Clinical Trials on LONGEVITY 1

Total 5656 results

University of Saskatchewan
Government of Canada; Vaccine Formulation Institute (VFI); Government of Saskatchewan and other collaborators

Completed

Clinical Trial to Study the COVAC-2 Booster Dose (for COVID-19) in Generally Healthy Adults.

Double Vaccinated for COVID-19 (For Phase 1 of the Study) | Acute Respiratory Syndrome Coronavirus 2 (For Phase 2 Exploratory Group)

Canada
AVROBIO

Terminated

Lentiviral Vector Gene Therapy - The Guard1 Trial of AVR-RD-02 for Subjects With Type 1 Gaucher Disease

Gaucher Disease

United States, Canada
Hadassah Medical Organization

Completed

A Second-generation AI Based Therapeutic Regimen in Patients With Gaucher Disease Treated With Enzyme Replacement Therapy.

Gaucher Disease Type 1

Israel
AVROBIO

Terminated

A Long-Term Follow-up Study of Subjects With Gaucher Disease Who Previously Received AVR-RD-02

Type 1 Gaucher Disease

United States, Canada
Columbia University
National Institutes of Health (NIH); National Institute on Aging (NIA)

Active, not recruiting

Anti-viral Therapy in Alzheimer's Disease

Alzheimer Disease | Herpes Simplex 2 | Herpes Simplex 1

United States
Shaare Zedek Medical Center

Completed

Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy

Gaucher Disease, Type 1

Israel
University of Virginia
DexCom, Inc.

Completed

Evaluation of Accuracy of Continuous Glucose Monitoring (CGM) in Patients With End Stage Renal Disease (ESRD) on Intermittent Hemodialysis (iHD).

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

United States
Instituto de Investigación Sanitaria de la Fundación...

Completed

The Benefits of Immediate Treatment Initiation Without Immunovirological Data Compared to Conventional BIC / FTC / TAF Treatment in Naive Patients With Type 1 HIV (Human Immunodeficiency Virus) Infection

HIV-1-infection

Spain
The Methodist Hospital Research Institute
Johns Hopkins University; University of Colorado, Denver; University of Pennsylvania and other collaborators

Active, not recruiting

Clinical Trial Readiness for SCA1 and SCA3 (READISCA)

Spinocerebellar Ataxia 3 | Spinocerebellar Ataxia Type 1

United States
CEN Biotech
Takeda; BioClinica, Inc.

Completed

Retrospective and Prospective Observational Study of MRI Changes in Bone and Visceral Lesions of Patients With Type 1 Gaucher Disease Treated With VPRIV® (Velaglucerase Alfa) (EIROS)

MRI | Gaucher Disease, Type 1

France
Shire

Completed

An Open-Label Extension Study of GA-GCB ERT in Patients With Type 1 Gaucher Disease

Gaucher Disease, Type 1

United States, Israel, Argentina, India, Korea, Republic of, Paraguay, Poland, Russian Federation, Spain, Tunisia, United Kingdom
Shire

Completed

Study of GA-GCB Enzyme Replacement Therapy in Type 1 Gaucher Disease Patients Previously Treated With Imiglucerase

Gaucher Disease

United States, Israel, United Kingdom, Poland, Spain
Shire

Approved for marketing

Treatment Protocol of Velaglucerase Alfa for Patients With Type 1 Gaucher Disease

Gaucher Disease, Type 1

United States
Roberto Léo da Silva

Completed

Preclinical Cardiomyopathy and Autonomic Function in Type 1 Diabetes

Diabetes Mellitus, Type 1 | Diabetic Cardiomyopathies | Autonomic Neuropathy, Diabetic

Brazil
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Pioglitazone Before Peginterferon and Ribavirin for Hepatitis C Infection in HIV/HCV-Coinfected Patients With Insulin Resistance

HIV-1 and Hepatitis C Co-Infection

United States
Trek Therapeutics, PBC

Completed

A Study of Faldaprevir, TD-6450 and Other Antivirals in Participants With Genotype 1b Hepatitis C Virus Infection

Chronic Hepatitis C | Hepatitis C Genotype 1 | Hepatitis C (HCV) | Hepatitis C Viral Infection

United States, New Zealand
Chromaderm, Inc.

Completed

Treatment for Symptomatic Peripheral Neuropathy in Patients With Diabetes

Diabetic Neuropathies | Diabetes Mellitus, Non-Insulin-Dependent | Diabetes Mellitus, Insulin-Dependent

Canada, United States, Croatia, Finland, India, Lithuania, Netherlands, United Kingdom
University Research Foundation for Lysosomal Storage...
University of Pittsburgh

Completed

Validating a New Severity Score System for Adults With Type 1 Gaucher Disease (GD1)

Gaucher Disease

United States
Shaare Zedek Medical Center

Completed

Comparison of BMD Measurement by DEXA to BeamMed Speed-of-Sound Measurement at Forearm in Patients With Gaucher Disease

Gaucher Disease Type 1

Israel
Edimer Pharmaceuticals

Completed

Phenotypic and Genetic Properties in Males at Risk for X-linked Hypohidrotic Ectodermal Dysplasia: Evaluation of an Early Diagnosis Technology and Tests to Assess Nutritional Status (ECP-013)

X-linked Hypohidrotic Ectodermal Dysplasia | Hypohidrotic Ectodermal Dysplasia

United States
Edimer Pharmaceuticals

Completed

Evaluation of Phenotypic and Genetic Properties in Male Subjects Affected By Hypohidrotic Ectodermal Dysplasia (ECP-012) (ECP-012)

X-linked Hypohidrotic Ectodermal Dysplasia | Hypohidrotic Ectodermal Dysplasia

Spain
Chinese PLA General Hospital

Completed

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD20

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
The Second Affiliated Hospital of Henan University...
Xuzhou Medical University; Xinqiao Hospital of Chongqing

Unknown

Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma (MatchCART)

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by CART19 (CART19)

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic... and other conditions

China
National Cancer Institute (NCI)

Active, not recruiting

Natural History Study of Patients With Neurofibromatosis Type I

Neurofibroma | Neurofibromatosis Type 1 | Malignant Peripheral Nerve Sheath Tumor | Optic Glioma | Plexiform Neurofibroma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Lenalidomide in Combination With Rituximab in Treating Participants With Stage III/IV Indolent Non-Hodgkin Lymphoma

Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage III Indolent Adult Non-Hodgkin Lymphoma | Ann Arbor Stage IV Grade 1 Follicular Lymphoma | Ann Arbor Stage IV Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Indolent Adult Non-Hodgkin... and other conditions

United States
Rush University Medical Center

Not yet recruiting

Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry (CNA-FWRD)

Vasovagal Syncope | AV Block-2Nd Degree-Type 1 | Sinus Pause
Massachusetts General Hospital
Johns Hopkins University

Recruiting

Dosing and Tolerability of Deoxycholic Acid Versus Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Neurofibromatosis 1

United States
University of Arkansas

Recruiting

Evaluating Mitochondrial Dysfunction in Patients With Neurofibromatosis Type 1

Neurofibromatosis 1

United States
Washington University School of Medicine
National Cancer Institute (NCI)

Not yet recruiting

A Behavioral Intervention to Promote Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia

Endometrial Hyperplasia | Grade 1 Endometrial Cancer

United States
Brown University
The Miriam Hospital; National Institute of General Medical Sciences (NIGMS)

Recruiting

Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection

Alcohol Drinking | HIV-1-infection

United States
Shandong Provincial Hospital

Recruiting

Pituitary Adenoma and Serum Lipid

Pituitary Adenoma 1, Acth-Secreting

China
University of Colorado, Denver

Recruiting

Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy

Non-Small Cell Lung Cancer | ALK Gene Mutation | EGFR Gene Mutation | BRAF V600E | Non-Small Cell Carcinoma of Lung, TNM Stage 4 | ROSE Cluster 1

United States
Children's Hospital Medical Center, Cincinnati

Active, not recruiting

Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1 (NF1NAC)

Neurofibromatosis 1

United States
The University of Texas Health Science Center,...
Texas Neurofibromatosis Foundation

Completed

Everolimus for Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis1 CRAD001CUS232T (DCLNF1)

Neurofibromatosis 1

United States
Shanghai Jiao Tong University School of Medicine

Completed

Neoadjuvant Toripalimab and Paclitaxel/Cisplatin on Pathological Response in Oral Squamous Cell Carcinoma Patients

Oral Cancer | Induction Chemotherapy | Programmed Cell Death 1 Inhibitor | Inductive Therapy

China
Endocrinology Research Centre, Moscow
Russian Science Foundation

Completed

Vitamin D Metabolism in Patients With Endocrine Disorders

Diabetes Mellitus, Type 1 | Primary Hyperparathyroidism | Acromegaly | Pituitary ACTH Hypersecretion

Russian Federation
University Hospital, Montpellier
Université Montpellier

Terminated

Transient Thermal Behavior and Diabetic Foot (PICOTE)

Diabetic Patients Type 1 and 2 | Podologic Grade From 0 to 3

France
Samsung Medical Center
AstraZeneca

Completed

BRCA 1/2 Mutation in Korean Patients With Epithelial Ovarian Cancer

To Investigate the Prevalence of BRCA 1/2 Mutation Among Ovarian Cancer
Juha Peltonen

Unknown

Analysis of Plasma for Diagnosis and Follow-up of Neurofibromatosis Type 1

Neurofibromatosis 1
National Cancer Institute (NCI)

Completed

Bortezomib in Treating Patients With Lymphoproliferative Disorders

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma

United States
Cancer Institute and Hospital, Chinese Academy...

Unknown

Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia

Childhood Acute Lymphoblastic Leukemia | B-cell Childhood Acute Lymphoblastic Leukemia | Philadelphia Chromosome, Ph^1^, Absent

China
Mayo Clinic

Completed

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1

Neurofibromatosis
GlaxoSmithKline

Completed

Prospective Epidemiological Study Of The Prevalence Of HLA-B*5701 In HIV-1 Infected Patients

HIV Infection | HIV-1 Infection | Infection, Human Immunodeficiency Virus I

Netherlands, Finland, Ireland, Portugal, Switzerland
CANbridge (Suzhou) Bio-pharma Co., Ltd.

Recruiting

Phase 1/2 Study of CAN103 in Subjects With Gaucher Disease

Gaucher Disease, Type 1 | Gaucher Disease, Type 3

China
Stanford University
Johns Hopkins University; University of California, San Francisco

Recruiting

Evaluating Genetic Modifiers of Cutaneous Neurofibromas in Adults With Neurofibromatosis Type 1

Neurofibromatosis 1

United States
Tianjin Medical University Cancer Institute and...

Not yet recruiting

An Exploratory Clinical Study of SHR6390 and SHR1020 in the Treatment of Esophageal Squamous Cell Carcinoma After Progression on PD-1 Antibody

Esophageal Squamous Cell Carcinoma | Progression to PD-1 Antibody

China
National Cancer Institute (NCI)

Recruiting

Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas

Neurofibromatosis 1

United States
Children's Hospital Medical Center, Cincinnati
United States Department of Defense

Recruiting

Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1 (DoDNAC)

Neurofibromatosis 1

United States
Tjhin Wiguna
Fakultas Kedokteran Universitas Indonesia

Not yet recruiting

Mental Health Assessment Among Community Member During the Covid-19 Pandemic in Indonesia (New)

Depression | Anxiety | Mental Health Wellness 1 | Behavior Problem | Mental Stress | Emotional Problem

Indonesia

Clinical Trials on LONGEVITY 1

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CROs in United States

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