Clinical Trials on Locally Advanced Gastric Cancer

Total 5416 results

Icahn School of Medicine at Mount Sinai
National Institute of Nursing Research (NINR)

Recruiting

Tier - Palliative Care For Patients With Advanced Heart Failure or Cancer (TIER-PC)

Advanced Heart Failure | Advanced Lung Cancer | Advanced Non-colorectal Gastro-intestinal Cancer

United States
University of Utah
National Cancer Institute (NCI)

Recruiting

Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer (SHAPER) (SHAPER)

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Borderline Resectable Pancreatic Adenocarcinoma | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | Locally Advanced Unresectable Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Ductal...

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)

Unresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction

United States, Spain, Italy, Australia, Russian Federation, Taiwan, Korea, Republic of, Thailand, Canada, Turkey, Germany, Romania, United Kingdom, Hungary, Brazil, France, Japan
Hummingbird Bioscience

Recruiting

Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation

Pancreatic Cancer | Non-Small Cell Lung Cancer | Metastatic Solid Tumor | Locally Advanced Solid Tumor

Australia
University of Oxford
Cancer Research UK; Akamis Bio

Completed

Chemoradiation With Enadenotucirev as a Radiosensitiser in Locally Advanced Rectal Cancer (CEDAR)

Locally Advanced Rectal Cancer

United Kingdom
Fundación de investigación HM
Syntax for Science, S.L

Completed

A Study to Evaluate a Chemotherapy Treatment Followed by Chemo and Radiotherapy in Patients With Rectal Cancer

Locally Advanced Rectal Cancer (LARC)

Spain
Turku University Hospital
University of Turku

Active, not recruiting

MRI Guided Transurethral HIFU for Various Prostate Diseases (HIFU-PRO)

Benign Prostatic Hyperplasia | Locally Advanced Prostate Cancer | Locally Recurrent Prostate Cancer | Localised Prostate Cancer

Finland
Association of Research on the Biology of Liver...

Completed

Cetuximab + Gemox in Biliary Tract Cancer

Metastatic | Locally Advanced | Unresectable

Austria
AstraZeneca

Completed

Study of AZD9291 Plus MEDI4736 Versus AZD9291 Monotherapy in NSCLC After Previous EGFR TKI Therapy in T790M Mutation Positive Tumours (CAURAL)

Locally Advanced or Metastatic EGFR T790M+ NSCLC

Canada, Korea, Republic of, Taiwan
Hospices Civils de Lyon

Recruiting

Personalized Targeted IMMUNOtherapy-based Regimens in Recurrent GASTric Adenocarcinoma (IMMUNOGAST) (IMMUNOGAST)

Gastric Adenocarcinoma | Metastatic Gastric Cancer | Advanced Gastric Carcinoma | Metastatic Adenocarcinoma

France
Jinhua Central Hospital

Not yet recruiting

Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer (CASINOs)

Locally Advanced Rectal Cancer

China
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Preoperative Radiotherapy And ASTX660 in Rectum Cancer (PRAAR1)

Locally-advanced Rectal Cancer

France
Beijing Friendship Hospital

Recruiting

Total Neoadjuvant Therapy Combined With Tislelizumab for Local Advanced of Middle and Low Rectal Cancer

Locally Advanced Rectal Cancer

China
Shanghai Changzheng Hospital

Not yet recruiting

Preoperative Pembrolizumab Plus Bevacizumab Combined With Chemotherapy in Patients With pMMR/MSS Locally Advanced Colorectal Cancer (COBP)

Locally Advanced Colorectal Cancer
University of Miami

Recruiting

SMART TNT for the Conservative Management of Locally Advanced Rectal Cancer (SMART TNT)

Locally Advanced Rectal Cancer

United States
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

SHR-1701 in Combination With Chemotherapy and Radiotherapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Sun Yat-sen University

Not yet recruiting

Fruquintinib Plus PD-1 Antibody in pMMR / MSS Locally Advanced Rectal Cancer (LARC) With High Immune Score

Locally Advanced Rectal Cancer

China
Zhejiang Cancer Hospital

Not yet recruiting

Neoadjuvant Short-course Radiotherapy Followed by the Combination of Immunotherapy and Chemotherapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
First Affiliated Hospital of Zhejiang University
Zhejiang Cancer Hospital; First Affiliated Hospital of Wenzhou Medical University

Recruiting

A Trial of Neoadjuvant mFOLFOXIRI Versus CRT in the EMVI Positive LARC

Locally Advanced Rectal Cancer

China
Dimitri Christoforidis
Clinical Trial Unit Ente Ospedaliero Cantonale

Terminated

Observational Study on Rectal Cancer to Verify if Response After Chemo-radiotherapy Can be Predicted With a Particular Blood Test. (LiBReCa)

Locally Advanced Rectal Cancer

Switzerland
Yonsei University

Active, not recruiting

Rectal Cancer, Adjuvant Chemotherapy, FOLFOX(5-fluorouracil/Leucovorin/Oxaliplatin), Total Mesorectal Excision

Locally Advanced Rectal Cancer

Korea, Republic of
AIPING ZHOU

Completed

Neoadjuvant Triplet Chemotherapy Regimen in Patients With Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Fudan University

Unknown

The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSS Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
The First Affiliated Hospital of Xiamen University

Unknown

Triplezumab Combined With CAPEOX Regimen in Neoadjuvant Therapy for Locally Advanced Colon Cancer

Locally Advanced Colon Cancer

China
Samsung Medical Center

Terminated

Efficacy of NeoThermo-Radio-chemotherapy for LA Rectal Cancer Before Laparoscopic TME: Prospective Phase II Trial (NEOTREAT)

Locally Advanced Rectal Cancer

Korea, Republic of
Grupo de Investigación Clínica en Oncología Radioterapia

Unknown

Dose-escalation Trial of Preoperative Radiotherapy and Concurrent Chemotherapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

Spain
Fudan University

Unknown

UGT1A1 Combined With Pharmacokinetics of SN-38 in CPT-11-based CRT in Patients With Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
AbbVie (prior sponsor, Abbott)

Completed

A Clinical Study Conducted in Multiple Centers Evaluating Escalating Doses of Veliparib in Combination With Capecitabine and Radiation in Patients With Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

United States, Australia
Fudan University
The First Affiliated Hospital with Nanjing Medical University; Hubei Cancer... and other collaborators

Unknown

Trial of Capecitabine With or Without Irinotecan Driven by UGT1A1 (CinClare)

Locally Advanced Rectal Cancer

China
National Health Research Institutes, Taiwan
Mackay Memorial Hospital; Chang Gung Memorial Hospital; Taipei Veterans General... and other collaborators

Completed

Trial of Celecoxib With Preoperative Chemo- Radiation for Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

Taiwan
AstraZeneca

Completed

Combination Casodex® and Iressa™ in Locally Advanced Prostate Cancer

Locally Advanced Prostate Cancer

Norway
Wuhan Union Hospital, China
Renmin Hospital of Wuhan University

Recruiting

Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study

Locally Advanced Rectal Cancer

China
Beijing Friendship Hospital
Peking Union Medical College Hospital

Not yet recruiting

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Locally Advanced Rectal Cancer

China
JIN JING

Not yet recruiting

Assess the Efficacy of Radiotherapy and Sequential Chemotherapy and AK104 Before TME Surgery for Local CRC（AK104-IIT-13） (AK104-IIT-13)

Locally Advanced Rectal Cancer
National Cancer Center Hospital East
Japan Agency for Medical Research and Development

Recruiting

Total Neoadjuvant Therapy of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer (ENSEMBLE) (ENSEMBLE)

Locally Advanced Rectal Cancer

Japan
Korean Cancer Study Group

Not yet recruiting

Gut Microbiome and Its Immune Modulation in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer
Yonsei University

Not yet recruiting

Development of a Genome-based Platform for Personalized Treatment in Locally Advanced Rectal Cancer Patients

Locally Advanced Rectal Cancer

Korea, Republic of
Fudan University

Recruiting

Short-course Radiotherapy Based TNT Combined With PD-1 Inhibitor for Locally Advanced Rectal Cancer (TORCH)

Locally Advanced Rectal Cancer

China
Fudan University

Recruiting

Perioperative Versus Postoperative CapOX Chemotherapy for Locally Advanced Colon Cancer

Locally Advanced Colon Cancer

China
Universitätsklinikum Hamburg-Eppendorf
Servier Affaires Médicales; Clinical Trial Center North (CTC North GmbH & Co...

Terminated

Evaluating Trifluridine/Tipiracil Based Chemoradiation in Locally Advanced Rectal Cancer - The Phase I/II TARC Trial

Locally Advanced Rectal Cancer

Germany
Fudan University

Unknown

A Study of Chinese Herbal Compound Dendrobium Huoshanense Granules in NCRT for Patients With Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Zhu Ji

Unknown

Tumor Response Prediction in Neoadjuvant Chemoradiation of Locally Advanced Rectal Cancer Using Metabonomics Analysis

Locally Advanced Rectal Cancer

China
Maastricht University Medical Center

Completed

Minimal Invasive Strategies for Good and Complete Response to Chemoradiation in Rectal Cancer

Locally Advanced Rectal Cancer

Netherlands
Zhejiang Cancer Hospital

Unknown

Nimotuzumab in Combination With Chemoradiation in Patients With Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

China
Vejle Hospital
Aarhus University Hospital

Terminated

Predictive Value of 18F-FAZA in Rectum Cancer (FAZA)

Locally Advanced Rectum Cancer

Denmark
BioNTech SE

Not yet recruiting

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

Triple Negative Breast Cancer | Locally Advanced Breast Cancer
Tango Therapeutics, Inc.

Recruiting

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

Locally Advanced Solid Tumor

United States, France
Fujian Cancer Hospital

Recruiting

Tislelizumab Combined With Apatinib and Oxaliplatin Plus S1 Vs Oxaliplatin Plus S1 as Neoadjuvant Therapy for Borrmann IV、Large Borrmann III Type and Bulky N Positive Advanced Gastric Cancer

Immunotherapy Gastrict Cancer

China
Fujian Cancer Hospital

Not yet recruiting

Study of the Apatinib Combine With POF Versus POF in Gastric Cancer

Gastric Adenocarcinoma | Advanced Cancer

China
Asan Medical Center

Completed

Venous Thromboembolism in Advanced Gastric Cancer Patients

Advanced Gastric Cancer

Korea, Republic of

Clinical Trials on Locally Advanced Gastric Cancer

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