Clinical Trials on Livedo Vasculitis in Czechia

Total 153 results

Nordic Pharma SAS

Terminated

Clinical Study Comparing the New Immunosuppressive Drug Gusperimus With the Conventional Treatment in Wegener's Granulomatosis (SPARROW)

Wegeners Granulomatosis

Czech Republic
University Hospital Ostrava

Recruiting

Evaluation of Tissue Glue on PICC and Midline Catheters Insertion Sites

Adult Patients With Mid-term or Long-term Venous Access

Czechia
Nippon Kayaku Co., Ltd.

Completed

Phase II Study on Gusperimus in Patients With Refractory Wegener's Granulomatosis

Wegener's Granulomatosis

United Kingdom, Germany, Sweden, Czech Republic, Denmark, Netherlands
Thomayer University Hospital
Masaryk University

Recruiting

Czech AATD Registry

Alpha-1-antitrypsin Deficiency

Czechia
ChemoCentryx

Completed

A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis (ADVOCATE)

ANCA-Associated Vasculitis

United States, Australia, Belgium, Canada, France, Italy, Japan, Netherlands, Spain, United Kingdom, Austria, Czechia, Denmark, Germany, Hungary, Ireland, New Zealand, Norway, Sweden, Switzerland
General University Hospital, Prague

Recruiting

Ursodeoxycholic Acid in Patients With NAFLD - Clinical Observation (URSO)

Non-Alcoholic Fatty Liver Disease

Czechia
University of Ostrava
University Hospital Ostrava; University Hospital Olomouc; Palacky University

Recruiting

Bariatric Endoscopy and NAFLD

Obesity | NAFLD | Liver Steatosis | Liver Fibrosis

Czechia
General University Hospital, Prague

Recruiting

Lifestyle Modification in the Treatment of NAFLD.

NAFLD

Czechia
Military University Hospital, Prague
University of Chemistry and Technology, Prague

Unknown

Novel Molecular Spectrometric Biomarkers in Blood Plasma as an Early Diagnostic Tool in HCC

Hepatocellular Carcinoma | Cirrhosis, Liver | Liver Cancer

Czechia
Human Genome Sciences Inc., a GSK Company
GlaxoSmithKline

Completed

Belimumab in Remission of VASculitis (BREVAS)

Vasculitis

United States, Australia, France, Spain, Italy, Peru, Belgium, Canada, Germany, Romania, Mexico, United Kingdom, Hungary, Ireland, Poland, Switzerland, Czechia, Russian Federation, Norway, Sweden
University Hospital Ostrava

Active, not recruiting

Bariatric Endoscopy and NAFLD

Obesity | NAFLD | Liver Steatosis | Liver Fibrosis

Czechia
Cambridge University Hospitals NHS Foundation Trust
University of Pennsylvania; Roche Pharma AG; Genentech, Inc.; Arthritis Research...

Completed

Rituximab Vasculitis Maintenance Study (RITAZAREM)

Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Wegener Granulomatosis

United States, Canada, United Kingdom, Sweden, New Zealand, Ireland, Australia, Italy, Czechia, Japan
General University Hospital, Prague

Completed

Polyunsaturated Fatty Acids in Patients With NAFLD.

NAFLD

Czechia
Bristol-Myers Squibb

Completed

An Investigational Study to Evaluate Experimental Medication BMS-986036 in Participants With Different Levels of Kidney Function

NAFLD | Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

Hungary, Czechia
InflaRx GmbH

Completed

Study of IFX-1 to Replace Steroids in Patients With Granulomatosis With Polyangiitis and Microscopic Polyangiitis. (IXchange)

Granulomatosis With Polyangiitis (GPA) | Microscopic Polyangiitis (MPA)

Germany, Russian Federation, Belgium, France, Spain, Czechia, Italy, Netherlands, Sweden, Switzerland, United Kingdom
ChemoCentryx

Completed

A Study to Evaluate the Safety and Efficacy of CCX168 in Subjects With ANCA-Associated Vasculitis

Vasculitis

France, United Kingdom, Germany, Belgium, Poland, Netherlands, Hungary, Austria, Sweden, Czechia
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function

Hepatic Insufficiency

Hungary, Czechia, Slovakia
University Hospital Ostrava
University of Ostrava

Completed

Bariatric Surgery and Fatty Liver Disease

Hypertension | Diabetes | Morbid Obesity

Czechia
Hoffmann-La Roche

Completed

Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib

Hepatic Impairment

Czechia, Slovakia
Bristol-Myers Squibb

Completed

An Investigational Study of BMS-986165 in Participants With Normal Liver Function and Participants With Mild to Severe Liver Damage

Healthy Volunteers | Liver Dysfunction

Czechia, Hungary, Slovakia
University of Pennsylvania
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Plasma Exchange and Glucocorticoids for Treatment of Anti-Neutrophil Cytoplasm Antibody (ANCA) - Associated Vasculitis (PEXIVAS)

Microscopic Polyangiitis (MPA) | Granulomatosis With Polyangiitis (Wegener's) (GPA)

United States, Belgium, France, United Kingdom, Denmark, Canada, Japan, Australia, New Zealand, Sweden, Czechia, Italy, Greece, Mexico, Norway
Takeda

Completed

A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954

Healthy Volunteers | Hepatic Impairment

Czechia, Slovakia
Mitsubishi Tanabe Pharma Corporation

Completed

PK Study in Subjects With Severe Hepatic Impairment (MCI-186-E05 HP)

Healthy | Severe Hepatic Impairment

Czechia, Hungary, Slovakia
GlaxoSmithKline

Recruiting

Efficacy and Safety of Depemokimab Compared With Mepolizumab in Adults With Relapsing or Refractory Eosinophilic Granulomatosis With Polyangiitis (EGPA) (OCEAN)

Eosinophilic Granulomatosis With Polyangiitis

Canada, France, Italy, Spain, Belgium, Korea, Republic of, United States, Japan, China, Czechia, Hungary, Israel, Portugal, Poland, Netherlands, United Kingdom, Austria, Argentina, Australia, Brazil, Germany, Sweden
GlaxoSmithKline

Completed

A Study to Assess the Effects of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Mild, Moderate or Severe Hepatic Impairment.

Asthma

Czechia, Slovakia
GlaxoSmithKline

Completed

Evaluation of Immune Memory to Twinrix or Comparator by Challenge Dose Administration 4 Years After Primary Vaccination

Hepatitis B | Hepatitis A

Belgium, Czechia
GlaxoSmithKline

Completed

Evaluation of Antibody Persistence & Immune Memory in Subjects Vaccinated During Adolescence With Twinrix™

Hepatitis B | Hepatitis A

Belgium, Czechia
University Hospital, Aachen

Completed

HOPE for Human Extended Criteria and Donation After Brain Death Donor (ECD-DBD) Liver Allografts (HOPE-ECD-DBD)

Liver Transplant | Hepatocellular Injury

Germany, Czechia
Pfizer

Completed

A STUDY TO COMPARE THE PHARMACOKINETICS OF PF-06835919 IN PARTICIPANTS WITH AND WITHOUT HEPATIC IMPAIRMENT

Hepatic Impairment | Healthy Participants

Czechia, Slovakia, Belgium
University of Oxford
American College of Rheumatology; The European League Against Rheumatism (EULAR) and other collaborators

Unknown

American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Diagnostic and Classification Criteria for Primary Systemic Vasculitis (DCVAS)

Giant Cell Arteritis | Wegener's Granulomatosis | Microscopic Polyangiitis | Polyarteritis Nodosa | Takayasu Arteritis | Churg Strauss Syndrome

Korea, Republic of, United States, Germany, Australia, Japan, Ireland, Belgium, Italy, Denmark, Slovenia, Switzerland, Canada, Argentina, Austria, China, Czech Republic, Egypt, Finland, France, Hungary, India, Mexico, Netherlands, New... and more
Pfizer

Completed

Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States, Belgium, Czechia, Slovakia
Novartis Pharmaceuticals

Recruiting

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR) (REPLENISH)

Polymyalgia Rheumatica

United States, Australia, Germany, Belgium, France, Spain, Italy, Lebanon, Switzerland, Japan, Israel, Denmark, Argentina, Netherlands, Colombia, Chile, Hungary, Poland, Turkey, Czechia, Brazil, South Africa, Mexico, Canada, United Kingdom
Novartis Pharmaceuticals

Active, not recruiting

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Giant Cell Arteritis (GCA)

Giant Cell Arteritis (GCA)

United States, Belgium, Hungary, Italy, Turkey, Austria, Spain, Switzerland, France, Germany, Israel, Australia, Denmark, Greece, United Kingdom, Guatemala, Bulgaria, Czechia, Estonia, Argentina, Canada, Brazil, Sweden, Finland, Poland, P... and more
GlaxoSmithKline

Completed

Evaluation Of Fondaparinux (Also Called ARIXTRA) 2.5 mg Subcutaneously Once Daily For The Treatment Of Superficial Thrombophlebitis (Also Known As Superficial Vein Thrombosis)

Thrombosis, Venous

Netherlands, Spain, Germany, Italy, Poland, Russian Federation, France, Israel, Estonia, Hungary, Slovakia, Latvia, Greece, Ukraine, Czech Republic, Switzerland, Bulgaria
NovoCure GmbH

Unknown

Effect of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Sorafenib For Advanced Hepatocellular Carcinoma (HCC) (HEPANOVA)

Hepatocellular Carcinoma

Italy, Czechia, France, Germany, Poland, Spain
Astellas Pharma Europe Ltd.

Completed

A Study to Compare How the Body Absorbs and Processes Two Different Formulations of the Anti-rejection Medication Tacrolimus (Advagraf® or Prograf®) in Children Receiving an Organ Transplant, and How Safe and Effective They Are Over a Longer Period of Time

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Czechia, France, Italy, Poland, United Kingdom
AbbVie

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of Upadacitinib in Participants With Giant Cell Arteritis (SELECT-GCA)

Giant Cell Arteritis (GCA)

United States, Australia, Austria, Belgium, Canada, Czechia, Denmark, France, Germany, Greece, Hungary, Israel, Italy, Japan, Netherlands, New Zealand, Norway, Portugal, Romania, Russian Federation, Spain, Sweden, Switzerland, United...
Pierre Fabre Medicament

Withdrawn

Hepatic Impairment Study of Encorafenib in Combination With Binimetinib in BRAF Melanoma

Hepatic Impairment | Metastatic Melanoma | Unresectable Melanoma | BRAF V600 Mutation

Spain, Czechia, Italy
Universitaire Ziekenhuizen KU Leuven

Terminated

Supplemental Corticosteroids in Cirrhotic Hypotensive Patients With Suspicion of Sepsis (SCOTCH;)

Liver Cirrhosis

Spain, United Kingdom, Denmark, Germany, Czechia, Belgium, Italy
Charles University, Czech Republic
IGA MZ, Czech Republic

Unknown

Role of Heme Oxygenase in the Pathogenesis of Hepatocellular Injury in Chronic Hepatitis C Virus (HCV) Infection

Nonalcoholic Steatohepatitis | Chronic HCV Infection

Czech Republic
Vertex Pharmaceuticals Incorporated

Completed

Study of Lumacaftor in Combination With Ivacaftor in Subjects With Moderate Hepatic Impairment and Healthy Subjects

Healthy | Hepatic Impairment

Slovakia, Czech Republic
AstraZeneca
PRA Health Sciences

Completed

Pharmacokinetics, Safety & Tolerability of ZD4054 (Zibotentan) in Subjects With Normal, Mild, Moderate and Severe Hepatic Impairment

Hepatic Impairment

Czech Republic
Janssen Infectious Diseases BVBA

Completed

A Study to Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment

Hepatic Impairment

Germany, Czech Republic
Astellas Pharma Europe Ltd.

Active, not recruiting

Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Intestine Transplantation

Belgium, Czechia, France, Germany, Italy, Poland, United Kingdom
Novartis Pharmaceuticals

Completed

Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Liver Transplant Recipients With Additional 12-month Follow-up and Long-term Extension (CONTRAIL I)

Liver Transplant Rejection

United States, Belgium, Germany, Spain, Argentina, Netherlands, Italy, Hungary, France, Czechia
Hoffmann-La Roche

Completed

A Study of The Relationship Between Drop in Hemoglobin and Sustained Virological Response in Patients With Chronic Hepatitis C Treated With Copegus (Ribavirin) and Pegasys (Peginterferon Alfa-2a)

Hepatitis C, Chronic

Czech Republic
GlaxoSmithKline

Completed

Effect of Risk Factors Likely to Influence Immuno of Combined Hepatitis A & B Vacc vs Monovalent Hepatitis A & B Vacc

Hepatitis B | Hepatitis A

Germany, Belgium, Czechia
Charles University, Czech Republic
Institute for Clinical and Experimental Medicine; General University Hospital... and other collaborators

Completed

Biliverdin Reductase A in Chronic Hepatitis C Virus Infection

Hepatitis C, Chronic

Czech Republic
GlaxoSmithKline

Withdrawn

Evaluation of the Long-term Hepatitis A and B Antibody Persistence in Healthy Adult Subjects, Primed 16 to 20 Years Earlier With GSK Biologicals' Combined Hepatitis A and B Vaccine, Twinrix® (SB208127) in Study HAB-084 (208127/084)

Hepatitis B | Hepatitis A

Czech Republic
Henogen

Completed

Consistency Study of Three Lots of Henogen's Adjuvanted Hepatitis B Vaccine When Given in 0, 1 Month Schedule

Hepatitis B

Czech Republic

Clinical Trials on Livedo Vasculitis in Czechia

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