Clinical Trials on Lipid Metabolism Disorders in Switzerland

Total 2827 results

Center for Primary Care and Public Health (Unisante)...
Swiss Heart Foundation

Completed

Cascade Genetic Testing of Familial Hypercholesterolemia (CATCH)

Familial Hypercholesterolemia

Switzerland
Novartis

Completed

Efficacy and Safety of Fluvastatin in Children With Heterozygous Familial Hypercholesterolemia

Mixed Dyslipidemia | Heterozygous Familial Hypercholesterolemia

Switzerland
Novartis

Completed

Efficacy of Fluvastatin and Fenofibrate in Comparison to Simvastatin and Ezetimibe in Patients With Metabolic Syndrome

Dyslipidemia

Germany, Switzerland
University Hospital, Basel, Switzerland

Completed

Effects of FXR Activation on Hepatic Lipid and Glucose Metabolism

Metabolic Syndrome | Familial Combined Hyperlipidemia | Familial Hypertriglyceridemia

Switzerland
University of Lausanne
University Hospital Inselspital, Berne; Centre Hospitalier Universitaire Vaudois

Completed

Reduction of Sweetened Beverages and Intrahepatic Fat (REDUCS)

Obesity | Metabolic Syndrome | Dyslipidemia

Switzerland
Centre Hospitalier Universitaire Vaudois
Agroscope Liebefeld-Posieux Research Station ALP

Completed

Effects of a Probiotics on the Health of Normal Young Males (FFF)

Inflammation | Dyslipidemia

Switzerland
University of Zurich

Completed

Pulmonary Involvement in Patients With Fabry Disease

Fabry Disease

Switzerland
University of Basel
University of Lausanne; Technical University of Munich

Recruiting

Reducing Circulating Sphingolipid Levels to Optimise Cardiometabolic Health - The SphingoFIT Trial (SphingoFIT)

Cardiovascular Diseases | Dyslipidemias | Blood Pressure | Overweight and Obesity | Metabolic Disease

Switzerland
Novartis

Completed

A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension and Hypercholesterolemia

Hypercholesterolemia | Essential Hypertension

Switzerland, Germany
University of Lausanne

Completed

Acute Effect of Fructose on Lipid Metabolism and Gender Differences

Lipid Metabolism

Switzerland
University Hospital Inselspital, Berne
Takeda

Completed

Physiologic Plasticity of Intramyocardial Lipid Storage

Lipid Metabolism

Switzerland
University of Zurich

Completed

Sleepiness and Sleep-disordered Breathing in Fabry Disease. A Prospective Cohort Study.

Fabry Disease

Switzerland
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Swiss Study With Atorvastatin in Hyperlipidemic Patients Measuring LDL-Cholesterol (ACTFAST SWISS)

Hyperlipidemia

Switzerland
Albina Nowak, MD
Swiss National Science Foundation

Recruiting

Effect of Cannabinoids on Pain in Fabry Disease Patients

Pain, Neuropathic

Switzerland
University of Lausanne Hospitals
Salk Institute for Biological Studies

Completed

Study of Eating Patterns With a Smartphone App and the Effects of Time Restricted Feeding in the Metabolic Syndrome

Obesity | Metabolic Syndrome | Dyslipidemias | Glucose Intolerance | Eating Behavior | Steatosis of Liver

Switzerland
Spital Linth
University of Zurich; National University, Singapore

Unknown

Lipidomics and Functional Analyses of Platelets in Fabry Disease

Fabry Disease

Switzerland
Clarunis - Universitäres Bauchzentrum Basel

Recruiting

Different Limb Lengths in Gastric Bypass Surgery (SLIM)

Hypertension | Diabetes Mellitus, Type 2 | Dyslipidemias | Sleep Apnea | Obesity, Morbid

Switzerland
Sanofi

Terminated

European Trial About Effect of RimoNabant on Abdominal Obese Patients With dysLipidemia (ETERNAL)

Obesity | Dyslipidemias

Germany, Netherlands, Turkey, Slovakia, United Kingdom, Finland, Hungary, Ireland, Italy, Norway, Greece, Sweden, Czech Republic, Portugal, Switzerland
Amgen

Completed

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2 (GAUSS-2)

Hyperlipidemia

United States, Denmark, Belgium, Germany, Hong Kong, Netherlands, France, Australia, Canada, South Africa, United Kingdom, Spain, Poland, Switzerland
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Atorvastatin Three Year Pediatric Study

Familial Hypercholesterolemia

United States, Spain, Turkey, Canada, Belgium, Germany, Greece, Hungary, Italy, Norway, Poland, Puerto Rico, Russian Federation, Slovakia, Switzerland
Kantonsspital Baden

Completed

Cold Induced Futile Cycles In White Adipose Tissue (Metabol)

Metabolism Disorder

Switzerland
University of Ulm
University of Pisa; IRCCS Azienda Ospedaliero-Universitaria di Bologna; Medical... and other collaborators

Recruiting

Registry for Patients With Lipodystrophy (ECLip Registry)

Lipodystrophy Acquired | Lipodystrophy Congenital

Austria, France, Germany, Hungary, Italy, Portugal, Spain, Netherlands, Russian Federation, Slovenia, Switzerland, Turkey, United Kingdom
Amgen

Terminated

Study to Evaluate the Safety of Repatha® in Pregnancy

Pregnancy | Hypercholesterolaemia

Belgium, Denmark, Italy, Czechia, United Kingdom, Australia, Austria, Greece, Switzerland, Netherlands, Spain, Sweden, Slovakia, Norway
Amgen

Completed

Reduction of LDL-C With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study-2 (RUTHERFORD-2)

Hyperlipidemia

Canada, France, Netherlands, United Kingdom, New Zealand, South Africa, Spain, United States, Australia, Germany, Sweden, Hong Kong, Switzerland, Norway
Sanofi
Regeneron Pharmaceuticals

Completed

Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)

Hypercholesterolemia

France, Belgium, Austria, Canada, Czechia, Denmark, Finland, Germany, Greece, Hungary, Poland, Romania, Slovakia, Slovenia, Spain, Switzerland
Novartis Pharmaceuticals

Recruiting

Study Evaluating Effectiveness and Adherence of Inclisiran Plus Standard of Care (SoC) Lipid-lowering Therapy Compared to SoC in ASCVD (VICTORION REAL)

Mixed Dyslipidemia | Primary Hypercholesterolemia

Switzerland, Saudi Arabia, United Arab Emirates, United Kingdom, Austria, Israel, China, Malaysia
Amgen

Completed

Open-label Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Hypercholesterolemia

Canada, Netherlands, Spain, Belgium, United States, Russian Federation, Czechia, Mexico, Korea, Republic of, Australia, United Kingdom, Argentina, Israel, France, Hungary, Germany, Greece, Poland, Switzerland, Italy, Brazil, Sweden, Norwa... and more
Amgen

Completed

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia) (HAUSER-OLE)

Familial Hypercholesterolemia

Canada, Italy, Norway, Belgium, United States, Turkey, Australia, Austria, South Africa, Poland, Switzerland, Spain, Portugal, Slovenia, Brazil, Russian Federation, Hungary, United Kingdom, Colombia, Czechia, Netherlands, Greece, Ma...
Amgen

Completed

LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2 (LAPLACE-2)

Hyperlipidemia

United States, Denmark, France, Italy, Czechia, Taiwan, Switzerland, Korea, Republic of, Germany, Hong Kong, Netherlands, Australia, Belgium, Canada, Hungary, South Africa, Russian Federation, Spain, United Kingdom, Sweden, Mexico
Sanofi

Completed

Obese Patients With Untreated Dyslipidemias (RIO-Lipids)

Obesity | Dyslipidemia

United States, Canada, Australia, Italy, Spain, Sweden, Switzerland, Finland
Amgen

Completed

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER)

Dyslipidemia

United States, Austria, Belgium, Canada, Denmark, Finland, France, Germany, Italy, Netherlands, Spain, Sweden, United Kingdom, Czechia, Hungary, Taiwan, Colombia, Poland, Russian Federation, Switzerland, Korea, Republic of, Mexico, ... and more
Amgen

Completed

GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound (GLAGOV)

Hypercholesterolemia

United States, Canada, Denmark, Germany, Italy, Netherlands, Spain, Sweden, Belgium, Taiwan, Russian Federation, France, Czechia, Mexico, Korea, Republic of, Australia, United Kingdom, Argentina, Israel, Hungary, South Africa, Greece and more
Alexion Pharmaceuticals

Completed

An Observational Study of Patients With Lysosomal Acid Lipase Deficiency/Cholesteryl Ester Storage Disease Phenotype

Lysosomal Acid Lipase Deficiency | Cholesterol Ester Storage Disease(CESD)

United States, United Kingdom, France, Canada, Czech Republic, Italy, Poland, Switzerland
University of Zurich

Active, not recruiting

Effects of Treatments for Anemia and Iron Deficiency on the Electrolyte Balance in Lung Transplant Recipients: A Special Focus on Hypophosphatemia

Hypophosphatemia

Switzerland
Foundation for Cardiovascular Research, Zurich
Bristol-Myers Squibb

Completed

Effect of Atazanavir on Endothelial Function in HIV-Infected Patients (ENDOPACT)

HIV Infections | Dyslipidemia

Switzerland
Amgen

Completed

Chart Review of Repatha® in Subjects With Hyperlipidaemia (HEYMANS)

Hypercholesterolaemia

Austria, Italy, Belgium, Czechia, Switzerland, Spain, Slovakia, Germany, Portugal, Greece, Bulgaria, Sweden
Novartis Pharmaceuticals

Active, not recruiting

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia (ORION-16)

Familial Hypercholesterolemia - Heterozygous

United States, Germany, South Africa, Greece, Italy, Czechia, Taiwan, Slovakia, Turkey, France, Russian Federation, Canada, Spain, Jordan, Switzerland, Hungary, Poland, Netherlands, Norway, United Kingdom, Lebanon, Argentina, Brazil, ... and more
Amgen

Completed

Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders (HAUSER-RCT)

Heterozygous Familial Hypercholesterolemia

United States, Canada, Italy, Norway, Belgium, Turkey, Australia, New Zealand, Austria, Czechia, South Africa, Poland, Spain, Switzerland, Netherlands, Taiwan, Finland, Brazil, Portugal, Slovenia, Russian Federation, Hungary, United... and more
Novartis Pharmaceuticals

Recruiting

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Adolescent ORION-16 or ORION-13 Studies (V-PEDS-OLE)

Heterozygous or Homozygous Familial Hypercholesterolemia

Netherlands, Israel, Hungary, Italy, Germany, Turkey, Spain, United States, France, Norway, Russian Federation, South Africa, United Kingdom, Canada, Switzerland, Brazil, Lebanon, Slovenia, Poland, Taiwan, Malaysia
Prof Gérard WAEBER
Centre Hospitalier Universitaire Vaudois; University of Lausanne; Center for...

Terminated

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis. (DIAFER)

Iron-deficiency | Safety Issues | Metabolic Disorder, Glucose | Iron Toxicity | Glucose Metabolism Disorders (Including Diabetes Mellitus) | Metabolic Side Effects of Drugs

Switzerland
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)

Dyslipidemia

United States, Australia, Brazil, Finland, Germany, Israel, Italy, Kuwait, Lebanon, Norway, Sweden, Switzerland, Turkey, United Arab Emirates, United Kingdom
University Hospital Inselspital, Berne

Terminated

The Influence of Different Hydrocortisone Replacement Doses on the Partitioning and Flexibility of Ectopic Lipids in Patients With Corticotropic Hypopituitarism (Hydrocort)

Hypopituitarism | Insulin Sensitivity | Hydrocortisone | Lipids | Fatty Acids, Nonesterified

Switzerland
Emma Marie Caroline Slack
University Children's Hospital

Completed

Characterization of Intestinal Microbiota in Children With Inborn Errors of Metabolism (IEM) (IEM)

Inborn Errors of Metabolism | Propionic Aciduria | Methylmalonic Aciduria | Urea Cycle Disorder

Switzerland
University Hospital Inselspital, Berne
Erasmus Medical Center

Completed

Understanding Hypoglycaemia After Bariatric Surgery (HYPOBAR1)

Bariatric Surgery

Switzerland
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab Versus Placebo on Top of Maximally Tolerated Lipid Lowering Therapy in Patients With Hypercholesterolemia Who Have Type 1 or Type 2 Diabetes and Are Treated With Insulin (ODYSSEY DM - Insulin)

Hypercholesterolaemia

Belgium, Spain, Germany, Austria, Italy, United States, France, Netherlands, Switzerland, United Kingdom
University Hospital, Geneva

Completed

Newborn Phosphocalcic Metabolism After Intravenous Iron Administration During Pregnancy

Iron Induced Hypophosphatemia

Switzerland
University Hospital Inselspital, Berne
Swiss National Science Foundation

Completed

The Effect of Dietary Fat Load and Physical Exercise on the Flexibility and Partitioning of Ectopic Lipids.

Growth Hormone Deficiency | Insulin Sensitivity | Aerobic Exercise | Ectopic Lipids | Fat Load

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Canakinumab for the Treatment of Postprandial Hypoglycemia (CanpHy)

Postprandial Hypoglycemia

Switzerland
Donat R. Spahn
University of Zurich

Completed

Ferric Carboxymaltose With or Without Phosphate Substitution for the Treatment of Iron Deficiency or Iron Deficiency Anemia

Iron-deficiency | Anemia | Hypophosphatemia

Switzerland
Afimmune

Terminated

Assess Efficacy and Safety of Epeleuton in Patients With Hypertriglyceridemia and Type 2 Diabetes (TRIAGE)

Type 2 Diabetes | Hypertriglyceridemia

Georgia, United States, Germany, Israel, Latvia, Switzerland

Clinical Trials on Lipid Metabolism Disorders in Switzerland

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