Clinical Trials on Leukocyte Adhesion Deficiency Syndrome

Total 6009 results

David Williams

Active, not recruiting

Pilot and Feasibility Study of Hematopoietic Stem Cell Gene Transfer for the Wiskott-Aldrich Syndrome

Wiskott-Aldrich Syndrome

United States
Genethon
Institute of Child Health; Great Ormond Street Hospital for Children NHS Foundation...

Completed

Gene Therapy for Wiskott-Aldrich Syndrome (WAS)

Wiskott-Aldrich Syndrome

United Kingdom
GlaxoSmithKline

Completed

Targeted Literature Review and Subject Interviews in Wiskott-Aldrich Syndrome (WAS)

Wiskott-Aldrich Syndrome

United States
Genethon
Hôpital Necker-Enfants Malades

Completed

Gene Therapy for WAS

Wiskott-Aldrich Syndrome

France
Sidney Kimmel Cancer Center at Thomas Jefferson...

Withdrawn

Donor Stem Cell Boost in Treating Patients With Low Blood Cells After Donor Stem Cell Transplant

Anemia | Thrombocytopenia | Neutropenia | Hematopoietic/Lymphoid Cancer | Lymphopenia
Genethon

Active, not recruiting

Long Term Safety Follow up of Haematopoietic Stem Cell Gene Therapy for the Wiskott Aldrich Syndrome (WASFUP)

Wiskott-Aldrich Syndrome

United Kingdom, France
Capital Research Institute of Pediatrics

Unknown

Post-transplant Cyclophosphamide in Wiskott-Aldrich Syndrome

Wiskott-Aldrich Syndrome
St. Jude Children's Research Hospital

Completed

Haploidentical Hematopoietic Stem Cell Transplantation Patients With Wiskott-Aldrich Syndrome

Wiskott-Aldrich Syndrome

United States
Jongmin Lee

Completed

Presepsin as Detective Marker of Sepsis in Immunodeficiency ICU Patients (PREICU)

Sepsis | Immune Deficiency

Korea, Republic of
Chuncheon Sacred Heart Hospital

Completed

Glenohumeral Versus Subacromial Steroid Injections for Impingement Syndrome With Mild Shoulder Stiffness

Shoulder Impingement Syndrome | Adhesive Capsulitis of Shoulder

Korea, Republic of
Emory University

Completed

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Sickle Cell Disease | Fanconi Anemia | Hurler Syndrome | Chronic Granulomatous Disease | Severe Congenital Neutropenia | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Glanzmann Thrombasthenia | Shwachman-Diamond Syndrome | Thalassemia Major | Leukocyte... and other conditions

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Idiopathic CD4-Positive | T-Lymphocytopenia

United States
National Cancer Institute (NCI)

Completed

In Vitro Studies of Immunological and Stem Cell Function in Peripheral Blood Mononuclear Cells in Patients

Lymphoma | Leukemia | Neoplasm | Immunologic Deficiency Syndrome

United States
Federal Research Institute of Pediatric Hematology...

Recruiting

Efficacy and Safety of Romiplostim Versus Eltrombopag in the Treatment of Thrombocytopenia in Patients With Wiskott-Aldrich Syndrome

Wiskott-Aldrich Syndrome

Russian Federation
Weill Medical College of Cornell University
Novartis Pharmaceuticals

Terminated

Thrombocytopenia and Bleeding in Wiskott-Aldrich Syndrome (WAS) Patients (WAS)

Bleeding | Thrombocytopenia | Wiskott-Aldrich Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Completed

Posaconazole to Treat Invasive Fungal Infections

Granulomatous Disease, Chronic | Infection | Job's Syndrome

United States
Harvard School of Public Health (HSPH)
National Institute of Allergy and Infectious Diseases (NIAID); Fogarty International... and other collaborators

Completed

Safety of Cotrimoxazole in HIV- and HAART-exposed Infants

HIV Infections | Acquired Immunodeficiency Syndrome | Anemia | Neutropenia | Infant, Newborn

Botswana
Federal Research Institute of Pediatric Hematology...

Unknown

A Trial of Plerixafor/G-CSF as Additional Agents for Conditioning Before TCR Alpha/Beta Depleted HSCT in WAS Patients

Hematopoietic Stem Cell Transplantation | Wiskott-Aldrich Syndrome | Graft Failure

Russian Federation
National Institute of Allergy and Infectious Diseases...

Terminated

Interleukin-7 (CYT107) Treatment of Idiopathic CD4 Lymphocytopenia: Expansion of CD4 T Cells (ICICLE)

Idiopathic CD4+ T-Lymphocytopenia

United States
Federal Research Institute of Pediatric Hematology...

Completed

Romiplostim Treatment for Thrombocytopenia in Patients With Wiskott-Aldrich Syndrome.

Wiskott-Aldrich Syndrome

Russian Federation
Makerere University
Vaccine and Gene Therapy Institute, Florida

Completed

Atorvastatin for HAART Suboptimal Responders

Acquired Immune Deficiency Syndrome Virus
Guang'anmen Hospital of China Academy of Chinese...

Unknown

Clinical Trials on the Effect of Immunity 1 (Fuzheng 1) on Immune Reconstitution of HIV Patients

HIV Infections | Acquired Immune Deficiency Syndrome Virus

China
Soma Jyonouchi
Baylor College of Medicine

Completed

Interleukin-2 Treatment for Wiskott-Aldrich Syndrome (WAS)

X-linked Thrombocytopenia | Wiskott-Aldrich Syndrome (WAS)

United States
Issa, Abdulhamid Sayed, M.D.

Completed

Mini Lateral Shoulder Approach (MLSA)

Shoulder Impingement Syndrome | Rotator Cuff Tendinopathy | Adhesive Capsulitis and Frozen Shoulder Syndrome

Syrian Arab Republic
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Evaluation of Azidothymidine (AZT) in Children With Acquired Immune Deficiency Syndrome (AIDS) or AIDS Related Complex (ARC)

HIV Infections

United States
Gilead Sciences

Terminated

Two Part Study to Evaluate Pharmacokinetics, Safety, and Antiviral Activity of Elvitegravir Administered With a PI/r Background Regimen for ARV Treatment-Experienced Pediatric Participants

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, Thailand, Spain, Uganda, South Africa, Italy
Juan A. Arnaiz

Unknown

Immune Recovery in Advanced , ARV-naïve, HIV-1-infected Individuals Taking Dolutegravir or Ritonavir-boosted Darunavir

Acquired Immune Deficiency Syndrome Virus

Spain
Guang'anmen Hospital of China Academy of Chinese...

Unknown

The Effect of Combination of Traditional Chinese Medicine (TCM) and Highly Active Antiretroviral Therapy (HAART) on Immune Reconstitution of HIV/AIDS Patients

HIV Infections | Acquired Immune Deficiency Syndrome Virus

China
Guang'anmen Hospital of China Academy of Chinese...

Unknown

Research on Effect of Traditional Chinese Medicine (TCM) on Immune Reconstitution of HIV/AIDS Patients After Highly Active Antiretroviral Therapy (HAART)

HIV Infections | Acquired Immune Deficiency Syndrome Virus

China
Amgen

Completed

An Open-Label Phase I/II Study of Recombinant Granulocyte Colony Stimulating Factor (r-metHuG-CSF) and Recombinant Erythropoietin (rHuEPO) Given Subcutaneously Along With Zidovudine (AZT) to Patients With the Acquired Immune Deficiency Syndrome (AIDS) or Severe AIDS-Related Complex (ARC)

HIV Infections

United States
Lederle Laboratories

Completed

A Multi-Center, Open-Label, Ascending, Multiple Oral Dose, Safety, Tolerance and Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Patients With Acquired Immune Deficiency Syndrome (AIDS) or AIDS-Related Complex (ARC)

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of HIV-Negative Patients With Low CD4+ T Lymphocyte Counts

CD4 Lymphocytopenia | Idiopathic CD4 Positive T Lymphocytopenia

United States
Novartis Pharmaceuticals

No longer available

MAP to Provide Access to Nilotinib, for Patients With HES

Hypereosinophilic Syndrome (HES)
Prothya Biosolutions
Landsteiner Foundation for Blood Transfusion

Completed

Study on Mannan Binding Lectin (MBL) Substitution in MBL-Deficient Children With Chemotherapy-Induced Neutropenia

Neutropenia | MBL-Deficient

Netherlands
Gilead Sciences

Active, not recruiting

Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents and Virologically Suppressed Children

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, Thailand, Uganda, South Africa, Zimbabwe
Columbia University
National Institute of Mental Health (NIMH)

Completed

Multi-level Determinants of Starting ART Late: Aim 2 (LSTART)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Ethiopia
Peking University Third Hospital
China Academy of Chinese Medical Sciences; Beijing University of Chinese Medicine and other collaborators

Recruiting

Standard Scale for Syndrome Differentiation of Yin Deficiency Syndrome (SFYDS)

Yin Deficiency Syndrome

China
Steven E. Coutre
Novartis

Terminated

Phase II Gleevec Idiopathic Hypereosinophilic Syndrome

Eosinophilia | Hypereosinophilic Syndrome

United States
GlaxoSmithKline

Completed

A Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622

Hypereosinophilic Syndrome

United States, Poland, Spain, France, Belgium, Germany, Argentina, Russian Federation, Mexico, Italy, Brazil, United Kingdom, Romania
GlaxoSmithKline

Completed

Efficacy and Safety Study of Mepolizumab in Subjects With Severe Hypereosinophilic Syndrome (HES)

Hypereosinophilic Syndrome

United States, Poland, Spain, France, Belgium, Germany, Argentina, Russian Federation, Mexico, Italy, Brazil, United Kingdom, Romania
University Hospital, Lille

Completed

Identification of New Markers in the Hypereosinophilic Syndrome (SHE)

Hypereosinophilic Syndrome

France
Columbia University

Completed

Enhanced HIV Prevention in Couples: Feasibility Study #1 (EPIC)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Lesotho
Gilead Sciences

Recruiting

Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, South Africa, Argentina, Panama, Thailand, Zimbabwe, United Kingdom, Uganda
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Exploring Novel Mechanisms of Vaccine Failure LAIV Pilot Study (LAIV)

Acquired Immune Deficiency Syndrome Virus

United Kingdom
Columbia University
Centers for Disease Control and Prevention

Completed

Pediatric Enhanced Surveillance Study (PESS)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

South Africa
Columbia University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Enhanced Prevention in Couples: Feasibility Study #2 (EPIC)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Lesotho
Columbia University
National Institute of Mental Health (NIMH)

Completed

Multi-level Determinants of Starting ART Late: Aim 3 (LSTART)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Ethiopia
Columbia University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Enhanced HIV Prevention in Couples: Feasibility Study #3 (EPIC)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Lesotho
Caribbean Health Research Council
The University of The West Indies

Completed

Impact of Nutrition Intervention on HIV/AIDS Infected Patients (INI)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Jamaica
Federal Research Institute of Pediatric Hematology...

Not yet recruiting

Total Lymphoid Irradiation Pre-HSCT in Severe Congenital Neutropenia

Severe Congenital Neutropenia | GATA2 Deficiency

Russian Federation

Clinical Trials on Leukocyte Adhesion Deficiency Syndrome

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