Clinical Trials on Kirsten Rat Sarcoma in United Kingdom

Total 13617 results

Amgen

Recruiting

Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

Advanced Solid Tumors | Kirsten Rat Sarcoma (KRAS) pG12C Mutation

United States, Italy, Taiwan, Spain, United Kingdom, Australia, Austria, Germany, Belgium, Japan, Netherlands, Korea, Republic of, Canada
Onxeo
Spectrum Pharmaceuticals, Inc

Completed

A Phase I/II Clinical Trial of PXD101 in Combination With Doxorubicin in Patients With Soft Tissue Sarcomas

Dose Escalation: Solid Tumors | MTD: Soft Tissue Sarcomas

Denmark, United Kingdom
The Netherlands Cancer Institute
Royal Marsden NHS Foundation Trust

Terminated

Clinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma Patients (PASART-2)

Sarcoma | Soft Tissue Sarcomas

United Kingdom, Netherlands
AstraZeneca

Completed

The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).

Gastrointestinal Stromal Tumors | Soft Tissue Sarcomas

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarker Differences in Samples From Patients With Undifferentiated Sarcomas

Soft Tissue Sarcoma

United States
Royal Marsden NHS Foundation Trust
Merck KGaA, Darmstadt, Germany

Active, not recruiting

Phase I Study Compound 451238 and Radiotherapy in Soft-tissue Sarcoma

Soft-tissue Sarcoma

United Kingdom
Vanderbilt-Ingram Cancer Center

Recruiting

Hypofractionated Radiotherapy Followed by Surgical Resection in the Treatment of Soft Tissue Sarcomas

Soft Tissue Sarcomas

United States
NYU Langone Health
Bristol-Myers Squibb

Withdrawn

Study of Nivolumab With or Without Pazopanib in Metastatic or Unresectable Soft Tissue Sarcomas

Soft Tissue Sarcomas

United States
Jonathan Trent, MD, PhD
Merck Sharp & Dohme LLC; Pfizer

Completed

Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas

Alveolar Soft Part Sarcoma | Soft Tissue Sarcomas

United States
National Cancer Institute (NCI)

Completed

Cabozantinib for Adults With Advanced Soft Tissue Sarcoma

Refractory Soft Tissue Sarcomas

United States
Birmingham Women's and Children's NHS Foundation...

Completed

Indo-cyanine Green (ICG) in Paediatric Oncology MIS

Rhabdomyosarcoma | Metastatic Osteosarcoma | Pulmonary Metastasis | Metastatic Ewing Sarcoma | Pediatric Renal Tumor | Non-Rhabdo. Soft Tissue Sarcoma

United Kingdom
Royal Marsden NHS Foundation Trust

Recruiting

Predicting Radiotherapy Response and Toxicities in Soft Tissue Sarcoma of the Extremities - Cohort B (PredicT-B)

Soft Tissue Sarcoma of the Extremities

United Kingdom
M.D. Anderson Cancer Center
Aadi Bioscience

Not yet recruiting

A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

Leiomyosarcoma | Soft-tissue Sarcomas

United States
Imperial College London

Recruiting

Preliminary Assessment of Safety and Tolerability of Dostarlimab in Combination Antiretroviral Therapy (cART) Refractory HIV Associated Kaposi Sarcoma (STARKAP)

Refractory HIV Associated Kaposi Sarcoma

United Kingdom
National Cancer Institute (NCI)

Completed

Blood and Tissue Study of Patients in NIH Protocol 08-C-0800

Sarcomas

United States
University Hospitals, Leicester

Terminated

Genetic and Telomere Characteristics of High of Grade Soft Tissue Sarcomas

Soft Tissue Sarcoma

United Kingdom
Radboud University Medical Center
GlaxoSmithKline

Completed

Individualizing Pazopanib Therapy by exploRing the Role of Early Metabolic responsE and Drug Exposure as a preDICTor for Treatment Outcome in Patients With STS (PREDICT)

Sarcoma, Soft Tissue

United Kingdom, Netherlands
Celgene

Completed

Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors

Melanoma | Sarcoma, Soft Tissue | Cancer | Fibrosarcoma | Neuroblastoma | Osteogenic Sarcoma | Rhabdomyosarcoma | Neoplasm | Malignant Melanoma | Tumors | Histiocytoma | Dermatofibrosarcoma | Sarcoma, Ewing's | Neoplasia | Ewing's Sarcoma | Ewing's Tumor | Sarcomas, Epitheliod | Sarcoma, Spindle Cell | Clinical Oncology | Oncology,... and other conditions

United States, Canada, Spain, France, United Kingdom, Italy, Switzerland
Centre Leon Berard
Roche Pharma AG

Recruiting

Clinical and Biological Activity of an Anti-PD-L1 (Atezolizumab) in Operable Localised Soft Tissue Sarcomas Patients to be Treated With Radiotherapy (RT-Immune)

Sarcoma,Soft Tissue

France, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
AstraZeneca; University of Sheffield; Cancer Research UK; University of Birmingham and other collaborators

Terminated

A Study of Selumetinib in Patients With Kaposi's Sarcoma (SCART)

AIDS-related Kaposi's Sarcoma

United Kingdom
University Hospital Muenster
Medical Research Council

Unknown

Combination Chemotherapy Plus Surgery and Radiation Therapy in Treating Patients With Ewing's Sarcoma

Sarcoma

United Kingdom
Royal Marsden NHS Foundation Trust
Institute of Cancer Research, United Kingdom

Unknown

HRQoL in Advanced Soft Tissue Sarcoma Patients Treated With Chemotherapy.

Quality of Life

United Kingdom
Case Comprehensive Cancer Center

Recruiting

Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas

Relapsed Sarcomas

United States
AGC Biologics S.p.A.

Completed

Phase II Study of NGR-hTNF in Combination With Doxorubicin in Patients Affected by Soft Tissue Sarcomas.

Metastatic Adult Soft Tissue Sarcoma

France, Italy, United Kingdom
Istituto Ortopedico Rizzoli
Regione Emilia-Romagna

Completed

Assessment of MGMT Promoter Methylation in Advanced Ewing Sarcoma Treated With Temozolomide and Irinotecan (MGMTLiberati)

Ewing Sarcoma Family of Tumors

United Kingdom, Italy
University of Oxford
Astellas Pharma Inc; European Organisation for Research and Treatment of Cancer... and other collaborators

Completed

Eurosarc Trial of Linsitinib in Advanced Ewing Sarcoma (LINES)

Refractory Ewing Sarcoma | Relapsed Ewing Sarcoma

United Kingdom, Germany, Netherlands, Italy, France
NHS Greater Glasgow and Clyde

Terminated

Negative Pressure Dressing Therapy in Soft Tissue Sarcoma Surgery

Sarcoma | Wound Infection

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust

Unknown

A Trial of Cediranib in the Treatment of Patients With Alveolar Soft Part Sarcoma (CASPS) (CASPS)

Alveolar Soft-part Sarcoma

Australia, United Kingdom, Spain
European Organisation for Research and Treatment...

Terminated

Chemotherapy in Treating Patients With Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor

Sarcoma

United Kingdom
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

Phase 2 Study in Patients With MiT Tumors

Renal Cell Carcinoma (RCC) | Alveolar Soft Part Sarcoma (ASPS) | Clear Cell Sarcoma (CCS)

United States, Canada, United Kingdom
European Organisation for Research and Treatment...
Gynecologic Oncology Group; NHS Greater Glasgow and Clyde

Active, not recruiting

IRCI Gynae Sarcomas, High Grade Uterine Sarcoma

Uterine Sarcoma

France, Italy, Spain, Netherlands, United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma (GEMMK)

Sarcoma

United Kingdom
Incyte Corporation

Terminated

A Study of INCB059872 in Relapsed or Refractory Ewing Sarcoma

Relapsed Ewing Sarcoma

United States, Spain, United Kingdom, Italy
Sarcoma Alliance for Research through Collaboration

Completed

ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated, Incurable Ewing Sarcoma

Ewing Sarcoma

United States, United Kingdom
University College, London
Richard Scowcroft Foundation

Terminated

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?

Osteosarcoma | Spindle Cell Sarcoma of Bone

United Kingdom
European Organisation for Research and Treatment...
Boehringer Ingelheim

Terminated

Ph II Nintedanib vs. Ifosfamide in Soft Tissue Sarcoma (ANITA)

Sarcoma, Soft Tissue

France, Belgium, Poland, Spain, Lithuania, Netherlands, United Kingdom
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; M.D. Anderson Cancer Center; Merck Sharp & Dohme LLC; Dana-Farber Cancer Institute and other collaborators

Completed

Clinical Study of Vorinostat in Combination With Etoposide in Pediatric Patients < 21 Years at Diagnosis With Refractory Solid Tumors

Solid Tumors | Relapsed/Refractory Sarcomas

United States, Canada
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma (VORTEX)

Sarcoma

United Kingdom
Oxford University Hospitals NHS Trust
Surgical Intervention Trials Unit (trial oversight); NIHR Direct Delivery Team... and other collaborators

Recruiting

HIFU Ablation of Soft Tissue Sarcoma (SarcAblate)

Soft Tissue Sarcoma | Desmoid; Abdominal

United Kingdom
Institute of Cancer Research, United Kingdom
Royal Marsden NHS Foundation Trust; Cancer Research UK

Completed

Preoperative Imaging in Retroperitoneal Sarcoma (PIRS)

Cancer

United Kingdom
Epizyme, Inc.

Recruiting

Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma

Advanced Soft-tissue Sarcoma | Advanced Epithelioid Sarcoma

United States, Taiwan, Canada, United Kingdom
The Christie NHS Foundation Trust

Completed

MRI in Pre-operative Radiotherapy for Soft Tissue Sarcoma: MISTS Study

Sarcoma

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Recruiting

Novel Applications for Sarcoma Assessment (NASA)

Sarcoma

United Kingdom
University College, London
Cancer Research UK; NCRI Radiotherapy Trials QA (RTTQA) Group

Completed

A Study of IMRT in Primary Bone and Soft Tissue Sarcoma (IMRiS)

Ewing Sarcoma | Chordoma | Bone Sarcoma | Soft Tissue Sarcoma, Adult

United Kingdom, Ireland
Advenchen Laboratories, LLC

Active, not recruiting

Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS) (APROMISS)

Leiomyosarcoma | Synovial Sarcoma | Alveolar Soft Part Sarcoma | Soft-Tissue Sarcoma

United States, United Kingdom, Spain, China, Italy
European Organisation for Research and Treatment...
PharmaMar

Terminated

Trabectedin Maintenance Post 1st-line in STS

Sarcoma, Soft Tissue

France, Germany, Spain, Netherlands, Poland, United Kingdom
GlaxoSmithKline

Active, not recruiting

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma

Neoplasms

United States, Netherlands, Canada, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Pfizer; Cancer Research UK; University of Birmingham

Completed

A Study of Axitinib in Patients With Advanced Angiosarcoma and Other Soft Tissue Sarcomas (Axi-STS)

Soft Tissue Sarcoma

United Kingdom
GlaxoSmithKline

Completed

Pazopanib In Patients With Relapsed Or Refractory Soft Tissue Sarcoma

Sarcoma, Soft Tissue

Belgium, Netherlands, United Kingdom, France, Hungary
Pfizer

Completed

Study Of Anti-IGF-IR CP-751,871 In Patients With Solid Tumors

Sarcoma, Ewing's

United States, United Kingdom

Clinical Trials on Kirsten Rat Sarcoma in United Kingdom

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