Clinical Trials on Liver Failure, Acute

Total 37910 results

Yonsei University

Completed

A Comparison of Propofol Based Total Intravenous Anesthesia and Desflurane Based Balanced Anesthesia on Hepatic Protection During Living-donor Liver Transplantation

End Stage Liver Disease

Korea, Republic of
University Hospital, Lille
Ministry of Health, France

Recruiting

Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies (SCINTIVOL)

Hepatic Insufficiency

France
National Natural Science Foundation of China

Active, not recruiting

A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF) (RNLV)

Liver Failure

China
Akdeniz University

Completed

Evaluation of HDL Subfraction Changes and HDL-Associated Enzymes in Liver Failure Patients and Healthy Donors

Liver Failure

Turkey
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function

Hepatic Insufficiency

Hungary, Czechia, Slovakia
Denovo Biopharma LLC

Completed

A Study of LY2140023 in Hepatically-Impaired Participants

Hepatic Insufficiency

Germany, Hungary
Celgene

Completed

Pharmacogenetics Sampling of the CC-90007-CP-003 Study Cohort

Hepatic Insufficiency

United States
The University of Hong Kong

Unknown

A Prospective Randomized Controlled Trial on the Use of Cerebral Oximetry in Adult Chinese Patients Undergoing Liver Transplantation (LT)

Liver Failure

Hong Kong, China
Eli Lilly and Company

Completed

A Study of Abemaciclib in Participants With Varying Degrees of Liver Impairment

Hepatic Insufficiency

United States
Humedics GmbH

Completed

Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test

Liver Failure

Germany
University of Edinburgh
NHS Lothian

Unknown

The Relationship of Initial Liver Profile and Outcome After Transplantation

Liver Failure

United Kingdom
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Single-Dose Pharmacokinetics and Safety of Oral Lofexidine in Hepatically-Impaired Subjects

Liver Failure

United States
Stanley Dudrick's Memorial Hospital

Completed

Parenteral Lipid Emulsions and the Liver Function

Liver Failure

Poland
Veloxis Pharmaceuticals
CTI Clinical Trial and Consulting Services

Completed

Pharmacokinetics of LCP-Tacro in Stable Liver Transplant Patients

Liver Failure

United States
University Health Network, Toronto
University of Waterloo

Completed

SPME For Metabolomics And Concomitant Measurements Of Rocuronium Bromide Levels In Liver Transplantation

Liver Failure

Canada
Fundacion para la Formacion e Investigacion Sanitarias...

Completed

Extracorporeal Photopheresis After Liver Transplant

Hepatic Insufficiency

Spain
Boehringer Ingelheim

Completed

Pharmacokinetics, Safety and Tolerability of BIIL 284 BS in Patients With Hepatic Impairment in Comparison to Healthy Volunteers

Hepatic Insufficiency
Boehringer Ingelheim

Completed

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate in Patients With Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic Function

Hepatic Insufficiency
Pfizer

Completed

Evaluation Of Hepatic Impairment On AG-013736 Pharmacokinetics

Hepatic Insufficiency

United States
Vertex Pharmaceuticals Incorporated

Completed

Study of Telaprevir in Subjects With Hepatic Impairment

Hepatic Insufficiency

United States
RenaMed Biologics

Terminated

Study to Evaluate the Safety and Efficacy of the Renal Assist Device in Patients With Acute Renal Failure

Kidney Failure, Acute

United States
Cassava Sciences, Inc.

Not yet recruiting

A Pharmacokinetic Study of Simufilam in Subjects With Impaired Hepatic Function

Hepatic Insufficiency
Chiesi Hungary Ltd.
Chiesi Slovenija, d.o.o.

Recruiting

Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant Patients (LTA)

Liver Failure

Hungary, Slovenia
The University of Hong Kong

Recruiting

Randomized Trial of Hepaticojejunostomy Versus Duct-to-duct Anastomosis in Right Lobe Living Donor Liver Transplantation

Liver Failure

Hong Kong
The Cleveland Clinic

Active, not recruiting

SVC and Its Relationship to CVP Measurements in Liver Transplantation

Liver Failure

United States
Boehringer Ingelheim

Completed

A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Liver Problems

Hepatic Insufficiency

Germany
Shanghai Zhongshan Hospital

Completed

Gd-EOB-DTPA-enhanced T1 Map for Predicting Postoperative Liver Failure

Liver Failure

China
The Cleveland Clinic

Completed

A Randomized Controlled Clinical Trial of Thymoglobulin® After Liver Transplantation

Liver Failure

United States
Axcella Health, Inc

Completed

Study of the Safety and Tolerability of AXA1665 in Subjects With Mild and Moderate Hepatic Insufficiency

Hepatic Insufficiency

United States
University of Manitoba

Completed

Comparative FK506 Drug Levels of Once Daily Advagraf in First Nations and Caucasian Patients With Liver Transplants

Liver Failure

Canada
Genentech, Inc.

Completed

A Study of Ipatasertib in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Participants

Hepatic Insufficiency

United States
Eli Lilly and Company

Completed

A Study of Evacetrapib (LY2484595) in Participants With Hepatic (Liver) Impairment

Hepatic Insufficiency

United States
Merck Sharp & Dohme LLC

Completed

Assessment of Pharmacokinetics of Single Dose Odanacatib (MK-0822) in Participants With Moderate Hepatic Insufficiency (MK-0822-070)

Hepatic Insufficiency
McGill University Health Centre/Research Institute...

Unknown

Preoperative Glucose Infusion: a Novel Strategy to Improve Liver Function After Liver Resection

Liver Failure | Hepatic Insufficiency

Canada
Korea University Anam Hospital
Pharmbio Korea Co., Ltd.

Unknown

The Effect of Somatostatin for Treatment of Post Hepatectomy Liver Failure (PHLF)

Liver Failure

Korea, Republic of
Debiopharm International SA

Completed

Evaluate the Pharmacokinetics, Safety, and Tolerability of Alisporivir in Subjects With Hepatic Impairment Compared to Healthy Subjects

Hepatic Insufficiency

United States
Virginia Commonwealth University

Withdrawn

Hepatocyte Transplantation in Liver Failure

Liver Failure

United States
Boehringer Ingelheim

Completed

Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy Subjects

Hepatic Insufficiency
Vital Therapies, Inc.

No longer available

Use of the ELAD® in Patients With Liver Failure to Provide Expanded Access With Cost Recovery

Liver Failure
Third Affiliated Hospital, Sun Yat-Sen University

Unknown

Safety and Efficacy of Diverse Mesenchymal Stem Cells Transplantation for Liver Failure

Liver Failure

China
University Hospital, Gentofte, Copenhagen

Completed

Single Dose of 9-cis-retinoic Acid in Hepatic Patients

Hepatic Insufficiency

Denmark
Bristol-Myers Squibb

Completed

Hepatic Impaired Subjects Compared to Healthy Subjects Receiving Multi-dose BMS-650032

Hepatic Insufficiency

United States
Pfizer

Completed

A Safety and Tolerability Study of CP-690,550 in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Insufficiency

United States
Baylor College of Medicine

Terminated

Trial of Calcineurin Inhibitor-Sparing Immunosuppression Regimen in Pediatric Liver Transplantation

Renal Insufficiency | Renal Failure | End-stage Liver Disease

United States
Dr. F. Köhler Chemie GmbH

Recruiting

Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas)

Kidney Failure | Liver Failure, Chronic | Kidney-Pancreas Failure

Austria
University of California, Los Angeles

Enrolling by invitation

Angiotensin 2 for AKI After OLT

Acute Kidney Injury | Liver Transplant; Complications | Cirrhosis, Liver | End Stage Liver DIsease

United States
Chandan K Sen
Carotech Inc.

Completed

Human Tissue Distribution of Orally Supplemented Natural Vitamin E Tocotrienol

End Stage Liver Disease | Healthy Subjects | Morbid Obesity | Pulmonary Failure | End Stage Cardiac Failure | Recalcitrant Epilepsy Requiring Surgery

United States
Tarek M. El-Achkar
Satellite Healthcare; Triax Pharmaceuticals

Completed

Minocycline to Prevent Acute Kidney Injury After Cardiac Surgery

Kidney Failure, Acute | Acute Kidney Insufficiency

United States
University of Zurich
University Ghent; University Hospital of Sao Paulo, Brazil

Completed

Conditioning With Volatile Anesthetics in Liver Transplantation

End-stage Liver Disease

Switzerland
Wenzhou Medical University

Completed

Study of the Model to Predict 3-month Mortality Risk of Acute-on-chronic Hepatitis B Liver Failure

Acute-on-chronic Hepatitis B Liver Failure

China

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