Clinical Trials on Local Disease

Total 382453 results

Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Image-Guided Biopsies in Identifying Mechanisms of Resistance in Participants With Metastatic Castration Resistant Prostate Cancer Undergoing Radioligand Therapy

Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer
Medical University of Lublin

Completed

Identification of the UDI-6 and the IIQ-7 Cutoff Scores in Urinary Incontinent Women

Quality of Life | Urinary Incontinence | Urinary Incontinence,Stress

Poland
Royal Surrey County Hospital NHS Foundation Trust
Kyowa Hakko Kirin UK, Ltd.

Completed

Study of Opioid-Induced Constipation 2 Project (StOIC-2)

Cancer | Opioid-induced Constipation | Cancer Pain

United Kingdom
Roswell Park Cancer Institute
Iovance Biotherapeutics, Inc.

Withdrawn

Adoptive Cell Therapy With (LN-145) in Combination With Pembrolizumab in Treating Patients With Unresectable or Metastatic Transitional Cell Cancer Who Have Failed Cisplatin-Based Chemotherapy

Metastatic Bladder Urothelial Carcinoma | Metastatic Renal Pelvis Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Metastatic Urethral Urothelial Carcinoma | Unresectable Renal Pelvis Urothelial Carcinoma | Unresectable Ureter Urothelial Carcinoma

United States
University of California, Los Angeles
Los Angeles County Department of Public Health

Completed

Increasing Human Papillomavirus Vaccine Uptake in Low-Income, Ethnic Minority Adolescents in Los Angeles County

Human Papilloma Virus Infection

United States
Mental Health Services in the Capital Region, Denmark
Danish Center for Sleep Medicine

Completed

Treatment of Sleep Disturbances in Trauma-affected Refugees (PTF5)

Depression | Post Traumatic Stress Disorder

Denmark
Boston Medical Center
The New School for Social Research; Children's Bureau - Administration for...

Withdrawn

Project BELONG: Breaking the Cycle of Intergenerational Family Violence and Trauma

Parental Stress | Parenting | Family Relations | Family Conflict | Mother-child Relations | Parent Child Abuse | Childhood Disorder of Social Functioning, Unspecified

United States
Yale University
Patient-Centered Outcomes Research Institute

Completed

Comparative Effectiveness of Sentinel Lymph Node Biopsy for Ductal Carcinoma In Situ

Ductal Carcinoma In Situ

United States
University of Padova
Maran Eleonora

Unknown

Post Operative Cognitive Dysfunction and Delirium After Spinal Surgery

Emergence Delirium | Post-Operative Cognitive Dysfunction
Instituto de Investigacion Sanitaria La Fe

Unknown

Mid Term Safety and Efficacy of ALTIS® Single Incision Sling for Female Stress Urinary Incontinence (SUI).

Urinary Incontinence,Stress

Spain
Ezra Cohen
SignalRX Pharmaceuticals, Inc.

Terminated

SF1126 in Recurrent or Progressive SCCHN and Mutations in PIK3CA Gene and/or PI-3 Kinase Pathway Genes

Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma

United States
Medical University of South Carolina
Shire

Completed

Evaluating the Methylphenidate Patch to Treat Former Stimulant Users With ADHD

Adult Attention Deficit Hyperactivity Disorder (ADHD)

United States
Mayo Clinic
National Cancer Institute (NCI)

Withdrawn

Gemcitabine Hydrochloride, Cisplatin, and AGS-003-BLD in Treating Patients With Muscle-Invasive Bladder Cancer Undergoing Surgery

Infiltrating Bladder Urothelial Carcinoma | Stage II Bladder Urothelial Carcinoma | Stage IV Bladder Urothelial Carcinoma | Stage III Bladder Urothelial Carcinoma

United States
Alcobra Ltd.

Completed

A 6 Week Study of MG01CI 1400 mg Compared With Placebo in Adults With ADHD ( Attention Deficit/Hyperactivity )

ADHD | Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

United States, Israel
National Institute on Drug Abuse (NIDA)
Sunovion

Completed

A Timeline Study of Alcohol Use and Its Relationship to Insomnia

Insomnia | Alcohol Problem

United States
Medway NHS Foundation Trust

Completed

Vibration Training and Pelvic Floor Muscle Strength in Females With Stress Urinary Incontinence

Urinary Stress Incontinence

United Kingdom
ASTORA Women's Health

Terminated

Collection of Long Term Patient Outcomes Data Following Implantation of AMS Surgical Devices (CAPTURE)

Pelvic Organ Prolapse | Female Stress Incontinence

United States, Spain, Slovenia, France, United Kingdom, Canada, Germany, South Africa
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Trial of Ipilimumab After Isolated Limb Perfusion, in Patients With Metastases Melanoma (ILP+/-IPI)

In-transit Metastases Melanoma Stage IIIB and IIIC

France
Universidade Federal de Sao Carlos

Unknown

Individual Pelvic Floor Muscle Training Versus Individual With Group Versus Group for Stress Urinary Incontinence

Urinary Incontinence Stress
Sunnybrook Health Sciences Centre

Terminated

Diagnostic Study of Early Breast Cancer Using Ultrasound

Ductal Carcinoma In-situ

Canada
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

Melphalan and Whole-Body Hyperthermia in Treating Patients With Advanced Melanoma

Melanoma (Skin)

United States
City of Hope Medical Center

Terminated

Nelfinavir Mesylate in Treating Patients With Recurrent, Metastatic, or Unresectable Liposarcoma

Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Adult Liposarcoma

United States
State University of New York - Upstate Medical...
University at Buffalo

Completed

Neuropsychoanalytic Treatment of Failed Back Surgery Syndrome-Opioid Dependence

Pain
Swansea University
Cardiff University

Completed

Wales Electronic Cohort for Children (WECC)

Premature Birth | Low Birth Weight | Childhood Obesity | Macrosomia | Poverty

United Kingdom
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Metastatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Melanoma (Skin)

United States
National Cancer Institute (NCI)

Completed

BMS-275291 in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy

Recurrent Prostate Cancer | Bone Metastases | Hormone-resistant Prostate Cancer | Adenocarcinoma of the Prostate | Stage IV Prostate Cancer

United States
Windy Hill Medical, Inc.

Unknown

Study Of Intraductal Carboplatin In Women With Ductal Carcinoma In Situ (DCIS)

Ductal Carcinoma In Situ

United States
Memorial Sloan Kettering Cancer Center

Completed

Trial of Prophylactic Versus Empirical Vancomycin for the Prevention of Streptococcal Sepsis After Hematopoietic Cell Transplantation

Hematologic Malignancies | Streptococcal Sepsis

United States
South Glasgow University Hospitals NHS Trust
Henry Smith Grant

Unknown

Transvaginal Tension Free Vaginal Tape-Obturator (TVT-O) Versus Transobturator Tape-Mentor (TOT) in the Management of Urodynamic Stress Urinary Incontinence

Urinary Stress Incontinence

United Kingdom
National Health Research Institutes, Taiwan
National Taiwan University Hospital; Mackay Memorial Hospital; China Medical... and other collaborators

Completed

Chemoprevention Study of Oral Cavity Squamous Cell Carcinoma

Squamous Cell Carcinoma | Oral Cavity

Taiwan
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditions

United States
University of Alabama at Birmingham

Recruiting

A QoL Intervention for Young African American Breast Cancer Survivors

Breast Cancer | Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer... and other conditions

United States
M.D. Anderson Cancer Center

Recruiting

Identifying Decision Making Needs for Older Adult Women With Stage I-III Breast Cancer Considering Neoadjuvant or Adjuvant Chemotherapy

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Recruiting

Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Morbidity in Patients With Stage 0-IIIA Breast Cancer Receiving Radiation Therapy, COPE Study

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
University of Washington
United States Department of Defense

Recruiting

Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
M.D. Anderson Cancer Center

Completed

Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
M.D. Anderson Cancer Center

Active, not recruiting

Precision Performance Status Assessment in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Parsaclisib With or Without Polatuzumab Vedotin Plus the Standard Drug Therapy in Patients With Newly Diagnosed, High Risk Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | Indolent Non-Hodgkin Lymphoma | Ann Arbor Stage II Diffuse Large B-Cell Lymphoma | Ann Arbor Stage III Diffuse Large B-Cell Lymphoma | Ann Arbor Stage IV Diffuse Large B-Cell Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | High Grade... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Tibetan Yoga in Improving Fatigue and Sleep in Participants With Stage I-III Breast Cancer

Breast Cancer | Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer... and other conditions

United States
University of California, San Francisco

Terminated

Impact of Breast Cancer Treatment on Joint Health, Cartilage Composition, and Bone Structure in the Knee and Hand

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Stress Test in Detecting Heart Damage in Premenopausal Women With Stage I-III Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
National Cancer Institute (NCI)

Completed

Cytarabine With or Without SCH 900776 in Treating Adult Patients With Relapsed Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Monoblastic Leukemia | Adult Acute Monocytic Leukemia | Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 | Adult Acute Myeloid Leukemia With Maturation | Adult Acute Myeloid Leukemia With Minimal Differentiation | Adult Acute... and other conditions

United States
Wake Forest University Health Sciences

Terminated

Esophagoscopy in Evaluating Treatment in Patients With Stage I-IV Head and Neck Cancer Who Are Undergoing Radiation Therapy and/or Chemotherapy

Stage I Adenoid Cystic Carcinoma of the Oral Cavity | Stage I Mucoepidermoid Carcinoma of the Oral Cavity | Stage I Squamous Cell Carcinoma of the Hypopharynx | Stage I Squamous Cell Carcinoma of the Larynx | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage I Verrucous Carcinoma... and other conditions

United States
Cardarelli Hospital

Not yet recruiting

NBI for Early Diagnosis of OPMD/OSCC (NBI_Oral)

Oral Squamous Cell Carcinoma | Oral Potentially Malignant Disorder

Italy
University Hospital of Split

Recruiting

Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle Relaxants

Anesthesia | Neuromuscular Blockade | Intraoperative Bleeding | Anesthesia Complication | Post Operative Hemorrhage | Intraoperative Blood Loss

Croatia
National Cheng-Kung University Hospital

Not yet recruiting

Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate

Schizophrenia | Schizo Affective Disorder | Symptom, Cognitive
University of British Columbia

Recruiting

Multicenter Clinical Trial of ST-02 for Ablation of Upper Tract Urothelial Carcinoma

Transitional Cell Cancer of the Renal Pelvis and Ureter | Urothelial Carcinoma of the Renal Pelvis and Ureter

Canada
University of California, San Diego
Varian Medical Systems; Epimed International

Recruiting

Cryoanalgesia to Treat Phantom Limb Pain Following Above-Knee Amputation

Amputation, Traumatic | Phantom Limb Pain | Phantom Pain Following Amputation of Lower Limb | Amputation, Surgical

United States
Medical University of Vienna

Not yet recruiting

Symptoms and Quality of Life of Patients With Suspected Endometriosis

Pain | Endometriosis | Surgery | Dysmenorrhea | Dyspareunia
University of Alabama at Birmingham

Recruiting

SIRI Checklist: An Integrated Hospital Model to Optimize HIV Prevention in Persons Who Inject Drugs (SHAPE)

HIV Infections | Opioid-Related Disorders | Pre-Exposure Prophylaxis (PrEP)

United States

Clinical Trials on Local Disease

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Medical Conditions

Drug Interventions

CROs by country

CROs in Israel

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Rare Diseases

Drug Interventions

Dietary Supplements

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