Clinical Trials on Li-Fraumeni Syndrome in United Kingdom

Total 14064 results

Abramson Cancer Center of the University of Pennsylvania
Children's Hospital of Philadelphia

Recruiting

Li-Fraumeni Syndrome/TP53 Biobank

Li-Fraumeni Syndrome | Li-Fraumeni-Like Syndrome

United States
Institute of Cancer Research, United Kingdom
Cancer Research UK; National Institute for Health Research, United Kingdom

Completed

Magnetic Resonance Imaging Screening in Li Fraumeni Syndrome (SIGNIFY)

Li-Fraumeni Syndrome

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Willingness to Participate in a Trial Comparing Standard Genetic Counseling Versus Personalized Genetic Counseling

Li-Fraumeni Syndrome

United States
Royal Marsden NHS Foundation Trust

Recruiting

Inherited Cancer Early Diagnosis (ICED) Study (ICED)

Lynch Syndrome | Familial Adenomatous Polyposis | Hereditary Diffuse Gastric Cancer | Peutz-Jeghers Syndrome | Cowden Syndrome | Li Fraumeni Syndrome | MutYH-associated Polyposis | SMAD4 Gene Mutation

United Kingdom
Dana-Farber Cancer Institute

Active, not recruiting

Screening With Whole Body MRI For Detection Of Primary Tumors In Children And Adults With Li-Fraumeni Syndrome (LFS) And Other Cancer Predisposition Syndromes

Li-Fraumeni Syndrome

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome

Li-Fraumeni Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Clinical and Genetic Studies of Li-Fraumeni Syndrome

Neoplasms | Li-Fraumeni Syndrome | Tp53 Mutations

United States
Scripps Health
J. Craig Venter Institute

Completed

Biomarker Monitoring in TP53 Mutation Carriers

Li-Fraumeni Syndrome | Hereditary Cancer Syndromes | TP53 Gene Germline Mutation Carrier

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Baylor College of Medicine; City of Hope Medical...

Recruiting

Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress (LiFT_UP)

TP53 Gene Mutation | Li-Fraumeni Syndrome | Hereditary Cancer Syndrome | Mosaicism | Clonal Hematopoiesis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Role of p53 Gene in Metabolism Regulation in Patients With Li-Fraumeni Syndrome

Mitochondrial Disorders | Li-Fraumeni Syndrome | Carriers of p53 Mutation

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome

Cancer | Muscle Weakness | Skin Fibroblasts

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

Parkinson's Disease | Atherosclerosis | Cardiomyopathy | Li-Fraumeni Syndrome | Cardiovascular Capacity

United States
St. Bartholomew's Hospital

Unknown

Erythropoietin (EPO) and Granulocyte-Colony Stimulating Factor (G-CSF) for Low-Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes

United Kingdom
Brighton and Sussex University Hospitals NHS Trust
Medtronic Vascular

Completed

Revascularisation or Medical Therapy in Elderly Patients With Acute Anginal Syndromes (RINCAL)

Acute Coronary Syndromes

United Kingdom
University College, London
King's College London; King's College Hospital NHS Trust; University of Oxford; Great Ormond Street Hospital for Children NHS Foundation Trust

Recruiting

Children's Adaptive Deep Brain Stimulation for Epilepsy Trial (CADET): Pilot (CADET Pilot)

Epilepsy | Lennox-Gastaut Syndrome, Intractable

United Kingdom
University of Portsmouth
Portsmouth Hospitals NHS Trust

Not yet recruiting

The Effects of Prolonged Head-Down Tilt Lithotomy Position on Lower Limb Haemodynamics (HELP)

Compartment Syndrome Nontraumatic Lower Extremity

United Kingdom
Oxford University Hospitals NHS Trust

Unknown

Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants

Myelodysplastic Syndromes | Leukemia

United Kingdom
The Leeds Teaching Hospitals NHS Trust

Unknown

Cubital Tunnel Syndrome and Diffusion MRI: A Proof of Concept Study

Cubital Tunnel Syndrome

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Recruiting

Low-dose Interleukin-2 for the Reduction of Vascular Inflammation in Acute Coronary Syndromes - IVORY (IVORY)

Acute Coronary Syndromes

United Kingdom
King's College Hospital NHS Trust

Completed

The Efficacy and Safety of Lenalidomide Monotherapy in Red Blood Cell Transfusion Dependent Subjects With Myelodysplastic Syndrome (MDS) Associated With Del (5q) Abnormality

Myelodysplastic Syndromes

United Kingdom
Imperial College London
The Drummond Foundation (RAMC charity)

Recruiting

Chemical Analysis of Limb Microfluidics (CALM)

Compartment Syndrome of Leg | Limb Ischemia

United Kingdom
Allergan

Terminated

Clinical Study to Evaluate Tear Characteristics Following Acute TrueTear™ Use

Dry Eye Syndromes

United Kingdom
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
Barts & The London NHS Trust
Cancer Research UK; Amgen

Unknown

Comparison Study of Standard Care Against Combination of Growth Factors Agents for Low-risk Myelodysplastic Syndromes (REGIME)

Myelodysplastic Syndrome

United Kingdom
University Hospital Birmingham NHS Foundation Trust

Completed

The Application of Near Infrared Spectroscopy (NIRS) in the Detection of Lower Limb Compartment Syndrome

Compartment Syndrome

United Kingdom
University of the West of England
Royal United Hospital Bath NHS Trust

Completed

Self Soft Tissue Therapy for Fibromyalgia Syndrome

Fibromyalgia Syndrome

United Kingdom
King's College Hospital NHS Trust

Terminated

Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin (FB-ATG)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
University College, London
Barts & The London NHS Trust

Unknown

Coronary Mortality in South Asians: Aetiologic and Prognostic Effects (CALIBER)

Acute Coronary Syndromes

United Kingdom
University College, London

Completed

SS-INQ Information Needs Questionnaire in Sjögren's Syndrome (SS-INQ)

Sjögren's Syndrome

United Kingdom
John Carroll University
University Hospital Southampton NHS Foundation Trust

Active, not recruiting

Development and Validation of an Online Neurobehavioral Evaluation Tool for PTEN Patients

PTEN Hamartoma Tumor Syndrome

United States, United Kingdom
Aston University

Not yet recruiting

Photobiomodulation With REd vs BluE Light (REBEL)

Dry Eye Syndromes | Meibomian Gland Dysfunction | Blepharitis

United Kingdom
Imperial College London

Withdrawn

Liraglutide on Decreasing Parenteral Support in Short Bowel Patients (SLIPS) (SLIPS)

Short Bowel Syndrome

United Kingdom
Allergan

Completed

Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye Symptoms

Dry Eye Syndromes

United Kingdom
University of Suffolk

Recruiting

The 5Ad Diet for Functional Bowel Disorders

Irritable Bowel Syndrome | Food Intolerance | Functional Bowel Disorder | Food Intolerance Syndromes

United Kingdom
Millennium Pharmaceuticals, Inc.

Completed

Study of TAK-935 as an Adjunctive Therapy in Adult Participants With Complex Regional Pain Syndrome (CRPS)

Complex Regional Pain Syndrome

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

Gastrectomy, Eating Behaviour and GLP-1

Gastric Cancer | Dumping Syndrome

United Kingdom
Medical Research Council

Completed

Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myeloid Leukemia

Myelodysplastic Syndromes | Leukemia

United Kingdom
St Mark's Hospital Foundation

Completed

Citrulline: A Plasmatic Marker to Assess and Monitor Small Bowel Crohn's Disease Patients

Celiac Disease | Malabsorption Syndromes | Crohn's Disease | Short Bowel Syndrome

United Kingdom
University of Aberdeen
NHS Grampian; Softcell Medical Ltd

Not yet recruiting

Real-time Soft Tissue Assessment Using a Technologically Advanced pH Monitoring System (SoftpH)

Acute Compartment Syndrome

United Kingdom
Genzyme, a Sanofi Company

Terminated

Rabbit Anti-thymocyte Globulin in the Treatment of Patients With Low to Intermediate-1 Risk Myelodysplastic Syndrome (RISE)

Myelodysplastic Syndrome (MDS)

Germany, United Kingdom, France, Netherlands
Kirby Institute

Completed

Pharmacokinetics of Lopinavir/Ritonavir at Three Different Doses. (ENCORE3)

Acquired Immunodeficiency Syndrome

United Kingdom
Optometric Technology Group Ltd
Allergan

Completed

Efficacy Study of a New Eyedrop on Silicone Hydrogel Contact Lens Wearers With Dry Eye Complaints

Contact Lens Related Dry Eye Syndrome

United Kingdom
Allergan

Completed

A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry Eye

Dry Eye Syndromes | Keratoconjunctivitis Sicca

France, United Kingdom
Keele University
Arthritis Research UK

Completed

Injection Versus Splinting in Carpal Tunnel Syndrome (INSTinCTS)

Carpal Tunnel Syndrome (CTS)

United Kingdom
King's College London
King's College Hospital NHS Trust

Unknown

Use of Decitabine in Myelodysplastic Syndrome (MDS) Following Azacitidine (AZA) Failure (DEC-MDS)

Acute Myeloid Leukemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome

United Kingdom
Jing Advanced Massage Training
Medway NHS Foundation Trust

Completed

Clinical Massage Therapy as a Treatment for Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

United Kingdom
East Kent Hospitals University NHS Foundation Trust

Completed

Ultrasound Therapy for Carpal Tunnel Syndrome (CTS) (CTS)

Carpal Tunnel Syndrome

United Kingdom
King's College Hospital NHS Trust

Unknown

Prophylactic DLI for the Prevention of Relapse Post HSCT in Patients With High Risk Myeloid Malignancy (PRO-DLI)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
University Hospitals, Leicester

Completed

Abdominal Plane Blocks (APB) in Chronic Abdominal Pain (CAP)

Abdominal Pain | Abdominal Myofascial Pain Syndrome (AMPS) | Abdominal Plane Blocks (APB)

United Kingdom
Sheffield Children's NHS Foundation Trust

Completed

Paediatric Oximetry Algorithms - Normative Data Collection

Sleep Apnea Syndromes in Children

United Kingdom

Clinical Trials on Li-Fraumeni Syndrome in United Kingdom

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