Clinical Trials on Laser in Situ Keratomileusis

Total 1206 results

Massachusetts General Hospital
National Cancer Institute (NCI)

Completed

Proton Beam Radiation Therapy in Treating Young Patients Who Have Undergone Biopsy or Surgery for Medulloblastoma or Pineoblastoma

Brain and Central Nervous System Tumors | Long-term Effects Secondary to Cancer Therapy in Children

United States
Antiva Biosciences

Terminated

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

HIV Infection | Anal Cancer | Human Papilloma Virus Infection | HSIL, High-Grade Squamous Intraepithelial Lesions | Anus Neoplasm

United States, Australia
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

HIV Infection | Anal Cancer | Anus Neoplasms | Human Papilloma Virus Infection | HSIL, High-Grade Squamous Intraepithelial Lesions

United States, Australia
Catharina Ziekenhuis Eindhoven
ZonMw: The Netherlands Organisation for Health Research and Development; Stichting... and other collaborators

Recruiting

Predicting Response In Cervical Intraepithelial Neoplasia to Topical Imiquimod Treatment (PRedICT-TOPIC)

Cervical Intraepithelial Neoplasia | CIN 2/3 | Cervical Intraepithelial Neoplasia Grade 2/3 | Cervical High Grade Squamous Intraepithelial Lesion

Netherlands
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Completed

ALA-PDT in Patients With CIN2 in p16-positivity and High-risk HPV Infection

Papillomavirus Infections | Cervical Intraepithelial Neoplasia Grade 2 | p16 Protein

China
Inovio Pharmaceuticals

Completed

Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)

Human Papillomavirus (HPV) | Vulvar Dysplasia | Vulvar Intraepithelial Neoplasia (VIN) | Vulvar High Grade Squamous Intraepithelial Lesion (HSIL) | VIN2 | VIN3 | Pre-cancerous Lesions of the Vulva

United States
University Hospital, Tours

Completed

Effect of Salpingectomy During Conservative Hysterectomy (SALPINGOVA)

Genital Diseases, Female | Uterine Prolapse | Dysfunctional Uterine Bleeding | Cervical Dysplasia | Hysterotomy; Affecting Fetus | Leiomyomata Uteri | Adenomyosis, Endometriosis

France
University of Washington
National Cancer Institute (NCI)

Completed

Home-Based or Clinic-Based Human Papillomavirus (HPV) Screening

Cervical Carcinoma | Human Papillomavirus Infection | Health Status Unknown | Cervical Intraepithelial Neoplasia Grade 2/3 | Stage 0 Cervical Cancer | Atypical Squamous Cell of Undetermined Significance | Low Grade Cervical Squamous Intraepithelial Neoplasia

United States
RinuaGene Biotechnology Co., Ltd.

Not yet recruiting

A Study in Subjects With Human Papillomavirus 16 or 18 Associated Cervical Intraepithelial Neoplasia Grade 2 or 3

Cervical Intraepithelial Neoplasia Grade 2/3 | Human Papillomavirus Associated Intraepithelial Neoplasia | Human Papillomavirus Type 16 Infection | Human Papillomavirus Type 18 Infection
Centre Leon Berard

Recruiting

Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Transplantation (EVAADE)

Myelodysplastic Syndromes | Severe Combined Immunodeficiency | Acute Leukemia | Haematological Malignancy | Hemoglobinopathy in Children | Bone Marrow Aplasia

France
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Cemiplimab for the Treatment of Untreated Brain Metastases From PD-L1 >= 50% Non-Small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain

United States
University of Southern California
National Cancer Institute (NCI); Auransa, Inc.

Recruiting

AU409 for the Treatment of Advanced Primary Liver Cancers or Solid Tumor With Liver Metastatic Disease

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Advanced Hepatocellular Carcinoma | Metastatic Malignant Neoplasm in the Liver | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
SWOG Cancer Research Network
National Cancer Institute (NCI); Gilead Sciences

Recruiting

Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Invasive Breast Carcinoma | Metastatic Malignant Neoplasm in the Brain | Metastatic HER2 Negative Breast Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

Metastatic Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastatic Melanoma in the Brain

Recurrent Glioblastoma | Metastatic Melanoma | Recurrent Malignant Glioma | Metastatic Malignant Neoplasm in the Brain | Recurrent Brain Neoplasm

United States
Centre Leon Berard

Withdrawn

A Study to Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Allografts (EVAADE)

Myelodysplastic Syndromes | Severe Combined Immunodeficiency | Acute Leukemia | Haematological Malignancy | Hemoglobinopathy in Children | Bone Marrow Aplasia

France
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases

Recurrent Breast Carcinoma | Metastatic Triple-Negative Breast Carcinoma | Metastatic Malignant Neoplasm in the Brain | Stage IV Breast Cancer AJCC v6 and v7 | Metastatic Breast Carcinoma | Metastatic BRCA Hereditary Breast Carcinoma

United States, Puerto Rico
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Antiandrogen Therapy With or Without Axitinib Before Surgery in Treating Patients With Previously Untreated Prostate Cancer With Known or Suspected Lymph Node Metastasis

Metastatic Malignant Neoplasm in Lymph Node | Prostate Ductal Adenocarcinoma | Stage III Prostate Adenocarcinoma AJCC v7 | Stage IV Prostate Adenocarcinoma AJCC v7

United States
Mayo Clinic
National Cancer Institute (NCI)

Withdrawn

Carbon Dioxide Fractional Laser in Treating Participants With Stage 0-III Hormone Receptor-Positive Breast Cancer With Vulvovaginal Atrophy

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumor | Metastatic Malignant Neoplasm in the Liver | Stage I Pancreatic Neuroendocrine Tumor AJCC v8 | Stage II Pancreatic Neuroendocrine Tumor AJCC v8 | Stage III Pancreatic Neuroendocrine Tumor AJCC v8

United States
University of Southern California
National Cancer Institute (NCI)

Recruiting

7T MRI Scan for the Early Detection of Melanoma Brain Metastases

Metastatic Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain

United States
National Cancer Institute (NCI)
Radiation Therapy Oncology Group

Terminated

Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | Metastatic Malignant Neoplasm in the Brain | Stage IV Non-Small Cell Lung Cancer AJCC v7

United States, Canada
M.D. Anderson Cancer Center

Recruiting

Early Assessment of Ovarian Cancer Aggressiveness by Metabolic Imaging

Ovarian Cancer

United States
Indonesia University
Vygon GmbH & Co. KG

Completed

Efficacy of Sternum Guard in Post Cardiac Surgery Patient

Coronary Artery Disease | Surgical Site Infection | Postoperative Hemorrhage | Valvular Heart Disease | Congenital Heart Disease in Adolescence | Post Operative Wound Infection

Indonesia
Children's Cancer and Leukaemia Group

Unknown

Quality of Life in Patients Who Have Undergone Previous Treatment for Primitive Neuroectodermal Tumors

Brain and Central Nervous System Tumors | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United Kingdom, Ireland
Gesellschaft fur Padiatrische Onkologie und Hamatologie...

Completed

Observation of Young Patients Who Are Undergoing Surgery for Craniopharyngioma

Brain and Central Nervous System Tumors | Perioperative/Postoperative Complications | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment | Weight Changes

Switzerland, Germany, Austria, Sweden
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Stage IIIC Cutaneous Melanoma AJCC v7 | Unresectable Melanoma | Metastatic Malignant Neoplasm in the Brain | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases

Metastatic Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain

United States
Roswell Park Cancer Institute

Completed

Cisplatin in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer or Lung Metastasis

Stage IIIB Non-Small Cell Lung Cancer | Stage IV Non-Small Cell Lung Cancer | Stage IV Adult Soft Tissue Sarcoma | Metastatic Malignant Neoplasm in the Lung

United States
Istanbul University - Cerrahpasa (IUC)

Unknown

OPHTHALMOLOGIC EVALUATION OF RADIATION-RELATED OPTIC NEUROPATHY FOLLOWING IMAGE GUIDED INTENSITY-MODULATED RADIATION THERAPY (IMRT) FOR NASOPHARYNGEAL CARCİNOMA (ORONIN)

The Aim of Our Study is to Prospectively Evaluate the Optic Neuropathy in Nasopharynx Cancer Patients

Turkey
Louisiana State University Health Sciences Center...
Merck Sharp & Dohme LLC

Recruiting

Immunogenicity of Gardasil-9 HPV Vaccine in People Living With HIV (AGO-Gard)

Cervical Intraepithelial Neoplasia | Human Immunodeficiency Virus | Anal Intraepithelial Neoplasia | Papillomavirus Infection | Papillomavirus Vaccines | Serology | Oral Cavity Infection

United States
University of Washington
National Cancer Institute (NCI)

Recruiting

Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Soft Tissues | Recurrent Bladder Carcinoma | Recurrent Prostate Carcinoma | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Metastatic Renal Pelvis and Ureter Urothelial Carcinoma | Localized... and other conditions

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

Metastatic Melanoma | Metastatic Cutaneous Melanoma | Acral Lentiginous Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Metastatic Mucosal Melanoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies

Malignant Solid Neoplasm | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate... and other conditions

United States
Blueprint Medicines Corporation

Active, not recruiting

(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | EGF-R Positive Non-Small Cell Lung... and other conditions

United States, Canada, Taiwan, Korea, Republic of, Singapore, Japan, United Kingdom, France, Netherlands, Spain
Charite University, Berlin, Germany

Unknown

Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis

Colorectal Cancer | Crohn Disease | Ulcerative Colitis | Familial Adenomatous Polyposis | Crohn Colitis | Ulcerative Colitis Chronic | Ulcerative Colitis in Remission | Ileal Pouch

Germany
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Esophageal Cytology With FISH in Detecting Esophageal Cancer

Esophagitis | Weight Loss | Gastroesophageal Reflux Disease | Dysphagia | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Dysplasia | High Grade Dysplasia in Barrett Esophagus

United States
Beijing Suncadia Pharmaceuticals Co., Ltd

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of SHR-2004 Injection in Preventing Postoperative Venous Thromboembolism in Patients Undergoing Ovarian Cancer Surgery

Preventing Postoperative Venous Thromboembolism in Patients Undergoing Ovarian Cancer Surgery
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Recruiting

Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases

Glioma | Astrocytoma | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Oligodendroglioma | Recurrent Glioma | Invasive Breast Carcinoma | Breast Carcinoma Metastatic in the Brain

United States
Southwest Oncology Group
Patient-Centered Outcomes Research Institute; National Cancer Institute (NCI)

Completed

S1415CD, Trial Assessing CSF Prescribing Effectiveness and Risk (TrACER) (TrACER)

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Febrile Neutropenia | Stage 0 Breast Cancer | Stage IV Non-Small Cell Lung Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast... and other conditions

United States, Puerto Rico
AstraZeneca

Recruiting

Assessment of Safety of Olaparib in Chinese Patients With Ovarian Cancer in the Real-World Setting

Using NCID Database to Assess the Safety of Olaparib in Chinese Patients With Ovarian Cancer by Examining the Incidence, Seriousness, and Severity of All AE

China
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

Metastatic Lung Non-Small Cell Carcinoma | Anaplastic Astrocytoma, IDH-Wildtype | Glioblastoma, IDH-Wildtype | Metastatic Malignant Neoplasm in the Central Nervous System

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

Brain and Central Nervous System Tumors | Long-term Effects Secondary to Cancer Therapy in Children | Drug/Agent Toxicity by Tissue/Organ | Bone Marrow Suppression

United States
University College, London
University College London Hospitals

Completed

Oral Epithelial Dysplasia Informational Needs Questionnaire (ODIN-Q)

Quality of Life | Precancerous Conditions | Patient Engagement | Patient Participation | Oral Disease | Patient Satisfaction | Health Behavior | Precancerous Lesions | Oral Leukoplakia | Dental Diseases | Oral Lichen Planus | Dysplasia | Patient Preference | Information Seeking Behavior | Oral Epithelial Dysplasia | Oral... and other conditions

United Kingdom
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, San Francisco; University... and other collaborators

Active, not recruiting

Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions (ANCHOR)

HIV Infection | Anal Cancer | Human Papilloma Virus Infection | High-grade Squamous Intraepithelial Lesion

United States, Puerto Rico
Inovio Pharmaceuticals

Completed

VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2

Anal Neoplasm

United States, Canada
Frantz Viral Therapeutics, LLC
Anal Dysplasia Clinic MidWest; Laser Surgery Care, LLC

Recruiting

Artesunate Ointment for the Treatment of Anal HSIL in HIV-negative Participants (ART-AIN IIB-2)

Anal High-grade Squamous Intraepithelial Lesion | Anal HSIL | Anal HPV Infection

United States
Juna d.o.o.

Unknown

Safety and Efficacy of Laser Therapy in Gynaecology

Cervical Intraepithelial Neoplasia | Hidradenitis Suppurativa | Lichen Sclerosus | Herpes Genitalis | Genital Wart | Labial Reduction Surgery | Episiotomy Scar | Bartholin Cyst

Slovenia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

Sarcoma | Metastatic Melanoma | Thyroid Gland Carcinoma | Metastatic Malignant Neoplasm of Unknown Primary | Spinal Cord Compression | Stage IV Breast Cancer AJCC v6 and v7 | Malignant Digestive System Neoplasm | Metastatic Malignant Neoplasm in the Spine | Metastatic Kidney Carcinoma | Metastatic Head... and other conditions

United States
Sumithira Vasu

Completed

Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia With t(8... and other conditions

United States

Clinical Trials on Laser in Situ Keratomileusis

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kuwait

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations