epidermal Growth Factor Receptor (EGFR)-Mutated Stage IV Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Refractory Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer American Joint Committee on Cancer (AJCC) v8 | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8

United States
Zimmer Biomet

Active, not recruiting

TESS V3 Modular Total Shoulder System PMCF

Rheumatoid Arthritis | Osteonecrosis | Avascular Necrosis | Rotator Cuff Tears | Proximal Humeral Fracture | Osteoarthritis Shoulder | Rotator Cuff Tear Arthropathy | Rheumatoid Arthritis Shoulder | Revision | Malunion of Fracture, Shoulder Region

France
Biogen

Completed

A Real-world Study of Imraldi® Use (PROPER)

Arthritis, Rheumatoid (RA) | Arthritis, Psoriatic (PsA) | Crohn's Disease (CD) | Colitis, Ulcerative (UC) | Axial Spondyloarthritis (axSpA)

Italy, United Kingdom, Germany, Belgium, Spain, Ireland
University of Alberta

Completed

IMPACT: IMPact of Antimalarials on Covid-19 Infections in RAPPORT (IMPACT)

Rheumatoid Arthritis | Psoriatic Arthritis | Covid-19 Infection | Hydroxychloroquine

Canada
University Hospital, Lille
FAI²R (Auto-immune and auto-inflammatory rare diseases French network)

Terminated

Mental Health Consequences of COVID19 Infection in the French RMD Cohort (MentCovid19RMD)

Covid19 | Inflammatory Rheumatism | Systemic Autoimmune Disease | Auto Inflammatory Diseases

France
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Association Between Long-term Hydroxychloroquine Treatment and Outcome of a History of Symptoms Suggestive of COVID-19 Infection During the Epidemic Period in France in Patients With Autoimmune Disease (COVCALL)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | SARS-CoV-2 | Psoriatic Arthritis | Sjogren's Syndrome

France
CMC Ambroise Paré

Completed

Feasibility of Specific Anesthesia of the Forefoot Preserving the Sensitivity of the Heel for Foot Surgery (DISTIB)

Morton Neuroma | Ingrown Nail | Metatarsal Fracture | Foot Infection | Hallux Valgus and Bunion (Disorder) | Foot Wound

France
University Hospital, Lille
FAI²R (Auto-immune and auto-inflammatory rare diseases French network)

Unknown

Covid-19 in Patients With Chronic Inflammatory Rheumatism, Auto-immune or Auto-inflammatory Rare and Non-rare Diseases (covid19 fai2r)

Autoimmune Diseases | Sars-CoV2 | Chronic Inflammatory Rheumatism

France
Kanuni Sultan Suleyman Training and Research Hospital

Completed

Prevalence of Myofascial Pain Syndrome in Adolescent Idiopathic Scoliosis

Myofascial Pain Syndrome | Trigger Point Pain, Myofascial | Scoliosis; Adolescence | Physical Medicine and Rehabilitation

Turkey
Universidad de Zaragoza
Ministry of Health, Kuwait; Universidad San Jorge

Completed

A Comparative Study of Two Dry Needling Interventions for Plantar Heel Pain

Plantar Fascitis | Myofacial Pain Syndromes | Trigger Point Pain, Myofascial

Kuwait
University Hospital, Ghent
Groupe SEBBIN

Recruiting

Prospective Observational Study on SEBBIN Silicone Gel-filled Testicular Implants

Gender Dysphoria | Orchitis | Testicular Cancer | Prosthesis Durability | Testicular Torsion | Undescended Testes | Testicular Agenesis | Testicular Atrophy

Belgium
PYC Therapeutics

Not yet recruiting

SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew)

Autosomal Dominant Optic Atrophy | Kjer Optic Atrophy | OPA1 Gene Mutation | Hereditary Optic Atrophies
University Hospital, Strasbourg, France

Recruiting

Assessment of Physician Consideration of ePRO's, From Patients With Gout, Rheumatoid Arthritis, Sjogren's Syndrome or Systemic Lupus, on the Frequency of Therapeutic Adjustments (CAPTAIN)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Sjogren's Syndrome | Gout

France
Jamp Pharma Corporation

Recruiting

The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications. (EASE PAIN)

Rheumatoid Arthritis | Plaque Psoriasis | Crohn Disease | Ulcerative Colitis | Hidradenitis Suppurativa | Psoriatic Arthritis | Ankylosing Spondylitis

Canada
University of Erlangen-Nürnberg Medical School

Recruiting

Renal Denervation in ADPKD- RDN-ADPKD Study (RDN-ADPKD)

Autosomal Dominant Polycystic Kidney Disease | Uncontrolled Hypertension | Renal Denervation

Germany
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Study of Leukocyte Populations in Patients With Chronic Inflammatory (LIMA)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Sjogren's Syndrome | Spondyloarthritis | Chronic Inflammatory Rheumatism | Systemic Autoimmune Disease

France
ATI Holdings, LLC

Recruiting

ATI Evidence-based Guide Investigating Clinical Services (AEGIS)

Osteoarthritis | Knee Osteoarthritis | Carpal Tunnel Syndrome | Shoulder Impingement Syndrome | Sprain | Hip Osteoarthritis | Fracture | Spine Osteoarthritis

United States
Izmir Bakircay University

Completed

Factors Affecting Functionality in Breast Cancer Survivors

Breast Cancer | Breast Cancer Female | Breast Cancer Lymphedema | Pain, Shoulder | Breast Carcinoma in Situ | Hand Grasp

Turkey
Mayo Clinic

Completed

Pasireotide LAR in Severe Polycystic Liver Disease (SOM230)

Autosomal Dominant Polycystic Kidney Disease | Polycystic Liver Disease | Autosomal Dominant Polycystic Liver Disease | Somatostatin Analogs

United States
AbbVie
Raffeiner GmbH

Completed

Assessment of Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Plaque Psoriasis, Crohn's Disease and Ulcerative Colitis Patients´ Adherence Attitudes to Maintenance Therapy With a Scheduled Adalimumab Treatment in Routine Clinical Practice (Adherence)

Rheumatoid Arthritis | Plaque Psoriasis | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylitis | Crohn´s Disease
University of Sao Paulo

Unknown

Exercise in Sjogren, Myositis and Takayasu's Arteritis

Myositis | Primary Sjogren´s Syndrome

Brazil
Chongqing Precision Biotech Co., Ltd

Recruiting

Safety and Efficacy of CD19 Targeted CAR-T Therapy for Refractory Autoimmune Disease

Systemic Scleroderma | Dermatomyositis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | SLE (Systemic Lupus)

China
VA Office of Research and Development

Completed

CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat

Chronic Kidney Diseases | Gout

United States
University of Nottingham

Completed

Monitoring of Inflammatory Conditions

Rheumatoid Arthritis | Psoriasis | Crohn Disease | Inflammatory Arthritis | Ulcerative Colitis | Psoriatic Arthritis | Reactive Arthritis | Inflammatory Disease | System; Lupus Erythematosus

United Kingdom
Tan Tock Seng Hospital

Completed

Effectiveness of Specifically Optimized Off-the-counter Foot Orthosis for the Subtle Cavus Foot

Plantar Fasciitis | Achilles Tendinopathy | Insertional Achilles Tendinopathy | Metatarsalgia | Pes Cavus | Subtle Cavus Foot | Mechanical Foot Pains | Strain of Peroneal Tendon | Pes Cavus, Bilateral | Pes Cavovarus

Singapore
Allena Pharmaceuticals

Terminated

Phase IIa Study of ALLN-346 (Engineered Urate Oxidase) in Subjects With Hyperuricemia, Gout and Chronic Kidney Disease

Chronic Kidney Diseases | Hyperuricemia | Gout

United States
Henry Ford Health System

Terminated

Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients (STOP-NT)

Bacteremia | Endocarditis | Acute Bacterial Skin and Skin Structure Infections | Health Care Associated Pneumonia | Osteomyelitis/Septic Arthritis

United States
UCB Biopharma S.P.R.L.

Completed

Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Severely Active Crohn's Disease

Moderate and Severe Active Rheumatoid Arthritis | Active Psoriatic Arthritis | Active Ankylosing Spondylitis | Moderately to Severely Active Crohn's Disease

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Center for Complementary and Integrative Health (NCCIH)

Completed

A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss

Cancer | Chronic Obstructive Pulmonary Disease | Rheumatoid Arthritis | Chronic Heart Failure | Cancer Cachexia

United States
Seoul National University Hospital
Chonbuk National University Hospital; Chonnam National University Hospital; Korea... and other collaborators

Terminated

Study of Anti-Viral Prophylaxis for HBsAg(+) or HBcAb(+)/HBsAb(-) Patients Starting Anti-TNFα

Rheumatoid Arthritis | Chronic Hepatitis B | Juvenile Idiopathic Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis

Korea, Republic of
Academisch Medisch Centrum - Universiteit van Amsterdam...
Alrijne Hospital

Completed

Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis (STONE)

Kidney Diseases | Urologic Diseases | Kidney Calculi | Urinary Calculi | Urolithiasis | Stone Ureter | Stone, Kidney | Urinary Stone | Pyelonephritis | Hydronephrosis | Obstruction | Kidney Failure, Acute | Ureter Obstruction | Urinary Obstruction | Kidney Dysfunction | Kidney Insufficiency | Pyelonephritis Acute | Stone, Urinary and other conditions

Netherlands
Hospital del Mar Research Institute (IMIM)

Enrolling by invitation

The Clinical Impact of the Novel Alzheimer's Blood-based Biomarkers (PLASMAR)

Neurodegenerative Diseases | Cognitive Impairment | Dementia | Alzheimer Disease | Lewy Body Disease | Frontotemporal Dementia | Vascular Dementia

Spain
PersonGen BioTherapeutics (Suzhou) Co., Ltd.

Recruiting

Early Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases

Systemic Lupus Erythematosus | Systemic Sclerosis | Idiopathic Inflammatory Myopathies | Primary Sjögren Syndrome | IgG4 Related Disease

China
Jonsson Comprehensive Cancer Center

Recruiting

High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma (HYDRA)

Prostate Adenocarcinoma | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer American Joint Committee on...

United States
University of Minnesota

Recruiting

Post-contracture Release Radiation for Dupuytren's Disease

Dupuytren Contracture | Dupuytren Disease of Finger | Dupuytren's Disease | Dupuytren Disease of Palm and Finger | Dupuytrens Contracture of Both Hands | Dupuytren's Disease of Palm of Right Hand | Dupuytren's Disease of Palm of Left Hand | Dupuytren Contracture of Right Palm | Dupuytren Contracture... and other conditions

United States
NRG Oncology
National Cancer Institute (NCI)

Active, not recruiting

Testing Whether Treating Breast Cancer Metastases With Surgery or High-Dose Radiation Improves Survival

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Lymph Nodes | Metastatic Malignant Neoplasm in the Liver | Metastatic Breast Carcinoma | Metastatic Malignant Neoplasm in the Lung and other conditions

United States, Canada, Saudi Arabia, Korea, Republic of
Freeman-Sheldon Research Group, Inc.

Terminated

Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome (STOP-FSS)

Craniofacial Abnormalities | Arthrogryposis | Freeman-Sheldon Syndrome | Arthrogryposis Distal Type 2A | Whistling Face Syndrome | Craniocarpotarsal Dysplasia | Craniocarpotarsal Dystrophy | Freeman-Sheldon Syndrome Variant | Sheldon-Hall Syndrome | Arthrogryposis Distal Type 2B | Gordon Syndrome | Arthrogryposis... and other conditions

United States
University Hospital, Limoges

Completed

Selection of Patients With Chronic Inflammatory Rheumatism Requiring Management During the COVID-19 Pandemia (SePaRIC)

Covid19 | Rheumatoid Arthritis | Inflammatory Arthritis | Spondyloarthritis | Inflammatory Rheumatism

France
Indiana University

Completed

Iron Therapy for Autosomal Dominant Hypophosphatemic Rickets: A Pilot Project.

Autosomal Dominant Hypophosphatemic Rickets

United States
Stanford University

Completed

Question Prompt List for Common Hand Conditions

Ganglion Cysts | Carpal Tunnel Syndrome | Trigger Finger | Dupuytren Contracture | Trigger Thumb

United States
University of Southern California

Completed

Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery

Ganglion Cysts | Carpal Tunnel Syndrome | Dupuytren Contracture | Trigger Digit | De Quervain Disease

United States

Clinical Trials on Joint Dysfunction

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Turkmenistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations