Clinical Trials on Li-Fraumeniho syndrom

Total 34217 results

University College, London
University of Iowa

Unknown

Muscle MRI in Charcot Mary Tooth Disease: a Prospective Cohort Study

Charcot-Marie-Tooth Disease, Type IA | Charcot-Marie-Tooth Disease Type 2A | Charcot-Marie-Tooth Disease, Type IB | Charcot-Marie-Tooth Disease, Type X

United Kingdom
New York Medical College

Terminated

ODSH + ICE Chemotherapy in Pediatric Solid Tumors

Sarcoma | Neuroblastoma | Wilms' Tumor | Refractory Solid Tumor | Recurrent Solid Tumor

United States
University Hospital, Bonn

Unknown

Incidence and Effects of Sleep Apnea on Intracerebral Aneurysms (IESA)

Comorbidities | Sleep Apnea (Defined as Apnea Hypopnea Index > 5/h) | Intracranial Aneurysm Size | Blood Pressure Medication | Complications (Subarachnoid Hemorrhage)

Germany
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Homocysteine and Progression of Atherosclerosis

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Cerebrovascular Disorders | Peripheral Vascular Diseases | Atherosclerosis | Hyperhomocysteinemia
University of Sao Paulo

Unknown

Small Bowel Endoscopic Evaluation in Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis

Brazil
Chinese Pulmonary Vascular Disease Research Group

Completed

Long-term Effects of CPAP on Lipidemia and Hs-CRP Levels in OSA Patients

Obstructive Sleep Apnea | Coronary Heart Disease

China
St George's, University of London

Terminated

Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical Endometrial Hyperplasia and Endometrial Cancer in Women With Hereditary Non-Polyposis Colorectal Cancer or Lynch Syndrome

Endometrial Cancer | Hereditary Non-polyposis Colon Cancer (hmsh2, hmlh1, hpms1, hpms2)

United Kingdom
ARCAGY/ GINECO GROUP

Completed

Use of FACT-GOG/NTX Questionnaire in Peripheral Neurotoxicity & Validation of a French Version of This Questionnaire

Peritoneal Neoplasms | Ovarian Cancer | Fallopian Tube Cancer

France
Children's Hospitals and Clinics of Minnesota
M.D. Anderson Cancer Center; Washington University School of Medicine; Dana-Farber... and other collaborators

Recruiting

International PPB/DICER1 Registry

Neuroblastoma | Thyroid Carcinoma | Pineoblastoma | Wilms Tumor | Embryonal Rhabdomyosarcoma | Ovarian Sarcoma | Sertoli-Leydig Cell Tumor | Pleuropulmonary Blastoma | Gynandroblastoma | DICER1 Syndrome | Cystic Nephroma | Renal Sarcoma | Nodular Hyperplasia of Thyroid | Nasal Chondromesenchymal Hamartoma | Ciliary Body... and other conditions

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Unknown

Quality of Life and Care Needs of Patients With Persistent or Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Peritoneal Cancer

Fatigue | Anxiety | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Stage I Ovarian Cancer AJCC v6 and v7 | Stage IA Fallopian Tube Cancer AJCC v6 and v7 | Stage IB Fallopian Tube Cancer AJCC v6 and v7 | Stage IC Fallopian Tube Cancer AJCC... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride, Carboplatin, Dexamethasone, and Rituximab in Treating Patients With Previously Treated Lymphoid Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
City of Hope Medical Center

Terminated

Vorinostat and Lenalidomide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Travere Therapeutics, Inc.

Recruiting

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases (EPPIK)

Focal Segmental Glomerulosclerosis | Immunoglobulin A Nephropathy | Minimal Change Disease | Alport Syndrome | IgA Vasculitis

United States, Italy, Netherlands, Poland, Spain, United Kingdom, Germany, Sweden
University of North Carolina, Chapel Hill
National Institutes of Health (NIH); National Center for Research Resources... and other collaborators

Completed

Rare Genetic Disorders of the Breathing Airways

Cystic Fibrosis | Primary Ciliary Dyskinesia | Kartagener Syndrome | Pseudohypoaldosteronism

United States, Canada
University of Vermont
University of Massachusetts, Worcester; Arizona State University; Case Western... and other collaborators

Active, not recruiting

Integrating Behavioral Health and Primary Care for Comorbid Behavioral and Medical Problems (IBHPC)

Depression | Heart Failure | Hypertension | Diabetes | Arthritis | Chronic Pain | Irritable Bowel Syndrome | Insomnia | Asthma | Fibromyalgia | Anxiety | Substance Use Disorder | Chronic Obstructive Lung Disease | Problem Drinking

United States
University of California, San Francisco

Completed

Davunetide (AL-108) in Predicted Tauopathies - Pilot Study

Progressive Supranuclear Palsy | Corticobasal Degeneration Syndrome | Progressive Nonfluent Aphasia | Predicted Tauopathies, Including | Frontotemporal Dementia With Parkinsonism Linked to Chromosome 17

United States
GlaxoSmithKline

Completed

Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD)

Epilepsy | Renal Cell Carcinoma | Hypertension | Diabetes | Restless Legs Syndrome | Pancreatic Cancer | Neuropathic Pain | Chronic Pancreatitis | Renal Cancer | Renal Pelvis Cancer
Institute for Neurodegenerative Disorders

Completed

A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions (FPEB)

Parkinson Disease | Alzheimer Disease | Mild Cognitive Impairment | Fragile X Syndrome | Huntington Disease | Autistic Spectrum Disorders

United States
KU Leuven
Research Foundation Flanders; National Institute for Health and Disability...

Completed

Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care (ERNIE2)

Pneumonia | Sepsis | Abscess | Cellulitis | Meningitis | Osteomyelitis | Complicated Urinary Tract Infection | Bacteraemia | Gastro-enteritis With Dehydration | Viral Respiratory Infection Complicated With Hypoxia

Belgium
National Institute of Neurological Disorders and...

Recruiting

Procedural Motor Memory in Long COVID-19

Ischemic Stroke | Seizure | Infectious Metabolic Encephalopathy | Viral Encephalitis, Small and Large Vessel

United States
Hugo W. Moser Research Institute at Kennedy Krieger...

Recruiting

Home Exercise for Individuals With Neurodegenerative Disease

Neurodegenerative Diseases | Ataxia | Cerebellar Ataxia | Leukodystrophy | Adrenomyeloneuropathy | LBSL | Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation | Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder)

United States
California Pacific Medical Center Research Institute
University of Pittsburgh; Duke University; National Institute on Aging (NIA); University... and other collaborators

Recruiting

Trial of Parkinson's And Zoledronic Acid (TOPAZ)

Parkinson Disease | Osteoporosis | Parkinsonism | Multiple System Atrophy | Progressive Supranuclear Palsy | Parkinson's Disease and Parkinsonism | Dementia With Lewy Bodies | Atypical Parkinsonism | Vascular Parkinsonism

United States
Infectopharm Arzneimittel GmbH
INPADS GmbH; Dr. Oestreich + Partner GmbH

Recruiting

Fosfomycin i.v. for Treatment of Severely Infected Patients (FORTRESS)

Respiratory Tract Infections | Sepsis | Encephalitis | Bacterial Infections | Intraabdominal Infections | Bacteremia | Skin Diseases, Bacterial | Pneumonia, Bacterial | Urinary Tract Infections | Meningitis, Bacterial | Central Nervous System Bacterial Infections | Soft Tissue Infections | Endocarditis, Bacterial | Bone Diseases, Infectious and other conditions

Germany, Austria, Greece, Italy, United Kingdom
Drexel University
Johns Hopkins University; National Institute on Aging (NIA); University of California...

Active, not recruiting

WeCareAdvisor Study for Caregivers of People Living With Dementia

Dementia | Alzheimer Disease | Frontotemporal Dementia | Vascular Dementia | Dementia With Lewy Bodies | Caregiver Stress Syndrome | Caregiver Burnout

United States
Shionogi

Completed

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants

Sepsis | Gram-negative Bacterial Infections | Bloodstream Infections (BSI) | Complicated Intra-abdominal Infection (cIAI) | Hospital Acquired Pneumonia (HAP) | Ventilator-acquired Pneumonia | Complicated Urinary Tract Infection (cUTI)

Spain, Belgium, Latvia, Russian Federation, Estonia, Georgia, Hungary, Thailand, Ukraine
Istanbul University

Unknown

Familial Mediterranean Fever and Behçet: Analysis Before and After Covid19 Pandemic

COVID | FMF | Behcet Disease

Turkey
O'Dorisio, M S
National Cancer Institute (NCI)

Completed

Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors

Sarcoma | Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors | Neuroblastoma | Pheochromocytoma | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United States
Institut National de la Santé Et de la Recherche...
European Union

Completed

Research of Biomarkers in Parkinson Disease (Genepark)

Parkinson Disease | Dystonia | Multiple System Atrophy | Progressive Supranuclear Palsy | Huntington Disease | Diffuse Lewy Body Disease

Slovenia, Germany, Croatia, France
Northwestern University
National Cancer Institute (NCI)

Completed

Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction

Quality of Life | Gastric Cancer | Colorectal Cancer | Small Intestine Cancer | Gastrointestinal Stromal Tumor | Constipation, Impaction, and Bowel Obstruction | Gastrointestinal Carcinoid Tumor

United States
University of Washington
National Cancer Institute (NCI)

Completed

Bendamustine Hydrochloride, Etoposide, Dexamethasone, and Filgrastim For Peripheral Blood Stem Cell Mobilization in Treating Patients With Refractory or Recurrent Lymphoma or Multiple Myeloma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Adam Kittai

Recruiting

Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome

Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Transformed B-Cell Non-Hodgkin Lymphoma | Refractory Transformed Non-Hodgkin Lymphoma | Refractory Transformed B-cell Non-Hodgkin Lymphoma | Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma | Recurrent Transformed... and other conditions

United States
Beth Israel Deaconess Medical Center

Recruiting

Gait Analysis in Neurological Disease

Parkinson's Disease | Parkinsonian Disorders | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Huntington Disease | Atypical Parkinson Disease | Gait, Frontal

United States
Washington University School of Medicine

Active, not recruiting

Congenital Heart Anomaly Risk in Maternal Enteroviral Infection and Diabetes (CHARMED)

Heart Diseases | Virus Diseases | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Diabetes Mellitus, Type 1 | Enterovirus Infections | Pregnancy Complications | Heart Defects, Congenital | Viremia | Congenital Heart Disease | Pregnancy in Diabetic | Enterovirus | Prenatal Infection | Prenatal

United States
Novartis Pharmaceuticals

Available

Managed Access Programs for INC424, Ruxolitinib

Primary Myelofibrosis (PMF) | Polycythemia Vera (PV) | Post Polycythemia Myelofibrosis (PPV MF) | Thrombocythemia Myelofibrosis (PET-MF) | Severe/Very Severe COVID-19 Illness | Steroid Refractory Acute Graft Versus Host Disease (SR aGVHD) | Steroid Refractory Chronic Graft Versus Host Disease...
University of California, San Francisco
National Institutes of Health (NIH); National Institute on Aging (NIA)

Active, not recruiting

4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2 (4RTNI-2)

Progressive Supranuclear Palsy (PSP) | Corticobasal Degeneration (CBD) | Nonfluent Variant Primary Progressive Aphasia (nfvPPA) | Corticobasal Syndrome (CBS) | Cortical-basal Ganglionic Degeneration (CBGD) | Oligosymptomatic/Variant Progressive Supranuclear Palsy (o/vPSP)

United States, Canada
Lebanese University

Completed

Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility (CS-EOSP-ICSI)

Polycystic Ovary Syndrome | Endometriosis | Ectopic Pregnancy | Premature Ovarian Failure | Female Infertility Endocrine | Female Infertility | Fibroids | Salpingitis | Hydrosalpinx | Female Infertility Due to Ovulatory Disorder | Female Infertility of Tubal Origin | Female Infertility Due to Tubal Block | Female... and other conditions

Lebanon
Centre Hospitalier Universitaire Dijon

Unknown

COVID-19 Related Lockdown Effects On Chronic Diseases (CLEO-CD)

Heart Failure | Multiple Sclerosis | Hemophilia | Chronic Respiratory Failure | Horton's Disease | Chronic Coronary Syndrome | AMD and Macular Edema | Malignant Hemopathy

France
University of Bern
Novartis; University Hospital Inselspital, Berne; Schweizerische Multiple Sklerose... and other collaborators

Recruiting

Swiss Pediatric Inflammatory Brain Disease Registry (Swiss-Ped-IBrainD)

Multiple Sclerosis | Optic Neuritis | Neuromyelitis Optica Spectrum Disorder | CNS Sarcoidosis | CNS Vasculitis | Transverse Myelitis | Rasmussen Encephalitis | Acute Disseminated Encephalomyelitis | Anti-NMDAR Encephalitis | Anti-GAD65 Associated Autoimmune Encephalitis | Anti-AMPAR-1/2 Associated Autoimmune... and other conditions

Switzerland
Steno Diabetes Center Greenland
Zealand University Hospital; University of Copenhagen

Recruiting

Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland

Diabetes Mellitus, Type 2 | Diabetic Neuropathies | Diabetic Retinopathy | Obstructive Sleep Apnea | Obesity, Morbid | MODY

Greenland
University Hospital, Essen

Recruiting

HIV-HEART Aging Study (HIVH)

Myocardial Infarction | HIV Infections | Heart Failure | Coronary Disease | Aging | Weight Gain | HIV Encephalopathy

Germany
National Cancer Institute (NCI)

Recruiting

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

Neuroendocrine Tumors | Von Hippel-Lindau Disease | VHL Pancreatic Neuroendocrine Tumors

United States
ANRS, Emerging Infectious Diseases
University Hospital, Geneva; University of Bordeaux; International Agency for... and other collaborators

Recruiting

Evaluation of Triage Options After HPV Testing for Cervical Cancer Screening Among HIV-infected Women (AIMA-CC)

HIV Infections | HPV - Anogenital Human Papilloma Virus Infection

Burkina Faso, Cambodia, Côte D'Ivoire
The Hospital of Vestfold
Oslo University Hospital

Active, not recruiting

Prevention of Coronary Heart Disease in Morbidly Obese Patients (SphCor)

Hypertension | Obstructive Sleep Apnea | Morbid Obesity | Osteoarthrosis | Type 2 DM

Norway
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204) (RICHI)

Chronic Granulomatous Disease | Hemophagocytic Lymphohistiocytosis | Leukocyte Adhesion Deficiency | Chronic Active Epstein-Barr Virus Infection | HIGM-1 | IPEX

United States, Canada
M.D. Anderson Cancer Center

Completed

Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program

Attenuated Familial Adenomatous Polyposis | Deleterious Familial Adenomatous Polyposis

United States
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer

Familial Adenomatous Polyposis | Attenuated Familial Adenomatous Polyposis

United States, Puerto Rico
Neurogene Inc.

Terminated

A Natural History Study of Charcot-Marie-Tooth 4J (CMT4J) (CMT4J)

Charcot-Marie-Tooth Disease | Hereditary Motor and Sensory Neuropathy IV

United States
University Hospital, Angers

Unknown

Pharmacogenetic Study of Antimitotic Therapies Involved in Hepatic VOD in Children With Nephroblastoma or ALL (MVO)

Acute Lymphoblastic Leukemia | Nephroblastoma | Hepatic Veno-Occlusive Disease

France
Tel-Aviv Sourasky Medical Center

Unknown

Turmeric Supplementation on Polyp Number and Size in Patients With Familial Adenomatous Polyposis.

Familial Adenomatous Polyposis | FAP | FAP Gene Mutation
University Health Network, Toronto
The Leukemia and Lymphoma Society

Completed

Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancy

Acute Myeloid Leukemia | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | Hematologic Malignancy | Chronic Myelogenous Leukemia | Myelodysplasia | Hodgkin's Disease

Canada

Clinical Trials on Li-Fraumeniho syndrom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cote d'Ivoire

Conditions

Rare Diseases

Drug Interventions

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