Clinical Trials on Resistant Chronic GVHD

Total 37763 results

Xuzhou Medical University

Recruiting

Safety and Efficacy of Iguratimod in the Treatment of Chronic GVHD

cGVHD

China
Chinese PLA General Hospital

Recruiting

Efficacy and Safety Study of 4-Day ATG Regimen for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT

aGVHD | cGVHD

China
Hadassah Medical Organization

Completed

Alefacept for Chronic Graft Versus Host Disease

Resistant Chronic GVHD

Israel
Shanghai Jiao Tong University School of Medicine
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Unknown

Valproic Acid With Methylprenisonlone for the Treatment of Acute GVHD

Peripheral Blood Stem Cell Transplantation | aGVHD

China
Equillium
Biocon Limited

Recruiting

A Study of Itolizumab in Combination With Corticosteroids for the First-Line Treatment of Acute Graft Versus Host Disease (EQUATOR)

Graft Versus Host Disease | GVHD | aGVHD | Acute-graft-versus-host Disease | Acute GVHD

United States, Korea, Republic of, Germany, Israel, Spain, Belgium, Italy, Australia, France, Canada, Portugal, New Zealand
Equillium
Biocon Limited

Recruiting

A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD (EQUATE)

GVHD | GVHD, Acute | aGVHD | Acute-graft-versus-host Disease

United States
daphne brockington

Unknown

Continuous Alloreactive T Cell Depletion and Regulatory T Cell Expansion for the Treatment of Steroid-refractory or Dependent Chronic GVHD (CARE)

Chronic GVHD After HCT for Cancer or Immune Disease

Canada
Ciusss de L'Est de l'Île de Montréal
Centre hospitalier de l'Université de Montréal (CHUM)

Not yet recruiting

Improvement of Women's Health After Allogeneic Stem Cell Transplantation (SaFeGreff)

GVHD, Chronic
Fujian Medical University

Unknown

MSC for Severe aGVHD

Steroid-resistant Severe aGVHD

China
Rigshospitalet, Denmark
Novo Nordisk A/S

Completed

Systematic Symptom Identification With Disease Specific PROM to Assess Symptoms of Chronic GVHD in Outpatient Care in Patients Post HSCT (SIMPly-CARE)

Hematological Malignancy | GVHD, Chronic

Denmark
University of Salamanca

Recruiting

Physiotherapy and Therapeutic Exercise Program in Graft-versus-host Disease (GvHD)

GVHD, Chronic | GVHD,Acute

Spain
Shanghai General Hospital, Shanghai Jiao Tong University...

Recruiting

SHR0302 and Steroid as First Line Therapy for Chronic GVHD

Chronic GVHD

China
Tata Memorial Centre

Recruiting

Leflunomide for Musculoskeletal GVHD After Allogeneic Stem Cell Transplant

Musculoskeletal Disease Other | GVHD, Chronic

India
Fred Hutchinson Cancer Center

Active, not recruiting

Chronic GVHD Response Measures Validation

Graft vs Host Disease

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Universitätsklinikum Hamburg-Eppendorf; The Chaim Sheba Medical Center; Hospital...

Completed

Electronic Database for the Follow up of the ATG_FamilyStudy (AFF)

Acute Leukemia | Stem Cell Transplant Complications | GVHD, Chronic

Italy
Nationwide Children's Hospital

Terminated

Infliximab and Basiliximab for Treatment of Steroid Refractory Acute Graft Versus Host Disease

Graft Versus Host Disease | Acute GVH Disease | Steroid Refractory GVHD

United States
Shanghai Jiao Tong University School of Medicine

Completed

PT-CY With or Without Low-dose ATG for Lymphoid Malignancies Undergoing Allo-HSCT

GVHD, Acute

China
Mats Remberger
The Swedish Research Council

Recruiting

Decidua Stroma Cells for Steroid Resistent Acute Graft-versus-host Disease After Allo-HSCT (2017-00355)

GVHD, Acute

Sweden, Norway, Denmark
MaaT Pharma

Recruiting

Prospective Interventional Study Exploring the Microbiota Recolonization in SR-GvHD Patients Receiving MaaT013 (ORION)

Steroid Refractory GVHD | Intestinal GVHD

France
Massachusetts General Hospital
Novartis

Terminated

Phase I Trial of LDE225 for Steroid-refractory Chronic GVHD After Allogeneic HSCT

Graft Versus Host Disease

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Multiparametric Ultrasound Study in Diagnosing GvHD (ECO-STEM)

Intestinal GVHD

Italy
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801)

Chronic GVHD

United States
CSL Behring

Terminated

Exploratory Safety Study of ALD518 in Subjects With Steroid-refractory Acute Graft Versus Host Disease (GVHD) (ALD518-010)

Acute GvHD

United States
Weill Medical College of Cornell University

Terminated

Phase II Study of Tocilizumab for Patients With Glucocorticoid-refractory Acute GVHD After Allogeneic Hematopoetic Stem Cell Transplant (HSCT)

Glucocorticosteroid Refractory Acute GVHD

United States
The Korean Society of Hematopoietic Stem Cell Transplantation
Hoffmann-La Roche

Unknown

Study of Rituximab in Patients With Steroid-Refractory Chronic Graft-Versus-Host Disease

Steroid-Refractory Chronic GVHD

Korea, Republic of
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids (MTX-aGVHD)

Stem Cell Transplant Complications | GVHD, Acute | GVH - Graft Versus Host Reaction | Allogeneic Disease

France
M.D. Anderson Cancer Center

Completed

Feasibility Study of Collecting Multicenter Chronic GVHD Data

Graft-Versus-Host Disease

United States
Nationwide Children's Hospital
Daisy Foundation

Completed

70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014 (70% EtOH)

GVHD | Hematopoietic Stem Cell Transplant

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

PROACTIVE: Preventing Acute/Chronic GVHD With TocIlizumab Combined With GVHD Prophylaxis Post allogEneic Transplant

Hematologic Malignancy

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Immune Monitoring After Allogeneic Hematopoietic Stem Cell Transplantation

GVHD | Allogeneic Stem Cell Transplantation

Italy
Duke University

Recruiting

Prebiotic Galacto-oligosaccharide and Acute GVHD

Acute GVHD

United States
Washington University School of Medicine

Recruiting

Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease

Chronic GVHD | Acute Graft-versus-host Disease | Chronic Graft-versus-host Disease | Acute GVHD

United States
Shanghai iCELL Biotechnology Co., Ltd, Shanghai...

Not yet recruiting

Safety and Efficacy Study of hAESCs Therapy for aGVHD (aGVHD，hAESCs)

GVHD,Acute
UNC Lineberger Comprehensive Cancer Center
University of North Carolina, Chapel Hill

Completed

Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplant (HCT)

Acute GVHD

United States
Wang Xin

Not yet recruiting

Prophylaxis of Graft-versus-host Disease With Anti-CD25 Antibody in Patients Underwent HSCT

GVHD

China
Hackensack Meridian Health

Terminated

Study of TelmisartanFor the Prevention of Acute GVHD Post Allogeneic Hematopoietic Stem Cell Transplantation

GVHD

United States
European Society for Blood and Marrow Transplantation
Mallinckrodt

Completed

ECP Combination Study

Steroid Refractory GVHD

Spain, United Kingdom, Sweden, Italy, Israel, France, Denmark, Germany, Poland, Turkey, Romania, Belgium, Greece, Russian Federation
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated Cytopenias

Immune Mediated Anemia | Immune Mediated Thrombocytopenia | Chronic GVHD

United States
Chinese PLA General Hospital

Recruiting

Role of aGVHD Biomarkers on aGVHD Risks (GVHD)

Biomarker | GVHD,Acute

China
Ossium Health, Inc.

Withdrawn

Mesenchymal Stem Cells (MSCs) for Steroid Refractory Acute GVHD (SR-aGVHD)

GVHD,Acute
Shenzhen Xbiome Biotech Co., Ltd.

Not yet recruiting

Fecal Microbiota Transplant (FMT) Capsule for Improving the Efficacy of GI-aGVHD

GVHD
University of Minnesota

Withdrawn

Allogeneic Skin Grafting

GVHD

United States
IRCCS Policlinico S. Matteo

Completed

Comparison of Two Automated Mononuclear Collection Systems in Patients Undergoing Extracorporeal Photochemotherapy. A Cross-over Equivalence Study. (MNC_CMNC) (CMNC_MNC)

GvHD | Lung Graft Dysfunction

Italy
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias

Immune Mediated Anemia | Immune Mediated Thrombocytopenia | Chronic GVHD

United States
H. Lee Moffitt Cancer Center and Research Institute
Bristol-Myers Squibb

Completed

CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

GVHD | Graft-versus-host-disease | GVHD, Acute

United States
Mesoblast, Inc.
Quintiles, Inc.

Completed

A Prospective Study of Remestemcel-L, Ex-vivo Cultured Adult Human Mesenchymal Stromal Cells, for the Treatment of Pediatric Participants Who Have Failed to Respond to Steroid Treatment for Acute Graft-Versus-Host Disease (aGVHD)

Grade B aGVHD | Grade C aGVHD | Grade D aGVHD

United States
Henry Ford Health System

Completed

Immuno-regulatory Profiling of T Cells in GVHD Treated With Extracorporeal Photopheresis

GVHD

United States
ElsaLys Biotech

Not yet recruiting

Evaluation of EFficacy and SaFEty of Leukotac (Inolimomab) in Pediatric Patients With SR-aGvHD (EiFFEL)

Steroid Refractory GVHD
St. Petersburg State Pavlov Medical University

Recruiting

Fecal Microbiota Transplantation With Ruxolitinib and Steroids as an Upfront Treatment of Severe Acute Intestinal GVHD (JAK-FMT)

Intestinal GVHD

Russian Federation
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

A Study to Evaluate Steroid-free Treatment for Standard-Risk aGVHD (BMT CTN 1501)

Acute GVHD

United States

Clinical Trials on Resistant Chronic GVHD

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