Clinical Trials on Lipodystrophy-Syndrome

Total 33837 results

Baylor College of Medicine

Completed

Leptin for Abnormal Lipid Kinetics in HIV Lipodystrophy Syndrome

HIV Lipodystrophy

United States
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Energy Expenditure of People Living With HIV/AIDS

HIV/AIDS | HIV Lipodystrophy Syndrome
ViiV Healthcare
GlaxoSmithKline

Completed

An Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK1265744 Administered as a Single Oral Dose and a Study to Describe the Pharmacokinetics of a Supratherapeutic Dose of GSK1265744 in Healthy Adult Subjects

HIV-associated Lipodystrophy Syndrome

United States
French National Agency for Research on AIDS and...

Terminated

Study Evaluating the Impact on Fat Distribution of Nucleoside Reverse Transcriptase Inhibitor (NRTI)-Sparing Regimens in Antiretroviral Experienced Patients With Lipoatrophy

HIV Infections | HIV Lipodystrophy Syndrome

France
Hannover Medical School
Hector-Stiftung

Completed

Role of the Autonomic Nervous System in HIV-Lipodystrophy

HIV Infections | Lipodystrophy-Syndrome

Germany
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

A Study of Physical and Metabolic Abnormalities in HIV Infected and Uninfected Children and Youth

HIV Infections | Dyslipidemia | Osteoporosis | Osteopenia | Lipodystrophy | HIV-Associated Lipodystrophy Syndrome | HIV Lipodystrophy Syndrome

United States, Puerto Rico
University of Novi Sad
Merck Sharp & Dohme LLC

Recruiting

Neuroinflammation and Neurodegeneration in HIV-positive Subjects Switched and Initially Treated With INSTI

Metabolic Syndrome | Aging | HIV I Infection | HIV Associated Lipodystrophy

Serbia
Washington University School of Medicine
National Center for Complementary and Integrative Health (NCCIH)

Completed

Yoga for the Management of HIV-Metabolic Syndromes

HIV Infections | Hypertension | HIV Lipodystrophy | HIV Metabolic Cardiovascular Syndrome | HIV Metabolic Syndromes

United States
Columbia University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Body Composition and Adipose Tissue in HIV

Body Composition | Growth Hormone Deficiency | HIV Lipodystrophy Syndrome

United States
Beth Israel Deaconess Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); A...

Completed

Randomized, Placebo-Controlled Study of Leptin for the Treatment of HIV Lipodystrophy and Metabolic Syndrome

HAART-induced Lipodystrophy and Metabolic Syndrome

United States
Danish HIV Research Group
Odense University Hospital; Aarhus University Hospital; Rigshospitalet, Denmark; Hvidovre University Hospital

Completed

Switching From Zidovudine to an NNRTI or Lopinavir/Ritonavir in Patients Treated With Zidovudine/ Lamivudine/Abacavir.

HIV | Hypercholesterolemia | Lipoatrophy | HIV Associated Lipodystrophy Syndrome.

Denmark
Kirby Institute
Bristol-Myers Squibb; GlaxoSmithKline; Merck Sharp & Dohme LLC; Gilead Sciences; Hoffmann-La... and other collaborators

Terminated

Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy

HIV Infections | HIV-Associated Lipodystrophy

Australia
Universidade Federal do Rio Grande do Norte

Completed

Detraining in People Living With HIV/AIDS (PVHA)

Sarcopenia | Lipodystrophy Syndrome, HIV

Brazil
Bristol-Myers Squibb

Completed

Study of Reyataz in HIV-infected Patients With Lipodystrophy Syndrome

HIV-Associated Lipodystrophy Syndrome

Spain, Italy, United States, Canada, France, Mexico, United Kingdom, Poland, Germany
Aegerion Pharmaceuticals, Inc.

Recruiting

MEASuRE: Metreleptin Effectiveness And Safety Registry (MEASuRE)

Partial Lipodystrophy | Generalised Lipodystrophy

United States, Germany, Italy
University Hospital, Lille

Recruiting

Study of Cortisol Metabolism in Familial Partial Lipodystrophy Type 2 (LIPOCORT)

Familial Partial Lipodystrophy Type 2

France
French National Agency for Research on AIDS and...

Terminated

Evaluation of the Occurrence of Lipoatrophy in HIV-1 Infected Naive Patients

HIV Infections | HIV-Associated Lipodystrophy Syndrome

France
French National Agency for Research on AIDS and...
Sanofi; Procitech

Completed

Safety and Efficacy of Intradermal Injections of Newfill Versus Eutrophill in the Treatment of Facial Lipoatrophy in HIV-infected Patients ANRS 132 SMILE

HIV-Associated Lipodystrophy Syndrome

France
French National Agency for Research on AIDS and...
Takeda

Terminated

Effect of Pioglitazone on HIV-1 Related Lipoatrophy: a Randomized, Double Blind, Placebo-Controlled Trial in 130 Patients

HIV Infections | HIV-Associated Lipodystrophy Syndrome

France
Beth Israel Deaconess Medical Center
American Diabetes Association

Completed

Combination of Insulin Sensitizer and Leptin as Treatment for the HAART -Induced Metabolic Syndrome

HIV Lipodystrophy

United States
National Institute of Diabetes and Digestive and...

Completed

Myocardial Function & FFA Metabolism in HIV Metabolic Syndrome (WU197)

HIV Infections | Cardiovascular Disease | Insulin Resistance | HIV Lipodystrophy | The Metabolic Syndrome

United States
Weill Medical College of Cornell University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Growth Hormone and/or Rosiglitazone for HIV-Associated Increased Abdominal Fat and Insulin Resistance

HIV Infections | Insulin Resistance | Body Weight Changes | Metabolic Syndrome X | HIV-Associated Lipodystrophy Syndrome

United States
Amryt Pharma

Recruiting

Study to Evaluate the Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects With PL (METRE-PL)

Partial Lipodystrophy

United States, Canada
Centre Hospitalier Universitaire de la Réunion

Recruiting

Impact of Lipodystrophy on the Inflammatory State of Non-diabetic Dunnigan Reunion Island Subjects (LIPOKINES)

Lipodystrophy | Dunnigan Syndrome

Réunion
Regeneron Pharmaceuticals

Available

Expanded Access to REGN4461 for Patients With Lipodystrophy or Monogenic Obesity With Complications of Leptin Deficiency or Deficient Leptin Signaling

Partial Lipodystrophy | Generalized Lipodystrophy | Monogenic Obesity Due to LEP or LEPR Loss of Function
University of Ulm
University of Pisa; IRCCS Azienda Ospedaliero-Universitaria di Bologna; Medical... and other collaborators

Recruiting

Registry for Patients With Lipodystrophy (ECLip Registry)

Lipodystrophy Acquired | Lipodystrophy Congenital

Austria, France, Germany, Hungary, Italy, Portugal, Spain, Netherlands, Russian Federation, Slovenia, Switzerland, Turkey, United Kingdom
NHS Lothian

Completed

Psychological Morbidity and Facial Volume in HIV Lipodystrophy: Quantification of Treatment Outcome

HIV-Associated Lipodystrophy Syndrome
Hospital Clinic of Barcelona

Completed

Strategies of Interruption/Reinitiation of Antiretroviral Therapy in HIV-Infected Patients With Lipodystrophy

HIV-Associated Lipodystrophy Syndrome

Spain
Amsterdam UMC, location VUmc
Boehringer Ingelheim; Abbott

Unknown

MEDICLAS Study (Metabolic Effects of Different Classes of AntiretroviralS)

HIV Infections | HIV-Associated Lipodystrophy Syndrome

Finland, Netherlands, Spain, United Kingdom
Danish HIV Research Group
Odense University Hospital; Aarhus University Hospital; Rigshospitalet, Denmark; Hvidovre University Hospital and other collaborators

Unknown

Comparing a Nucleoside-Analogue-Sparing Regimen and a Protease-Inhibitor-Sparing Regimen in HIV Infected Patients

HIV-Associated Lipodystrophy Syndrome

Denmark
University of Texas Southwestern Medical Center

Completed

Trial of Leptin Replacement Therapy in Patients With Lipodystrophy

Insulin Resistance | Partial Lipodystrophy | Generalized Lipodystrophy | Hypoleptinemia

United States
Regeneron Pharmaceuticals

Active, not recruiting

Study of REGN4461, a Leptin Receptor Agonist Antibody, in Patients With Generalized Lipodystrophy

Generalized Lipodystrophy

United States, Peru, Russian Federation, Turkey
Mayo Clinic

Completed

Familial Partial Lipodystrophy Study (FPL)

Lipodystrophy, Familial Partial

United States
Escola Superior de Tecnologia da Saúde do Porto

Completed

Shockwave Therapy (SWT) (SWT)

Gynoid Lipodystrophy

Portugal
University of Texas Southwestern Medical Center

Terminated

Effects of IGF-I in HIV Metabolic Disease

HIV Lipodystrophy

United States
Eli Lilly and Company

Active, not recruiting

A Study of Baricitinib (LY3009104) in Adult and Pediatric Japanese Participants With NNS/CANDLE, SAVI, and AGS

Aicardi Goutieres Syndrome | Nakajo-Nishimura Syndrome | Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature Syndrome | STING-Associated Vasculopathy With Onset in Infancy

Japan
Hvidovre University Hospital

Unknown

Follow-up on the HIGH: Low Study - the Longterm Effects of Growth Hormone

HIV Infections | HIV-Associated Lipodystrophy Syndrome

Denmark
Akcea Therapeutics
Ionis Pharmaceuticals, Inc.

Terminated

The BROADEN Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Partial Lipodystrophy

Familial Partial Lipodystrophy

United States, Netherlands, Belgium, Brazil, Canada, Germany, Russian Federation
University of Michigan

Available

Expanded Access Metreleptin Study

Familial Partial Lipodystrophy

United States
Assiut University

Unknown

Different Surgical Modalities for Thigh Lipodystrophy Including Liposuction,Thigh Lift and Liposuction Assisted Thigh Lift (thigh lift)

Thigh Lipodystrophy

Egypt
National Institutes of Health Clinical Center (CC)

Terminated

Comparing Magnetic Resonance Imaging/Spectroscopy Techniques

Tumors | Abdominal Organs - Lipodystrophy

United States
Theratechnologies
Vanderbilt University Medical Center; Medpace, Inc.; Dacima Consulting; Echosens

Completed

The Visceral Adiposity Measurement and Observation Study (VAMOS)

Liver Diseases | BMI | Liver Fat | HIV | NAFLD | Hepatic Fibrosis | Hepatic Steatosis | HIV-1-infection | Liver Fibrosis | NASH | HIV Lipodystrophy | HIV-Associated Lipodystrophy | HIV I Infection | Waist Circumference | HIV Infection Primary | HIV Disease Progression | HIV-Infections | Lipohypertrophy | Ectopic Fat

United States
Assistance Publique - Hôpitaux de Paris

Completed

Polyacrylamide Hydrogel Injection in HIV-related Lipoatrophy (LIPOPHILL)

HIV Infection | Antiretroviral Side Effects | Lipodystrophy Syndrome Related to HIV Infection

France
Aegerion Pharmaceuticals, Inc.

Active, not recruiting

Immunogenicity of Metreleptin in Patients With Generalized Lipodystrophy

Generalized Lipodystrophy

United States
National Institute of Diabetes and Digestive and...

Recruiting

Feasibility of Adipose Tissue Triglyceride (TG) Labelling in Familial Partial Lipodystrophy (FPLD)

Lipodystrophy

United States
Abhimanyu Garg

Completed

Phase 2 Study of Obeticholic Acid for Lipodystrophy Patients

Familial Partial Lipodystrophy

United States
Massachusetts General Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Effects of Short-term Growth Hormone in HIV-infected Patients

HIV Lipodystrophy

United States
Medical University of South Carolina

Completed

Immune Response to Pneumococcal Vaccination in Aging HIV Positive Adults

Aging | HIV Lipodystrophy

United States
Massachusetts General Hospital

Completed

Effects of Growth Hormone Releasing Hormone in HIV

HIV | HIV Lipodystrophy

United States
Kirby Institute
National Heart, Lung, and Blood Institute (NHLBI); St Vincent's Hospital, Sydney

Completed

HIV Infection And Metabolic Abnormalities Protocol 1 (HAMA001)

Cardiovascular Disease | HIV-Associated Lipodystrophy Syndrome

Australia

Clinical Trials on Lipodystrophy-Syndrome

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