Clinical Trials on Laurence-Moon Syndrome in United Kingdom

Total 17289 results

Rhythm Pharmaceuticals, Inc.

Completed

Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Patients With Specific Gene Defects in the MC4R Pathway

Bardet-Biedl Syndrome | POMC Deficiency

Netherlands, United States, Germany, Canada, Puerto Rico, United Kingdom
Marshfield Clinic Research Foundation

Recruiting

Clinical Registry Investigating Bardet-Biedl Syndrome (CRIBBS)

Bardet-Biedl Syndrome

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in Pediatric Patients With Rare Genetic Diseases of Obesity

Bardet-Biedl Syndrome | POMC Deficiency Obesity | PCSK1 Deficiency Obesity | LEPR Deficiency Obesity

United States, Australia, Spain, United Kingdom
National Human Genome Research Institute (NHGRI)

Terminated

Genetics and Clinical Characteristics of Bardet-Biedl Syndrome

Bardet-Biedl Syndrome

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

Bardet Biedl Syndrome (BBS) | Alström Syndrome (AS)

United States, United Kingdom, France, Canada, Puerto Rico, Spain
Myota GmbH

Active, not recruiting

PRebiotic Intervention for Metabolic and MEntal Health (PRIME) (PRIME)

Stress | Metabolic Syndrome | Anxiety | Mood

United Kingdom
St. Bartholomew's Hospital

Unknown

Erythropoietin (EPO) and Granulocyte-Colony Stimulating Factor (G-CSF) for Low-Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes

United Kingdom
Brighton and Sussex University Hospitals NHS Trust
Medtronic Vascular

Completed

Revascularisation or Medical Therapy in Elderly Patients With Acute Anginal Syndromes (RINCAL)

Acute Coronary Syndromes

United Kingdom
University College, London
King's College London; King's College Hospital NHS Trust; University of Oxford; Great Ormond Street Hospital for Children NHS Foundation Trust

Recruiting

Children's Adaptive Deep Brain Stimulation for Epilepsy Trial (CADET): Pilot (CADET Pilot)

Epilepsy | Lennox-Gastaut Syndrome, Intractable

United Kingdom
University of Portsmouth
Portsmouth Hospitals NHS Trust

Not yet recruiting

The Effects of Prolonged Head-Down Tilt Lithotomy Position on Lower Limb Haemodynamics (HELP)

Compartment Syndrome Nontraumatic Lower Extremity

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Unknown

Cubital Tunnel Syndrome and Diffusion MRI: A Proof of Concept Study

Cubital Tunnel Syndrome

United Kingdom
Oxford University Hospitals NHS Trust

Unknown

Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants

Myelodysplastic Syndromes | Leukemia

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Not yet recruiting

Low-Dose IL-2 For The Reduction Of Vascular Inflammation In ACS -Clinical Outcomes & Follow-up Study (IVORY-FINALE)

Acute Coronary Syndromes

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Active, not recruiting

Low-dose Interleukin-2 for the Reduction of Vascular Inflammation in Acute Coronary Syndromes - IVORY (IVORY)

Acute Coronary Syndromes

United Kingdom
King's College Hospital NHS Trust

Completed

The Efficacy and Safety of Lenalidomide Monotherapy in Red Blood Cell Transfusion Dependent Subjects With Myelodysplastic Syndrome (MDS) Associated With Del (5q) Abnormality

Myelodysplastic Syndromes

United Kingdom
Imperial College London
The Drummond Foundation (RAMC charity)

Recruiting

Chemical Analysis of Limb Microfluidics (CALM)

Compartment Syndrome of Leg | Limb Ischemia

United Kingdom
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
Allergan

Terminated

Clinical Study to Evaluate Tear Characteristics Following Acute TrueTear™ Use

Dry Eye Syndromes

United Kingdom
Barts & The London NHS Trust
Cancer Research UK; Amgen

Unknown

Comparison Study of Standard Care Against Combination of Growth Factors Agents for Low-risk Myelodysplastic Syndromes (REGIME)

Myelodysplastic Syndrome

United Kingdom
Takeda

Recruiting

A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

Dravet Syndrome (DS) | Lennox-Gastaut Syndrome (LGS)

United Kingdom, Denmark
University Hospital Birmingham NHS Foundation Trust

Completed

The Application of Near Infrared Spectroscopy (NIRS) in the Detection of Lower Limb Compartment Syndrome

Compartment Syndrome

United Kingdom
University of the West of England
Royal United Hospital Bath NHS Trust

Completed

Self Soft Tissue Therapy for Fibromyalgia Syndrome

Fibromyalgia Syndrome

United Kingdom
King's College Hospital NHS Trust

Terminated

Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin (FB-ATG)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
UCB BIOSCIENCES, Inc.

Recruiting

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome (ORCHID)

Dravet Syndrome

United States, United Kingdom
University College, London
Barts & The London NHS Trust

Unknown

Coronary Mortality in South Asians: Aetiologic and Prognostic Effects (CALIBER)

Acute Coronary Syndromes

United Kingdom
Institute of Cancer Research, United Kingdom
Cancer Research UK; National Institute for Health Research, United Kingdom

Completed

Magnetic Resonance Imaging Screening in Li Fraumeni Syndrome (SIGNIFY)

Li-Fraumeni Syndrome

United Kingdom
John Carroll University
University Hospital Southampton NHS Foundation Trust

Active, not recruiting

Development and Validation of an Online Neurobehavioral Evaluation Tool for PTEN Patients

PTEN Hamartoma Tumor Syndrome

United States, United Kingdom
University College, London

Completed

SS-INQ Information Needs Questionnaire in Sjögren's Syndrome (SS-INQ)

Sjögren's Syndrome

United Kingdom
Imperial College London

Withdrawn

Liraglutide on Decreasing Parenteral Support in Short Bowel Patients (SLIPS) (SLIPS)

Short Bowel Syndrome

United Kingdom
Allergan

Completed

Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye Symptoms

Dry Eye Syndromes

United Kingdom
Lisa M. Guay-Woodford
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

UAB HRFD Core Center: Core A: The Hepato/Renal Fibrocystic Diseases Translational Resource

Nephronophthisis | Joubert Syndrome | Bardet Biedl Syndrome | Autosomal Recessive Polycystic Kidney Disease | Congenital Hepatic Fibrosis | Hepato/Renal Fibrocystic Disease | Meckel-Gruber Syndrome | Caroli Syndrome | Oro-Facial-Digital Syndrome Type I | Glomerulocystic Kidney Disease

United States
Aston University

Not yet recruiting

Photobiomodulation With REd vs BluE Light (REBEL)

Dry Eye Syndromes | Meibomian Gland Dysfunction | Blepharitis

United Kingdom
Millennium Pharmaceuticals, Inc.

Completed

Study of TAK-935 as an Adjunctive Therapy in Adult Participants With Complex Regional Pain Syndrome (CRPS)

Complex Regional Pain Syndrome

United Kingdom
University of Suffolk

Recruiting

The 5Ad Diet for Functional Bowel Disorders

Irritable Bowel Syndrome | Food Intolerance | Functional Bowel Disorder | Food Intolerance Syndromes

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Gastrectomy, Eating Behaviour and GLP-1

Gastric Cancer | Dumping Syndrome

United Kingdom
London North West Healthcare NHS Trust

Not yet recruiting

PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome (PSYLIVED)

Lynch Syndrome | Polyposis Syndrome, Hereditary Mixed, 1 | Polyposis Syndrome, Hereditary Mixed, 2

United Kingdom
Medical Research Council

Completed

Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myeloid Leukemia

Myelodysplastic Syndromes | Leukemia

United Kingdom
St Mark's Hospital Foundation

Completed

Citrulline: A Plasmatic Marker to Assess and Monitor Small Bowel Crohn's Disease Patients

Celiac Disease | Malabsorption Syndromes | Crohn's Disease | Short Bowel Syndrome

United Kingdom
University of Aberdeen
NHS Grampian; Softcell Medical Ltd

Not yet recruiting

Real-time Soft Tissue Assessment Using a Technologically Advanced pH Monitoring System (SoftpH)

Acute Compartment Syndrome

United Kingdom
Genzyme, a Sanofi Company

Terminated

Rabbit Anti-thymocyte Globulin in the Treatment of Patients With Low to Intermediate-1 Risk Myelodysplastic Syndrome (RISE)

Myelodysplastic Syndrome (MDS)

Germany, United Kingdom, France, Netherlands
Beneo-Institute
University of Reading

Completed

Effects of Prebiotics on Intestinal Colonization and Mood in a University Cohort

Mood

United Kingdom
Keele University
Arthritis Research UK

Completed

Injection Versus Splinting in Carpal Tunnel Syndrome (INSTinCTS)

Carpal Tunnel Syndrome (CTS)

United Kingdom
Kirby Institute

Completed

Pharmacokinetics of Lopinavir/Ritonavir at Three Different Doses. (ENCORE3)

Acquired Immunodeficiency Syndrome

United Kingdom
Allergan

Completed

A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry Eye

Dry Eye Syndromes | Keratoconjunctivitis Sicca

France, United Kingdom
Optometric Technology Group Ltd
Allergan

Completed

Efficacy Study of a New Eyedrop on Silicone Hydrogel Contact Lens Wearers With Dry Eye Complaints

Contact Lens Related Dry Eye Syndrome

United Kingdom
Jing Advanced Massage Training
Medway NHS Foundation Trust

Completed

Clinical Massage Therapy as a Treatment for Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

United Kingdom
East Kent Hospitals University NHS Foundation Trust

Completed

Ultrasound Therapy for Carpal Tunnel Syndrome (CTS) (CTS)

Carpal Tunnel Syndrome

United Kingdom
King's College London
King's College Hospital NHS Trust

Unknown

Use of Decitabine in Myelodysplastic Syndrome (MDS) Following Azacitidine (AZA) Failure (DEC-MDS)

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome

United Kingdom
King's College Hospital NHS Trust

Unknown

Prophylactic DLI for the Prevention of Relapse Post HSCT in Patients With High Risk Myeloid Malignancy (PRO-DLI)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
Royal Marsden NHS Foundation Trust

Recruiting

Inherited Cancer Early Diagnosis (ICED) Study (ICED)

Lynch Syndrome | Familial Adenomatous Polyposis | Hereditary Diffuse Gastric Cancer | Peutz-Jeghers Syndrome | Cowden Syndrome | Li Fraumeni Syndrome | MutYH-associated Polyposis | SMAD4 Gene Mutation

United Kingdom

Clinical Trials on Laurence-Moon Syndrome in United Kingdom

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