Clinical Trials on Left Atrial Dilatation in United Kingdom

Total 5146 results

Cytokinetics

Completed

Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)

Heart Failure

United States, Canada, Germany, Italy, Netherlands, Belgium, France, Czechia, Australia, Russian Federation, Hungary, Poland, Bulgaria, Slovakia, United Kingdom, Finland, Greece, Lithuania, Norway
Utrecht Institute for Pharmaceutical Sciences
Uppsala University; Erasmus Medical Center; Newcastle University; University of... and other collaborators

Completed

EUropean Pharmacogenetics of AntiCoagulant Therapy - Warfarin (EU-PACT)

Atrial Fibrillation | Venous Thromboembolism

Sweden, United Kingdom
Hull University Teaching Hospitals NHS Trust
University of Hull

Active, not recruiting

Shockwave Therapy in Lower Limb Intermittent Calf Claudication (SLICC)

Peripheral Vascular Disease

United Kingdom
GlaxoSmithKline

Completed

Positron Emission Tomography (PET) Study to Evaluate Biodistribution of [11C]-GSK2256098 in Healthy Subjects and Idiopathic Pulmonary Arterial Hypertension (PAH) Patients

Hypertension, Pulmonary

United Kingdom
Atrial Fibrillation Network

Not yet recruiting

Early Atrial Fibrillation Ablation for Stroke Prevention in Patients With High Comorbidity Burden (EASThigh-AFNET 11)

Atrial Fibrillation

Germany, Australia, Canada, Netherlands, United Kingdom
Imperial College London

Completed

The Study of Apelin-APJ System on Pulmonary Hypertension Patients and Healthy Subjects (EXAP)

Idiopathic Pulmonary Arterial Hypertension

United Kingdom
University College, London
London School of Hygiene and Tropical Medicine; St Bartholomews and The Royal...

Unknown

A CALIBER Study: Risk Factors for Stroke, Heart Failure, and Myocardial Infarction in Atrial Fibrillation

Myocardial Infarction | Heart Failure | Stroke | Atrial Fibrillation

United Kingdom
Glasgow Caledonian University
King's College London; St George's, University of London; University of Glasgow; NHS Lanarkshire

Recruiting

Motivating Physical Activity With Behavioural interVention and Electrical Stimulation Remotely in Intermittent Claudication (MAvERIC)

Intermittent Claudication | Peripheral Artery Disease

United Kingdom
AtriCure, Inc.

Recruiting

CONVERGE Post-Approval Study (PAS)

Chronic Atrial Fibrillation

United States, United Kingdom
Abbott Medical Devices

Completed

MOMENTUM 3 Pivotal Cohort Extended Follow-up PAS

Advanced Refractory Left Ventricular Heart Failure

United States
Imperial College London

Terminated

A Human In Vivo Feeding Study Of The Blood Monocyte Response To Dietary Lipid Intake (Lipophage14)

Atherosclerosis

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; British Heart Foundation

Recruiting

Atrial CMR in Patients With CVA of Unknown Source and no Known AF (CARM-AF)

Atrial Fibrillation | Stroke, Ischemic

United Kingdom
Occlutech International AB

Completed

Prospective, Non-randomized, Safety and Efficacy Study of a New Occluder Design for Minimally Invasive Closure of the Left Atrial Appendage (LAA) in Patients With Atrial Fibrillation (OLAAC)

Atrial Fibrillation

Germany, United Kingdom
Acutus Medical

Completed

Utilizing Novel Dipole Density Capabilities to Objectively Visualize the Etiology of Rhythms in Atrial Fibrillation (UNCOVER-AF)

Persistent Atrial Fibrillation

United Kingdom, Germany, Netherlands, Canada, Czechia, Italy
Imperial College London

Completed

Neuromuscular Electrical Stimulation (NMES) in Patients With Intermittent Claudication (IC)

Intermittent Claudication | Peripheral Vascular Disease

United Kingdom
Bial - Portela C S.A.
Covance

Completed

Effect of BIA 5 1058 on Cardiac Repolarization

Heart Failure | Cardiovascular Disease | Pulmonary Arterial Hypertension

United Kingdom
Hansen Medical

Terminated

Use of the Hansen Medical System in Patients With Paroxysmal Atrial Fibrillation

Paroxysmal Atrial Fibrillation

United States, Denmark, Czechia, Spain, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield Hallam University; University of York; University of Stirling

Completed

Structured EDucation for Rehabilitation in Intermittent Claudication (SEDRIC)

Peripheral Arterial Disease

United Kingdom
University Hospital Birmingham
University of Birmingham

Recruiting

Outcome of Overweight AF Patients Following Ablation With a Potential Weight Loss Medication ( GOAL-AF ) (GOAL-AF)

Recurrence | Atrial Fibrillation | Overweight and Obesity | Liraglutide

United Kingdom
Eisai Inc.

Completed

A Study to Investigate the Potential Pharmacokinetic Interaction of Perampanel With Oral Contraceptives in Healthy Female Subjects

Partial Onset Epilepsy

United Kingdom
Eisai Inc.

Completed

A Study to Demonstrate Bioequivalence Between 6 x 2 mg Tablets of Perampanel and a Single 12 mg Tablet of Perampanel in Healthy Subjects

Partial Onset Epilepsy

United Kingdom
University of Oxford
Merck KGaA, Darmstadt, Germany

Unknown

Oxford Niaspan Study: Effects of Niaspan on Atherosclerosis and Endothelial Function

Atherosclerosis

United Kingdom
Swansea University
Bristol-Myers Squibb; Pfizer

Completed

Evaluating Quality of Life of AF Patients Following a Bleed (EQUAL-AF)

Atrial Fibrillation

United Kingdom
University of Oxford

Recruiting

LOSE-AF: Can Weight Loss Help Patients With Atrial Fibrillation? (LOSE-AF)

Atrial Fibrillation | Overweight and Obesity

United Kingdom
University of Edinburgh
Encysive Pharmaceuticals

Completed

Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)

Pulmonary Arterial Hypertension | Vasodilation | Vasoconstriction

United Kingdom
University of Oxford

Completed

A Short CONSORT Checklist for Peer Reviewers to Improve the Reporting of Randomised Controlled Trials Published (CONSORT-PR)

Adequate Reporting in Randomized Controlled Trials

United States, United Kingdom
York Teaching Hospitals NHS Foundation Trust
University of York; University of Salford; York St John University

Completed

York Study of Unloading Shoes for Vascular Intermittent Claudication (YORVIC)

Peripheral Arterial Disease | Intermittent Claudication

United Kingdom
Cardiovascular Innovation and Research Institute
Valley View Hospital

Recruiting

Cardiovascular Innovation & Research Institute 's NEXUS Registry, the Whole is Greater Than the Parts.

Coronary Artery Disease | Atrial Fibrillation (AF)

United States
University of Leicester
University Hospitals, Leicester

Not yet recruiting

Cognitive Impairment and Cerebral Haemodynamics in Individuals With Symptomatic Peripheral Arterial Disease (CInCH PAD)

Peripheral Arterial Disease | Cognitive Impairment

United Kingdom
Bial - Portela C S.A.

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BIA 5-1058

Pulmonary Arterial Hypertension | Cardiovascular Disease+Pulmonary Disease

United Kingdom
St George's, University of London
University of Copenhagen; Alzheimer's Drug Discovery Foundation; Alzheimer's... and other collaborators

Completed

Perfusion by Arterial Spin Labelling Following Single Dose Tadalafil in Small Vessel Disease (PASTIS) Trial (PASTIS)

Dementia, Vascular

United Kingdom
Berlin Heart, Inc

Unknown

Registry to Monitor Berlin Heart EXCOR® Pediatric VAD as a Bridge to Cardiac Transplantation.

Ventricular Dysfunction | Ventricular Dysfunction, Left | Ventricular Dysfunction, Right

United States
Loughborough University
Teesside University

Completed

Individual Variability of Coronary Heart Disease Risk Markers and Sleep Responses to Exercise

Sleep | Blood Pressure | Coronary Heart Disease | Cardiovascular Risk Factor | Arterial Stiffness

United Kingdom
Abbott Medical Devices

Completed

CardioMEMS HF System Post Approval Study

Heart Failure | Congestive Heart Failure | Left-Sided Heart Failure

United States
National Health Service, United Kingdom

Completed

The Effect of Adding Exercise Training to Optimal Therapy in PAH

Pulmonary Arterial Hypertension

United Kingdom
ECRI bv
Boston Scientific Corporation; Philips Healthcare

Active, not recruiting

The OPTIMAL Randomized Controlled Trial (OPTIMAL)

Left Main Coronary Artery Stenosis

Spain, United Kingdom, Italy
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Investigation Into the Use of Ultrasound Technique in the Evaluation of Heart Disease

Healthy | Hypertrophic Cardiomyopathy | Left Ventricular Hypertrophy

United States
Cardiora Pty. Ltd.

Completed

CRD-102 for Right Heart Failure in Patients With Left Ventricular Assist Devices

Right Heart Failure | Left Ventricular Assist Device

United States
University Hospitals, Leicester

Terminated

Multicentre Study to Investigate the Performance of the Padd Device in the Assessment of Peripheral Arterial Disease

Peripheral Arterial Disease

United Kingdom
Actelion

Completed

Clinical Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction (MELODY-1)

Pulmonary Hypertension

United States, Austria, Belgium, Canada, Czechia, France, Germany, Israel, Italy, Spain, Switzerland
Sanofi

Completed

EURopean Trial In Atrial Fibrillation(AF) or Flutter (AFL) Patients Receiving Dronedarone for the maIntenance of Sinus Rhythm (EURIDIS) (EURIDIS)

Atrial Fibrillation | Atrial Flutter

France, Poland, Germany, Italy, Netherlands, Spain, Belgium, Czech Republic, United Kingdom, Denmark, Finland, Hungary
GE Healthcare
Quintiles, Inc.; H2O Clinical LLC

Completed

Open-label, Test-retest Study Assessing Reproducibility of Quantitative Measurements of Myocardial Uptake of AdreView.

Ventricular Dysfunction, Left | Heart Failure (HF)

United States
Yale University

Completed

Validation of the Gated Blood Pool SPECT: ERNA vs 3D Echo

Congestive Heart Failure | Ventricular Function, Left

United States
University of Salford
Northern Care Alliance NHS Foundation Trust

Completed

Assessing the Feasibility of Including Patients With Peripheral Artery Disease in to an Established Cardiac Rehabilitation Service.

Cardiovascular Diseases | Coronary Artery Disease | Peripheral Arterial Disease | Intermittent Claudication

United Kingdom
Icahn School of Medicine at Mount Sinai
Bristol-Myers Squibb

Completed

Antithrombotic Strategy Variability In ATrial Fibrillation and Obstructive Coronary Disease Revascularized With PCI - The AVIATOR 2 Registry

Non-valvular Atrial Fibrillation

United States
Coventry University
University Hospitals Coventry and Warwickshire NHS Trust

Completed

Home-based Circuit Training for People With Intermittent Claudication (WALKSTRONG)

Intermittent Claudication | Peripheral Artery Disease

United Kingdom
Northumbria University

Recruiting

Telehealth Exercise Training in Peripheral Arterial Disease - TEXT-PAD

Peripheral Arterial Disease | Intermittent Claudication | Behavior, Health | Exercise Intervention

United Kingdom
AtriCure, Inc.
Cardialysis BV

Active, not recruiting

Combined Endoscopic Epicardial and Percutaneous Endocardial Ablation Versus Repeated Catheter Ablation in Persistent and Longstanding Persistent Atrial Fibrillation (CEASE-AF)

Atrial Fibrillation | Persistent and Longstanding Persistent Atrial Fibrillation

Germany, United Kingdom, Netherlands, Czechia, Poland
Cardiff and Vale University Health Board
The European Vascular Research Collaborative (EVRC)

Not yet recruiting

Validating GLASS Score in Predicting Acute Limb Events in CLTI Patients (PROMOTEGLASS)

Chronic Limb-Threatening Ischemia

United Kingdom
University of Nebraska

Completed

Echo-guided Hemodynamic Management Strategy in Elderly Patients Undergoing Noncardiac Surgery

Ventricular Dysfunction, Left | Major Adverse Cardiac Events

United States

Clinical Trials on Left Atrial Dilatation in United Kingdom

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