Search clinical trials for: ORM-12471

Total 8380 results

Orion Corporation, Orion Pharma

Terminated

Efficacy of ORM-12741 for Prevention of Raynaud's Phenomenon (REINO)

Raynaud's Phenomenon

United Kingdom
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study of Multiple Doses of ORM-12741 (Nebula PK 2)

Healthy

Finland
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study of Single Doses of ORM-12741 (Nebula PK 1)

Healthy

Finland
Orion Corporation, Orion Pharma

Completed

Safety and Efficacy of ORM-12741 in Patients With Alzheimer's Disease (ALPO)

Alzheimer's Disease

Finland
Orion Corporation, Orion Pharma

Completed

Safety and Pharmacokinetic Study With Multiple Ascending Doses of ORM-12741

Healthy

France
Orion Corporation, Orion Pharma

Completed

Early Phase I Microdosing Study of ORM-14540 and ORM-12741

Healthy

Finland
Orion Corporation, Orion Pharma

Completed

Safety and Tolerability Study With Single Ascending Doses of ORM-12741

Healthy

France
Orion Corporation, Orion Pharma

Completed

A PET Study With ORM-12741

Healthy

Finland
Orion Corporation, Orion Pharma

Completed

Safety and Tolerability Study With Multiple Ascending Doses of ORM-12741

Healthy

France
Orion Corporation, Orion Pharma
Janssen Pharmaceuticals

Completed

Efficacy of ORM-12741 on Agitation/Aggression Symptoms in Alzheimer's Disease (Nebula)

Alzheimer's Disease

Finland
Orion Corporation, Orion Pharma

Completed

Excretion Balance and Metabolism After a Single Oral Dose of 14C-Labelled ORM-12741 (ALMAS)

Healthy Male Volunteers

Netherlands
Orion Corporation, Orion Pharma

Completed

Pharmacokinetic Study of ORM-12741 in Healthy Volunteers

Healthy Volunteers

Finland
University of Cape Town
University of Oxford; Orion Corporation, Orion Pharma

Completed

Single-dose Novel Selective alpha2c Antagonist Pharmaco-MRI Study in Healthy Volunteers (SNAP_MRI)

Healthy Volunteer

South Africa
GlycoMimetics Incorporated

Completed

Placebo-controlled Single Dose Study to Evaluate Safety and Pharmacokinetics of GMI-1271 in Healthy Volunteers

Healthy Adult Subjects

United States
GlycoMimetics Incorporated

Completed

A Study to Determine the Efficacy, Safety and Pharmacokinetics of GMI-1271 as Adjunct to Standard of Care for the Treatment of Multiple Myeloma

Multiple Myeloma

Ireland, Denmark, United Kingdom, Germany
Apollomics Inc.
Zhejiang CrownMab Biotech Co. Ltd

Recruiting

Study to Evaluate PK and Safety With Uproleselan Combined With Chemotherapy to Treat Chinese R/R AML Patients

Relapsed/Refractory AML

China
Apollomics Inc.
Zhejiang CrownMab Biotech Co. Ltd

Recruiting

Study to Evaluate the Efficacy of Uproleselan in Combination With Chemotherapy in Chinese Patients With R/R AML

Relapsed/Refractory AML

China
Dong-A ST Co., Ltd.

Completed

A Study To Evaluate The Safety,Tolerability, PK and PD Of DA-1241 In Healthy Male Subjects

Diabetes Mellitus, Type 2

United States
New York Institute of Technology
American Osteopathic Association

Active, not recruiting

Effect of Osteopathic Manipulative Medicine on Parkinson Disease

Parkinson Disease

United States
NeuroBo Pharmaceuticals Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed NASH

NON-ALCOHOLIC STEATOHEPATITIS

United States
GlycoMimetics Incorporated
Celerion

Completed

A Study to Evaluate the PK, Safety and Tolerability of GMI-1271 With and Without Filgrastim in Healthy Adult Subjects

Healthy Volunteers

United States
Assistance Publique - Hôpitaux de Paris

Completed

Interest of elastoFRM With Force Measure by MRI on Patients With Hepatocellular Cancer (FORCE)

Hepatocellular Cancer

France
Government of Jersey
Liverpool John Moores University; Breathworks CIC; Primary Care Body (Jersey,...

Enrolling by invitation

Contribution of Online Stress and Pain Mindfulness Treatment to ACT Process Change and Outcomes in Chronic Pain

Chronic Pain

Jersey
Midwest Cardiovascular Research Foundation

Completed

JET-RANGER Trial - JETStream Atherectomy With Adjunctive Paclitaxel-Coated Balloon Angioplasty vs Plain Old Balloon Angioplasty Followed by Paclitaxel-Coated Balloon

Peripheral Vascular Disease

United States
TaiwanJ Pharmaceuticals Co., Ltd

Unknown

A Pharmacokinetic Study of JKB-122 Tablets Compared to Capsule

Autoimmune Hepatitis
Turku University Hospital
Helsinki University Central Hospital; Oulu University Hospital; Kuopio University... and other collaborators

Recruiting

Scandinavian Olecranon Research in the Elderly

Olecranon Fracture

Finland, Sweden
ResMed

Completed

Narval CC Mandibular Repositioning Device in the Second-line Treatment of Severe Obstructive Sleep Apnea Hypopnea (OSAH) (ORCADES)

Obstructive Sleep Apnea Syndrome

France
Duke University
Abbott Medical Devices

Completed

Does Echocardiographically Guided Ventriculo-Ventricular Optimization Yield a Sustained Improvement in Echocardiographic Parameters in Cardiac Resynchronization Therapy Patients? (DEVISE CRT) (Devise-CRT)

Heart Failure | Cardiomyopathy

United States
GlycoMimetics Incorporated
University of Michigan

Terminated

Study to Assess Safety, Tolerability, and Efficacy of GMI-1271 in Patients With Calf-level Deep Venous Thrombosis (DVT)

Deep Venous Thrombosis

United States
GlycoMimetics Incorporated
University of Michigan

Completed

Phase I Study to Assess Safety and Pharmacokinetics of GMI-1271 in Healthy Adult Subjects

Healthy Volunteers

United States
Istituto Scientifico Romagnolo per lo Studio e...

Completed

Sequential Treatment Strategy for Metastatic Colorectal Cancer (ITACa)

Metastatic Colorectal Cancer

Italy
McMaster University
St. Joseph's Healthcare Hamilton; Hamilton Health Sciences Corporation

Unknown

Axillary Reverse Mapping (ARM) Technique (ARM)

Invasive Breast Cancer | Ductal Carcinoma in Situ of the Breast

Canada
Memorial Sloan Kettering Cancer Center

Completed

Exercise Program of Breast Cancer Patients Undergoing Chemotherapy With or Without Radiation

Breast Cancer

United States
Rhythm Pharmaceuticals, Inc.

Recruiting

A Study of RM-718 in Healthy Subjects and in Patients With HO

Hypothalamic Obesity

United States
Johns Hopkins Bloomberg School of Public Health

Completed

Water, Sanitation, and Hygiene Mobile Health Messages as an Innovative Tool to Facilitate Behavior Change (CHoBI7)

Cholera

Bangladesh
Orum Therapeutics USA, Inc.

Recruiting

Study of ORM-5029 in Subjects With HER2-Expressing Advanced Solid Tumors

HER2-positive Breast Cancer | HER-2 Gene Amplification | HER2 Gene Mutation | HER-2 Protein Overexpression

United States
Clear Guide Medical
Johns Hopkins University

Withdrawn

Modality Augmentation for Navigation: Intuitive Fusion With Optical Lightweight Device (US/CBCT) (MANIFOLD II)

Hepatic Biopsy or Ablation
Clear Guide Medical
University of Maryland

Withdrawn

Modality Augmentation for Navigation: Intuitive Fusion With Optical Lightweight Device (US/MR) (MANIFOLD I)

Renal Biopsy or Ablation
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital; GlycoMimetics Incorporated

Completed

Uproleselan (GMI-1271) for GI Toxicity Prophylaxis During Melphalan-Conditioned Autologous Hematopoietic Cell Transplantation (Auto-HCT) for Multiple Myeloma (MM)

Multiple Myeloma

United States
Université de Montréal
University Hospital, Montpellier; Groupe Hospitalier Pitie-Salpetriere

Completed

Comparative Efficacy Study of Titratable Versus Active Mandibular Advancement Splint in Sleep Apnea (SOMNYX)

Obstructive Sleep Apnea

France, Canada
VA Office of Research and Development

Recruiting

Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

Obstructive Sleep Apnea | OSA COPD Overlap Syndrome

United States
HighField Biopharmaceuticals Corporation
Tigermed Consulting Co., Ltd

Recruiting

Tolerability and Safety of HF1K16 Injection in Patients With Refractory Solid Tumors

Solid Tumor, Adult

China
Fondazione IRCCS Istituto Nazionale dei Tumori,...
Federico II University; Humanitas Clinical and Research Center; Istituto Oncologico... and other collaborators

Recruiting

Targeting Triple Negative BREAst Cancer Metabolism With a Combination of Chemoimmunotherapy and a FASTing-like Approach in the Preoperative Setting: the BREAKFAST 2 Trial (BREAKFAST-2)

Breast Cancer | Triple Negative Breast Cancer | Fasting | Dietary Exposure

Italy
Hopital Foch

Terminated

Comparison of Two Oral Appliances in the Treatment of Sleep Apnea Syndrome

Obstructive Sleep Apnea

France
Orion Corporation, Orion Pharma

Completed

Suitability of 11C-ORM-13070 as a PET Tracer

Healthy

Finland
Hôpital NOVO

Completed

Evaluation of Positioning Protocols on a Wheelchair in Hemiplegic Patients (POSIT-HEMI)

Hemiplegia and/or Hemiparesis Following Stroke

France
Washington University School of Medicine

Active, not recruiting

Returning Research Results That Indicate Risk of Alzheimer Disease Dementia to Healthy Participants in Longitudinal Studies (WeSHARE)

Alzheimer Disease | Dementia of Alzheimer Type

United States
Shandong Suncadia Medicine Co., Ltd.

Completed

A HR20031 BE Study on Healthy Subjects

Type 2 Diabetes

China
Centre Leon Berard
National Cancer Institute, France; Fondation de France; Cancéropôle Lyon Auvergne... and other collaborators

Completed

Impact of Nutritional Intervention in Women With Breast Cancer Under Adjuvant Chemotherapy (PASAPAS)

Breast Cancer | Adequate Physical Condition

France
Novartis Pharmaceuticals

Completed

This Was a Dose-finding Study to Evaluate Efficacy and Safety of LOU064 in Patients With CSU Inadequately Controlled by H1-antihistamines

Chronic Spontaneous Urticaria

United States, Belgium, United Kingdom, Germany, Hungary, Spain, France, Turkey, Canada, Czechia, Netherlands, Poland, Japan, Russian Federation, Argentina, Denmark, Slovakia

Search clinical trials for: ORM-12471

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