Clinical Trials on LDL-hypercholesterolemia

Total 1296 results

AstraZeneca

Completed

A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With Dyslipidemia

Dyslipidemia | Hypercholesterolemia

United States
Takeda

Completed

Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.

Hypercholesterolemia

Poland, United Kingdom, Germany, South Africa, Finland, Estonia, Czech Republic
Kowa Research Europe

Completed

Study to Compare the Efficacy and Safety of Pitavastatin and Simvastatin

Dyslipidemia | Hypercholesterolemia

Finland, Italy, Norway, Russian Federation, United Kingdom
Chang Gung Memorial Hospital

Recruiting

Red Yeast Rice for Primary Prevention of Hypercholesterolemia

Hypercholesterolemia

Taiwan
Tianjin Medical University

Recruiting

Peripheral Treg Cell Senescence & Serum Total Cholesterol Level

Hypercholesterolemia

China
Organon and Co

Completed

Coadministration of Ezetimibe and Atorvastatin in Patients With Primary Hypercholesterolemia (P05456)

Hypercholesterolemia
Organon and Co

Completed

A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk (0653A-809)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)

Hypercholesterolemia
Organon and Co

Completed

To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 40 mg (0653-090)

Hypercholesterolemia
Organon and Co

Completed

A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED)

Hypercholesterolemia
Otsuka Pharmaceutical Co., Ltd.

Completed

A Dose-finding Trial of ETC-1002(Bempedoic Acid) in Patients With Hypercholesterolemia

Hypercholesterolemia

Japan
Organon and Co

Completed

Long-Term Safety and Tolerability of Ezetimibe (SCH 58235, MK-0653) With Atovastatin (P02154, MK-0653-017)

Hypercholesterolemia
Organon and Co

Completed

Ezetimibe Added to Statin Therapy (EASY) Study (0653-087)(COMPLETED)

Hypercholesterolemia
University of Bologna

Completed

Effect of a Dietary Supplement on Lipid Pattern and Liver Parameters in Hypercholesterolemia

Hypercholesterolemia

Italy
Kowa Company, Ltd.

Completed

K-924 Phase III Long Term Study

Hypercholesterolemia

Japan
French Cardiology Society
Fondation Coeur et Artères

Withdrawn

Effect of Phytosterols Enriched Products Consumption on Carotid Artery Artherosclerotic Plaque (PHYTOPLAQUES)

Hypercholesterolemia

France
Orient Pharma Co., Ltd.
Orient Europharma Co., Ltd.

Completed

Efficacy and Safety Study of Pitavastatin for Hypercholesterolemia

Hypercholesterolemia

Taiwan
The Cleveland Clinic
AstraZeneca

Completed

Supplements, Placebo, or Rosuvastatin Study (SPORT)

Hypercholesterolemia

United States
University of Manitoba
Manitoba Agri-Health Research Network

Completed

Validating the "Foods for Health" Portfolio of Functional Food Products

Hypercholesterolemia

United States, Canada
University of Alberta

Completed

Kefir Cholesterol Lowering Pilot Study

Hypercholesterolemia

Canada
Amgen

Completed

Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollment

Hypercholesterolemia

France, Germany, United States, Czechia, Italy, Australia, Spain, United Kingdom
Amgen

Completed

Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study (DESCARTES)

Hypercholesterolemia

United States, Denmark, Belgium, Czechia, Austria, Australia, Canada, Hungary, South Africa
JW Pharmaceutical

Completed

Efficacy and Safety Study of Pitavastatin Versus Atorvastatin to Treat Hypercholesterolemia (PITCH)

Hypercholesterolemia
Swisse Wellness Pty Ltd
Commonwealth Scientific & Industrial Research Organisation; BIONAP SRL

Completed

Investigating Effects of a Novel Nutraceutical on Hypercholesterolaemia in Australian Adults (CLoNE)

Hypercholesterolemia

Australia
Organon and Co

Completed

Effect Of Ezetimibe Coadministration With Simvastatin In A Middle Eastern Population: A Prospective, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial (0653-151)

Hypercholesterolemia
Organon and Co

Completed

To Evaluate the Lipid-Lowering Efficacy and Safety of Simvastatin 40 Mg Tablet In Patients With Hypercholesterolemia (0733-264)

Hypercholesterolemia

Taiwan
Organon and Co

Completed

Evaluation of Potential for Drug Interaction Between SCH 58235 (Ezetimibe) and Pitavastatin (Study P03962)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

Study of an Approved Drug With a Statin (a Medication That Lowers Cholesterol Levels) as Compared to Statin Therapy Alone in Patients With High Cholesterol (0653-040)

Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC; Schering-Plough

Completed

Effects of Vytorin Versus Placebo in Subjects With Primary Hypercholesterolemia (Study P04420)

Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)

Hypercholesterolemia
NMP Medical Research Institute
Aarogyam UK

Completed

Cholesterol Lowering Effect of Cardio-Complement, an Ayurveda Formulation

Hypercholesterolemia

India
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Bioequivalence Study Comparing A New 10 Mg Atorvastatin Tablet To A 10 Mg Atorvastatin Commercial Tablet

Hypercholesterolemia

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Bioequivalence Study On Pediatric Appropriate Formulation

Hypercholesterolemia

Singapore
Civi Biopharma, Inc.

Completed

Phase 2a Study to Assess CIVI 007 in Patients on a Background of Statin Therapy

Hypercholesterolemia

United States
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Single Ascending Dose Study of PCSK-9 Inhibitor (IBI306) in Healthy Subjects.

Hypercholesterolemia

China
Charite University, Berlin, Germany

Completed

Safety and Efficacy of Propionate for Reduction of LDL Cholesterol (PROPER-LDL)

Hypercholesterolemia

Germany
University of Saskatchewan
Heart and Stroke Foundation of Canada

Completed

Low Versus High-glycemic Index Post-exercise Diets for Improving Metabolism and Body Composition

Hypercholesterolemia

Canada
NeuroBo Pharmaceuticals Inc.

Completed

Effect of Gemcabene on the Pharmacokinetics of Simvastatin in Healthy Volunteers

Hypercholesterolemia
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II)

Hypercholesterolemia

United States, France, Italy, Germany, Spain, Canada, United Kingdom, Australia, Mexico
Université Catholique de Louvain
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Completed

Lipid-lowering Therapy Individualization

Hypercholesterolemia

Belgium
UAS Labs LLC

Completed

Efficacy of a LRC™ (L. Reuteri NCIMB 30242) Capsule on Managing Cholesterol in Adults

Hypercholesterolemia

Canada
University of Minnesota
National Center for Research Resources (NCRR)

Completed

Effects of Black Tea Intake on Serum Lipids

Hypercholesterolemia

United States
Esperion Therapeutics, Inc.

Completed

A Study of the Safety, Pharmacokinetic Drug Interaction and Efficacy of ETC-1002 and Atorvastatin in Subjects With Hypercholesterolemia

Hypercholesterolemia

United States
Esperion Therapeutics, Inc.
Medpace, Inc.

Completed

Evaluation of ETC-1002, Ezetimibe, and the Combination in Hypercholesterolemic Patients

Hypercholesterolemia

United States
Amgen

Completed

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound (GLAGOV)

Hypercholesterolemia

United States, Canada, Denmark, Germany, Italy, Netherlands, Spain, Sweden, Belgium, Taiwan, Russian Federation, France, Czechia, Mexico, Korea, Republic of, Australia, United Kingdom, Argentina, Israel, Hungary, South Africa, Greece and more
Pfizer

Completed

Dose Ranging Study Of Bococizumab (PF-04950615; RN316) In Hypercholesterolemic Japanese Subjects

Hypercholesterolemia

Japan
Pfizer

Completed

A Study To Assess The Safety Of PF-05335810 In Hypercholesterolemic Subjects

Hypercholesterolemia

United States
Eli Lilly and Company

Terminated

A Study of Evacetrapib (LY2484595) in Japanese Participants With Primary Hypercholesterolemia

Hypercholesterolemia

Japan
Pfizer

Terminated

Single Dose Study of PF-06815345 in Healthy Subjects

Hypercholesterolemia

Belgium
LIB Therapeutics LLC
Medpace, Inc.

Completed

Study to Evaluate the Safety, PK, and Pharmacodynamics of LIB003 (LIB003SAD)

Hypercholesterolemia

United States

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