Clinical Trials on Larynx Neoplasms

Total 107604 results

Danish Head and Neck Cancer Group

Completed

DAHANCA 28A: Phase I/II Study on Accelerated, Hyperfractionated Radiotherapy With Concomitant Cisplatin and Nimorazole

HNSCC,Larynx, Pharynx and Oral Cavity

Denmark
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer

Larynx | Oral Cavity | Lip | Pharynx

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Bristol-Myers Squibb

Completed

Nivolumab, Ipilimumab, and Radiation Therapy in Treating Patients With Stage III-IVB Head and Neck Cancer

Larynx | Lip, Oral Cavity and Pharynx

United States
Tata Medical Center

Completed

Dose Escalation Versus Standard in Laryngopharyngeal Cancers (INTELHOPE)

Malignant Neoplasm of Oropharynx Stage III | Malignant Neoplasm of Larynx Stage III | Malignant Neoplasm of Hypopharynx Stage III | Malignant Neoplasm of Oropharynx Stage IVa | Malignant Neoplasm of Oropharynx Stage IVb | Malignant Neoplasm of Larynx Stage IV | Malignant Neoplasm of Hypopharynx... and other conditions

India
University of Texas Southwestern Medical Center

Completed

CyberKnife Accelerated Hemilarynx Stereotactic Radiotherapy Study for Early-stage Glottic Larynx Cancer

Early-stage Glottic Larynx Cancer

United States
Tata Memorial Hospital
Ministry of Science and Technology, India

Terminated

Concurrent Chemoradiation Versus Surgery With Adjuvant Therapy in Advanced Laryngopharyngeal Cancers

Larynx Neoplasms

India
Latin American Cooperative Oncology Group
Merck Sharp & Dohme LLC

Active, not recruiting

Study of a Pembrolizumab-based Organ Preservation Strategy for Locally Advanced Larynx Cancers (SMART-KEY)

Squamous Cell Carcinoma of Larynx

Brazil
University of Leipzig
University of Kiel; University of Cologne; University of Jena; Technical University... and other collaborators

Not yet recruiting

European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] (ELOS)

Laryngeal Cancer | Squamous Cell Carcinoma of Head and Neck | Laryngeal Neoplasms | Squamous Cell Carcinoma of the Larynx | Hypopharyngeal Squamous Cell Carcinoma | Laryngeal Squamous Cell Carcinoma | Laryngectomy; Status | Squamous Cell Carcinoma of Larynx | Squamous Cell Carcinoma of the Larynx Stage... and other conditions
Hacettepe University

Completed

An Investigation of Biomarker Candidate Molecules in Laryngeal Carcinoma

Larynx Cancer | Larynx Carcinoma

Turkey
Michael Seltz Kristensen

Completed

Comparison Between a Standard Tube and the Ultra-thin Tritube for Intubation of the Trachea and for Maintaining Access to the Trachea After Anaesthesia, in Patients With an Expected Difficult Direct Laryngoscopy (Tritube)

Oral Neoplasm | Pharynx Cancer | Larynx Cancer

Denmark
Maria Sklodowska-Curie National Research Institute...
Medical Research Agency, Poland

Recruiting

Induction Treatment in SCC of the Head and Neck Region - Concomitant Chemotherapy and Low-dose Radiotherapy (iCHRTL)

Paranasal Sinus Carcinoma | Squamous Cell Carcinoma of Oral Cavity | Larynx Carcinoma | Pharynx Carcinoma

Poland
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Terminated

Cetuximab and Radiation Therapy in Treating Patients With Stage III-IV Head and Neck Cancer

Tongue Cancer | Stage III Squamous Cell Carcinoma of the Hypopharynx | Stage III Squamous Cell Carcinoma of the Larynx | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage III Verrucous Carcinoma of the Larynx | Stage IV Squamous Cell Carcinoma of the Hypopharynx | Stage IVA Squamous... and other conditions

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer

Human Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Hypopharynx | Stage III Squamous Cell Carcinoma of the Larynx | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage III Verrucous Carcinoma of the Larynx | Stage IV Squamous Cell Carcinoma of the Hypopharynx | Stage... and other conditions

United States
Radboud University Medical Center
Dutch Cancer Society

Completed

Randomized Trial of ARCON in Larynx Cancer

Larynx Carcinoma

Netherlands, United Kingdom
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Bilateral Elective Neck Dissection in Salvage Total Laryngectomy

Larynx | Larynx Cancer | Neck Cancer | Neck

Italy
Royal Brisbane and Women's Hospital

Completed

Breath Testing in Early and Late Larynx Cancer

Larynx Cancer

Australia
Groupe Oncologie Radiotherapie Tete et Cou
Tumor Study Group Head and Neck

Completed

Radiotherapy With Cisplatin Versus Radiotherapy With Cetuximab After Induction Chemotherapy for Larynx Preservation

Larynx Cancer | Hypopharynx Cancer

France
Mayo Clinic

Enrolling by invitation

Laryngeal Allograft Transplantation

Larynx | Larynx Disease | Laryngectomy | Larynx Stenosis | Larynx Fracture

United States
Groupe Oncologie Radiotherapie Tete et Cou
Sanofi

Completed

Induction CT by Cisplatin, 5FU With or Without Docetaxel in Patients With T3 and T4 Larynx and Hypopharynx Carcinoma

Larynx Cancer | Hypopharynx Cancer

France
National Cancer Institute, Egypt
Cairo University

Recruiting

Vocal Cord vs Whole Laryngeal Radiotherapy for T1aN0 Glottic Cancer (VC-Larynx)

Larynx Cancer Stage I | Glottic Carcinoma

Egypt
Thomas Jefferson University
Bristol-Myers Squibb

Active, not recruiting

Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck

Larynx | Squamous Cell Carcinoma | Lip | Oral Cavity Squamous Cell Carcinoma | Pharynx

United States
Olgun Elicin
University of Zurich; University Hospital, Geneva; University of Lausanne Hospitals and other collaborators

Recruiting

VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer (VoiceS)

Larynx Cancer | Glottis Tumor

Switzerland
Sidney Kimmel Cancer Center at Thomas Jefferson...

Active, not recruiting

Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery

Larynx | Oral Cavity | LIP | Pharynx

United States
Christian von Buchwald
Copenhagen University Hospital, Denmark; Department of Otorhinolaryngology,...

Recruiting

Cell-free Tumor DNA in Head and Neck Cancer Patients

Head and Neck Cancer | Head and Neck Neoplasms | Nasopharyngeal Carcinoma | Nasopharyngeal Cancer | Head and Neck Squamous Cell Carcinoma | Thyroid Neoplasms | Thyroid Carcinoma | Thyroid Cancer | Oral Cancer | Oropharynx Cancer | Salivary Gland Neoplasms | Oral Cavity Cancer | Oral Neoplasm | Larynx Cancer | Salivary... and other conditions

Denmark
Sidney Kimmel Cancer Center at Thomas Jefferson...
Bristol-Myers Squibb

Completed

Window of Opportunity Trial of Nivolumab and Tadalafil in Patients With Squamous Cell Carcinoma of the Head and Neck

Larynx | Lip, Oral Cavity and Pharynx

United States
MiMedx Group, Inc.

Terminated

Use of Human Dehydrated Amnion Chorion Allograft in Laryngectomy/Pharyngectomy

Pharynx Cancer | Larynx Cancer | Pharyngocutaneous Fistula

United States
ClinAssess
Sanofi; Merck Sharp & Dohme LLC

Completed

Docetaxel, Cisplatin (TP) + Radiation +/- Cetuximab in Larynx Carcinoma (CA) (DeLOS II)

Squamous Cell Carcinoma of the Hypopharynx | Larynx Carcinoma

Germany, Austria
University Hospital, Toulouse

Completed

Interest of Narrow Band Imaging in Detection of Upper Aerodigestive Cancers

Squamous Cell Carcinoma of Hypopharynx | Squamous Cell Carcinoma of Oropharynx | Squamous Cell Carcinoma of Larynx

France
Radboud University Medical Center
Dutch Cancer Society

Completed

Patient Selection for Hypoxia Modifying Treatments in Larynx Carcinomas

Larynx Cancer

Netherlands
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Randomized Trial to Assess the Impact of a Screening Program on Upper Aerodigestive Tract Cancer Mortality in a High Risk Population

Oral Cavity Cancer | Oesophageal Cancer | Pharynx Cancer | Larynx Cancer

France
American College of Radiology
RTOG Foundation

Not yet recruiting

Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Oropharynx
Erasmus Medical Center

Not yet recruiting

Fluorescence-guided Surgery in Laryngeal- and Hypopharyngeal Cancer: a Feasibility Trial (STELLAR)

Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Hypopharynx

Netherlands
Arbeitsgemeinschaft medikamentoese Tumortherapie

Completed

Induction Chemotherapy With TP+5-FU or TP+Cetuximab Followed by Radioimmuptherapy for Locally Advanced or Not Resectable SCCHNN (HNO-2)

Squamous Cell Carcinoma of the Hypopharynx Stage III | Squamous Cell Carcinoma of the Hypopharynx Stage IV | Squamous Cell Carcinoma of the Larynx Stage III | Squamous Cell Carcinoma of the Larynx Stage IV | Squamous Cell Carcinoma of the Oropharynx Stage III | Squamous Cell Carcinoma of the... and other conditions

Austria
National Cancer Institute (NCI)

Terminated

Gefitinib and Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III or Stage IV Head and Neck Cancer

Stage III Squamous Cell Carcinoma of the Hypopharynx | Stage III Squamous Cell Carcinoma of the Larynx | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IV Squamous Cell Carcinoma of the Hypopharynx | Stage IV Squamous... and other conditions

United States
AIO-Studien-gGmbH
Merck Sharp & Dohme LLC

Not yet recruiting

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome (HEAT)

Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of the Hypopharynx

Germany
University of Erlangen-Nürnberg Medical School

Recruiting

De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck (DIREKHT2)

Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of the Hypopharynx

Germany
National Cancer Institute (NCI)

Completed

Erlotinib, Docetaxel, and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer

Tongue Cancer | Stage III Squamous Cell Carcinoma of the Hypopharynx | Stage III Squamous Cell Carcinoma of the Larynx | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Nasopharynx | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage... and other conditions

United States
Kyunghee Burkitt, DO, PhD

Not yet recruiting

Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC (HPV)

Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | HPV-Related Squamous Cell Carcinoma | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of the Hypopharynx

United States
University of Florida

Withdrawn

Radiotherapy Dose Escalation in Locally Advanced Squamous Cell Carcinoma of the Larynx or Hypopharynx

Advanced Squamous Cell Carcinoma

United States
Wake Forest University Health Sciences

Terminated

Esophagoscopy in Evaluating Treatment in Patients With Stage I-IV Head and Neck Cancer Who Are Undergoing Radiation Therapy and/or Chemotherapy

Stage I Adenoid Cystic Carcinoma of the Oral Cavity | Stage I Mucoepidermoid Carcinoma of the Oral Cavity | Stage I Squamous Cell Carcinoma of the Hypopharynx | Stage I Squamous Cell Carcinoma of the Larynx | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Verrucous Carcinoma... and other conditions

United States
Susanne Arnold

Completed

A Study of Chemo +/- Low-dose Radiation as Induction Therapy in SCCHN

Head and Neck Cancer | Larynx

United States
Johnny Kao

Completed

Erlotinib, Celecoxib and Reirradiation for Recurrent Head and Neck Cancer

Paranasal Sinus Neoplasms | Cancer of the Head | Cancer of the Neck | Cancer of the Pharynx | Cancer of the Larynx

United States
University Hospital, Ghent

Completed

Comparison of Adaptive Dose Painting by Numbers With Standard Radiotherapy for Head and Neck Cancer. (C-ART-2)

Primary Non-operated Squamous Cell Carcinoma of Oral Cavity | Primary Non-operated Squamous Cell Carcinoma of Oropharynx | Primary Non-operated Squamous Cell Carcinoma of Hypopharynx | Primary Non-operated Squamous Cell Carcinoma of Larynx

Belgium
National Cancer Institute (NCI)

Completed

Depsipeptide in Unresectable Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Stage IV Squamous Cell Carcinoma of the Hypopharynx | Stage IV Squamous Cell Carcinoma of the Larynx | Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IV Squamous Cell Carcinoma of the Oropharynx

United States
University Hospital, Ghent

Completed

Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck

Primary Non-operated Squamous Cell Carcinoma of Oral Cavity | Primary Non-operated Squamous Cell Carcinoma of Oropharynx | Primary Non-operated Squamous Cell Carcinoma of Hypopharynx | Primary Non-operated Squamous Cell Carcinoma of Larynx

Belgium
University of Texas Southwestern Medical Center

Terminated

HYpofractionateD RadioAblative (HYDRA) Treatment of Advanced Laryngeal Cancer (HYDRA)

Squamous Cell Carcinoma of the Larynx

United States
Johnny Kao

Completed

Fluorouracil, Hydroxyurea, Cetuximab and Twice-daily Intensity Radiation Therapy for Advanced Head and Neck Cancer

Head and Neck Cancer | Nose Neoplasms | Paranasal Sinus Neoplasms | Cancer of the Pharynx | Cancer of the Larynx | Cancer of the Oral Cavity

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck

Tongue Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Verrucous Carcinoma of the Larynx | Recurrent Verrucous Carcinoma of the Oral Cavity | Recurrent Adenoid... and other conditions

United States
University Hospital, Caen
Centre Francois Baclesse

Completed

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Could Decrease the Incidence of Oxygen Desaturation During Suspension Laryngoscopy: a Randomized Controlled Trial (Optilaryngo) (optilaryngo)

Apnea | Anesthesia | Desaturation of Blood | Apnea, Postanesthetic | Larynx Disease | Pharynx; Anomaly

France
University of Chicago

Completed

Docetaxel Based Chemotherapy Plus or Minus Induction Chemotherapy to Decrease Events in Head and Neck Cancer (DeCIDE) (DeCIDE)

Paranasal Sinus Neoplasms | Cancer of the Pharynx | Cancer of the Larynx | Cancer of the Nasal Cavity | Cancer of the Oral Cavity

United States, Spain, France, Croatia, Russian Federation

Clinical Trials on Larynx Neoplasms

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