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Clinical Trials on Locally Advanced or Metastatic Solid Carcinomas
Total 1860 results
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Oncolytics BiotechUniversity of TexasCompletedMetastatic or Recurrent Squamous Cell Carcinoma of the LungUnited States
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NATCO Pharma Ltd.RecruitingCarcinoma | Recurrent and/or Metastatic Head and Neck Squamous Cell CarcinomaUnited States, India
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Fox Chase Cancer CenterMerck Sharp & Dohme LLC; CelgeneTerminatedNonsmall Cell Lung Cancer | Relapsed or Refractory Solid TumorsUnited States
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Incyte CorporationTerminatedBreast Cancer | Pancreatic Cancer | Hodgkin's Lymphoma | Solid Tumor | Metastatic Cancer | Advanced Cancer | NHL (Non-Hodgkin Lymphoma) | UC (Ureter and Urethera)United States
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Cancer Institute and Hospital, Chinese Academy...RecruitingUntreated Advanced NSCLC Patients | FISH Identified ALK Fusion Positive or NegativeChina
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NuCana plcRecruitingMelanoma | Renal Cell Carcinoma | Gastric Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Neoplasm Malignant | Pleural... and other conditionsUnited Kingdom
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M.D. Anderson Cancer CenterActive, not recruitingMetastatic Rectal Adenocarcinoma | Stage III Rectal Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Rectal Cancer AJCC v8 | Stage IV Rectal Cancer AJCC v8 | Stage IVA Rectal Cancer AJCC v8 | Stage IVB Rectal Cancer AJCC v8 | Stage IVC Rectal Cancer AJCC... and other conditionsUnited States
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Roswell Park Cancer InstituteNational Cancer Institute (NCI)Active, not recruitingMetastatic Melanoma | Advanced Malignant Solid Neoplasm | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage... and other conditionsUnited States
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Shanghai Junshi Bioscience Co., Ltd.Active, not recruitingPrimary Disease: Unresectable or Metastatic Renal Cell Carcinoma Focus of the Study:PFS Assessed by IRC Per RECIST 1.1China
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Sarah GoldbergMirati Therapeutics Inc.TerminatedLung Diseases | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Metastatic Lung Non-Small Cell Carcinoma | PD-L1 Gene Mutation | Pembrolizumab | Stage IV Lung Non-Small Cell Cancer AJCC v7 | Advanced Treatment-Naïve PD-L1 | SitravatinibUnited States
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Barts & The London NHS TrustRoyal Marsden NHS Foundation Trust; Guy's and St Thomas' NHS Foundation Trust; Case Western Reserve University and other collaboratorsCompletedEndometrial Cancer | Surgically Staged Endometrial and Cervical Carcinoma | Cervical Cancer: Invasive Disease, FIGO Stage 1B1 or Higher | Stage 1A With Myometrial Invasion or Any Higher Stage and Grade 3 | Stage 1A With Myometrial Invasion or Any Other Higher Stage and Serous Papillary or... and other conditionsUnited Kingdom
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AmgenCompletedMetastatic or Recurrent Squamous Cell Carcinoma of Head and NeckUnited States, Belgium, Czechia, Spain, Austria, France, Lithuania, Puerto Rico, Slovakia
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Daiichi SankyoAstraZenecaAvailableAdvanced Non-Small Cell Lung Cancer | Metastatic Non Small Cell Lung CancerUnited States
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Xiuning LeM.D. Anderson Cancer Center; Eli Lilly and CompanyActive, not recruitingNon Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | EGFR Gene MutationUnited States
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National Cancer Institute (NCI)WithdrawnMetastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | Stage IIIB Hepatocellular Carcinoma AJCC v7 | Stage IIIC Hepatocellular Carcinoma AJCC v7 | Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma | Ann Arbor Stage III B-Cell Non-Hodgkin Lymphoma | Stage IV Hepatocellular Carcinoma AJCC... and other conditionsUnited States
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AstraZenecaPRA Health SciencesCompletedRecurrent or Metastatic PD-L1-positive Squamous Cell Carcinoma of the Head and NeckUnited States, Belgium, Canada, France, Spain, Korea, Republic of, Hungary, Malaysia, United Kingdom, Taiwan, Germany, Georgia, Israel, Czechia
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City of Hope Medical CenterNational Cancer Institute (NCI)WithdrawnAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions
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BeiGeneActive, not recruitingNon Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma (HNSCC) | Nasopharyngeal Carcinoma (NPC)Canada, Australia, New Zealand, Korea, Republic of, United States, Malaysia, Thailand
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University of WashingtonEli Lilly and CompanyRecruitingLocally Advanced Unresectable Digestive System Neuroendocrine Neoplasm | Metastatic Digestive System Neuroendocrine Neoplasm | Pancreatic Neuroendocrine Tumor | Advanced Digestive System Neuroendocrine Neoplasm | Digestive System Neuroendocrine Tumor | Foregut Neuroendocrine Tumor | Hindgut Neuroendocrine... and other conditionsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingStage III Pancreatic Cancer AJCC v8 | Borderline Resectable Pancreatic Adenocarcinoma | Resectable Pancreatic Ductal Adenocarcinoma | Locally Advanced Pancreatic Ductal AdenocarcinomaUnited States
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Jacobio Pharmaceuticals Co., Ltd.Not yet recruitingAdvanced Non-squamous Non-small-cell Lung Cancer | Metastatic Non-squamous Non Small Cell Lung Cancer
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Eli Lilly and CompanyTerminatedColorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid TumorUnited States, Australia
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National Cancer Institute (NCI)Active, not recruitingSarcoma | Metastatic Renal Cell Carcinoma | Metastatic Melanoma | Recurrent Renal Cell Carcinoma | Recurrent Melanoma | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Clinical Stage IV Cutaneous Melanoma... and other conditionsUnited States, Canada
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National Cancer Institute (NCI)CompletedNSCLC | Solid Tumors | Lymphomas | Granulosa Cell Ovarian Cancer | Metastatic Colon CarcinomaUnited States
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7 Hills Pharma, LLCRecruitingMelanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditionsUnited States
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Deciphera Pharmaceuticals LLCRecruitingMelanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene MutationUnited States
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University of WashingtonMerck Sharp & Dohme LLC; Prometheus LaboratoriesTerminatedMetastatic Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer | Advanced Clear Cell Renal Cell Carcinoma | Stage IV Renal Cell CancerUnited States
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GeneQuantum Healthcare (Suzhou) Co., Ltd.RecruitingHER2-positive Breast Cancer | HER2-positive Biliary Tract Cancer | HER2-Positive Salivary Gland Carcinomas | HER2-Positive Advanced Solid TumorChina, Australia, United States
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Fudan UniversityNot yet recruitingAdvanced Rectal Cancer | Liver Metastasis | Pulmonary Metastasis | Microsatellite Stable Colorectal CarcinomaChina
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City of Hope Medical CenterNational Cancer Institute (NCI)Active, not recruitingClear Cell Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Advanced Renal Cell Carcinoma | Unresectable Renal Cell CarcinomaUnited States
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Vanderbilt-Ingram Cancer CenterNational Cancer Institute (NCI)RecruitingMetastatic Clear Cell Renal Cell Carcinoma | Advanced Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8United States
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Forma Therapeutics, Inc.CompletedCohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme) | Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas) | Cohort 3a and 3b: Chondrosarcoma | Cohort 4a and 4b: Intrahepatic... and other conditionsUnited States, Korea, Republic of, Australia, United Kingdom, Spain, France
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Hoffmann-La RocheRecruitingMetastatic Melanoma | Non-small Cell Lung Cancer | Solid Tumors | Esophageal Squamous Cell CarcinomaUnited States, Denmark, Israel, Portugal, Singapore, Spain, United Kingdom, Mexico, Korea, Republic of, Brazil, Turkey, Moldova, Republic of, Georgia
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NiKang Therapeutics, Inc.PfizerRecruitingNeoplasms | Kidney Cancer | Kidney Neoplasms | Carcinoma, Renal Cell | Urologic Neoplasms | Urogenital Neoplasms | Neoplasms by Site | Kidney Diseases | Urologic Diseases | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Clear Cell Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Recurrent... and other conditionsUnited States
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University Hospital, BordeauxRecruitingMetastatic Renal Cell Carcinoma | Good or Only One Adverse Prognostic Factor Intermediate Risk Per IMDC ScoreFrance
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Syros PharmaceuticalsCompletedBreast Cancer | Pancreatic Cancer | Advanced Solid Tumor | Small-cell Lung CancerUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingMetastatic Undifferentiated Pleomorphic Sarcoma | Recurrent Undifferentiated Pleomorphic Sarcoma | Locally Advanced Undifferentiated Pleomorphic Sarcoma | Unresectable Undifferentiated Pleomorphic SarcomaUnited States
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Arsenal Biosciences, Inc.RecruitingRecurrence | Advanced/Metastatic Clear Cell Renal Cell CarcinomaUnited States
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Umeå UniversityKarolinska University Hospital; Sahlgrenska University Hospital, Sweden; University... and other collaboratorsRecruitingQuality of Life | Surgery | Pancreas Adenocarcinoma | Chemotherapy Effect | Pancreas Cancer | Pancreas Neoplasm | Pancreas Disease | Locally Advanced Pancreatic Adenocarcinoma | Borderline Resectable Pancreatic AdenocarcinomaSweden
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Ohio State University Comprehensive Cancer CenterRecruitingStage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Unresectable Lung Non-Small Cell Carcinoma | Locally Advanced Lung Non-Small...United States
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Angiochem IncCompletedAdvanced Solid Tumors With and Without Brain MetastasesUnited States
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Keythera Pharmaceuticals (Australia) Pty LtdRecruitingGastric Cancer | Colorectal Cancer | Lung Cancer | Bladder Cancer | Advanced Solid Tumor | Squamous Cell Carcinoma of the EsophagusAustralia
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GI Innovation, Inc.Merck Sharp & Dohme LLCRecruitingMelanoma | Sarcoma | Renal Cell Carcinoma | Cervical Cancer | Urinary Bladder Cancer | Vulvar Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Vaginal Cancer | Microsatellite Stable...Korea, Republic of, United States
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Arbeitsgemeinschaft medikamentoese TumortherapieMedical University of GrazTerminatedLocally Advanced Malignant Neoplasm | Squamous Cell Carcinoma of the Hypopharynx Stage III | Squamous Cell Carcinoma of the Hypopharynx Stage IV | Squamous Cell Carcinoma of the Oral Cavity Stage III | Squamous Cell Carcinoma of the Oral Cavity Stage IV | Laryngeal Squamous Cell Carcinoma Stage... and other conditionsAustria
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NextCure, Inc.TerminatedBreast Cancer | Ovarian Cancer | Non-small Cell Lung Cancer | Advanced or Metastatic Solid TumorsUnited States
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Institut de Recherches Internationales ServierCompletedGlioma | Cholangiocarcinoma | Chondrosarcoma | Other Advanced Solid TumorsUnited States, France
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Innovent Biologics (Suzhou) Co. Ltd.Not yet recruitingUnresectable or Metastatic Gastric or Gastroesophageal Junction AdenocarcinomaChina
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Taiho Oncology, Inc.CompletedBreast Cancer | Gastric Cancer | Cholangiocarcinoma | Urothelial Cancer | Primary CNS Tumors | Advanced and Metastatic Cancer Patients With Tumors Harboring FGF/FGFR TumorsFrance, United States, Korea, Republic of, United Kingdom, Japan, Hong Kong, Australia, Taiwan, Italy, Canada, Germany, Netherlands, Spain
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Yonsei UniversityActive, not recruitingHistologically Confirmed Unresectable or Metastatic Squamous Cell Carcinoma of the Esophagus Who Failed on Standard TreatmentKorea, Republic of
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Rahul AggarwalNational Cancer Institute (NCI); U.S. Army Medical Research Acquisition ActivityRecruitingProstate Cancer | Advanced Solid Tumor | Renal Cancer | Urethral Cancer | Solid Tumor, Adult | Metastatic Castration-resistant Prostate CancerUnited States