Clinical Trials on Local Anesthetic Systemic Toxicity in Italy

Total 59 results

Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Ropivacaine Plasma Concentration With or Without Epinephrine for Posterior Quadratus Lumborum Block

Anesthesia, Local | Local Anesthetic Systemic Toxicity

Italy
University of Turin, Italy

Recruiting

Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery

Postoperative Pain | Regional Anesthesia Morbidity | Local Anesthetic Toxicity

Italy
University of Campania "Luigi Vanvitelli"

Completed

Efficacy of Differents Anaesthetics in Mandibular Third Molar Germectomy

Local Anesthetic Efficacy

Italy
San Salvatore Hospital of L'Aquila

Completed

Anesthetic Efficacy of PECS II Block and Parasternal Block

Anesthesia, Local

Italy
San Salvatore Hospital of L'Aquila

Recruiting

Thoracic Intervertebral Foramen Block

Anesthesia, Local | Anesthesia; Functional | Spinal Cord

Italy
Istituto Ortopedico Rizzoli

Completed

Impatto Emodinamico Dell'Anestesia Subaracnoidea Titrata Versus Tecnica Single-shot Nei Pazienti Sottoposti ad Artroprotesi d'Anca. RCT (NINO)

Anesthesia, Local | Anesthesia; Adverse Effect

Italy
European e-Learning School in Obstetric Anesthesia

Completed

Epidural Catheter Location by Epidural Pressure Waveform

Anesthesia, Local

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Erector Spinae Plane Block (ESPB) Versus Quadratus Lumborum Block (QLB) for Postoperative Analgesia After Caesarean Section

Anesthesia, Local | Cesarean Section Complications | Pain, Post Operative | Obstetric Anesthesia Problems

Italy
University of Padova

Withdrawn

Comparison of Erector Spinae Plane Block With PECS II Block in Patients Undergoing Breast Cancer Surgery

Breast Cancer | Anesthesia, Local

Italy
University of Padova

Recruiting

ESP Block Versus Wound Infiltration for Laminectomy

Pain, Postoperative | Anesthesia, Local | Surgery | Opioid Use

Italy
Vittore Buzzi Children's Hospital

Recruiting

Lung Ultrasound Guided Choice of Best Positive End-Expiratory Pressure in Neonatal Anesthesia

Oxygen Toxicity | Anesthesia; Adverse Effect

Italy
Campus Bio-Medico University

Unknown

Volume De-escalation in Neoadjuvant Radiochemotherapy of Rectal Cancer

Toxicity

Italy
Azienda Ospedaliera Città della Salute e della...

Completed

Subclinical Cardio-toxicities Evaluation With Strain Rate Echocardiography After Chemotherapy and/or Mediastinal Radiotherapy in Patient With Lymphoma (Cardiocare)

Lymphoma, Non-Hodgkin | Hodgkin Lymphoma | Toxicity, Cardiac

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Voice Telerehabilitation

Vocal Fold Palsy

Italy
Ospedale San Carlo Borromeo

Active, not recruiting

Panitumumab Skin Toxicity Prevention Trial (PaSTo)

Colorectal Cancer Metastatic | Skin Toxicity

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Non-phonatory Exercises in Patients With Unilateral Vocal Fold Paralysis Post-thyroidectomy (ENFP)

Unilateral Vocal Cord Paralysis

Italy
Azienda Ospedaliera di Padova

Completed

Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study) (KISS)

Analgesia | Sedation Complication | Bronchospasm | Ketamine Toxicity

Italy
Humanitas Clinical and Research Center

Completed

Fluid Challenge Infusion and Response (REFILL)

Anesthesia, General | Cardiovascular System | Neurosurgery

Italy
Federico Longhini

Completed

Anaesthesia With or Without Rocuronium in Intubation and Intraoperative Nerve-monitoring During Thyroid Surgery.

Thyroid | Anesthesia Intubation Complication | Neuromuscular Blockade | Anesthesia Complication

Italy
University of Padova

Recruiting

Sonographic Predictors of Difficult Epidural Placement. (PREC-EPI)

Anesthesia | Safety Issues | Epidural; Anesthesia, Headache

Italy
Oncologia Medica dell'Ospedale Fatebenefratelli
Mario Negri Institute for Pharmacological Research

Completed

PAINTER: Polymorphism And INcidence of Toxicity in ERibulin Treatment

Metastatic Breast Cancer | Toxicity | Neurotoxicity | Adverse Drug Event | Drug Toxicity

Italy
IRCCS San Raffaele

Not yet recruiting

Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy

Epilepsy | Focal Epilepsy

Italy
University of Roma La Sapienza
Ipsen

Unknown

Motor and Non-motor Symptoms in Cervical Dystonia (Royal)

Dystonia, Focal

Italy
Neurocrine Biosciences

Terminated

Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Australia, Belgium, Czechia, France, Hungary, Italy
Neurocrine Biosciences

Completed

A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Belgium, Czechia, France, Italy, Australia, Hungary, United Kingdom
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Effect of Epidural Analgesia on Labour, Neonatal and Maternal Outcomes.

Labor Pain | Regional Anesthesia Morbidity | Delivery Complication

Italy
Aziende Chimiche Riunite Angelini Francesco S.p.A
Iqvia Pty Ltd

Recruiting

Cenobamate in Adults With Focal-Onset Seizures (BLESS)

Epilepsy | Neurological Disorder | Focal-Onset Seizure

Italy
Ospedale Edoardo Bassini

Recruiting

Comparison of PENG Associated With LFCN Block Versus FICB for Multimodal Analgesic Management in THA

Post Operative Pain | Regional Anesthesia Morbidity | Arthropathy of Hip | Hip Arthropathy | Anesthesia Complication

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Observational Retrospective Study on Spinal Analgesia in Laparoscopic and Laparotomic Hysterectomy (SPIN_GYN)

Pain, Postoperative | Hysterectomy | Anesthesia, Spinal | Morphine

Italy
Fondazione Policlinico Universitario Campus Bio-Medico

Completed

REduced Pain After Bariatric Surgery - Sleeve Gastrectomy (REPABS-SG)

Pain | Postoperative Pain | Analgesia | Acute Pain | Bariatric Surgery Candidate | Anesthesia

Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Completed

Regional Anesthesia Versus General Anesthesia

Postoperative Pain | Anesthesia

Italy
University of Parma

Terminated

Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery

Pain, Postoperative | Anesthesia Recovery Period

Italy
Azienda Ospedaliero, Universitaria Pisana

Completed

Volume Effect in Peng Block for Total Hip Replacement (volupeng)

Anesthesia | Post Operative Pain

Italy
Ospedale di Circolo - Fondazione Macchi

Completed

Approach to Continuous Sciatic Nerve Block for Orthopedic Procedures in Day Surgery With Two Different Techniques

Postoperative Pain | Regional Anesthesia Morbidity

Italy
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

Focal Onset Seizures

United States, Spain, Italy, Croatia, Portugal, Poland, Chile, Argentina, Austria, Czechia
Jazz Pharmaceuticals

Completed

A Study of GWP42006 in People With Focal Seizures - Part B

Epilepsy | Focal Seizures

Italy, Poland, United Kingdom, Spain, Hungary, Czechia
University of Padova

Recruiting

Predictive Factors for the Effectiveness of the Ilioinguinal Iliohypogastric Nerve Block for Hernia Surgery (VALI)

Hernia Inguinal | Regional Anesthesia | Pain Postoperative

Italy
University of Padova

Recruiting

Manually Controlled Infusion vs Target Controlled Infusion for StrokeThrombectomy (HASTE)

Anesthesia | Stroke, Ischemic | Hemodynamic Instability | Stroke/Brain Attack

Italy
University of Roma La Sapienza

Unknown

Postanesthesia Cognitive Recovery and Neuropsychologic Complications

Anesthesia Recovery Period | Mental Competency | Delirium, Dementia, Cognitive Disorders | Neurobehavioural Manifestation

Italy
Xenon Pharmaceuticals Inc.
Novotech Health Holdings Pte. Ltd.

Active, not recruiting

A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy (X-TOLE)

Focal Epilepsy

Spain, United States, Ukraine, Canada, United Kingdom, Germany, Georgia, Italy, Moldova, Republic of
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE2)

Focal Onset Seizures

United States, Spain, Australia, Poland, Canada, Bulgaria, Italy, United Kingdom
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Erector Spinae Plane Block in Uniportal VATS (ESPB-UVATS)

Acute Pain | Thoracic Surgery | Post-Operative Pain, Chronic | Locoregional Anesthesia | Post-operative Complications | Uniportal Video Assisted Thoracic Surgery (U-VATS) | Lung Resections

Italy
Università degli Studi dell'Aquila

Completed

Dexamethasone for the Prevention of Recurrent Laryngeal Nerve Palsy

Benign Neoplasm of Thyroid Gland | Malignant Neoplasm of Thyroid

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Ultrasound-assisted or Landmark-based Intrathecal Administration of Nusinersen in Adult Patients With Spinal Muscular Atrophy (The EchoSpin Study) (EchoSpin)

Ultrasonography | Spinal Muscular Atrophy | Anesthesia, Spinal | Spinal Puncture Complications

Italy
G1 Therapeutics, Inc.

Terminated

Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving FOLFOXIRI/Bevacizumab for Metastatic Colorectal Cancer (mCRC): (PRESERVE1)

Colorectal Cancer Metastatic | Chemotherapeutic Toxicity | Myelosuppression-Adult

China, Spain, United States, Hungary, United Kingdom, Poland, Ukraine, Italy
UCB Biopharma S.P.R.L.

Completed

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy (ARISE)

Focal-Onset Seizures | Drug-resistant Epilepsy

United States, Australia, Belgium, Bulgaria, Canada, Czechia, France, Germany, Hungary, Italy, Japan, Lithuania, Mexico, Poland, Portugal, Slovakia, Spain, Turkey, United Kingdom
Light Sciences Oncology

Completed

Phase 3 Trial of Litx™ Plus Chemotherapy vs. Chemotherapy Only Treating Colorectal Cancer Patients With Recurrent Liver Metastases

Neoplasm Metastasis | Colorectal Neoplasms | Liver Metastases | Neoplasm Recurrence, Local

Sweden, India, Austria, Serbia, Germany, Romania, Croatia, Bosnia and Herzegovina, Italy, Latvia, Poland, Russian Federation, Ukraine
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Spain, Sweden, Switzerlan... and more
UCB Biopharma SRL

Terminated

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Lithuania, Mexico, Poland, Romania, Serbia, Slovakia, Spain, Turk... and more
Murdoch Childrens Research Institute
Baylor College of Medicine; Children's Hospital of Philadelphia; Boston Children... and other collaborators

Active, not recruiting

A Study to Compare the Long-term Outcomes After Two Different Anaesthetics (TREX)

Child Development | Anesthesia | Neurotoxicity

United States, Australia, Italy, Spain

Clinical Trials on Local Anesthetic Systemic Toxicity in Italy

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Poland

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations