Clinical Trials on Lipider

Total 3828 results

Catabasis Pharmaceuticals

Completed

A 2-Part, Phase 1, Single and Multiple Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of CAT-2054 in Healthy Subjects

Hypercholesterolemia

United States
AstraZeneca
Parexel

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD8233 in Healthy Male Subjects With Increased Elevated LDL-C Levels.

Hypercholesterolemia

United States
AB Biotics, SA
University of Extremadura

Completed

Combination of AB-LIFE Probiotic Plus Monacolin K to Reduce Blood Cholesterol

Hypercholesterolemia
Azienda di Servizi alla Persona di Pavia

Completed

Artichoke and Bergamot Phytosome

Hypercholesterolemia

Italy
Regeneron Pharmaceuticals
Sanofi

Terminated

Praluent® (Alirocumab) Pregnancy Exposure Registry: An OTIS Pregnancy Surveillance Study

Hypercholesterolemia

United States
Chung Shan Medical University

Unknown

Effect of InnoSlim® on Blood Sugar and Blood Lipids Regulation in Humans

Hyperlipidemia

Taiwan
Chong Kun Dang Pharmaceutical

Completed

Clinical Trial to to Compare of the Efficacy and Safety of Lipilou® 20 mg and Lipilou® 10 mg

Hypercholesterolemia

Korea, Republic of
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) in Patients With Primary Hypercholesterolemia and Moderate, High, or Very High Cardiovascular (CV) Risk, Who Are Intolerant to Statins (ODYSSEY ALTERNATIVE)

Hypercholesterolemia

United States, France, Italy, Israel, United Kingdom, Austria, Canada, Norway
Merck Sharp & Dohme LLC

Completed

A Study of the Safety and Efficacy of Anacetrapib (MK-0859) Among Participants With Hypercholesterolemia When Added to Ongoing Statin Therapy (MK-0859-022)

Hypercholesterolemia
NeuroBo Pharmaceuticals Inc.

Completed

Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients as Monotherapy or in Combination With Atorvastatin

Hypercholesterolemia
NeuroBo Pharmaceuticals Inc.

Completed

Pharmacokinetics and Pharmacodynamics Study of Gemcabene in Healthy Volunteers

Hypercholesterolemia
NeuroBo Pharmaceuticals Inc.

Completed

Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients on Stable Statin Therapy

Hypercholesterolemia
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg When Added to PCSK9 Inhibitor Therapy

Hypercholesterolemia

United States
University Health Network, Toronto

Completed

L-NMMA on GLP-2 Mediated Intestinal Lipoprotein Release (LNMMA)

Hyperlipidemias

Canada
Montreal Heart Institute
Institut de Recherches Cliniques de Montreal; Royal Victoria Hospital, Canada; Queen Elizabeth II Health Sciences Centre and other collaborators

Completed

A Study to Evaluate the Lipid Regulating Effects of 1-Methylnicotinamide (1-MNA)

Hypertriglyceridemia

Canada
Quadram Institute Bioscience

Completed

Bilberry Fruit and Black Rice Derived Anthocyanins on Lipid Status

Hyperlipidemia

United Kingdom
Chang Gung Memorial Hospital

Completed

Myocardial Lipid and Creatine of Heart Failure on MRS

Myocardial Lipid

Taiwan
AstraZeneca

Completed

Epanova® for Lowering Very High Triglycerides II (EVOLVE II) (EVOLVEII)

Hypertriglyceridemia

Denmark, United States, Hungary, Netherlands, Russian Federation, Czechia, Canada
Takeda

Completed

Evaluation of the Safety and Efficacy of Long-term Use of Omega-3 Fatty Acid Ethyl Esters

Hyperlipidemia

Japan
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Administering Multiple Oral Doses of GSK1292263 Alone and With Atorvastatin

Dyslipidemias | Dyslipidaemias

United States
Pfizer

Completed

Pharmacokinetics And Relative Bioavailability Of Bococizumab (PF-04950615; RN316) When Administered To The Abdomen, Thigh Or Upper Arm

Hypercholesterolemia

United States
Esperion Therapeutics, Inc.

Completed

A Study Of Pharmacokinetics, Pharmacodynamics And Safety Of Adding ETC-1002 To Atorvastatin 80 mg

Hyperlipidemia

United States
Amgen

Completed

Open-label Extension (OLE) Study to Assess Safety and Efficacy of Evolocumab

Hypercholesterolemia

Canada, Netherlands, Spain, Belgium, United States, Russian Federation, Czechia, Mexico, Korea, Republic of, Australia, United Kingdom, Argentina, Israel, France, Hungary, Germany, Greece, Poland, Switzerland, Italy, Brazil, Sweden, Norwa... and more
Esperion Therapeutics, Inc.

Completed

Single Radiolabeled Dose Study to Investigate the Absorption, Metabolism and Excretion of [14C]-ETC-1002

Hyperlipidemia

United Kingdom
University of California, Los Angeles

Terminated

Effects of a Supplement Derived From Palm Oil on Cholesterol Levels in the Blood (TRF)

Hypercholesterolemia

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab in Patients With Hypercholesterolemia Not Adequately Controlled With Non-statin Lipid Modifying Therapy or the Lowest Strength of Statin (ODYSSEY-NIPPON)

Hypercholesterolemia

Japan
Merck Sharp & Dohme LLC

Completed

A Study of MK-6213 Co-Administered With Atorvastatin in Participants With Hypercholesterolemia (MK-6213-006)

Hypercholesterolemia
Eli Lilly and Company

Terminated

A Study of Evacetrapib (LY2484595) in Combination With Atorvastatin in Japanese Participants With Primary Hypercholesterolemia

Hypercholesterolemia

Japan
B. Braun Medical Inc.

Completed

(H.E.L.P.)Apheresis Therapy to Compare the Reduction of LDL (Low Density Lipoprotein) Cholesterol (FUTURA)

Hypercholesterolemia

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Phase III Study To Evaluate Alirocumab in Patients With Hypercholesterolemia Not Treated With a Statin (ODYSSEY CHOICE II)

Hypercholesterolemia

United States, Australia, Belgium, Canada, Denmark, Netherlands, New Zealand, Spain
IlDong Pharmaceutical Co Ltd

Completed

A Clinical Trial to Compare the Efficacy and Safety of a Combination Therapy of Ezetimibe and Rosuvastatin Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients (I-ROSETTE Study) (I-ROSETTE)

Hypercholesterolemia

Korea, Republic of
Hospital General Universitario Gregorio Marañon

Completed

Evolocumab Versus LDL Apheresis in Patients With Hypercholesterolemia

Hypercholesterolemia

Spain
IRCCS Policlinico S. Matteo
University of Pavia

Completed

Berberine, Chlorogenic Acid and Tocotrienols in Menopause-associated Dyslipidemia

Dyslipidemia

Italy
Sanofi
Regeneron Pharmaceuticals

Completed

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous (SC) Administered Alirocumab in Healthy Chinese Subjects

Hypercholesterolemia

China
Hanyang University

Completed

Effect of Intake of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on Blood Cholesterol.

Hyperlipidemia

Korea, Republic of
Affiris AG
Medical University of Vienna

Completed

Study Assessing Safety, Immunogenicity and LDLc -Lowering Activity of 2 PCSK9 Targeting AFFITOPE Vaccines in Healthy Subjects (AFF012)

Hypercholesterolemia

Austria
Shin Poong Pharmaceutical Co. Ltd.

Completed

The Efficacy and Safety of Combination Therapy of Rosuvastatin and Ezetimibe and Rosuvastatin Monotherapy in Patients With Primary Hypercholesterolemia

Hypercholesterolemia

Korea, Republic of
University of Reading
Medical Research Council

Completed

Replacement of Saturated Fat in Dairy on Total Cholesterol (RESET)

Hypercholesterolemia

United Kingdom
University of Manitoba

Completed

Genetic Basis for Heterogeneity in Response of Plasma Lipids to Plant Sterols

Hyperlipidemia

United States, Canada
Clinical Research Center for End Stage Renal Disease...
Ministry of Health & Welfare, Korea

Completed

The Effects of Lowering Low-density Lipoprotein Cholesterol Levels to New Targets on Cardiovascular Complications in Peritoneal Dialysis Patients

Hypercholesterolemia

Korea, Republic of
Johns Hopkins University

Terminated

Supplementation With Omega-3: Mechanism of Action (SOMA)

Hypertriglyceridemia

United States
University Health Network, Toronto
Merck Frosst Canada Ltd.

Completed

Sitagliptin Regulation of Intestinal and Hepatic Lipoprotein Particle and Hepatic Glucose Production in Humans

Hyperlipidemia

Canada
Hanmi Pharmaceutical Company Limited

Completed

Pharmacokinetics and Safety of HCP1105 and Co-administration of HGP0918, HGP0816 in Healthy Male Volunteers

Hyperlipidemias

Korea, Republic of
Durham VA Medical Center

Completed

Cholesterol Medication Packaging Study (MWV_CAPS)

Hypercholesterolemia

United States
Sanofi

Terminated

Evaluation of Safety and Efficacy of AVE5530 as add-on to Ongoing High Doses of Statins in Patients With Primary Severe Hypercholesterolemia

Hypercholesterolemia

United States, France, Canada, Russian Federation, Ukraine, Netherlands, Bulgaria, Belgium, Czech Republic, Israel, Slovakia, Australia, South Africa
USDA Beltsville Human Nutrition Research Center

Completed

A Comparison of the Effects on Cardiovascular Risk Factors of Korean and American Dietary Profiles

Hypercholesterolemia

United States
University of Utah
GlaxoSmithKline

Withdrawn

Effects of Lovaza on High Density Lipoprotein (HDL) Composition and Function in Hypertriglyceridemia

Hypertriglyceridemia

United States
Yonsei University

Completed

Effects of α-linolenic Acid Supplementation on Hemostasis in Nondiabetic and Hypercholesterolemic Subjects

Hypercholesterolemia

Korea, Republic of
Sanofi
Regeneron Pharmaceuticals

Completed

Long-term Safety and Tolerability of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY Long Term)

Hypercholesterolemia

Sweden, Germany, Russian Federation, Denmark, Israel, South Africa, Spain, Hungary, United States, Colombia, Czech Republic, Argentina, Belgium, Bulgaria, Canada, Chile, Finland, France, Italy, Mexico, Netherlands, Norway, Poland, Por... and more
Alnylam Pharmaceuticals
The Medicines Company

Completed

A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

Hypercholesterolemia

United Kingdom

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